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JCI table of contents: March 23, 2009
Date:3/23/2009

odyinduced nephritis in mice and humans

AUTHOR CONTACT:
Chandra Mohan
University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Phone: (214) 648-9675; Fax: (214) 648-7995; E-mail: chandra.mohan@utsouthwestern.edu.

Edward Wakeland
University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Phone: (214) 648-7332; Fax: (214) 648-7995; E-mail: ward.wakeland@utsouthwestern.edu.

Marta Alarcn-Riquelme
Uppsala University, Uppsala, Sweden.
Phone: 46-18-4714805; Fax: 46-18-4714808; E-mail: marta.alarcon@genpat.uu.se.

View the PDF of this article at: https://www.the-jci.org/article.php?id=36728

ACCOMPANYING COMMENTARY
TITLE: Kallikreins and lupus nephritis

AUTHOR CONTACT:
Claudio Ponticelli
IRCCS Istituto Clinico Humanitas, Milano, Italy.
Phone: 39-0226112952; Fax: 39-0226112951; E-mail: claudio.ponticelli@fastwebnet.it.

View the PDF of this article at: https://www.the-jci.org/article.php?id=38786


DERMATOLOGY: The protein SRF keeps the skin healthy

Sabine Werner and colleagues, at the Institute of Cell Biology, ETH Zrich, Switzerland, have determined a role for the protein SRF in the skin and found that its expression is markedly decreased in the diseased areas of skin of individuals with psoriasis.

In the study, human skin cells known as keratinocytes were found to express high levels of SRF when healthy but only low levels when psoriatic and when wounded. Mice lacking SRF in keratinocytes during embryonic development died in utero, whereas mice in which SRF was absent in
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Contact: Karen Honey
press_releases@the-jci.org
215-573-1850
Journal of Clinical Investigation
Source:Eurekalert

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