Navigation Links
JCI table of contents: Nov. 21, 2007
Date:11/21/2007

EDITOR'S PICK: Pregnant women pass on the effects of smoking

Smoking during pregnancy has many adverse effects on fetal development. A new study in mice by Andrea Jurisicova and colleagues at the University of Toronto, Canada, now adds the possibility that smoking before pregnancy or while breast-feeding might substantially decrease the fertility of female offspring to the long list of possible negative outcomes.

The authors found that female mice injected under the skin with polycyclic aromatic hydrocarbons (PAHs) environmental toxins found in cigarette smoke pre-pregancy or while lactating were found to have normal sized litters. However, their female offspring had markedly reduced numbers of resting and early growing follicles cell clusters that each contain a single egg. Further analysis indicated that the effects of PAHs on the number of follicles in female offspring were mediated through the aryl hydrocarbon receptor (Ahr), which upregulated expression of the gene Harakiri that makes a protein that causes cells to die by a process known as apoptosis. The potential importance of these findings for women of child-bearing age was demonstrated by the observation that PAHs triggered similar molecular pathways in human ovarian tissue transplanted into immunocompromised mice.

TITLE: Maternal exposure to polycyclic aromatic hydrocarbons diminishes murine ovarian reserve via induction of Harakiri

AUTHOR CONTACT:

Andrea Jurisicova
University of Toronto, Mount Sinai Hospital, Toronto, Ontario, Canada.
Phone: (416) 586-4800, ext. 2052; Fax: (416) 586-8588; E-mail: jurisicova@mshri.on.ca.

MEDIA CONTACT:

Jodi Salem
Media and Communications Specialist
Mount Sinai Hospital, Toronto, Ontario, Canada.
Phone: (416) 586-4800, ext. 8306; Fax: (416) 586-8544; E-mail: jsalem@mtsinai.on.ca<
'/>"/>

Contact: Karen Honey
press_releases@the-jci.org
215-573-1850
Journal of Clinical Investigation
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8 9 10

Related medicine news :

1. Ranbaxy Receives Tentative Approval to Manufacture and Market Galantamine Tablets on an Exclusive Basis
2. Schering-Plough/Merck Pharmaceuticals Announce FDA Filing Acceptance of New Drug Application for Loratadine/Montelukast Tablet
3. JCI table of contents: Sept. 4, 2007
4. FDA Seeks to Regulate Complementary and Alternative Medicine; Products Such as Vegetable Juice Could Be Restricted for Medical Use
5. Actavis Launches Carvedilol Tablets in the U.S.
6. Mylan Announces Final FDA Approval for Carvedilol Tablets
7. Ranbaxy Gains Approval to Manufacture and Market Carvedilol Tablets in the U.S. Market
8. Actavis Launches Amlodipine Tablets in the U.S.
9. Implantable device designed to detect, stop seizures under study at MCG
10. Stevens Health, Technology and Society roundtable: Sept. 19
11. Fruity vegetables and fish reduce asthma and allergies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/25/2015)... Sports controversies continue to revolve around issues of abuse ... case with the Miami Dolphins and Richie Incognito, or off the ... Rice domestic abuse case. In a recent episode of SCI ... implications of locker room culture on teams. He examines what worked ... do to improve the locker room as a work place. ...
(Date:4/24/2015)... Will County, Illinois (PRWEB) April 24, 2015 ... 2015 event includes septic tank pumping ( http://www.zeitersseptics.com/multi-customer-discount.html ) ... of 3-customers to start the program. This does not ... may be applicable. Save $25-$65 per person. If someone ... Aerobic/Mechanical unit, or two tanks totaling approximately 2500 gallons ...
(Date:4/24/2015)... York (PRWEB) April 24, 2015 ... move forward in the federal multidistrict litigation underway ... According to court documents, the parties involved in ... April 16th detailing, among other things, preparation for ... that counsel for both plaintiffs and defendants have ...
(Date:4/24/2015)... Carinsurancequotesinfo.com has released a new blog post has ... qualify for auto insurance as a single parent. ... online, without having to follow a special process. The ... reduce their auto insurance expenses. The tips are presented ... , Clients can now visit an insurance brokerage website ...
(Date:4/24/2015)... St. Joseph, Missouri (PRWEB) April 24, 2015 ... solutions for veterinarians , UGA is now proud to ... oversee the care of 16,000 animals a year. This ... afford care for their animals. , After providing ... of Missouri Veterinary Medical Teaching Hospital (VMTH) wanted to ...
Breaking Medicine News(10 mins):Health News:David Steele Discusses Locker Room Culture on SCI TV 2Health News:David Steele Discusses Locker Room Culture on SCI TV 3Health News:Zeiter's Septics Inc. Offers Multi Customer Septic Tank Cleaning Program in Cook, Putnam & Will Counties in May 2015 2Health News:Zeiter's Septics Inc. Offers Multi Customer Septic Tank Cleaning Program in Cook, Putnam & Will Counties in May 2015 3Health News:Federal Lipitor Lawsuits Progress, as New Status Report Details Preparation for Upcoming Bellwether Trials 2Health News:Federal Lipitor Lawsuits Progress, as New Status Report Details Preparation for Upcoming Bellwether Trials 3Health News:Auto Insurance Discounts for Single Parents - How to Qualify for Low Rates 2Health News:University of Missouri Veterinary Medical Teaching Hospital Teams with UGA 2
... The National,Osteoporosis Foundation (NOF) has teamed up ... tour starting September 8th and culminating on,October 20th, ... to Start Right, Stay Strong for bone health. ... that offers individuals information on bone,health, exercise, and ...
... Health Accountability Foundation,s Report Card Provides Information on ... Quality, Mortality, Cost, LAKE SUCCESS, N.Y., Sept. 6 ... New Jersey have a unique new tool for evaluating,the ... State Health,Accountability Foundation,s first New York Regional Health Care ...
... Stryker Corporation,(NYSE: SYK ) announced that it ... at 4:30 p.m., Eastern Time, to discuss the Company,s,operating ... provide an,operational update. Operating results for the quarter ended ... day. Stephen P. MacMillan, President and Chief Executive ...
... in the stomach, this combo encourages carcinogens, study suggests ... is present in the stomach, vitamin C transforms from ... research suggests. , Researchers at Western Infirmary in Glasgow, ... (fat) in the upper stomach, which is particularly vulnerable ...
... Hospital have diagnosed two patients affected with vocal cord ... to irritating agents that are breathed in at the ... cases of patients with occupational vocal dysfunction. , Vocal ... in the vocal cords when inhaling. Under normal conditions, ...
... Two new issue briefs from,HealthFitness (OTC Bulletin Board: ... employer partners to create a culture of health. ... America Embraces New Culture of Health" features,HealthFitness CEO ... proactive vision for corporations to address the high ...
Cached Medicine News:Health News:National Osteoporosis Foundation Teams Up With Ladies Home Journal Magazine to Launch a 10-city Mall Walk Tour 2Health News:First New York/New Jersey Health Care Report Card Released 2Health News:First New York/New Jersey Health Care Report Card Released 3Health News:First New York/New Jersey Health Care Report Card Released 4Health News:First New York/New Jersey Health Care Report Card Released 5Health News:Stryker To Host Conference Call on October 17, 2007 2Health News:Vitamin C Plus Fat Might Spur Cancer 2Health News:Vocal cord dysfunction may be caused by work 2Health News:HealthFitness CEO Supports Move Toward Cultural Shift, and Science-Based Health Management Programming 2Health News:HealthFitness CEO Supports Move Toward Cultural Shift, and Science-Based Health Management Programming 3
(Date:4/24/2015)... 2015 In today,s ever-changing and increasingly ... the world to access diverse skill sets, set ... are many areas to misstep in the process ... practices are necessary and beneficial in order to ... to research by benchmarking firm, Best Practices, LLC, ...
(Date:4/24/2015)... April 24, 2015  Span-America Medical Systems, Inc. ... its fiscal 2015 second quarter results on Thursday, April ... The company will conduct a conference call ... to review the company,s financial and operating results for ... broadcast of the conference call will be available ...
(Date:4/24/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/pmbmv2/global_biobanking ... Biobanking Market 2015-2019" report to their offering. ... grow at a CAGR of 7.07% over the period ... divided into two segments: Equipment and Consumables. This report ... the Global Biobanking market for the period 2015-2019. ...
Breaking Medicine Technology:Work Around the Clock: Building Effective Global Capabilities 2Global Biobanking Market Report 2015-2019 - Increase in Strategic Collaborations with Beckman Coulter, Tecan & Thermo Fischer Scientific Dominating 2
... 2011 Cumberland Pharmaceuticals Inc. (Nasdaq: ... care and gastroenterology markets, today announced fourth quarter and full ... For the three months ended December 31, 2010, net revenue ... corresponding period in 2009. This quarterly revenue growth was largely ...
... Hill-Rom Holdings, Inc. (NYSE: HRC ) today ... immediately. "I am pleased to have someone of ... Mark Guinan, Senior Vice President and Chief Financial Officer of ... will contribute to the solid financial leadership of our company ...
Cached Medicine Technology:Cumberland Pharmaceuticals Reports Fourth Quarter and Full Year 2010 Financial Results 2Cumberland Pharmaceuticals Reports Fourth Quarter and Full Year 2010 Financial Results 3Cumberland Pharmaceuticals Reports Fourth Quarter and Full Year 2010 Financial Results 4Cumberland Pharmaceuticals Reports Fourth Quarter and Full Year 2010 Financial Results 5Cumberland Pharmaceuticals Reports Fourth Quarter and Full Year 2010 Financial Results 6Cumberland Pharmaceuticals Reports Fourth Quarter and Full Year 2010 Financial Results 7Cumberland Pharmaceuticals Reports Fourth Quarter and Full Year 2010 Financial Results 8Cumberland Pharmaceuticals Reports Fourth Quarter and Full Year 2010 Financial Results 9Cumberland Pharmaceuticals Reports Fourth Quarter and Full Year 2010 Financial Results 10Cumberland Pharmaceuticals Reports Fourth Quarter and Full Year 2010 Financial Results 11Cumberland Pharmaceuticals Reports Fourth Quarter and Full Year 2010 Financial Results 12Cumberland Pharmaceuticals Reports Fourth Quarter and Full Year 2010 Financial Results 13
... Varicella-Zoster Virus (VZV) IgG Enzyme-Linked Immunosorbent ... and quantitative determination of IgG antibody to ... specimens may be used for the determination ... convalescent, may be used to demonstrate seroconversion ...
... Inc. Mumps IgG ELISA test system is ... IgG antibody in human serum. When performed ... this test, together with other clinical information, ... status, and/or aid in the diagnosis of ...
... Mumps IgM Enzyme-Linked Immunosorbent Assay ... qualitative detection of IgM antibody ... for the determination of immunological ... this kit have not been ...
The CALBIOTECH, INC. (CBI), Mumps IgM ELISA tests system is an enzyme linked immunosorbent assay (ELISA) for the detection of IgM class antibodies to Mumps in human serum or plasma....
Medicine Products: