Navigation Links
JCI table of contents: Nov. 8, 2007
Date:11/8/2007

.the-jci.org/article.php?id=32994">https://www.the-jci.org/article.php?id=32994


MYCOLOGY: Working together: C. albicans, epithelial cells, and PMNs control oral thrush

New data generated by Martin Schaller and colleagues at Eberhard Karls University Tbingen, Germany, using an in vitro epithelial model of oral thrush, have provided new insight into how infection with the fungus Candida albicans, the most common cause of oral thrush, might be controlled in the mouth.

In the study, immune cells known as PMNs were shown to protect oral reconstituted human epithelium from invasion by C. albicans and from cell injury. However, PMN-mediated protection was not provided directly, rather it was provided indirectly by the PMNs inducing the upregulation of a protein known as TLR4 in the epithelium. Further analysis revealed C. albicans induced epithelial cells to express soluble factors that attract and activate PMNs and that the soluble factor TNF-alpha had an important role in initiating PMN-induced epithelial cell upregulation of TLR4 expression. The authors therefore concluded that oral thrush is controlled by three-way communication between C. albicans, the epithelium, and PMNs.

TITLE: Human epithelial cells establish direct antifungal defense through TLR4-mediated signaling

AUTHOR CONTACT:
Martin Schaller
Eberhard Karls University of Tbingen, Tbingen, Germany.
Phone: 49-7071-29-84555; Fax: 49-7071-29-5113; E-mail: Martin.Schaller@med.uni-tuebingen.de.

View the PDF of this article at: https://www.the-jci.org/article.php?id=28115


CARDIOVASCULAR DISEASE: Two heads are better than one: ABCA1 and ABCG1 combine to enable HDL to protect us from cardiovascular disease

Individuals with an imbalance in the amount of cholesterol associated wit
'/>"/>

Contact: Karen Honey
press_releases@the-jci.org
215-573-1850
Journal of Clinical Investigation
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8 9

Related medicine news :

1. Ranbaxy Receives Tentative Approval to Manufacture and Market Galantamine Tablets on an Exclusive Basis
2. Schering-Plough/Merck Pharmaceuticals Announce FDA Filing Acceptance of New Drug Application for Loratadine/Montelukast Tablet
3. JCI table of contents: Sept. 4, 2007
4. FDA Seeks to Regulate Complementary and Alternative Medicine; Products Such as Vegetable Juice Could Be Restricted for Medical Use
5. Actavis Launches Carvedilol Tablets in the U.S.
6. Mylan Announces Final FDA Approval for Carvedilol Tablets
7. Ranbaxy Gains Approval to Manufacture and Market Carvedilol Tablets in the U.S. Market
8. Actavis Launches Amlodipine Tablets in the U.S.
9. Implantable device designed to detect, stop seizures under study at MCG
10. Stevens Health, Technology and Society roundtable: Sept. 19
11. Fruity vegetables and fish reduce asthma and allergies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... 22, 2015 The federal court overseeing thousands ... District Court, Southern District of West Virginia has upheld a ... proceeding’s first bellwether trial. In an Order dated January 21st, ... after finding that C.R. Bard had not proven a miscarriage ...
(Date:1/22/2015)... Autocarinsurancebest.com has released a new blog post ... insurance policy . , Auto insurance quotes help many ... no longer necessary to call an agent or visit an ... on a single website: http://autocarinsurancebest.com/ . , Every business ...
(Date:1/22/2015)... York, NY (PRWEB) January 22, 2015 ... College of Sports Medicine flagship journal Medicine & ... with L-Citrulline before exercise may help reduce gastrointestinal ... exercise. 1 , Participants in the double-blind, ...
(Date:1/22/2015)... Four years since the release of their debut recording Love is ... Avasa & Matthew Love – the duo are pleased to announce ... White Swan Records on February 24, 2015. , THE ROAD offers ... to all of us to walk out of the mire of ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 JJsHouse.com is a ... dresses. Today, the business announces its latest collection of ... , “The most important issue is the wedding dress on ... thing in a woman’s life. Every bride wants to find ...
Breaking Medicine News(10 mins):Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 2Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 3Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 4Health News:Commercial Auto Insurance Provides Several Important Features! 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 2Health News:THE ROAD by Avasa & Matthew Love -- A New Album 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 4Health News:Find The Most Suitable Wedding Dress At JJsHouse.com 2
... HOUSTON and OTTAWA, Canada, March 3 ,InterACTIVE ... Nutrition,Inc. (OTC Bulletin Board: NTNI) http://www.naturalnutritioninc.com ... Iraq. Natural Nutrition,s Ottawa based,manufacturing facility, InterACTIVE ... nutritional demands of health conscious consumers in ...
... is an example of another,news article, in a respected ... who clinically need it is a good idea., ... it,s disgusting,to see this argument being presented by ,credible, ... a respected news outlet.), This time, they,re* going ...
... Health, Inc.,provider of secure health information technology ... to provide its electronic health record,solutions and ... information,network called the Tennessee Information Network or ... with the State of Tennessee began with ...
... New portable UV-C Light Sterilizer kills 99 percent of ... Uncomfortable using a public,restroom? Don,t want to touch the ... in the airplane?, (Photo: http://www.newscom.com/cgi-bin/prnh/20080303/CLM086 ), ... from Mark Feldstein & Associates, inc., a,Product Development Company ...
... ... the Hamm Brothers, Chellsie,Memmel and Lauryn Williams; Viewers Introduced to Families Behind Athletes, ... ... NBC,Olympics and iVillage today launched The Family Room presented by Johnson &,Johnson, a ...
... population-based epidemiological study has found that elevated liver ... with higher future mortality. The findings are in ... by John Wiley & Sons on behalf of ... Diseases (AASLD). The article is also available online ...
Cached Medicine News:Health News:Natural Nutrition Ships First InterACTIVE Nutrition Brand Products to Iraq 2Health News:Putting an End to Medical Cruelty: A Horrifying Article in Yahoo this Week by T. L. Kittle 2Health News:Putting an End to Medical Cruelty: A Horrifying Article in Yahoo this Week by T. L. Kittle 3Health News:Shared Health Partners With State of Tennessee to Provide Electronic Health Information for Statewide Health Information Network 2Health News:Live Healthier ... ZAP Those Germs! 2Health News:Johnson & Johnson and NBC Olympics Partner to Share the Stories of U.S. Olympic Hopefuls and Their Journeys to Beijing With The Family Room 2Health News:Johnson & Johnson and NBC Olympics Partner to Share the Stories of U.S. Olympic Hopefuls and Their Journeys to Beijing With The Family Room 3Health News:Johnson & Johnson and NBC Olympics Partner to Share the Stories of U.S. Olympic Hopefuls and Their Journeys to Beijing With The Family Room 4Health News:Johnson & Johnson and NBC Olympics Partner to Share the Stories of U.S. Olympic Hopefuls and Their Journeys to Beijing With The Family Room 5Health News:Johnson & Johnson and NBC Olympics Partner to Share the Stories of U.S. Olympic Hopefuls and Their Journeys to Beijing With The Family Room 6Health News:Elevated liver enzymes associated with higher future mortality 2
(Date:1/23/2015)... Biotherapeutics, Inc. (NASDAQ: NWBO )("NW Bio"), a U.S. ... inoperable solid tumor cancers, announced today that CEO Linda ... Phacilitate Immunotherapy Forum in Washington D.C. ... on January 26 at 10:30 a.m. EST at the Grand ...
(Date:1/23/2015)...  Pete Rose, baseball,s all-time hits leader, is the new spokesperson ... Ducere Pharma has announced. "Pete,s a Hall of ... him on board with Myoflex," said Ducere Pharma Chief Executive ... who is known across all generations. The passion and intensity ...
(Date:1/23/2015)... 23, 2015 Cord Blood America, Inc. ( www.cordblood-america.com ) ... "Company")  filed a Preliminary Proxy Statement, Schedule 14A, with the ... provides an update for shareholders detailing why a "YES" vote ... Dear Shareholders, As we reflect upon the ...
Breaking Medicine Technology:NW Bio To Present At The 7th Annual Phacilitate Immunotherapy Forum 2NW Bio To Present At The 7th Annual Phacilitate Immunotherapy Forum 3Pete Rose bets on Myoflex to relieve aches and pains 2Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 2Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 3Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 4
... - Roche today announced,results of a small study ... (peginterferon alfa-2b),and ribavirin due to adverse events within ... weeks of treatment with PEGASYS(R),(peginterferon alfa-2a) and ribavirin. ... go on and complete a full course of,treatment ...
... ACCEPTED FOR REVIEW BY,FDA- , BASEL, Switzerland and ... SPPN) today welcomed the significant new results from,clinical ... the 22nd Annual Scientific Meeting,and Exposition of the ... These results confirm the favourable safety and,efficacy profile, ...
Cached Medicine Technology:Data Suggest that Pegasys May be an Option in Hepatitis C Patients,Unable to Tolerate Peg-Intron 2Data Suggest that Pegasys May be an Option in Hepatitis C Patients,Unable to Tolerate Peg-Intron 3Data Suggest that Pegasys May be an Option in Hepatitis C Patients,Unable to Tolerate Peg-Intron 4Data Suggest that Pegasys May be an Option in Hepatitis C Patients,Unable to Tolerate Peg-Intron 5Data Suggest that Pegasys May be an Option in Hepatitis C Patients,Unable to Tolerate Peg-Intron 6New Data Highlights Potential of SPP100 (Tekturna) as Gold Standard,Therapy in Treatment of Hypertension 2New Data Highlights Potential of SPP100 (Tekturna) as Gold Standard,Therapy in Treatment of Hypertension 3New Data Highlights Potential of SPP100 (Tekturna) as Gold Standard,Therapy in Treatment of Hypertension 4New Data Highlights Potential of SPP100 (Tekturna) as Gold Standard,Therapy in Treatment of Hypertension 5New Data Highlights Potential of SPP100 (Tekturna) as Gold Standard,Therapy in Treatment of Hypertension 6New Data Highlights Potential of SPP100 (Tekturna) as Gold Standard,Therapy in Treatment of Hypertension 7New Data Highlights Potential of SPP100 (Tekturna) as Gold Standard,Therapy in Treatment of Hypertension 8New Data Highlights Potential of SPP100 (Tekturna) as Gold Standard,Therapy in Treatment of Hypertension 9New Data Highlights Potential of SPP100 (Tekturna) as Gold Standard,Therapy in Treatment of Hypertension 10New Data Highlights Potential of SPP100 (Tekturna) as Gold Standard,Therapy in Treatment of Hypertension 11
... used screening test for determining the presence ... branded system is considered the manual standard, ... other system meets defined NCCLS/ICSH guidelines designed ... systems are also available for pediatric applications, ...
The HEMOCHRON Signature Elite offers state-of-the-art features like barcode scanning, internal Electronic Quality Control (EQC), QC Lockout and alphanumeric data entry for Patient Identification (PID...
Inquire...
The Minilyser offers a combination of three well proven instruments for fully automated processing of microplates. The Minilyser is the optimal fully automated ELISA and EIA equipment for laboratorie...
Medicine Products: