Navigation Links
Japanese Researchers Develop New Smallpox Vaccine

No serious side effects are found in latest test, study reports,,

TUESDAY, March 10 (HealthDay News) -- A third-generation tissue-cultured smallpox vaccine shows promise, Japanese researchers report.

"The threat of smallpox bioterrorism has prompted reconsideration of the need for smallpox vaccination," the researchers noted. "Serious events associated with first-generation vaccines #133; have raised obstacles to vaccination campaigns in the United States."

Second-generation vaccines also cause a high rate of serious side effects, they said.

"Developing a vaccine that is safer than first-generation vaccines yet highly immunogenic [producing immunity or an immune response] is crucial to constructing a prevention plan in the event of bioterrorist attack," they added.

The researchers studied the clinical and immunological responses to the LC16m8 vaccine in 1,692 adults who had previously been vaccinated against smallpox and 1,529 adults who had not been vaccinated. LC16m8 is a live, attenuated (reduced in strength) vaccine.

Participants were examined 10 to 14 days after being vaccinated. The researchers found that antibodies developed in about 90 percent of those who had not been previously vaccinated, and an effective booster response occurred in 60 percent of those who had previously been vaccinated. None of the participants suffered serious side effects.

The study "offers supported evidence for the safety of LC16m8 vaccine in adults," wrote Dr. Tomoya Saito, of Keio University in Tokyo, and his colleagues."LC16m8 vaccine appears to be a viable alternative to first-, second- and other third-generation vaccines in a smallpox [bioterrorism] preparedness program."

The study appears in the March 11 issue of the Journal of the American Medical Association.

More information

The U.S. Centers for Disease Control and Prevention has more about smallpox.

-- Robert Preidt

SOURCE: Journal of the American Medical Association, news release, March 10, 2009

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. ESMO, Oxford Journals and the Japanese Society of Medical Oncology announce collaboration
2. STAAR Surgical to Purchase Canons Interest in Japanese Joint Venture
3. Chemo Drug Improves Stomach Cancer Survival for Japanese Patients
4. SNM/Nihon Medi-Physics sponsor new fellowship program for Japanese physicians
5. STAAR Surgical Completes $5M Debt Financing for Purchase of Japanese Joint Venture
6. Nihon LocalSoft Designs New Japanese Software for IRadimed Corporations Award-Winning MRidium MRI Infusion System
7. Seahorse Bioscience Enters into Agreement with Primetech Corporation to Bring XF Technology to Japanese Market
8. Health and Beauty Come Full Circle: Chado-En Brings Full Benefit of Japanese Green Tea to Spas
9. Japanese encephalitis virus causes double trouble to brain
10. Fondness for Fish Keeps Japanese Hearts Healthy
11. First Implant of DuraHeart(TM) Left Ventricular Assist System (LVAS) in Japanese Clinical Trial
Post Your Comments:
Related Image:
Japanese Researchers Develop New Smallpox Vaccine
(Date:11/27/2015)... (PRWEB) , ... November 27, 2015 , ... ... failing. Secura Consultants has prided itself for not only fulfilling the needs of ... protection solutions at an affordable price and providing top-tier customer service. However, there's ...
(Date:11/27/2015)... Rosa, CA (PRWEB) , ... November 27, 2015 , ... ... Northern California Medical Associates, Inc. and Dr. Tucker Bierbaum with Emergency Medicine at ... meeting. They observed that both STEMI and Sepsis conditions present in similar ways and ...
(Date:11/26/2015)... , ... November 26, 2015 , ... Inevitably when people ... customers choose to buy during the Black Friday and Cyber Monday massage ... need to search the Internet high and low to find the best massage chair ...
(Date:11/26/2015)... ... November 26, 2015 , ... Jobs in hospital medical laboratories and in the ... healthcare staffing agency Aureus Medical Group . These fields, as well ... those searching for healthcare jobs through the company’s website, , The ...
(Date:11/26/2015)... ... November 26, 2015 , ... ... and wellness consultation, has collaborated with Women’s Web – an online resource ... on topics on mental and emotional well-being relationship, life balance, stress, professional ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... UTRECHT, the Netherlands , November 26, 2015 /PRNewswire/ ...   A new combination approach blends immunotherapy ... --> A new combination approach blends immunotherapy with ... A new combination approach blends immunotherapy with ... the Netherlands has found that immunotherapy ...
(Date:11/26/2015)... --> --> ... find optimal contrast weighting of MRI for patients with ... a research agreement with SyntheticMR in order to use SyMRI ... is possible to generate multiple contrast images from a single ... left, thus making it possible to both fine tune images ...
(Date:11/26/2015)... FRANCISCO , November 26, 2015 ... billion by 2022, according to a new report by Grand ... Chronic Kidney Disease (CKD) which demands kidney transplantation is expected ... and cost effective substitute for organ transplantation. --> ... billion by 2022, according to a new report by Grand ...
Breaking Medicine Technology: