Navigation Links
Jefferson researcher awarded NIH grant
Date:12/4/2008

PHILADELPHIA Scott Mintzer, M.D., assistant professor in the Department of Neurology at Jefferson Medical College of Thomas Jefferson University, and director of the Epilepsy Monitoring Unit at the Jefferson Comprehensive Epilepsy Center of Jefferson Hospital for Neuroscience was recently awarded a Junior Investigator grant from the National Institutes of Health (NIH) to study the adverse metabolic effects of antiepileptic seizure medications. The K23 grant, also known as the Mentored Patient-oriented Research Career Development Award, totals $843,000 and will be dispersed over a five-year period.

The K23 award is to support the career development of investigators who have made a commitment to focus their endeavors on patient-oriented research. This mechanism provides support for three to five years of supervised study and research for clinically trained professionals who have the potential to develop into productive, clinical investigators focusing on patient-oriented research.

"I am honored to have been chosen to receive such a prestigious grant," said Dr. Mintzer. "It's my hope that this research into the possible cardiovascular side effects of anti-seizure medications may help doctors manage the care of patients with seizures more effectively while not adversely affecting other aspects of their overall health."

The grant involves two randomized patient studies designed to ascertain the metabolic effects of common anti-seizure medications on risk factors for heart attack and stroke including cholesterol and C-reactive protein levels. The first study includes 90 patients with epilepsy, who will be followed over several months, to look at whether changes in seizure medication can improve cholesterol and other blood chemical levels on a short-term and long-term basis.

The second study follows 200 patients who have had a subarachnoid hemorrhage, or bleeding in the lining that surrounds the brain. Traditionally this patient population is prescribed anti-seizure medications for a certain period of time following treatment. Trial participants will be randomly broken into four groups and prescribed either Dilantin, Keppra, Depakote or no medication to see if there are any potential short- or long-term effects on cardiovascular risk factors.


'/>"/>

Contact: Ed Federico
ed.federico@jefferson.edu
Thomas Jefferson University
Source:Eurekalert

Related medicine news :

1. Jefferson specialists studying innovative surgery for effectively treating sleep apnea
2. Jefferson immunology researchers halt lethal rabies infection in brain
3. Jefferson radiation oncologists use real-time system to plant seeds against cancer
4. Jefferson researchers find personalized interventions key to improving colon cancer screening rates
5. Jefferson researchers uncover new evidence of prolactins possible role in breast cancer
6. MicroRNAs may be key to HIVs ability to hide, evade drugs, Jefferson scientists find
7. Jefferson scientists find protein may be key in developing deadly form of pancreatic cancer
8. Jefferson oncologists show focused radiation is effective as surgery against nerve tumor
9. Jefferson researchers find stem cells in degenerating spinal discs, potential for repair
10. Jefferson researchers show chemotherapy and radiation together extend lung cancer patients lives
11. Jefferson neuroscientists show anti-inflammation molecule helps fight MS-like disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/10/2016)... ... February 10, 2016 , ... MetLoop ... revolutionary new 2.0 version at the International Roofing Expo in Orlando, Florida on ... the world's most advanced weather technology in the hands of consumers, roofing contractors, ...
(Date:2/10/2016)... ... February 10, 2016 , ... InDemand Interpreting , a ... partnered with Heart City Health Center to improve access to language ... City Health Center has provided the Elkhart community with access to high quality, ...
(Date:2/10/2016)... ... February 10, 2016 , ... Compliancy Group LLC ... of medical professionals throughout the country. The Guard was specifically designed to handle ... procedures, employee training, regulatory updates, and compliance coaching. , In addition to meeting ...
(Date:2/10/2016)... ... February 10, 2016 , ... Emergency rooms provide emergency care to stabilize critical ... leave patients with dental emergencies at risk of losing a tooth or their smiles. ... , Common dental emergencies include:, , Avulsed or knocked-out ...
(Date:2/10/2016)... ... February 10, 2016 , ... Dr. Peyman ... is now offering a variety of comprehensive procedures for facial enhancement. The treatments ... volume restoration, lip enhancement and nasal reshaping. , As a result, patients ...
Breaking Medicine News(10 mins):
(Date:2/10/2016)... Feb. 10, 2016  LexisNexis® Risk Solutions, a ... announced the launch of LexisNexis Provider Performance ... helps improve and optimize the quality and efficiency ... using severity-adjusted scores. By measuring provider performance through ... to deliver better outcomes, improve the patient experience ...
(Date:2/10/2016)... CORAL SPRINGS, Florida , February 10, 2016 ... Adamas Pharmaceuticals, Inc. (NASDAQ: ADMS ) and Celldex Therapeutics, ... Medivation, Inc. (NASDAQ: MDVN ), Adamas Pharmaceuticals, Inc. (NASDAQ: ... ). --> Today,s latest Orphan Drug Designations become ... granted by the FDA to novel drugs and biologics which ...
(Date:2/10/2016)... , Feb. 10, 2016 /PRNewswire/ - The President ... has announced the release of an anti-radiation product ... a revolutionary breakthrough in the treatment of cancer ... exposure. It will assist in the healing of ... It will also protect only the healthy cells ...
Breaking Medicine Technology: