Navigation Links
Jefferson oncologists show focused radiation is effective as surgery against nerve tumor
Date:10/30/2007

(PHILADELPHIA) Specifically aimed, stereotactic radiation may be as good as surgery and in some cases, even better in treating benign but potentially devastating brain tumors called non-acoustic schwannomas, according to a study by rradiation oncologists at the Kimmel Cancer Center at Thomas Jefferson University and Thomas Jefferson University Hospital in Philadelphia.

While surgery the standard treatment is effective and the only way to remove the tumor, its tricky and can potentially damage surrounding cranial nerves, including those associated with facial movement, eyesight and hearing. Some non-acoustic schwannomas wrap around various structures in the brain and cannot be completely removed. Treating the tumor with radiation is usually effective, less risky, and the vast majority of tumors do not grow back, notes Maria Werner-Wasik, M.D., associate professor of Radiation Oncology at Jefferson Medical College of Thomas Jefferson University.

Timothy Showalter, M.D., a resident in Radiation Oncology, Dr. Werner-Wasik, David Andrews, M.D., professor of Neurological Surgery at Jefferson Medical College, and their co-workers identified 39 patients with non-acoustic schwannomas who received radiation therapy at Thomas Jefferson University Hospital from 1996 to 2007. Patients either received stereotactic radiosurgery (SRS), which entails precise delivery of a single, focused, high dose of radiation to a specific area of the brain, or fractionated stereotactic radiation (FSR), where treatments are received over days or weeks. Roughly one-half of the patients had surgery to remove part of the tumor before radiation; the other half had only radiation. They found that stereotactic radiation, whether delivered in a single dose or in many doses over time, provided excellent local tumor control.

We found that we can improve the symptoms whether they get a single dose of radiation or several smaller doses, and it seems to be permanent, with few bad side effects, Dr. Werner-Wasik says. That would be extremely unlikely to expect with a surgical approach. They report their results on October 30, 2007 at the annual meeting of the American Society for Therapeutic Radiology and Oncology in Los Angeles.

Radiation has always been used in addition to surgery. But, Dr. Werner-Wasik points out, The use of stereotactic radiation allows safer use of radiation and can be applied in a wider variety of patients. While the standard of care has been surgery for most patients, the pendulum is swinging to radiation becoming the new standard as an initial treatment.

Dr. Showalter notes that the team would like to conduct trials testing the effectiveness of smaller doses of radiation, and examine which radiation type is more effective.

Schwannomas form on cranial nerves in the brain. Symptoms vary, depending on which cranial nerves are affected, and can include headache, hearing loss, facial pain or numbness, muscle weakness, difficulty swallowing and double vision. Non-acoustic schwannomas are rare, representing about 10 percent of the approximately 3,000 cases of schwannomas that occur annually in the United States.


'/>"/>

Contact: Steve Benowitz
steven.benowitz@jefferson.edu
215-955-5291
Thomas Jefferson University
Source:Eurekalert

Related medicine news :

1. Jefferson Physicians Report on Potentially Fatal Complication of Heart Attack
2. Jefferson Researchers Want to Learn If Heart Defect at Heart of Some Migraines
3. Oncologists Overlook Clot Risk
4. Focused Treatment For Childhood Cancer
5. DNA transcription to be focused
6. Fibroid Symptoms in Women can Be Relieved by Focused Ultrasound
7. Cognitive Skills Focused Curriculum may Lessen Kids Behavioural Problems
8. Antioxidants protect health tissue in people undergoing radiation therapy.
9. Radiation for Bone Pain
10. Radiation for Bone Pain
11. Gene enchances radiation therapy - A novel approach to fight cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits of moderation, ... the latter, setting the bar too high can result in disappointment, perhaps even self-loathing. ... toward their goal. , Research from PsychTests.com reveals that behind the ...
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was ... his family verbally and physically. , “When something upset him, he couldn’t control his emotions,” ... He would throw rocks at my other children and say he was going to kill ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... Comfort ... the American Cancer Society and the Road To Recovery® program to drive cancer patients ... seniors and other adults to ensure the highest quality of life and ongoing independence. ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Haute Beauty Network, ... M. Weintraub as a prominent plastic surgeon and the network’s newest partner. ... the most handsome men, look naturally attractive. Plastic surgery should be invisible.” He ...
(Date:6/24/2016)... ... , ... Venture Construction Group (VCG) sponsors Luke’s Wings ... the Woodmont Country Club at 1201 Rockville Pike, Rockville, Maryland, 20852. The event ... that have been wounded in battle and their families. Venture Construction Group is a ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... June 24, 2016  Arkis BioSciences, a leading ... and more durable cerebrospinal fluid treatments, today announced ... Series-A funding is led by Innova Memphis, followed ... other private investors.  Arkis, new financing will accelerate ... the market release of its in-licensed Endexo® technology. ...
(Date:6/23/2016)... ITASCA, Ill. , June 23, 2016  In a startling ... states are failing their residents by lacking a comprehensive, proven plan ... , a definitive ranking of how states are tackling the ... rating to only four states – Kentucky , ... and Vermont . Of the 28 failing states, ...
(Date:6/23/2016)... , June 23, 2016 Bracket , a ... its next generation clinical outcomes platform, Bracket eCOA (SM) ... on June 26 – 30, 2016 in Philadelphia ... electronic Clinical Outcome Assessment product of its kind to fully ... Bracket eCOA 6.0 is a flexible platform for ...
Breaking Medicine Technology: