Navigation Links
Jefferson researcher awarded NIH grant

PHILADELPHIA Scott Mintzer, M.D., assistant professor in the Department of Neurology at Jefferson Medical College of Thomas Jefferson University, and director of the Epilepsy Monitoring Unit at the Jefferson Comprehensive Epilepsy Center of Jefferson Hospital for Neuroscience was recently awarded a Junior Investigator grant from the National Institutes of Health (NIH) to study the adverse metabolic effects of antiepileptic seizure medications. The K23 grant, also known as the Mentored Patient-oriented Research Career Development Award, totals $843,000 and will be dispersed over a five-year period.

The K23 award is to support the career development of investigators who have made a commitment to focus their endeavors on patient-oriented research. This mechanism provides support for three to five years of supervised study and research for clinically trained professionals who have the potential to develop into productive, clinical investigators focusing on patient-oriented research.

"I am honored to have been chosen to receive such a prestigious grant," said Dr. Mintzer. "It's my hope that this research into the possible cardiovascular side effects of anti-seizure medications may help doctors manage the care of patients with seizures more effectively while not adversely affecting other aspects of their overall health."

The grant involves two randomized patient studies designed to ascertain the metabolic effects of common anti-seizure medications on risk factors for heart attack and stroke including cholesterol and C-reactive protein levels. The first study includes 90 patients with epilepsy, who will be followed over several months, to look at whether changes in seizure medication can improve cholesterol and other blood chemical levels on a short-term and long-term basis.

The second study follows 200 patients who have had a subarachnoid hemorrhage, or bleeding in the lining that surrounds the brain. Traditionally this patient population is prescribed anti-seizure medications for a certain period of time following treatment. Trial participants will be randomly broken into four groups and prescribed either Dilantin, Keppra, Depakote or no medication to see if there are any potential short- or long-term effects on cardiovascular risk factors.


Contact: Ed Federico
Thomas Jefferson University

Related medicine news :

1. Jefferson specialists studying innovative surgery for effectively treating sleep apnea
2. Jefferson immunology researchers halt lethal rabies infection in brain
3. Jefferson radiation oncologists use real-time system to plant seeds against cancer
4. Jefferson researchers find personalized interventions key to improving colon cancer screening rates
5. Jefferson researchers uncover new evidence of prolactins possible role in breast cancer
6. MicroRNAs may be key to HIVs ability to hide, evade drugs, Jefferson scientists find
7. Jefferson scientists find protein may be key in developing deadly form of pancreatic cancer
8. Jefferson oncologists show focused radiation is effective as surgery against nerve tumor
9. Jefferson researchers find stem cells in degenerating spinal discs, potential for repair
10. Jefferson researchers show chemotherapy and radiation together extend lung cancer patients lives
11. Jefferson neuroscientists show anti-inflammation molecule helps fight MS-like disease
Post Your Comments:
(Date:10/13/2017)... ... October 13, 2017 , ... As health professionals work ... as “patient engagement.” The patient is doing more than filling out a survey; in ... “There is an increasing emphasis in health care and research on the importance of ...
(Date:10/13/2017)... Las Vegas, Nevada (PRWEB) , ... October 13, 2017 , ... ... of 7® Hemp CBD Oil utilizing Purzorb™ technology. Applying the Purzorb™process to full spectrum ... CBD dose required and providing a CBD form that can be easily incorporated into ...
(Date:10/13/2017)... ... 13, 2017 , ... Many families have long-term insurance that covers care for ... a waiver for care if the client has a cognitive impairment diagnosis. , ... care, is often waived, so the benefits from their insurance start immediately,” said Mechell ...
(Date:10/13/2017)... ... October 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The ... the most popular and least understood books in the Holy Scriptures, Revelation. The Book ... have baffled scholars for centuries. Many have tossed it off as mere rubbish, but ...
(Date:10/13/2017)... ... October 13, 2017 , ... “America On The Brink”: the ... “America On The Brink” is the creation of published author, William Nowers. Captain ... As a WWII veteran, he spent thirty years in the Navy. Following his ...
Breaking Medicine News(10 mins):
(Date:10/7/2017)... Texas , Oct. 6, 2017   Provista, ... with more than $100 billion in purchasing power, today ... news and information. The Newsroom is the ... and industry trends, infographics, expert bios, news releases, slideshows ... having access to a wealth of resources at their ...
(Date:10/4/2017)... -- According to the Centers for Disease Control and Prevention (CDC), influenza ... Care is helping communities across Massachusetts , ... no-cost* flu shots through the end of the month. *Some ... ... flu shot is by the end of October, according to the Centers ...
(Date:10/2/2017)... , Oct. 2, 2017  Eli Lilly and Company ... results for the third quarter of 2017 on Tuesday, ... call on that day with the investment community and ... The conference call will begin at 9 a.m. ... access a live webcast of the conference call through ...
Breaking Medicine Technology: