Navigation Links
JNCI April 28 tip sheet
Date:4/28/2009

Designing a Randomized Controlled Trial for Physical Activity, Weight Control, and Breast Cancer Risk

Researchers describe the rationale and a possible design for randomized controlled trials that test the impact of physical activity and weight control on breast cancer risk.

There are substantial observational data suggesting that regular physical activity and maintaining a healthy weight are associated with a reduction in breast cancer risk: however, it is unclear whether the apparent association is due to unknown confounding factors. An important way to determine if the lifestyle choices have a causal relationship with breast cancer risk is to test the hypothesis in the setting of a randomized controlled trial.

In the current commentary, Rachel Ballard-Barbash, M.D., of the National Cancer Institute in Bethesda, Md., and colleagues present designs for two trials, one in women who are at high risk of disease and one in breast cancer survivors. The interventions in the two trials could be the same; the goal for the weight control intervention would be a 10% weight loss for women with a body mass index above 25 kg/m2 at enrollment and avoidance of weight gain for those below 25 kg/m2. The goal for the physical activity intervention would be to achieve and maintain 150-220 minutes of physical activity per week.

"In conclusion, given the magnitude of the public health problem and the amount of accumulated evidence in support for this next level of scientific evidence, it is now appropriate to explore in detail the feasibility and timing of a large randomized trial to assess the effects of physical activity and weight control on breast cancer risk and/or prognosisand the trade-offs in moving toward the prevention vs the survival trial," the authors write.

Contact: NCI press office, ncipressofficers@mail.nih.gov, 301-496-6641


Clusterin A
'/>"/>

Contact: Steve Graff
jncimedia@oxfordjournals.org
301-841-1285
Journal of the National Cancer Institute
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. U.S. Census Bureau Daily Feature for April 28
2. Donate Life California to Hold Press Conference Commemorating Donation Heroes Tuesday, April 28, 10:00 a.m., State Capitol
3. Donate Life California to Hold Press Conference on Organ Donation Education, April 28, 1:30 p.m., on State Capitol West Steps
4. Kaiser Permanente Continues to Spread Health With New Ads Debuting in April
5. Omnicell to Release First Quarter 2009 Earnings Results on April 30
6. Largest Organ and Tissue Donation Event in U.S.: Seventh Annual Donate Life Run/Walk & Family Festival, Sat., April 25 at Cal State Fullerton
7. Seniors Invited to Learn About Fraud Prevention at SCAN Connections Resource Center on April 28
8. Light of Hope: Help for Children with Autism Ground-Breaking Internet Television Event on April 24 to April 26 Co-Sponsored by Internet Software Leaders
9. Palomar Medical Technologies to Host First Quarter 2009 Financial Results Conference Call and Webcast on April 30, 2009
10. Turn the Corner Foundation Rings in Lyme Disease Awareness Month Early at NYSE on April 23, 2009
11. YWCA USA to Observe World YWCA Day - April 24
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/25/2014)... December 25, 2014 BambooFlooringChina.com sells many ... quality bamboo flooring. Today, the company announces big ... many styles and colors. , BambooFlooringChina.com is the world’s ... the promotion is valid until Jan. 20, 2015. , ... and woven with a natural thread. All the bamboo ...
(Date:12/25/2014)... -- The risk of burns from fires and cooking ... be extra cautious, an expert says. "Between Thanksgiving ... in patients coming in with burns," said Dr. Steven ... Burn Center of Stony Brook University Hospital in New ... but if not careful, could quickly turn tragic," Sandoval ...
(Date:12/25/2014)... York (PRWEB) December 25, 2014 Thousands ... to move forward in a number of multidistrict litigations ... West Virginia, Bernstein Liebhard LLP reports. According to an ... scheduled to convene a Joint Status Conference in all ... a.m. Parties have been directed to submit a proposed ...
(Date:12/25/2014)... (PRWEB) December 25, 2014 Parker & ... outstanding customer service and affordable quality regarding heating, cooling ... announces recognition in 2014 by the “Queen of Clean” ... has earned an impressive reputation over the years for ... a wide range of contractor services for both homeowners ...
(Date:12/24/2014)... Recently, iFitDress.com, a famous dress manufacturer and retailer, has ... All these items are brand new; they are made by ... with the new range of high quality prom gowns. A ... designs are made according to the latest trends. For years, ... from the company is handpicked by skilled tailors. , In ...
Breaking Medicine News(10 mins):Health News:Various Styles of Bamboo Mats in Many Colors from BambooFlooringChina.com 2Health News:Don't Let Burns Mar Your Holidays 2Health News:Federal Court Overseeing Thousands of Transvaginal Mesh Lawsuits Set to Convene Joint Status Conference for All Litigations, Bernstein Liebhard LLP Reports 2Health News:Federal Court Overseeing Thousands of Transvaginal Mesh Lawsuits Set to Convene Joint Status Conference for All Litigations, Bernstein Liebhard LLP Reports 3Health News:Federal Court Overseeing Thousands of Transvaginal Mesh Lawsuits Set to Convene Joint Status Conference for All Litigations, Bernstein Liebhard LLP Reports 4Health News:Parker & Sons Announces Recognition In 2014 By The “Queen Of Clean” For Impressive Contractor Services In Arizona 2Health News:Parker & Sons Announces Recognition In 2014 By The “Queen Of Clean” For Impressive Contractor Services In Arizona 3Health News:Many Prom Dresses under 150 from Well-known Dress Manufacturer iFitDress.com 2
... and relaxation exercises can help cut the pain, experts say , ... run away from an injection, so it,s no surprise that children ... it,s time for flu shots this year. , "The good ... to positively impact their child,s experience when getting a needlestick -- ...
... , GAINESVILLE, Fla., Oct. 18 Previously e cigarettes ... product for themselves. However, Teresa Peach, an online sales ... wishing to purchase the product for their loved ones ... they wish to buy the electronic cigarette starter kit ...
... Epileptic seizures are the most dramatic and prominent aspect ... person abruptly stops a long-term or chronic drinking habit. ... into brain cells via voltage-gated calcium channels plays an ... because blocking this flow suppresses these seizures. But do ...
... , FRESNO, Calif., Oct. 17 Nearly 40 local organizations ... the Lowell Neighborhood Resource Center to host the Celebrate ... at Lowell Elementary School from 10:00 a.m. to 2:00 p.m. ... rise to 14.6 percent, the need for local health and ...
... Veterans with disorder more likely to die within a ... 17 (HealthDay News) -- Veterans with post-traumatic stress disorder ... if the surgery is performed years after they have ... Researchers analyzed data on 1,792 male veterans who had ...
... , NASDAQ: CRME ... (NASDAQ: CRME / TSX: COM) ("Cardiome" or the "Company") ... to purchase for cancellation up to US$27.5 million of its common ... October 13, 2009. Cardiome has accepted 6,470,588 of its common shares ...
Cached Medicine News:Health News:Online Sales of E Cigarettes Expected to Rise Over the Holidays 2Health News:Anthem Blue Cross Teams with Lowell Neighborhood Resource Center to Address Health and Wellness Needs in Fresno 2Health News:Post-Traumatic Stress May Raise Death Risks 2Health News:Cardiome Pharma Corp. Announces Final Results of Tender Offer 2Health News:Cardiome Pharma Corp. Announces Final Results of Tender Offer 3Health News:Cardiome Pharma Corp. Announces Final Results of Tender Offer 4
(Date:12/24/2014)...  Medical Science Liaisons play a large role in ... medical device industry and key stakeholders, the role of ... as the device industry relies on them to build ... benchmarking firm, Best Practices, LLC, one area where Medical ... by harnessing new technology to enable education. Online conferences ...
(Date:12/22/2014)... , Dec. 22, 2014 Apnea Sciences ... corporate offices in Aliso Viejo , ... due to the tremendous growth and worldwide expansion, a ... of patented SnoreRx, the anti snore cure have exceeded ... said, "We are now in 23 countries and ...
(Date:12/22/2014)... Research and Markets ( http://www.researchandmarkets.com/research/hmlfbq/investment ... "Investment Analysis of the US Medical Device Sector ... http://photos.prnewswire.com/prnh/20130307/600769 This ... sector identifies the key trends and rationale for ... mergers and acquisitions. The study will ...
Breaking Medicine Technology:Role of Medical Science Liaisons Evolving in Medical Device Sector 2Investment Analysis of the US Medical Device Sector 2
... 18, 2011 Bexion Pharmaceuticals was named the Biotech ... program sponsored by the Cincinnati Business Courier, the Cincinnati ... outstanding innovation and the companies and people who have ... for the regional Tri-State (Ohio/Kentucky/Indiana) economic engine. ...
... Md., April 18, 2011 Science, public ... Food and Drug Administration. I nformation in this document ... items are current as of April 18, 2011. ... & Notes does not contain any regulatory or enforcement actions ...
Cached Medicine Technology:Bexion Pharmaceuticals Receives Outstanding Biotech Innovation Award 2FDA News & Notes - Week of April 18, 2011 2
This fixed-volume digital micropipet is used to accurately measure and transfer 50 microliters of solution....
50L...
... Focus from Thermo Labsystems was ... with uncompromising performance. The ... a custom fit for different ... tip cones allow easier and ...
... Eppendorf Reference Series 2000 Pipette is a ... a compact and robust design, and superior ... used to operate the measuring stroke and ... Product features:Eppendorf "pipette/tip" system ensures utmost accuracy ...
Medicine Products: