Navigation Links
JCI table of contents: June 23, 2011
Date:6/23/2011

h Institute, Portland, has now identified in mice the molecular mechanism responsible for the antiepileptic effects of the ketogenic diet.

The team found that a ketogenic diet reduces seizures in mice by decreasing expression of the protein Adk, which is responsible for clearing the natural antiepileptic agent adenosine from the brain. The clinical relevance of these data are highlighted by the team's finding that brain tissue from patients with epilepsy that fails to respond to treatment with conventional drugs shows increased levels of Adk. The team suggests that their data could lead to the development of less-restrictive antiepileptic diets and alternate pharmaceutical approaches to treatment, notions with which Robert Greene, at The University of Texas Southwestern Medical Center, Dallas, concurs in an accompanying commentary.

TITLE: A ketogenic diet suppresses seizures in mice through adenosine A1 receptors

AUTHOR CONTACT:
Detlev Boison
Legacy Research Institute, Portland, Oregon, USA.
Phone: 503.232.0589; Fax: 503.232.5465; E-mail: dboison@downeurobiology.org.

View this article at: http://www.jci.org/articles/view/57813?key=b823f84a9a31512e6849

ACCOMPANYING COMMENTARY
TITLE: Adenosine: front and center in linking nutrition and metabolism to neuronal activity

AUTHOR CONTACT:
Robert W. Greene
The University of Texas Southwestern Medical Center and Dallas VA Medical Center, Dallas, Texas, USA.
Phone: 214.648.5108; Fax: 214.648.7037; E-mail: robertw.greene@utsouthwestern.edu.

View this article at: http://www.jci.org/articles/view/58391?key=dc1ba8608a2fa737a42f


EDITOR'S PICK: "Good" cho
'/>"/>

Contact: Karen Honey
press_releases@the-jci.org
734-546-5242
Journal of Clinical Investigation
Source:Eurekalert

Page: 1 2 3 4 5 6 7

Related medicine news :

1. Implantable Device May Help Ease Tough Migraines
2. Portable Pools Pose Drowning Risk for Young Kids
3. New study uncovers the dangers of portable pools
4. JCI online early table of contents: June 13, 2011
5. Study confirms safety, cancer-targeting ability of nutrient in broccoli, other vegetables
6. JCI online early table of contents: June 1, 2011
7. Gestational Diabetes Predictable Before Pregnancy, Experts Say
8. Shave biopsy is a safe and acceptable method for initial evaluation of melanoma
9. Diet high in vegetables and fruit associated with less weight gain in African-American women
10. Most common form of inherited intellectual disability may be treatable
11. Women & Infants receives support from CVS Caremark Charitable Trust
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/4/2015)... ... August 04, 2015 , ... PerceptiMed, ... Richard Carmona, M.D., M.P.H., FACS, to its Board of Directors effective August 1, ... lives," Dr. Carmona said. "I strongly believe in the mission of the company ...
(Date:8/4/2015)... , ... August 04, 2015 , ... ... Local Food,” scheduled for Nov. 3 – 4, 2015, at UC San Diego, ... create new businesses, improve food access, and manage resources efficiently against the dueling ...
(Date:8/4/2015)... ... ... Many men are confused about the safety of testosterone replacement therapy. In ... voice of authority for men seeking accurate information about testosterone. , Renew Man™ ... in the safe and effective treatment of low testosterone. In recent years, the experts ...
(Date:8/4/2015)... ... August 04, 2015 , ... They say a picture is worth a thousand ... and medical art can be essential. StayWell, a health solutions company, announced today it ... solutions have been used by physicians and other health care providers for more than ...
(Date:8/4/2015)... ... August 04, 2015 , ... Discovia, a leading ... announced that John Munro, a 15-year veteran of the eDiscovery services industry, has ... , “I am thrilled to join Discovia at this important point in its ...
Breaking Medicine News(10 mins):Health News:Dr. Richard Carmona, 17th Surgeon General of the United States, Joins PerceptiMed, Inc.’s Board of Directors 2Health News:Dr. Richard Carmona, 17th Surgeon General of the United States, Joins PerceptiMed, Inc.’s Board of Directors 3Health News:Diversity of Urban and Hydroponic Farms of the Future to Highlight Seedstock Annual Conference Field Trip 2Health News:Diversity of Urban and Hydroponic Farms of the Future to Highlight Seedstock Annual Conference Field Trip 3Health News:New Video from Renew Man™ Raises Awareness of the Right Way to Correct Low Testosterone 2Health News:New Video from Renew Man™ Raises Awareness of the Right Way to Correct Low Testosterone 3Health News:StayWell Offers Instant Downloads, Licensing of Medical Art to Improve Patient Education 2Health News:StayWell Offers Instant Downloads, Licensing of Medical Art to Improve Patient Education 3Health News:John Munro Joins eDiscovery Leader Discovia as Vice President of Managed Services Operations 2Health News:John Munro Joins eDiscovery Leader Discovia as Vice President of Managed Services Operations 3
... the sentencing of actor Sylvester Stallone came as an anti-climax ... Sydney. ,He was fined $2,975 for bringing banned ... of $10,000. ,A Customs search of his luggage ... February last had revealed 48 vials of the banned human ...
... of those suffering from AIDS came forth as hundreds of ... there to support them, gathered at a candlelight memorial ... AIDS Candlelight Memorial Day late Sunday saw more than 500 ... wearing white T-shirts and holding a candles. The third Sunday ...
... American bio-pharmaceutical major Gilead, which has entered into generic ... its HIV drug Viread, is hoping to get a ... made considerable progress in implementing our access programme and ... a pricing of $1 a day for the pill," ...
... According to a new study, repeated exposure to one person's ... shared opinions from multiple people. , ,This ... recipients sense of familiarity and in some cases gives a ... then it actually is. , ,In a series ...
... is on in the US to rein in sexual offenders ... safer for everyone. ,Social networking sites allow users ... and let them send messages to one another and, in ... MySpace had initially balked when attorneys general from eight states ...
... in the Shangdong province of eastern China have been afflicted ... has since been contained, state news agency Xinhua has reported. ... and another 393 people mostly children were still ... agency said, citing Bao Wenhui, the deputy director of the ...
Cached Medicine News:Health News:Steroid Scam: Sylvester Stallone Gets Away With a Light Punishment 2Health News:AIDS Victims, Supporters Gather in Bond of Hope 2Health News:Gilead's AIDS Drug Awaits Patent in India 2Health News:Repetition Is Like Chanting The More It is Heard the More You Believe It 2Health News:My Space Pressured into Sharing Data on Sex Offenders 2
(Date:8/4/2015)... Md. , Aug. 4, 2015 ... drug-free over-the-counter ActiPatch® Musculoskeletal Pain Therapy medical devices, ... users of its ActiPatch 7-day trial device has ... journal Pain Management http://www.futuremedicine.com/doi/full/10.2217/PMT.15.35 .  ... the survey and submitted an assessment.  ...
(Date:8/4/2015)... 4, 2015 Research and Markets ( http://www.researchandmarkets.com/research/nl392k/alcohol ... Ethoxylate Market by Application (Household & Personal Care, Pharmaceutical, ... Forecasts to 2019" report to their offering. ... valued at $5,124.9 million in 2014 and is projected ... 2014 to 2019. The data mentioned in the report ...
(Date:8/4/2015)... Second Quarter 2015 Highlights: ... quarter of 2014 , Net earnings attributable to Team ... after adjustments , Diluted net earnings per share of ... 15.2% to $99.4 million 2015 Outlook: ... of 24.0% to 26.0%; Adjusted EBITDA margin remains between 10.5% ...
Breaking Medicine Technology:BioElectronics' Landmark 5,000+ Chronic Pain Patient Study Published in Pain Management Medical Journal 2Global Alcohol Ethoxylate Market 2015 - Market Trends, Forecasts to 2019 for the $5.1 Billion Industry 2Global Alcohol Ethoxylate Market 2015 - Market Trends, Forecasts to 2019 for the $5.1 Billion Industry 3Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 2Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 3Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 4Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 5Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 6Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 7Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 8Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 9Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 10Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 11Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 12Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 13Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 14Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 15Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 16Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 17Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 18Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 19Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 20Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 21Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 22Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 23Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 24Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 25Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 26Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 27Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 28Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 29Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 30Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 31Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 32Team Health Holdings, Inc. Announces Second Quarter 2015 Financial Results 33
... centrifuge is designed especially for ... cover with safety interlock switch, ... emissions, "hold" position for continuous ... motor, maximum stability and compact, ...
... The Rotanta 460 family ... extraordinary line that meets ... demands. They feature high ... Their state-of-the-art technology and ...
The Spinchron 15 centrifuge provides all the versatility and high capacity needed for today's full-service clinical lab needs. This centrifuge is available in a nonrefrigerated model with a speed up ...
... lens handle lets them hold the ... itself. Lenses and tints are shown ... white with literature holders on each ... black, red, or white marble, gray ...
Medicine Products: