Navigation Links
Jefferson awarded multi-million dollar NIH grant
Date:12/9/2009

PHILADELPHIA The Department of Neurology at Jefferson Medical College (JMC) of Thomas Jefferson University has been awarded a multi-million dollar grant from the National Institutes of Health (NIH) for the creation of a center of excellence to study autoimmune diseases from basic science research to its translation into clinical applications. The five-year grant initially totals over $4 million, but could be as much as $10 million by the end of award period. The center is one of nine in the country and the only one in the Pennsylvania.

"Our priority for this award and center is to translate basic science research into practical, clinical applications in autoimmune diseases," said Abdolmohamad Rostami, M.D. Ph.D., professor and chair of the Department of Neurology at JMC and at Thomas Jefferson University Hospital; director of the Multiple Sclerosis and Neuroimmunology Research Laboratory; and director of the new center. "Primarily we will be focusing on multiple sclerosis (MS), and systemic lupus erthematosus (SLE), but we will also be investigating other autoimmune diseases like scleroderma. The center's team will investigate how these diseases are produced, with the ultimate goal of finding new and successful ways to treat them."

Currently, Dr. Rostami is investigating the role of Th17 cells, a pro-inflammatory T-cell subset, in MS and ways to suppress these cells in hope of finding better treatments for the disease. His laboratory has shown that interkeukin-27, a cytokine produced by T-cells, can suppress Th17 cells. They have also shown that IL-27 can block the onset or reverse the disease in animals with MS-like disorder. "It appears that one of the ways that recovery from an MS exacerbation occurs is that part of the immune system is shut off, suppressing the immune response in the brain. IL-27 through suppression of Th17 cells appears to be crucial in this process," said Dr. Rostami.


'/>"/>

Contact: Ed Federico
ed.federico@jefferson.edu
Thomas Jefferson University
Source:Eurekalert

Page: 1

Related medicine news :

1. Jefferson specialists studying innovative surgery for effectively treating sleep apnea
2. Jefferson immunology researchers halt lethal rabies infection in brain
3. Jefferson radiation oncologists use real-time system to plant seeds against cancer
4. Jefferson researchers find personalized interventions key to improving colon cancer screening rates
5. Jefferson researchers uncover new evidence of prolactins possible role in breast cancer
6. MicroRNAs may be key to HIVs ability to hide, evade drugs, Jefferson scientists find
7. Jefferson scientists find protein may be key in developing deadly form of pancreatic cancer
8. Jefferson oncologists show focused radiation is effective as surgery against nerve tumor
9. Jefferson researchers find stem cells in degenerating spinal discs, potential for repair
10. Jefferson researchers show chemotherapy and radiation together extend lung cancer patients lives
11. Jefferson neuroscientists show anti-inflammation molecule helps fight MS-like disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/25/2016)... ... 25, 2016 , ... Today Omega Institute, a leading destination for yoga education ... training opportunities in the growing field of yoga therapy . Yoga therapy ... with specific health issues—including injuries, illnesses, and temporary or chronic health conditions. , “Yoga ...
(Date:5/25/2016)... ... 2016 , ... DKT International, one of the largest private ... to release their 2015 global impact data. In 2015, DKT served over 30 ... and 3.8 million unsafe abortions across 21 countries worldwide. , “We are ...
(Date:5/25/2016)... ... May 25, 2016 , ... ... supporting the real time adjudication of medical service claims by Pharmacy Benefit Managers ... current medical claims management software. The TransactRx Cross Benefit Clearinghouse receives standard professional ...
(Date:5/25/2016)... FRANCISCO, CA (PRWEB) , ... May 25, 2016 , ... ... School of Nursing and Health Professions. She will lead a team of more than ... Team. Baker will begin her role as dean in late August. , Baker comes ...
(Date:5/25/2016)... BEACH COUNTY, FLA (PRWEB) , ... May 25, 2016 , ... ... the latest technology to help turn back the hands of time of female aging. ... female aging and childbirth. Women with symptoms such as leakage, laxity, itchiness and ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... 24, 2016 Celsion Corporation (NASDAQ: ... today provided an update on its ongoing OVATION ... combining GEN-1, the Company,s DNA-based immunotherapy, with the ... patients with advanced ovarian cancer who will undergo ... is an IL-12 DNA plasmid vector formulated as ...
(Date:5/24/2016)... 24, 2016 ... , la première endoprothèse à double thérapie ... l,intervention portant sur les membres inférieurs et ... OrbusNeich, entreprise mondiale spécialisée dans la fourniture ... vie, a élargi son portefeuille pour inclure ...
(Date:5/23/2016)... According to a new ... Product (Wheelchair, Scooters, Medical Beds, Bathroom Safety, Mechanical, ... Wound), Accessories (Lifting, Transfer) & by End User ... MarketsandMarkets, the patient handling equipment market is expected ... a CAGR of 10.5% during the forecast period ...
Breaking Medicine Technology: