Navigation Links
Jefferson scientists' discovery may help explain smoking-pancreatic cancer link
Date:4/14/2008

transcriptional but also translational (protein secretion) levels in pancreatic cancer cells, Dr. Arafat explains. Pancreas tissue samples from pancreatic cancer patients also showed higher than normal levels of the protein.

Dr. Arafat believes that osteopontin could be a drug target. We are now proposing that perhaps blocking osteopontin can interfere with the progression of pancreatic cancer and other cancers, she says, adding that her team would like to understand more about osteopontins effects on pancreatic cancer cell behavior. Dr. Arafats group now is comparing differences in osteopontin expression between smokers and non-smokers.

For example, if you put the cells with nicotine and block osteopontin, will the cells still be migratory? Is it osteopontin or something else in combination that is at work here?

Pancreatic cancer, the fourth-leading cause of cancer death in this country, takes some 34,000 lives a year. The disease is difficult to treat; it frequently is detected after it has spread. Only 4 percent of individuals with pancreatic cancer live for five years after diagnosis, and about 25 percent of those who undergo successful surgical removal of their disease live at least that long.


'/>"/>

Contact: Steve Benowitz
steven.benowitz@jefferson.edu
215-955-5291
Thomas Jefferson University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Jefferson specialists studying innovative surgery for effectively treating sleep apnea
2. Jefferson immunology researchers halt lethal rabies infection in brain
3. Jefferson radiation oncologists use real-time system to plant seeds against cancer
4. Jefferson researchers find personalized interventions key to improving colon cancer screening rates
5. Jefferson researchers uncover new evidence of prolactins possible role in breast cancer
6. MicroRNAs may be key to HIVs ability to hide, evade drugs, Jefferson scientists find
7. Jefferson scientists find protein may be key in developing deadly form of pancreatic cancer
8. Jefferson oncologists show focused radiation is effective as surgery against nerve tumor
9. Jefferson researchers find stem cells in degenerating spinal discs, potential for repair
10. Jefferson researchers show chemotherapy and radiation together extend lung cancer patients lives
11. Jefferson neuroscientists show anti-inflammation molecule helps fight MS-like disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... A group of Americans is headed to a ... left unchecked, could create a catastrophic, global pandemic. No, it’s ... John Rogers, the Executive Director the Eugene Bell Foundation and ... disease most think mankind conquered long ago: tuberculosis. , “Tuberculosis, ... on the comeback in several countries - what’s especially disconcerting ...
(Date:9/30/2014)... TUESDAY, Sept. 30, 2014 (HealthDay News) -- Medicare should ... at high risk for the disease, a coalition of ... The coalition, which includes the Lung Cancer Alliance, the ... the American Cancer Society and the American Society of ... Monday to the U.S. Centers for Medicare & Medicaid ...
(Date:9/30/2014)... gene mutation that causes a rare premature aging disease ... the rapid, unstoppable cell division that makes cancer so ... and the U-M Health System recently discovered a protein ... which precious hematopoietic stem cells can,t regenerate and make ... prone to cancer and bone marrow failure. , ...
(Date:9/30/2014)... Healthpointe is proud to announce that ... and ankle reconstruction surgeries to assist patients with severe ... specializes in the diagnosis and treatment of sports medicine, ... also trained to perform advanced Foot and Ankle Reconstruction ... is also fluent in Spanish. , Reconstructive surgical procedures ...
(Date:9/30/2014)... September 30, 2014 Jiwa Law Corporation, a ... that it will now be offering free consultation for personal ... visit the law firm for the first time to meet ... be given the opportunity to understand what their rights are. ... with the client to explain to them what the law ...
Breaking Medicine News(10 mins):Health News:US Delegation Heads to North Korea to Combat Tuberculosis Epidemic 2Health News:Groups Call for Medicare Coverage of Lung Cancer Screening 2Health News:Disease decoded: Gene mutation may lead to development of new cancer drugs 2Health News:Fellowship-Trained and Board-Certified Orthopedic Specialist Now Performing Advanced Foot & Ankle Reconstruction Surgeries 2Health News:Fellowship-Trained and Board-Certified Orthopedic Specialist Now Performing Advanced Foot & Ankle Reconstruction Surgeries 3Health News:Jiwa Law Corporation Now Offers Personal Injury Consultation Without Any Charge 2
... Calif., April 22 DURECT,Corporation (Nasdaq: DRRX ... Executive Officer, will be presenting at the Morgan ... 2008 at 8:30 a.m. ET.,The conference is being ... (Logo: http://www.newscom.com/cgi-bin/prnh/20020717/DRRXLOGO ), A live ...
... Therapeutics,(Amex: CXM ) and its operating unit ... System will be featured on Science,Channel,s "Cool Stuff: ... will,feature InnerCool,s endovascular cooling during a 6-hour brain ... 25, 2008 at 8:00 p.m. (ET/PT). Please,visit ...
... prices have risen,sharply over the last 12 months, organic ... expected to continue in 2008, according to,the Organic Trade ... safer than conventional foods, they are also more expensive.,Because ... looking,to strike a balance between their desire to eat ...
... April 21, 2008 3M Health Care, a leader ... announces plans to introduce the 3M Rapid Detection Flu ... qualitative and objective electronic results in 15 minutes. , ... season, the Rapid Detection Flu Test quickly delivers objective ...
... GeneGo, Inc., the leading,provider of software and databases ... the Chinese University of Hong Kong,Pediatric department will ... drug targets for a large variety of diseases ... to license MetaCore, as well as,species-specific content for ...
... POUGHKEEPSIE, N.Y., April 22 Just in time ... ) is rolling,out a new line of high-end ... -- and the well-being of its customers., ... covers made of bamboo -- a renewable resource ...
Cached Medicine News:Health News:Cardium Announces InnerCool's Endovascular Cooling to be Featured on Science Channel's Series 'Cool Stuff: How It Works' 2Health News:Cardium Announces InnerCool's Endovascular Cooling to be Featured on Science Channel's Series 'Cool Stuff: How It Works' 3Health News:Cardium Announces InnerCool's Endovascular Cooling to be Featured on Science Channel's Series 'Cool Stuff: How It Works' 4Health News:Eat Well, Save Money: BJ's Offers Everyday Low Prices on Top Quality Organic Groceries, Natural Foods Versus Supermarket Prices 2Health News:Eat Well, Save Money: BJ's Offers Everyday Low Prices on Top Quality Organic Groceries, Natural Foods Versus Supermarket Prices 3Health News:3M Health Care announces new 3M Rapid Detection Flu A+B test 2Health News:GeneGo's First Customer in Hong Kong; The Chinese University of Hong Kong 2Health News:Bragada(R) Luxury Mattress, Inc. Goes Green 2
(Date:9/30/2014)... 30, 2014 Passport Health, one of the ... has launched FluFree.com, a website designed to promote, educate ... For 20 years, Passport Health has provided its clients ... launch of FluFree.com is designed to address the growing ... of people who actually chose to get vaccinated. ...
(Date:9/30/2014)... 2014   Acutus Medical, Inc. (ACM), ... 3D Cardiac Chamber Imaging and Dipole Density Mapping system ... sustain complex cardiac arrhythmias, including atrial fibrillation, announced it ... its imaging/mapping system as well as bring to market ... Medical to complete work on the AcQMap TM ...
(Date:9/30/2014)... , Sept. 30, 2014 Headquartered in ... is a diversified company comprised of several specialized partners ... technology and the proven expertise of its team of ... wellness. WholeHealth Products, line of more than 10 professional ... and its more than 8 retail consumer tests is ...
Breaking Medicine Technology:Passport Health Launches FluFree.com - Aims To Improve Flu Vaccination Rates and Fulfill Growing Public Health Priority 2Passport Health Launches FluFree.com - Aims To Improve Flu Vaccination Rates and Fulfill Growing Public Health Priority 3Acutus Medical, Inc. Completes Additional $26.2M Series B Financing to Fund Portfolio Expansion 2Acutus Medical, Inc. Completes Additional $26.2M Series B Financing to Fund Portfolio Expansion 3WholeHealth Products Announces The Discovery Of The "Autism And Fragile X" Microwell And Rapid Diagnostic Test 2
... , ARDEE, Ireland, Nov. 19 Warner Chilcott ... its previously announced secondary offering of 20,000,000 of its ordinary ... share. The selling shareholders include funds affiliated with Bain ... CCMP Capital) and Thomas H. Lee Partners, L.P., certain other ...
... , ... leading global,supplier of active pharmaceutical ingredients (APIs), announced ... Safety Certification from,SafeBridge(R) Consultants, Inc. The Certification confirms ... potent active,pharmaceutical ingredients (APIs), and applies to specific ...
Cached Medicine Technology:Warner Chilcott Prices Secondary Equity Offering 2Warner Chilcott Prices Secondary Equity Offering 3Warner Chilcott Prices Secondary Equity Offering 4ScinoPharm Announces SafeBridge Potent Compound Safety Certification 2
1 mm smooth 45 degrees angled jaws. Cross action serrated handle with polished finish....
14 mm oval solid lower plate and straight 9 mm serrated upper jaw. Locking thumb screw and serrated handle with polished finish....
Solid lower plate with outside width 28 mm. Open upper plate. Serrated handle with locking thumb screw and polished finish. Right....
Oval solid 17 mm wide lower plate. Open upper plate with inside dimensions 12 mm x 14 mm. Serrated handle with locking thumb screw and polished finish. Most popular size or model....
Medicine Products: