Navigation Links
JNCI news brief: High serum insulin levels and risk of prostate cancer
Date:8/21/2009

Elevated insulin levels in the normal range appear to be associated with an increased risk of prostate cancer, according to a new study published online August 21 in the Journal of the National Cancer Institute.

Insulin-like growth factors appear to be involved in the development of prostate cancer, but the relationship between circulating insulin levels and prostate cancer risk has been unclear.

Demetrius Albanes, M.D., of the Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics at the National Cancer Institute in Bethesda, Md., and colleagues investigated the relationship of the level of serum insulin and glucose, as well as surrogate indices of insulin resistance, to the development of prostate cancer. Researchers conducted a prospective casecohort study nested within a cancer prevention study of Finnish men (100 case subjects with prostate cancer and 400 non-case subjects without prostate cancer). Levels of insulin were determined in fasting serum that had been collected 5-12 years before diagnosis of prostate cancer.

The authors found that when subjects in the second through fourth quartiles of serum insulin concentration were compared with those in the first or lowest quartile, higher insulin levels within the normal range were associated with statistically significantly increased risk of prostate cancer. Risk was not associated with serum glucose concentration.

"These findings support a role for higher circulating insulin in prostate carcinogenesis, especially in early-stage disease," the authors write.


'/>"/>

Contact: Steve Graff
jncimedia@oxfordjournals.org
301-841-1285
Journal of the National Cancer Institute
Source:Eurekalert

Page: 1

Related medicine news :

1. In brief: New prognostic indicator for patients with IPF
2. JNCI news brief: Improving the biomarker pipeline for early cancer detection
3. JNCI news brief: Hepatitis B virus mutations may predict risk of liver cancer
4. JNCI news brief: Breast cancer hormone receptor status and risk of a second primary tumor
5. JNCI news brief: Antibody linked to chemotherapy drug inhibits ovarian cancer in lab
6. Nourishment Is Essential to a Youthful Appearance. Time to Feed Your Face with Serum_G
7. Data Show Vaprisol(R) Is Effective & Safe in Promptly Increasing Serum Sodium Levels in Patients With Euvolemic or Hypervolemic Hyponatremia
8. Panacea Pharmaceuticals Announces the Availability of CC Detect(SM), a Serum-Based Diagnostic Test for Colon Cancer
9. Serum carcinoembryonic antigen level can reflect adrenal adenoma
10. What are the essential characteristics of serum PG in Chinese?
11. Americas StriVectin the Only Great Serum for Mature, Aging Complexions, Says Leading British Newspaper
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/23/2017)... Colorado (PRWEB) , ... February 23, 2017 , ... ... Magazine, an exciting, new, interactive publication where generations converge and explore the world ... expand their worldview, Dialog Magazine enables readers to gain understanding, increase empathy, and ...
(Date:2/23/2017)... ... February 23, 2017 , ... Current Meditation , a ... franchising throughout the U.S. starting this spring. Current Meditation focuses on “meditation for ... mainstream. Current Meditation will be the first meditation concept in the U.S. offering ...
(Date:2/23/2017)... Lincoln, RI (PRWEB) , ... February 23, 2017 ... ... announced today a new partnership with the Rhode Island Consortium for Autism Research ... provide an opportunity for children with autism spectrum disorder (ASD) to see films ...
(Date:2/23/2017)... ... , ... CALNOC, the nation’s first and only nursing quality indicators database today ... Value and Collaboration – in Seattle, WA on October 23, 2017. , Dr. Gary ... in Seattle since 2000. In addition to his role at Virginia Mason, Dr. Kaplan ...
(Date:2/23/2017)... (PRWEB) , ... February 23, 2017 , ... Curemark, LLC ... safety and efficacy of CM-AT in children aged 3-8 with Autism, is now enrolling ... sites already enrolling children across the United States. , “There are currently no ...
Breaking Medicine News(10 mins):
(Date:2/23/2017)... , Feb 23, 2017 Research and Markets ... Strategies - 2016" report to their offering. ... The latest research Menopause Drugs Price Analysis and ... Menopause market. The research answers the following questions: ... clinical attributes? How are they positioned in the Global Menopause market? ...
(Date:2/23/2017)... Feb. 23, 2017 AcelRx Pharmaceuticals, Inc. ... the development and commercialization of innovative therapies for ... it will release fourth quarter and yearly financial ... 2017. AcelRx management will host an investment-community conference ... Pacific Time) on March 2 nd 2017 ...
(Date:2/23/2017)... Research and Markets has announced the addition of the ... report to their offering. ... The Global Endoscopy Market is poised to grow ... reach approximately $47.6 billion by 2025. This industry ... segments on global as well as regional levels presented in the ...
Breaking Medicine Technology: