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January/February 2012 Annals of Family Medicine
Date:1/9/2012

>Comparing first-void with midstream urine sampling, researchers find similar diagnostic accuracy for Chlamydia trachomatis testing. Of 100 patients with a first-void specimen positive for C trachomatis, 96 (96 percent) also had a positive midstream specimen. The authors conclude the use of newer nucleic acid amplification techniques makes the timing of specimen collection not as important for C trachomatis testing as previously thought. The ability to test for both C trachomatis and urinary tract infection (traditionally diagnosed using a midstream urine specimen) on a single midstream urine specimen could greatly aid clinical practice as urinary tract infection is an extremely common complaint in primary care and using one sample avoids the practical difficulty of collecting (or being unable to collect) further specimens from patients with uncertain diagnosis or reporting symptoms of both infections.

Chlamydia trachomatis Testing Sensitivity in Midstream Compared With First-Void Urine Specimens

By Derelie (Dee) Mangin, MB, ChB, DPH

University of Otago, Christchurch, New Zealand

Creating a Learning Health Care System, Possibilities and Market Limitations

Highlighting both the challenges and opportunities for using existing electronic clinical data from dispersed primary care practices to facilitate large-scale clinical research, the authors examine options and evaluate a functional software prototype for facilitating research within community practice settings. The Electronic Primary Care Research Network project was one of 12 funded by the National Institutes of Health with aim of developing clinical research. To fully realize the vision of a true learning health care system, the authors call for the creation of an open market for e-health applications. Such a system, they assert, can be achieved only through open collaboration between the various stakeholders from clinicians to vendors with the goal of creating a single shared ar
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Contact: Angela Sharma
asharma@aafp.org
913-269-2269
American Academy of Family Physicians
Source:Eurekalert

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