Navigation Links
Japanese encephalitis virus causes 'double trouble' to brain
Date:7/7/2008

Japanese encephalitis (JE), commonly known as brain fever, is one of the prevalent mosquito-borne encephalitis in India and entire South East (SE) Asia. Besides resulting in thousand fatalities each year, JE virus (JEV) infection causes prominent neurological sequelae in approximately one-third of the survivors. Even those patients in the good recovery group commonly encounter psychiatric problems, which include mental retardation, learning disabilities, speech and movement disorders and behavioural abnormalities.

Recent research in National Brain Research Center, Manesar, India by Dr. Anirban Basu and his graduate student, Sulagna Das have shown that JE virus damages the brain in two ways, by not only killing brain cells but by preventing the birth of new cells from neural stem/progenitor cells (NPC) and depleting the NPC pool in the brain. "It's a double hit to the brain, the JE virus causes brain injury by killing neurons as well as prevents its repair" lead researcher and the senior author of the work Anirban Basu said in a statement.

The children are more vulnerable targets of this virus, which causes massive neuronal loss in the Central Nervous System. "Children are at a dynamic stage of brain development, hence infection at this stage can have devastating effects on mental functions later in life. Our study has tried to explore how JEV infection leads to development of long-term cognitive deficits in the survivors", says Dr. Anirban Basu who has been working in the neurobiology of JEV infection for the past 4 years. These findings have been published online in a paper in Journal of Neurochemistry for inclusion in a future issue of the journal.

"The breakthrough here is that the JE virus prevents neural stem and progenitor cells in the brain from dividing; it hangs them up," Basu said. "It's the first time that a mosquito-borne virus has ever been shown to affect neural stem cells." The progressive infection in these cells ev
'/>"/>

Contact: Anirban Basu, Ph.D.
anirban@nbrc.ac.in
91-124-233-8922
Wiley-Blackwell
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. ESMO, Oxford Journals and the Japanese Society of Medical Oncology announce collaboration
2. STAAR Surgical to Purchase Canons Interest in Japanese Joint Venture
3. Chemo Drug Improves Stomach Cancer Survival for Japanese Patients
4. SNM/Nihon Medi-Physics sponsor new fellowship program for Japanese physicians
5. STAAR Surgical Completes $5M Debt Financing for Purchase of Japanese Joint Venture
6. Nihon LocalSoft Designs New Japanese Software for IRadimed Corporations Award-Winning MRidium MRI Infusion System
7. Seahorse Bioscience Enters into Agreement with Primetech Corporation to Bring XF Technology to Japanese Market
8. Health and Beauty Come Full Circle: Chado-En Brings Full Benefit of Japanese Green Tea to Spas
9. Geneticists at the American Museum of Natural History trace the evolution of St. Louis encephalitis
10. Virus Could Help Drive Obesity
11. Scientists detect presence of marburg virus in african fruit bats
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... Juvent Sports ( http://www.juventsports.com ) and David Leadbetter ... to bestow a Juvent Sports Achievement award upon an ... The award commemorated and congratulated McKitrick for her record ... her first amateur tournament in 1979 and most recently ...
(Date:1/22/2015)... January 22, 2015 For over 20 years, Dr. ... Oceanside and Vista area has treated just about every type ... injury circumstances. And for those same twenty-plus years, the team ... all those injuries with the best possible doctor. With ...
(Date:1/22/2015)... Yesterday, Senator Holly Mitchell (D-Los ... Olsen (R-Modesto) were honored by the California Healthcare ... biomedical science, medical device and pharmaceutical innovation in ... “2014 Life Sciences Champion” award from CHI President ...
(Date:1/22/2015)... WASHINGTON, DC (PRWEB) January 22, 2015 ... conditions in vulnerable communities and cause financial distress to ... report by analysts at Howard University’s Center on Race ... of dollars in economic activity, payday loans at the ...
(Date:1/22/2015)... released a new blog post presenting a list of vehicles that ... , Some types of vehicles cannot be covered under an ordinary ... to see if their vehicle qualifies for auto insurance coverage. ... cars that cannot be covered by a plan. Clients have little ...
Breaking Medicine News(10 mins):Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 3Health News:Industry Leading Chiropractor in Oceanside Joins the Doctors on Liens Network 2Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 2Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 3Health News:Howard University Spotlights the Economic Impact of Payday Lending in Southern States 2Health News:Some Vehicles Cannot Be Covered By An Auto Insurance Policy! 2
... support proteomic test as a predictor of overall survival ... on VeriStrat, a blood-based, proteomic test currently used for ... be presented by Christine Chung, MD, Assistant Professor of ... 1st at the 45th Annual Meeting of the American ...
... Medical Waste Processing PermitSUN VALLEY, Calif., May 14 ... Sun Valley, California, the owner and worldwide patent ... System(TM), today announced its latest medical waste processing ... on 2.7 acres at 2020 Montcalm Street in ...
... ImQuest Bio and Arisyn jointly presented important new results ... hepatitis C virus (HCV) replication, at the 13th ISVHLD meeting ... the ability of PG301029 to potently suppress the replication of ... of antiviral action through the selection of a replicon resistant ...
... storage system extends PreXion3D image scans to network ... ( www.Prexion.com ), a leader in ... availability of DataServer/PX, a DICOM-conformant, massive storage system ... that has accumulated over time through the use ...
... Genetics, Inc. (NYSE Amex: ILI ) today ... ended March 31, 2009."In the first quarter we met ... on a very important research collaboration with a biotech ... and obesity at two important scientific conferences, established a ...
... Griffin, group president, health plans, Medco Health Solutions, Inc. ... the Deutsche Bank 34th Annual Health Care Conference in ... InterContinental Boston, will begin at 8:50 a.m. EDT. ... to attend.The presentation may be heard live via a ...
Cached Medicine News:Health News:May 14, 2009: Biodesix Announces VeriStrat(R) Data in Head and Neck Cancer to be Presented at ASCO 2Health News:May 14, 2009: Biodesix Announces VeriStrat(R) Data in Head and Neck Cancer to be Presented at ASCO 3Health News:Back Home Again in Indiana 2Health News:ImQuest BioSciences and Arisyn Therapeutics Introduce Novel New HCV Therapeutic Agent at Hepatitis Conference 2Health News:PreXion Adds a Fast, High-Volume Data Storage and Archiving System for Use With Its PreXion3D CBCT X-ray System 2Health News:Interleukin Genetics Reports First Quarter 2009 Financial Results 2Health News:Interleukin Genetics Reports First Quarter 2009 Financial Results 3Health News:Interleukin Genetics Reports First Quarter 2009 Financial Results 4Health News:Interleukin Genetics Reports First Quarter 2009 Financial Results 5Health News:Interleukin Genetics Reports First Quarter 2009 Financial Results 6Health News:Medco to Present at the Deutsche Bank 34th Annual Health Care Conference 2
(Date:1/23/2015)... 23, 2015  Mallinckrodt plc (NYSE: MNK ) ... a share repurchase program. The open-ended authorization permits the ... plc ordinary shares. "Funding additional initiatives ... as we continue to pursue a range of focused ...
(Date:1/22/2015)... 2015  ViewRay™, a privately held medical device company, announced ... agreement with ITOCHU Corporation (Tokyo Stock Exchange TYO: 8001) ... treatment of cancer in Japan . ... first and only MRI-guided radiation therapy system that images ...
(Date:1/22/2015)... Jan. 22, 2015 /PRNewswire/ - Pivotal Therapeutics Inc. (OTCQX:PVTTF; CSE:PVO), ("Pivotal" ... on Omega-3 therapies for cardiovascular disease and overall health is ... accomplishments in 2014 and its outlook for 2015 from the ... Shareholders, We would like to take this opportunity ...
Breaking Medicine Technology:Mallinckrodt plc Announces Share Repurchase Program 2Mallinckrodt plc Announces Share Repurchase Program 3Mallinckrodt plc Announces Share Repurchase Program 4ITOCHU Named the Exclusive Distributor for ViewRay's MRI-Guided Radiation Therapy System in Japan 2Pivotal Therapeutics: Year in Review and CEO Update 2Pivotal Therapeutics: Year in Review and CEO Update 3Pivotal Therapeutics: Year in Review and CEO Update 4Pivotal Therapeutics: Year in Review and CEO Update 5Pivotal Therapeutics: Year in Review and CEO Update 6Pivotal Therapeutics: Year in Review and CEO Update 7
... SANTA MONICA, Calif., Feb. 16, 2012 GoodRx ... prescription drug price comparison technology that provides consumers with accurate ... both a website and free iphone app ... greatly between competing pharmacies, and find discounts, free coupons and ...
... 15, 2012 Halozyme Therapeutics, Inc. (NASDAQ: HALO ... of 7,820,000 shares of its common stock, including 1,020,000 shares ... previously granted to the underwriter. All of the shares were ... $10.61 per share. The proceeds to Halozyme from this offering ...
Cached Medicine Technology:GoodRx™ Brings Price Transparency to Prescription Drugs 2GoodRx™ Brings Price Transparency to Prescription Drugs 3GoodRx™ Brings Price Transparency to Prescription Drugs 4Halozyme Announces Exercise in Full of Over-Allotment Option and Completion of Public Offering of Stock 2Halozyme Announces Exercise in Full of Over-Allotment Option and Completion of Public Offering of Stock 3
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: