Navigation Links
John P. Cogswell, Ph.D., receives 2009 Alzheimer Award
Date:5/26/2009

need for diagnostic biomarkers of disease progression this paper additionally examines the microRNAs in the cerebrospinal fluid of late stage AD patients. Again AD-specific changes were detected although here microRNAs with known and potential combinatorial effects on T lymphocyte signaling and inflammation pathways were identified. Because the CSF contains memory T cells and antigen presenting cells involved in immune-surveillance of the brain, these data suggested that microRNA responses in CSF cells might be sentinels of the disease.

"More work is required to validate whether these changes are specific to AD, can be used to follow the course of AD or overlap with other neurodegenerative diseases involving inflammation," stated Dr. Cogswell. "However, the data highlight the potential of microRNAs to further understand sporadic Alzheimer's disease and provide accessible biomarkers to aid clinical diagnosis."

Dr. Cogswell, a former researcher at GlaxoSmithKline Inc., Research Triangle Park, NC, received his initial training from Duke University, Durham, North Carolina followed by postdoctoral fellowships in cellular and molecular immunology at the University of California, Los Angeles and University of North Carolina, Chapel Hill. In 16 years at GSK, Dr. Cogswell and colleagues developed high content qRT-PCR and histology applications that identified tractable targets from the human genome sequencing project and transcriptional biomarkers that decreased attrition in drug discovery.


'/>"/>

Contact: Astrid Engelen
a.engelen@iospress.nl
31-206-883-355
IOS Press
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Sally L. Glaser, Ph.D., Named CEO of the Northern California Cancer Center
2. Barry Arbuckle, Ph.D., President & CEO of MemorialCare Medical Centers to Chair Southern California March for Babies 2009, March of Dimes Largest Fundraising Events
3. Exagen Diagnostics Names John Alsobrook, Ph.D., Vice President and Chief Operating Officer
4. Jan Ake Gustafsson, M.D., Ph.D., Joins Bionovos Scientific Advisory Board
5. SCOLR Pharma, Inc. Announces Appointment of Bruce S. Morra, Ph.D., as President & CEO
6. Light Sciences Oncology Elects Former FDA Commissioner Frank Young, M.D., Ph.D., to Board of Directors
7. Daniel J. Nevrivy, Ph.D., Biotech and Pharmaceutical Patent Attorney, Launches New Law Firm Aimed at Helping Clients Preserve Their Capital
8. BioNanomatrix Appoints Gary Zweiger, Ph.D., as Vice President of Business Development
9. Alexander R. Giaquinto, Ph.D., Joins Regado Biosciences as Senior Vice President of Regulatory Affairs and Quality Assurance
10. Human Genome Sciences Appoints John L. Lamattina, Ph.D., to Its Board of Directors
11. Conatus Pharmaceuticals Appoints Anthony W. Fox, MD, Ph.D., as Chief Medical Officer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/14/2014)... orphaned by HIV/AIDS in South Africa may provide insight ... behavior issues in other areas of the world, which ... that could lead to successful interventions. , A ... United Nations mentions that due to the HIV/AIDS pandemic, ... African, children are at an increased risk for mental ...
(Date:4/14/2014)... A new study shows that moderate to severe ... risk of stroke, cancer and death. , Results of ... to severe obstructive sleep apnea were four times more ... times more likely to have a stroke (HR = ... (HR = 3.4), and 2.5 times more likely to ...
(Date:4/14/2014)... Dallas study involving serious youth offenders, the answer to one ... seven years: "How long do you think you,ll live?", According ... offending over time., Author Dr. Alex Piquero said the study ... of them offend at very high rates and commit more ... much later in life offend much less., "In a lot ...
(Date:4/14/2014)... with symptoms increasing dramatically during some of the most important ... has found. , Depressive symptoms increased on average by 68 ... young men, who were around 25 years old when they ... their children. The results of the study were published April ... is the first to identify when young fathers are at ...
(Date:4/14/2014)... Lower weight babies and babies who aren,t breastfed ... risk of developing chronic inflammation and related health ... study. , "There were good reasons to hypothesize ... inflammation in adulthood," says Thomas McDade (Northwestern University), ... in the Child & Brain Development program. "It ...
Breaking Medicine News(10 mins):Health News:Researchers identify children with emotional behavior difficulties 2Health News:Researchers identify children with emotional behavior difficulties 3Health News:Study links severe sleep apnea to increased risk of stroke, cancer and death 2Health News:UT Dallas study: Youth who fail to envision future commit more crimes 2Health News:Young dads at high risk of depression, too 2Health News:Low birth weight, less breastfeeding create later health risks 2
... Relationship with NBME and Announces ... Certification Program, TAMPA, Fla., Jan. 29 ... Physicians, Inc. (ABQAURP) is pleased to,announce the organization ... Medical Examiners(R) (NBME(SM)) to oversee and administer ABQAURP,s,professional ...
... MACON, Ga., Jan. 29 Arcadian Health Plan, ... for Medicare,beneficiaries, has enhanced its benefits for 2008 ... comes on the heels of successful rollouts in,Oklahoma, ... the Georgia plans include $0 premiums, free annual,physicals ...
... Health Plan, Inc., a,leading provider of Medicare Advantage ... for 2008 and expanded into the,state of North ... rollouts in,Oklahoma, Louisiana, Georgia, South Carolina and Maine., ... in most markets, free,annual physicals and flu shots, ...
... Jan. 29, 2008 -- The kidney actively cleans its most ... scientists from Washington University School of Medicine in St. Louis ... breakdown of this self-cleaning feature can make kidneys more vulnerable ... of this clearance mechanism can leave things on the filter ...
... Sugary Soft Drinks, ORLANDO, Fla., Jan. 29 Tired ... of calories and no nutritional value?,Pour your kids a glass ... solution to your SSDD (Sugary Soft Drink Dilemma)., "We ... their,children enjoy Sun Shower(TM) juices," said Chris New, founder, chairman,and ...
... Assume Key Management Posts as Senior Vice Presidents, ... (NYSE: AGP ) today announced the hiring ... key management positions: Linda,Whitley-Taylor has been named Executive ... AMERIGROUP as Senior Vice President, Senior,Litigation Counsel; and ...
Cached Medicine News:Health News:ABQAURP Renews Agreement with the National Board of Medical Examiners to Oversee Testing Methodology 2Health News:ABQAURP Renews Agreement with the National Board of Medical Examiners to Oversee Testing Methodology 3Health News:New Options for Medicare Beneficiaries in Georgia 2Health News:A New Beginning for Medicare Beneficiaries in North Carolina 2Health News:Breakdown of kidney's ability to clean its own filters likely causes disease 2Health News:Breakdown of kidney's ability to clean its own filters likely causes disease 3Health News:Looking for a Healthy Alternative for Your Children's Drinks? Try a Glass of Sun Shower(TM) 100% Nectarine Juice 2Health News:AMERIGROUP Names Linda Whitley-Taylor as Executive Vice President, Associate Services 2Health News:AMERIGROUP Names Linda Whitley-Taylor as Executive Vice President, Associate Services 3
(Date:1/15/2014)... 2014 BreedIT Corp (OTC: BRDT), ... distributor of highly sophisticated agro-breeding solutions for plant breeders ... the Company,s board of directors appointed chemistry and pharmaceutical ... new member of the board. From 1975 ... Pharmaceutical Industries Ltd (NYSE: TEVA ) and ...
(Date:1/15/2014)... Tegra Medical is very pleased to announce the appointment ... new Chief Executive Officer.  Mark was promoted from his ... has overseen the company,s four facilities in ... Costa Rica.  Mr. King joined Tegra Medical in 2012 ... manufacturing experience in medical device businesses, both in branded ...
(Date:1/15/2014)... 15, 2014 The Cadence Fitness & ... Fitness Center by the Medical Fitness Association, a ... centers to achieve their full potential. The Cadence ... fitness center in the western suburbs and second ... means the Cadence Fitness & Health Center meets ...
Breaking Medicine Technology:BreedIT (OTC: BRDT) Appoints Chemistry and Pharmaceutical Industry Expert Dr. Ben-Zion Weiner to Its Board of Directors 2BreedIT (OTC: BRDT) Appoints Chemistry and Pharmaceutical Industry Expert Dr. Ben-Zion Weiner to Its Board of Directors 3Tegra Medical Appoints New Chief Executive Officer 2Tegra Medical Appoints New Chief Executive Officer 3Cadence Fitness & Health Center Certified as Medical Fitness Facility 2Cadence Fitness & Health Center Certified as Medical Fitness Facility 3
... National Education Association Health Information Network (NEA HIN) is partnering ... resources for middle school teachers focusing on the critical health ... currently in production, and will be released in July 2012 ... D.C. They will be available in hard copy and online. ...
... Mass., Oct. 31, 2011 Royal Philips Electronics (AEX: ... Mammography, a full-field digital mammography (FFDM) solution that offers ... systems, without compromising image quality. The addition of MicroDose ... important step for the company,s focus on women,s health ...
Cached Medicine Technology:NEA Health Information Network and Purdue Pharma L.P. Partner to Help Kids be Safe 2Philips Enters North American Mammography Market, Underscoring its Global Commitment to Women's Health Care 2Philips Enters North American Mammography Market, Underscoring its Global Commitment to Women's Health Care 3Philips Enters North American Mammography Market, Underscoring its Global Commitment to Women's Health Care 4
Bausch & Lomb round and rectangular magnifiers incorporate precision optics and an ergonomic design for increased clarity and comfort during use...
Adjustable piston accommodates 7 - 9 mm trephine blade. Complete punch includes base plate, piston carrier, piston for 7 - 9 mm trephine blades and 18 mm diameter Teflon block. Designed for accurate ...
... allows the surgeon to effectively ... scrub-resistant, gentian violet ink. All ... sterile, with a ruler and ... pouches. Micro tip marker for ...
Broad tip, gentian violet, sterile, disposable...
Medicine Products: