Navigation Links
JNCI news brief: Hepatitis B virus mutations may predict risk of liver cancer
Date:7/2/2009

Certain mutations in the DNA of the hepatitis B virus (HBV) are associated with the development of liver cancer and may help predict which patients with HBV infections are at increased risk of the disease, according to a large meta-analysis in the Journal of the National Cancer Institute, published online July 2.

HBV infection is a known cause of hepatocellular carcinoma (HCC), the most common form of liver cancer. Previous studies have looked at whether patients with specific mutations in the viral DNA may be at increased risk of developing the cancer, but most of the studies were small and they produced conflicting results.

This meta-analysis, conducted by Guangwen Cao, M.D., Ph.D., of the Second Military Medical University in Shanghai and colleagues, included 43 studies with a total of 11,582 HBV-infected participants, of whom 2,801 had HCC. The researchers found that certain mutations were associated with development of HCC and more prevalent as chronic HBV infection progressed from the asymptomatic state to liver cirrhosis or HCC.

"Frequent examination of patients with chronic HBV infections for the presence of these mutations may be useful for identifying which patients require preventive antiviral treatment and for the prediction of HCC," the authors write.


'/>"/>

Contact: Steve Graff
jncimedia@oxfordjournals.org
301-841-1285
Journal of the National Cancer Institute
Source:Eurekalert

Page: 1

Related medicine news :

1. JNCI news brief: Improving the biomarker pipeline for early cancer detection
2. In brief: New prognostic indicator for patients with IPF
3. Hepatitis C Virus Market Will Expand Dramatically From $2 Billion in 2008 to Nearly $7.7 Billion in 2013
4. Good news for some hard-to-treat hepatitis C patients
5. Aethlon Medical Releases Shareholder Letter to Discuss the Treatment of Hepatitis-C Virus (HCV)
6. Pharmasset Initiates Phase 1b Multiple Ascending Dose Clinical Trial of PSI-7851 in Chronic Hepatitis C Patients
7. NEJM study points to new era in hepatitis C treatment
8. Resource for Those Living with Hepatitis C Announces Website Redesign
9. AUDIO from Medialink, Bayer Healthcare and Onyx Pharmaceuticals: Facts About Hepatitis
10. New treatment option for patients with chronic hepatitis C
11. National Viral Hepatitis Roundtable Observes World Hepatitis Day and Calls for Increased Federal Action
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/20/2017)... , ... January 20, 2017 , ... “The Land of ... attention to the issue of world hunger, and shares the simple and achievable answer. ... devoted husband and member of the Fairview Missionary Church in Angola, Indiana where he ...
(Date:1/19/2017)... ... ... Today, the Centers for Medicare & Medicaid Services (CMS) announced over 359,000 clinicians ... Clinicians who participate in APMs are paid for the quality of care they give ... build a system that delivers better care and one in which clinicians work together ...
(Date:1/19/2017)... ... 19, 2017 , ... Next week after January 20th, the fear for many ... that circumvent health needs of over 30 million. Many interviews with Dr. Carol Francis ... government public servants were suppose to prioritize. Interviews provided below. , Among ...
(Date:1/19/2017)... LINCOLN, R.I. (PRWEB) , ... January 19, 2017 , ... With the cold weather here, ... sidewalks. , Snow blowers are efficient when clearing large amounts of snow, but they can ... tips from the U.S. Consumer Product Safety Commission for the proper use of snow blowers:, ...
(Date:1/19/2017)... ... January 19, 2017 , ... LabRoots , the ... around the world, announces the launch of its newly redesigned website. The sleek ... research breakthroughs and trending news, vital information on upcoming virtual events and webinars, ...
Breaking Medicine News(10 mins):
(Date:1/20/2017)... 2017 Entscheidung fällt ... Die internationale humanitäre Stadt soll um knapp ... Seine Hoheit Scheich Muhammad bin ... Herrscher von Dubai , hat den ... (International Humanitarian City IHC) zu verdreifachen, um den Betrieb ...
(Date:1/19/2017)... 19, 2017 The Global Therapy Partnering Terms ... to partnering deals and agreements entered into by the ... deals - Top deals by value - Deals listed ... type The report provides understanding and access to ... world,s leading healthcare companies. The report provides an ...
(Date:1/19/2017)... 19, 2017 Many patients don,t realize that ... when a pharmacy just a few blocks away charges ... this problem Medicationdiscountcard.com has created a price ... how much their medication will cost at most nearby ... Medicationdiscountcard.com takes all of ...
Breaking Medicine Technology: