Navigation Links
JDRF to establish an autoimmunity center at University of Colorado Denver
Date:1/28/2008

AURORA, Colo. (Jan. 28, 2008) Researchers at the Barbara Davis Center for Childhood Diabetes at the University of Colorado Denver have new resources in their fight against type 1 diabetes: The Juvenile Diabetes Research Foundation has approved funding for the establishment of a JDRF Autoimmunity Center at the Barbara Davis Center for Childhood Diabetes, only the seventh in the nation. The Autoimmunity Center will receive approximately $1 million a year over the next five years to further fund research leading to a cure for type 1 diabetes.

The goal of this partnership is to utilize the Barbara Davis Centers resources in collaboration with JDRFs to create an Autoimmunity Center to develop therapies specifically aimed at immunoprevention of type 1 diabetes. Type 1 diabetes is an autoimmune disease that develops when the bodys immune system mistakenly targets the beta cells of the pancreas, the cells that make insulin.

The JDRF Center will bring together faculty with complementary expertise and knowledge to advance the understanding of pathogenesis diabetes in animals and humans as well as allow us to implement trials in human subjects based on the results, said John Hutton, PhD, research director at the Barbara Davis Center for Childhood Diabetes at the University of Colorado Denver and principal investigator on the grant. We have learned an immense amount in the past 20 years about the causes of the disease and have sophisticated genetic and immunological assays to predict it -- the challenge is how to translate this knowledge into effective therapies, particularly those aimed at circumventing the progression of autoimmunity to clinical disease. The JDRF Center will help us tremendously with addressing this challenge.

We are delighted to establish the JDRF Autoimmunity Center at the Barbara Davis Center, said Teodora Staeva, Ph.D. Program Director, Autoimmunology, at JDRF. This JDRF Center will focus on developing novel antigen-specific approaches to predict, prevent, and possibly reverse type 1 diabetes.

The JDRF Center brings together a team of basic scientists and clinical researchers, and includes Dr. Hutton, along with George Eisenbarth, MD, PhD; Peter Gottlieb, MD; Howard Davidson, PhD; and Danny Zipris. The Barbara Davis Center for Childhood Diabetes will be the administrative hub of this JDRF Autoimmunity Center.

Two of the three main research projects will investigate the new autoantigen, ZnT8 -- a recently discovered fourth antigenic specificity recognized by an antibody in human blood that will help more accurately predict who is predisposed to type 1 diabetes. The initial research and discovery was led by Dr. Hutton and his research team at the Barbara Davis Center, and supported by the Childhood Diabetes Foundation in Denver.

A clinical trial will be conducted in children with extreme risk of developing type 1 diabetes using an insulin-based vaccination procedure aimed at preventing the occurrence of autoimmunity that inevitably leads to diabetes. A second trial is planned in the future based on ZnT8 and will develop similar prevention strategies.


'/>"/>

Contact: Leslie Schwartz
lschwartz@jdrf.org
212-479-7553
Juvenile Diabetes Research Foundation International
Source:Eurekalert

Related medicine news :

1. Bayer Establishes US Special Access Program for Leukine(R) While Replacing Current Liquid Formulation
2. Antibody Engineering Company f-star Appoints Three Pioneers in Antibody Engineering and Development to its Newly Established Scientific Advisory Board
3. MM2 Group Establishes New Venture for Sofgel Manufacture in China
4. Sens. Kerry, Boxer and Feinstein call on FDA to Establish Maximum Level for Lead in Lipstick
5. CIG Corp. Establishes a Medical Advisory Board
6. NxStage Medical Establishes $50 Million Credit Facility with a Group of Lenders Led by Merrill Lynch Capital
7. Parascript Enters Medical Imaging Breast Cancer Detection Market With Established Image Analysis Technology
8. Nunez Health Reform Bill Establishes Mandatory Purchase Without Linking to Subsidies for Middle Class and Poor
9. Nastech to Establish Subsidiary, MDRNA, Inc., as an Independent Company to Focus on the Development of RNA-Based Therapeutics
10. Sentry Telecare Establishes Partnering Program to Market Telephone Check-in and Personal Emergency Response Service
11. Conference on Elephant Tuberculosis Research Establishes Action Plan at International Symposium on Elephant Conservation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2017)... ... June 23, 2017 , ... ... in Newburgh, New York, has recently begun offering three new minimally invasive procedures ... best cutting-edge procedures and reducing downtime, Dr. Rubinstein is excited to bring microneedling, ...
(Date:6/23/2017)... ... June 23, 2017 , ... The Aesthetic Channel has ... Dr. Talei has come up with a proprietary technique that he calls the ... that have dropped. For all ages, patients can expect to look refreshed, rejuvenated, and ...
(Date:6/23/2017)... ... 2017 , ... MD Now Urgent Care opened its newest location ... and marks the urgent care center's eighth location in Miami-Dade county. , The center's ... mall. The new clinic offers a wide array of services to patients ...
(Date:6/23/2017)... ... June 23, 2017 , ... Ulster University, Magee Campus ... from 9 am to 3 pm to present to graduate students exciting new and ... an original curriculum project led by The Health Improvement Service of the Western Health ...
(Date:6/23/2017)... ... June 23, 2017 , ... ... financial planning to families and business owners in North Central West Virginia, is ... provide services to differently abled residents in the region. , The Stepping Stones ...
Breaking Medicine News(10 mins):
(Date:6/20/2017)... , June 19, 2017  Hill-Rom Holdings, Inc. (NYSE: ... call and webcast on Friday, July 28, 2017, beginning at ... Call Audio Only Dial-in information: To participate in the conference ... dial into the call at least 10 minutes prior to ... is 34090339.  Webcast: ...
(Date:6/16/2017)... June 16, 2017  Exactly 50 years ago today, the ... later became known as the San Francisco "Summer of Love."  ... unveiling two radical innovations in strategic market research portals that ... marks the beginning of Northern Light,s "Summer of Love (For ... ...
(Date:6/14/2017)... , June 14, 2017  In 2016, Embodied ... Startups pitch competition and came away with $25,000 ... is described by Forbes as "entering the life of ... Association as teaching "empathy to medical professionals in an ... was recently named a finalist for the Department of ...
Breaking Medicine Technology: