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Jefferson researchers receive $3.9 million in Challenge grants
Date:11/3/2009

rs to study the role of a colorectal cancer marker called GUCY2C in detecting occult metastases in African-American patients with the disease. Currently, there are disparities in the outcomes of African-American vs. Caucasian patients diagnosed with early-stage colon cancer.

"We believe that African-American patients might have a higher rate of occult metastases in the lymph nodes," Dr. Waldman said. "We also believe this can be overcome using molecular analyses compared to routine pathological analyses."

Dr. Waldman and his team will conduct a retrospective analysis comparing the results of African-American patients and Caucasian patients diagnosed with early-stage colorectal cancer. They will look at the utility of using GUCY2C as a variable to identify occult metastases in the lymph nodes, and see how the tumor burden of GUCY2C compares between African-American and Caucasian patients.


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Contact: Emily Shafer
emily.shafer@jefferson.edu
215-955-6300
Thomas Jefferson University
Source:Eurekalert

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