Navigation Links
Jet Lag Upsets Brain's Internal Clocks
Date:4/18/2009

Finding could fine-tune treatments for sleepy travelers and shift workers, study suggests

FRIDAY, April 17 (HealthDay News) -- Jet lag-related sleep problems are caused by disruption of internal clocks in two neural centers, a finding that could lead to more effective treatments, say U.S. researchers.

The University of Washington research team found that jet lag upsets two separate, but linked, groups of neurons in a brain structure called the suprachiasmatic nucleus, below the hypothalamus at the base of the brain.

One group of neurons (ventral) is synchronized with deep sleep that results from physical fatigue, and the other group of neurons (dorsal) controls the dream state of rapid eye movement (REM) sleep, the researchers explained. Normally, these two groups of neurons are synchronized with each other, but they can be thrown out of synch by jet lag or shift work.

"When we impose a 22-hour light-dark cycle on animals, the ventral center can catch up, but the dorsal doesn't adapt and defaults to its own inner cycle," Horacio de la Iglesia, an associate professor of biology, said in a University of Washington news release.

When laboratory rats used to a 25-hour light-dark cycle were exposed to a 22-hour cycle, their deep sleep quickly adapted to the 22-hour cycle, but their REM sleep continued to follow a 25-hour cycle. This meant that REM sleep didn't occur in normal progression following deep sleep, the researchers noted.

"We found that after exposing rats to a shift of the light-dark timing that simulates a trip from Paris to New York, REM sleep needed six to eight days to catch up with non-REM, or deep, sleep, the sleep you usually experience in the first part of the night," de la Iglesia said.

The findings, published online April 16 in the journal Current Biology, may help fine-tune current jet lag treatments.

"We can go back to the treatments that are believed to be effective and see where they might be acting in the circuitry of these neuron centers, then refine them to be more effective," de la Iglesia said.

More information

The National Sleep Foundation has more about jet lag.



-- Robert Preidt



SOURCE: University of Washington, news release, April 16, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Brain Adjusts to Cope With Lifes Upsets
2. Accumulated Lead May Affect Older Womens Brains
3. Musicians Brains Tuned to Emotions in Sound
4. Thrill-Seekers Brains May Be Wired Differently
5. Cutting Calories May Boost Aging Brains
6. The worlds best brains descend on Canberra
7. Omega-3 Fatty Acid May Help Preemie Girls Brains
8. Brains of Bulimia Patients Wired Differently
9. Aging brains allow negative memories to fade
10. Playing Video Games May Boost Older Brains
11. New tool trains athlete brains to react 53 percent faster
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Jet Lag Upsets Brain's Internal Clocks
(Date:5/27/2016)... ... 2016 , ... W.S. Badger Co. Inc ., the maker of certified ... as one of the best small businesses for new dads by Fatherly, the digital ... businesses providing progressive benefits to new parents on the organization’s 2016 Best Places ...
(Date:5/27/2016)... ... ... This campaign aims to provide a path to improved education and awareness ... change. , As nearly 795,000 Americans suffering from a new or recurrent stoke each ... an estimated 129,000 of these people dying from stroke, it’s become our nation’s fifth-leading ...
(Date:5/27/2016)... Texas (PRWEB) , ... May 27, 2016 , ... ... satisfying Army body fat composition regulations. This is the first time that Coolsculpting ... normally screened at least every six months to ensure they meet the prescribed body-fat ...
(Date:5/27/2016)... ... 2016 , ... Each year Standard Process Inc. ... this year’s Life University winner of a $2,500 scholarship from Standard ... Awards ceremony. , Outerbridge is approaching her last quarter at Life University in ...
(Date:5/26/2016)... ... 26, 2016 , ... There are many ways to cook a hot dog, ... that Americans prefer their dogs straight off the grill. Of the 90 percent of ... way to cook a hot dog, far outpacing other cooking methods such as steaming ...
Breaking Medicine News(10 mins):
(Date:5/27/2016)... Amarantus BioScience Holdings, Inc. (OTCQX: AMBS), ... and Orphan Diseases, today announced that President & CEO Gerald ... SeeThru Equity MicroCap Conference   Where: ... , NY When: Tuesday, May 31 st , ... Where: Grand Hyatt Hotel, 109 East 42 nd St, ...
(Date:5/26/2016)... 2016   Change Healthcare , a ... solutions and technology-enabled services designed to enable ... a strategic channel partnership with SourceMed, the ... and revenue cycle management services that empower ... clinics to optimize revenue, operational efficiency and ...
(Date:5/25/2016)... and GERMANTOWN, Maryland , May ... QGEN ; Frankfurt Prime Standard: QIA) today announced that ... with Therawis Diagnostics GmbH to develop and commercialize predictive assays ... market PITX2 as a marker to predict effectiveness of anthracycline ... "We are pleased to partner with Therawis, which ...
Breaking Medicine Technology: