Navigation Links
JCI table of contents: Nov. 21, 2007
Date:11/21/2007

EDITOR'S PICK: Pregnant women pass on the effects of smoking

Smoking during pregnancy has many adverse effects on fetal development. A new study in mice by Andrea Jurisicova and colleagues at the University of Toronto, Canada, now adds the possibility that smoking before pregnancy or while breast-feeding might substantially decrease the fertility of female offspring to the long list of possible negative outcomes.

The authors found that female mice injected under the skin with polycyclic aromatic hydrocarbons (PAHs) environmental toxins found in cigarette smoke pre-pregancy or while lactating were found to have normal sized litters. However, their female offspring had markedly reduced numbers of resting and early growing follicles cell clusters that each contain a single egg. Further analysis indicated that the effects of PAHs on the number of follicles in female offspring were mediated through the aryl hydrocarbon receptor (Ahr), which upregulated expression of the gene Harakiri that makes a protein that causes cells to die by a process known as apoptosis. The potential importance of these findings for women of child-bearing age was demonstrated by the observation that PAHs triggered similar molecular pathways in human ovarian tissue transplanted into immunocompromised mice.

TITLE: Maternal exposure to polycyclic aromatic hydrocarbons diminishes murine ovarian reserve via induction of Harakiri

AUTHOR CONTACT:

Andrea Jurisicova
University of Toronto, Mount Sinai Hospital, Toronto, Ontario, Canada.
Phone: (416) 586-4800, ext. 2052; Fax: (416) 586-8588; E-mail: jurisicova@mshri.on.ca.

MEDIA CONTACT:

Jodi Salem
Media and Communications Specialist
Mount Sinai Hospital, Toronto, Ontario, Canada.
Phone: (416) 586-4800, ext. 8306; Fax: (416) 586-8544; E-mail: jsalem@mtsinai.on.ca<
'/>"/>

Contact: Karen Honey
press_releases@the-jci.org
215-573-1850
Journal of Clinical Investigation
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8 9 10

Related medicine news :

1. Ranbaxy Receives Tentative Approval to Manufacture and Market Galantamine Tablets on an Exclusive Basis
2. Schering-Plough/Merck Pharmaceuticals Announce FDA Filing Acceptance of New Drug Application for Loratadine/Montelukast Tablet
3. JCI table of contents: Sept. 4, 2007
4. FDA Seeks to Regulate Complementary and Alternative Medicine; Products Such as Vegetable Juice Could Be Restricted for Medical Use
5. Actavis Launches Carvedilol Tablets in the U.S.
6. Mylan Announces Final FDA Approval for Carvedilol Tablets
7. Ranbaxy Gains Approval to Manufacture and Market Carvedilol Tablets in the U.S. Market
8. Actavis Launches Amlodipine Tablets in the U.S.
9. Implantable device designed to detect, stop seizures under study at MCG
10. Stevens Health, Technology and Society roundtable: Sept. 19
11. Fruity vegetables and fish reduce asthma and allergies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... (PRWEB) September 18, 2014 Specialty ... in Westlake, OH, announces that they have achieved ... PowerServer, a Complete Certified Ambulatory EHR-certified system developed ... Specialty Teleradiology had a non MU compliant PACS ... their business grew from a niche in oncology ...
(Date:9/18/2014)... Doylestown, PA (PRWEB) September 18, 2014 ... month by successfully launching its first product a mere ... F PRIME™ is a high performance glycan release enzyme ... assurance, glycobiology research, and the basis for tissue pathology ... Bulldog Bio (Portsmouth, NH) for the North American market ...
(Date:9/18/2014)... 9Lover.com, an internationally well-known designer and leader in ... promotion for its maternity wedding outfits. Now, all the ... maternity wedding dresses on its website. , ... consumers. The company’s development manager believes the cheap maternity ... The current special offer will last until September 29, ...
(Date:9/17/2014)... 2014 Today, Fecbek, a leading dress manufacturer ... special occasion gowns. These are a lot of beautiful A-line ... new range. , A skirt is a tube- or ... or part of the legs. In the western world, skirts ... be a draped garment which is made out of a ...
(Date:9/17/2014)... Recently, UWDress.com, an innovative company that ... occasion outfits, has released its 2014 empire waist ... has launched a big sale for these new and ... deeply discounted rates, from 15 to 65 percent off. ... on using comfortable to wear materials. Its elegant items ...
Breaking Medicine News(10 mins):Health News:Specialty Teleradiology Attains Meaningful Use with PowerServer MU 2Health News:Specialty Teleradiology Attains Meaningful Use with PowerServer MU 3Health News:N-Zyme Scientifics Announces Successful Product Launch 2Health News:Discounted Maternity Wedding Dresses For 2014 Introduced By 9Lover.com 2Health News:Fecbek.com Has Recently Announced Its New Series of Delicate Special Occasion Gowns Online 2Health News:2014 Empire Waist Evening Dress Collection Now Unveiled At UWDress.com 2
... Sweden: Two trials presented at the Heart Failure Congress 2011, ... European Society of Cardiology (HFA of the ESC), will help ... heart failure (CHF) in whom telemedical management delivers benefits. ... Late Breaking Session 1 - revealed that telemonitoring showed significant ...
... By Steven Reinberg HealthDay Reporter , FRIDAY, ... benefits of robotic surgery on their websites without solid ... researchers report. In fact, four out of 10 ... robotic surgery is better than conventional surgery, an assertion ...
... May 21 (HealthDay News) -- As summer approaches and ... experts say. "We are not invincible when it ... an athletic trainer with the University of Tennessee at ... Medical and Science Advisory Board, in a news release ...
... chemotherapy is used to kill cancer cells, it can also ... bone marrow and blood cells, often limiting the ability to ... Cancer Research Center reported at today,s annual meeting of the ... one possible approach to reduce this toxic effect on bone ...
... York, NY (May 20, 2011)The American Federation for Aging Research ... 83 advanced fellows and junior faculty at 27 Centers of ... This effort, funded with support from the John A. Hartford ... create the cadre of academic leaders in geriatrics. As our ...
... , FRIDAY, May 20 (HealthDay News) -- Treating chronic ... and function, according to a new study. Prior research ... problems and reduced gray matter in brain areas that play ... pain, such as anxiety and depression. But it wasn,t clear ...
Cached Medicine News:Health News:Telemonitoring can improve overall survival of HF patients 2Health News:Telemonitoring can improve overall survival of HF patients 3Health News:Telemonitoring can improve overall survival of HF patients 4Health News:Telemonitoring can improve overall survival of HF patients 5Health News:Robotic Surgery Oversold on Hospital Websites, Study Contends 2Health News:Robotic Surgery Oversold on Hospital Websites, Study Contends 3Health News:Robotic Surgery Oversold on Hospital Websites, Study Contends 4Health News:Keeping Cool in the Heat 2Health News:Gene-modified stem cells help protect bone marrow from toxic side effects of chemotherapy 2Health News:AFAR announces the 2011 Hartford Scholars in Geriatric Medicine 2
(Date:9/17/2014)... -- According to a new market research ... Device, Display, & Microprocessor/MCU), by Application (Imaging, Medical Therapeutics, ... - Global Forecast to 2020", published by MarketsandMarkets, the ... reach $56.50 Billion by 2020, growing at a CAGR ... 235 market data Tables and 71 Figures spread through ...
(Date:9/17/2014)... , Sept. 17, 2014  NuView Life ... global licensing and collaboration agreement with Otsuka Pharmaceutical ... NuView,s investigative genomic-based diagnostic biomarker to detect cancers ... includes all other future diagnostic-imaging applications. NuView retains ... therapeutic delivery and in-vitro urine screen applications. ...
(Date:9/17/2014)... , Sept. 17, 2014 Isis ... that it has earned a $4 million milestone ... ) associated with the initiation of a Phase ... multi-drug resistant (MDR), gram-negative bacterial infections.  The Phase ... to evaluate the efficacy and safety of plazomicin ...
Breaking Medicine Technology:Medical Electronics Market Worth $56.50 Billion by 2020 2Medical Electronics Market Worth $56.50 Billion by 2020 3Medical Electronics Market Worth $56.50 Billion by 2020 4NuView Life Sciences Enters Global Licensing Agreement With Otsuka Pharmaceutical 2NuView Life Sciences Enters Global Licensing Agreement With Otsuka Pharmaceutical 3NuView Life Sciences Enters Global Licensing Agreement With Otsuka Pharmaceutical 4NuView Life Sciences Enters Global Licensing Agreement With Otsuka Pharmaceutical 5Isis Pharmaceuticals Earns $4 Million from Achaogen for the Initiation of a Phase 3 Study of Plazomicin 2Isis Pharmaceuticals Earns $4 Million from Achaogen for the Initiation of a Phase 3 Study of Plazomicin 3
100cc silicone evacuator with hubless flat drain and trocar...
Used following open gallbladder procedure to drain bile. Often attached to Bard bile bag....
Silicone Flat Hubless Drains...
Hubbed drains are made of translucent silicone and include a full-length X-ray opaque stripe....
Medicine Products: