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Jacobs-Wagner named Howard Hughes Investigator
Date:5/27/2008

n animal cells. She has shown that knocking out intermediate filaments, which have been linked to some 30 human diseases, can change the shape of the bacteria.

Her lab has also developed techniques to track the location of proteins at different points of the cell cycle. The work has enabled her lab to show that the location of a protein at different times can have significant impact on a cells function. These mechanisms help regulate how dividing cells with same genetic make-up can become morphologically and physiologically different.

Jacobs-Wagner might never have donned a lab white coat if a shoulder injury had not ended her badminton career. It was then the former Belgian national team member turned to her second loves, molecular biology and biochemistry.

Those interests led her to study of how bacteria became resistant to antibiotics and instilled in her a passion for seemingly simple organisms. She received her bachelors and masters degrees in biochemistry at the University of Lige, in Belgium and her doctorate at Lige and the Karolinska Institute in Sweden. She joined Yale as an assistant professor in 2001.

In the past two decades HHMI has made investments of more than $8.3 billion for the support, training, and education of the nations most creative and promising scientists. The Institute commits almost $700 million a year for research and distributes $80 million in grant support for science education.


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Contact: Bill Hathaway
william.hathaway@yale.edu
203-432-1322
Yale University
Source:Eurekalert

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