Navigation Links
JCI table of contents: May 22, 2008
Date:5/22/2008

e: 81-3-3357-6156; Fax: 81-3-3357-6156; E-mail: thibi@sc.itc.keio.ac.jp.

View the PDF of this article at: https://www.the-jci.org/article.php?id=34610


VIROLOGY: CD4+ T cells really are home sweet home for the monkey relative of HIV

Many strains of monkey become naturally infected with viruses that are related to HIV. These viruses are known collectively as SIV and naturally infected monkeys do not develop AIDS. It is hoped that understanding why monkeys naturally infected with SIV do not develop AIDS might teach researchers important lessons about the mechanisms underlying the development of AIDS in humans infected with HIV and identify ways to prevent this happening. New insight into the mechanisms that control the number of virus particles in the blood of sooty mangabeys naturally infected with SIVsmm, the strain of SIV that naturally infects sooty mangabeys, has now been provided by a team of researchers from the University of Pennsylvania, Philadelphia, and Emory University, Atlanta.

HIV and SIV infect immune cells known as CD4+ T cells. So, the authors set out to determine how CD4+ T cells affected the number of virus particles in the blood of sooty mangabeys naturally infected with SIVsmm did they provide immune control of the number of virus particles or did they simply provide a place to live a replicate. The number of SIVsmm particles in the blood of naturally infected sooty mangabeys decreased when the monkeys were depleted of CD4+ T cells and then increased again as the number of proliferating CD4+ T cells rebounded. So, it was concluded that availability of proliferating CD4+ T cells is a key determinant of how many SIVsmm particles can be detected in the blood of naturally infected sooty mangabeys, rather than CD4+ T cells providing immune control of the virus.

TITLE: Availability of a
'/>"/>

Contact: Karen Honey
press_releases@thje-jci.org
215-573-1850
Journal of Clinical Investigation
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8 9 10 11

Related medicine news :

1. New Survey Suggests That Consumers Are Naive to the Risk of Botox Parties and the Importance of FDA Approval for Cosmetic Injectables
2. Eat Your Vegetables - That Means You, Parents!
3. Biotel Announces Profitable Third Quarter Ended March 31, 2008
4. Mylan Launches Paroxetine Hydrochloride Extended-Release Tablets
5. FDA Approves NOVO NORDISKs NovoSeven(R) RT (Coagulation Factor VIIa [Recombinant] Room Temperature Stable) for Hemophilia Patients With Inhibitors
6. Dawning Technologies, Inc. Releases JavaLin/PDI Portable Device Interface
7. SEIU Members to Politicians: Live Up to Your Promises or We Will Hold You Accountable
8. Dr. Arnold Klein Warns of Dangers With Permanent and Longer Lasting Injectable Fillers
9. Roxane Laboratories, Inc. Announces the Launch of Acarbose Tablets
10. After divorce, stable families help minimize long-term harm to children
11. Pilot study reinforces use of portable anteroom HEPA filtration
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/25/2015)... May 25, 2015 According to a ... market growth in hip external fixation market is driven ... U.S. population and advancements in infection prevention technologies. As ... fractures are currently accounting for the largest total number ... with falls and accidents. As a result, the average ...
(Date:5/25/2015)... May 25, 2015 Join Fiona's Soccer Camp ... two-hour instructional clinic. Irish National Player, Fiona O'Sullivan will ... them a taste of her coaching style. Fiona has three ... Camps in Novato are at Lynwood Elmentary School (June 15-19) ... High School - June 6th, 2015 - 1:00-3:00pm. Bring a ...
(Date:5/24/2015)... Pacific Prime has announced that they have launched the ... cost of individual international health insurance. Titled: The Cost of Health ... of health insurance in six top expat destinations, which are also ... Hong Kong , Singapore , China , ... the UK , Article 2 presents an in-depth look ...
(Date:5/24/2015)... May 24, 2015 Scientists with Cardno ... on air quality compliance issues that may have raised ... Surviving Mesothelioma has just posted an article on the ... , The group found airborne asbestos levels well above ... between 1984 and 2011. , “Asbestos compliance sampling data ...
(Date:5/24/2015)... 2015 Medicx Media Solutions ... executive Jay Krihak as its head of programmatic ... up its expertise and leadership position in the ... Health sectors. , Krihak is an experienced, award-winning ... Krihak led sales planning teams for mobile platform ...
Breaking Medicine News(10 mins):Health News:DePuy Synthes and Stryker Lead Orthopedic External Fixation Trauma Device Market Due to Increased Hip Fractures in the U.S. 2Health News:DePuy Synthes and Stryker Lead Orthopedic External Fixation Trauma Device Market Due to Increased Hip Fractures in the U.S. 3Health News:US Sports Camps and Nike Soccer Camps Offer Complimentary Instructional Clinic with Fiona's Soccer Camp 2Health News:Pacific Prime Releases 2nd Article of Cost of Health Insurance Report 2Health News:New Analysis Finds Too Many Employers Ignored OSHA Asbestos Guidelines, According to Surviving Mesothelioma 2Health News:Medicx Media Solutions Expands Executive Team 2
... News) -- Intensive control of blood sugar levels reduces ... diabetics, new research indicates. However, the evidence did ... actually developing severe kidney disease. The two signs ... conditions known as microalbuminuria and macroalbuminuria. These are characterized ...
... (May 29, 2012) Researchers from South Korea, Sweden, ... to restore neuron function to parts of the brain ... pluripotent stem cells into animal models. Induced ... human somatic cells such as skin, and can be ...
... May 29, 2012 Older adults who don,t get ... exposure may be at increased risk of developing mobility ... Baptist Medical Center. , "This is one of the first ... the onset of new mobility limitations or disability in older ...
... genetic disorders have uncovered insights into those diseases ... divide. Focusing on the cohesin complex, a group ... pairs, scientists have discovered mutations that disrupt cohesin, ... cohesinopathies. "We are learning more about how ...
... May 29, 2012 -- The discovery of a mummified ... scientific team to conduct a genetic analysis on a liver ... C2 sequence common in Southeast Asia. Additional analysis ... model to study the evolution of chronic hepatitis B and ...
... Texas For 50 years scientists have been unsure how the ... basic innate immune responses. That mystery has now been solved, thanks ... The answers may help clear the way for a ... such as V. cholerae , but instead disable their defenses ...
Cached Medicine News:Health News:Tight Blood-Sugar Control Shows Mixed Results for Health of Kidneys: Study 2Health News:Researchers restore neuron function to brains damaged by Huntington's disease 2Health News:Older adults may need more vitamin D to prevent mobility difficulties 2Health News:Mutations impair childhood growth and development by disrupting organization of chromosome pairs 2Health News:16th-century Korean mummy provides clue to hepatitis B virus genetic code 2Health News:50-year cholera mystery solved 2
(Date:5/21/2015)... , May 21, 2015 ... has announced the addition of the ... their offering. ,     (Logo: http://photos.prnewswire.com/prnh/20130307/600769) , ,The ... and size the world market for Arthroscopy ... identifies trends impacting the market for these ...
(Date:5/21/2015)... 21, 2015  (MUSE Booth # 1510)What:Automating continuous ... (EHR) is invaluable in any hospital setting, but ... a requirement and mainstream in healthcare, the integration ... EHR is gaining traction in MEDITECH facilities.During MUSE ... Site Project Manager & Clinical Analyst at McLaren ...
(Date:5/21/2015)... England , May 21, 2015 ... Bekämpfung von Arzneimittelfälschungen - Zwecks Leistungsvergleich ... Arzneimittelprüfdienstes wird auf EG-Mitgliedstaaten verwiesen, in ... betrieben werden.  Wählen Sie ein Aegate-Land: ... der Richtlinie zur Bekämpfung von Arzneimittelfälschungen ...
Breaking Medicine Technology:Analysing Arthroscopy Devices Markets Worldwide 2014-2020 2Analysing Arthroscopy Devices Markets Worldwide 2014-2020 3Hospital Streamlines ICU Efficiency with Timely Data Integration 2Hospital Streamlines ICU Efficiency with Timely Data Integration 3EU-Arzneimittel-Richtlinie für gefälschte Medikamente; Aegate-Zusammenfassung als reale Bewertung aus Belgien 2EU-Arzneimittel-Richtlinie für gefälschte Medikamente; Aegate-Zusammenfassung als reale Bewertung aus Belgien 3
... , April 29, 2010 Albireo today,announced ... recent study,assessing the safety, tolerability and efficacy of A3309 ... compound for,the treatment of irritable bowel syndrome with constipation ... during the 2010,Digestive Disease Week (DDW) annual meeting being ...
... SALT LAKE CITY , April 28 Sonic Innovations, ... Administration (VA), is conducting ongoing training events for government clinicians.  The company ... in San Diego, California and April 25 through ... for May 3 through 5 in Salt Lake City, ...
Cached Medicine Technology:Albireo Announces Positive Results From a Study With A3309 in Patients With Chronic Constipation 2Albireo Announces Positive Results From a Study With A3309 in Patients With Chronic Constipation 3Albireo Announces Positive Results From a Study With A3309 in Patients With Chronic Constipation 4Albireo Announces Positive Results From a Study With A3309 in Patients With Chronic Constipation 5Sonic Innovations Conducts National Training Events for Government Clinicians 2Sonic Innovations Conducts National Training Events for Government Clinicians 3
BD Vacutainer® Heparin Tubes are spray-coated with either lithium heparin or sodium heparin and are used for plasma determinations in chemistry....
VACUETTE paediatric tubes have decreased sample volumes and are ideal for small childrens' veins and geriatric patients....
VACUETTE paediatric tubes have decreased sample volumes and are ideal for small childrens' veins and geriatric patients....
Inquire...
Medicine Products: