Navigation Links
JCI table of contents: Jan. 25, 2011
Date:1/25/2011

resembling erosive rheumatoid arthritis. Importantly, the disease was initiated by the GGTase-Ideficient macrophages, which hypersecreted inflammatory molecules known as cytokines. As the authors note and Mark Philips, at New York University, New York points out, in an accompanying commentary, these data have important implications for drug development, where GGTase-I inhibitors have been proposed as a strategy to treat inflammatory disorders and are under development as anticancer drugs.

TITLE: Geranylgeranyltransferase type I (GGTase-I) deficiency hyperactivates macrophages and induces erosive arthritis in mice

AUTHOR CONTACT:
Martin O. Bergo
Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Phone: 46.31.342.78.58; Fax: 46.31.82.37.62; E-mail: martin.bergo@wlab.gu.se.

View this article at: http://www.jci.org/articles/view/43758?key=3a26ecf260de7bfbb5ca

ACCOMPANYING COMMENTARY
TITLE: The perplexing case of the geranylgeranyl transferasedeficient mouse

AUTHOR CONTACT:
Mark R. Philips
New York University Cancer Institute, New York, New York, USA.
Phone: 212.263.7404; Fax: 212.263.9210; E-mail: mark.philips@nyumc.org.

View this article at: http://www.jci.org/articles/view/45952?key=84050ca36dfb7be0c5e6


IMMUNOLOGY: More regulators of Th17 immune cell generation

A subset of immune cells known as Th17 cells have an important role in clearing certain bacterial and fungal infections. However, they are also thought to sometimes attack other cells and tissues of the body, causing autoimmune diseases such as multiple sclerosis. Understanding the regulatory pathways underlying the generation of t
'/>"/>

Contact: Ushma Neill
press_releases@the-jci.org
734-546-5241
Journal of Clinical Investigation
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8

Related medicine news :

1. Compound shows promise against intractable heart failure
2. JCI online early table of contents: Feb. 15, 2010
3. Americans Falling Short on Heart-Healthy Fruits and Vegetables
4. Kidneys From Older Donors Suitable for Seniors
5. Protein Sciences Corporation Announces Profitable and Cash Flow Positive Results for 2009 and Management Realignment
6. Angeles Launches New Portable Hot Water Sinks
7. My1Stop.com Expands Into Medical Wristbands Market with Patented LaserBand Printable Wristbands
8. Tips for Safe Charitable Giving in Response to Earthquakes in Chile and Haiti
9. Iridoids in Tahitian Noni Bioactive Beverages™ are Found to be Extremely Stable
10. iTable Debuts at CeBIT 2010 to Revolutionize Your Living Room
11. ONE Launches New Campaign to Empower Women in the Fight Against Poverty and Preventable Disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... 28, 2014 In the healthcare industry, ... practices struggle with: How can the overall quality of ... study of the healthcare industry tackles this question, and ... employee job satisfaction and the quality of patient care. ... found in “ Organizational Factors related to Improving Quality ...
(Date:8/28/2014)... (PRWEB) August 28, 2014 DoctorBase ... and mid-sized healthcare organizations, today announced that it has ... appointment company ZocDoc , to head their sales ... has created a sales management position. , “I’m passionate ... like DoctorBase that already has so much traction and ...
(Date:8/28/2014)... York (PRWEB) August 28, 2014 An unprecedented ... and neck issues, Cloud 9 Spine offers their resources online ... problems can quickly become a brick wall of discouragement as ... a professional opinion, Cloud 9 Spine offers a ... technology merged with human interaction that sets Cloud 9 Spine ...
(Date:8/28/2014)... (PRWEB) August 28, 2014 Top ... many web hosting companies and announces Bluehost, HostMonster ... recommended suppliers for the webmasters worldwide who want ... rates. , As the world’s most popular server-side ... and many other general-purpose programs. It is now ...
(Date:8/28/2014)... Now in its 4th year, Step for ... by two brain aneurysm survivors. The ongoing mission of Step ... to help increase early detection and to help support individuals ... We hope that you will be able to join this ... Annual Step for Hope Run/ Walk on Saturday, September 6, ...
Breaking Medicine News(10 mins):Health News:New Healthcare Study Explores Strategies for Improving Patient Care 2Health News:New Healthcare Study Explores Strategies for Improving Patient Care 3Health News:New Healthcare Study Explores Strategies for Improving Patient Care 4Health News:DoctorBase Hires Josh Angeles as Vice-President of Sales 2Health News:Making Waves on the East Coast, Cloud 9 Spine is Helping Patients Find Appointments With Local Spine Doctors 2Health News:Step for Hope and Raise Brain Aneurysm Awareness 2
... arise sporadically, rather than through inheritance of certain genes, ... allow environmentally triggered mutations to accumulate, according to researchers ... Hospital of UPMC and the University of Pittsburgh Cancer ... online edition of the Proceedings of the National ...
... the emergence of an epidemic of obesity and type 2 ... that may affect the risk of metabolic diseases is especially ... tend to have about 30% lower risk of developing late ... to be at lower risk of developing metabolic syndrome ...
... Reporter , MONDAY, Nov. 29 (HealthDay News) -- The prescription ... study suggests. But one expert was quick to note ... the pain of arthritis, has been linked in some studies ... So it isn,t yet clear that Celebrex (celecoxib) is an ...
... , MONDAY, Nov. 29 (HealthDay News) -- Smoking boosts the ... and those with a genetic risk factor for rheumatoid arthritis ... a new study has found. Researchers evaluated 605 black ... found that those with the disease were slightly more likely ...
... The American College of Physicians (ACP) today is sending ... internists speaking in their own words ( ... Congress to avert the scheduled Medicare Sustainable Growth Rate ... the repeated cycle of cuts. The 3-minute and ...
... the Psychoimmunology Unit at Lund University is presenting these results ... group led by Dr Lena Brundin, which sees inflammation in ... is a new theory that challenges the prevalent view that ... serotonin and noradrenaline. "However, current serotonin-based medication cures far ...
Cached Medicine News:Health News:Sporadic breast cancers start with ineffective DNA repair systems, Pitt researchers find 2Health News:Moderate alcohol consumption lowers the risk of metabolic diseases 2Health News:Celebrex Shows Potential in Preventing Some Skin Cancers: Study 2Health News:Celebrex Shows Potential in Preventing Some Skin Cancers: Study 3Health News:Heavy Smoking May Double Rheumatoid Arthritis Risk in Blacks 2Health News:Internists issue heartfelt plea for Congress to help patients by stopping Medicare SGR cuts 2Health News:Internists issue heartfelt plea for Congress to help patients by stopping Medicare SGR cuts 3Health News:Biological changes in suicidal patients 2
(Date:8/28/2014)... N.Y. , Aug. 28, 2014 ... have entered a partnership to advance an experimental ... myeloma (SMM), an asymptomatic stage of myeloma. ... Program® (TAP), through which LLS forges collaborations with ... faster. OncoPep is developing a ...
(Date:8/28/2014)... 2014  STAAR Surgical Company (NASDAQ: STAA ) ... delivery systems for the eye, today announced that management will ... New York Palace Hotel on Wednesday, September 3 at 7:15 ... President and CEO will offer a general overview of the ... be joined by Steve Brown , CFO, and ...
(Date:8/27/2014)... 28, 2014 China Nepstar Chain Drugstore ... "Company"), a leading retail drugstore chain in China ... today announced its unaudited financial results for the ... HighlightsFor the quarter ended June 30, 2014: , ... compared to RMB638.8 million in the second quarter ...
Breaking Medicine Technology:The Leukemia & Lymphoma Society Provides Equity Financing to OncoPep to Support Clinical Trial for Myeloma Vaccine 2STAAR Surgical To Present At The Baird 2014 Health Care Conference 2China Nepstar Chain Drugstore Ltd. Reports Second Quarter 2014 Financial Results 2China Nepstar Chain Drugstore Ltd. Reports Second Quarter 2014 Financial Results 3China Nepstar Chain Drugstore Ltd. Reports Second Quarter 2014 Financial Results 4China Nepstar Chain Drugstore Ltd. Reports Second Quarter 2014 Financial Results 5China Nepstar Chain Drugstore Ltd. Reports Second Quarter 2014 Financial Results 6China Nepstar Chain Drugstore Ltd. Reports Second Quarter 2014 Financial Results 7China Nepstar Chain Drugstore Ltd. Reports Second Quarter 2014 Financial Results 8China Nepstar Chain Drugstore Ltd. Reports Second Quarter 2014 Financial Results 9China Nepstar Chain Drugstore Ltd. Reports Second Quarter 2014 Financial Results 10China Nepstar Chain Drugstore Ltd. Reports Second Quarter 2014 Financial Results 11
... (Nasdaq: PRGO ; TASE) today announced that it ... foam brought by Stiefel Research Australia Pty. Ltd., a GSK ... in the U. S., a generic version of Men,s Rogaine® ... Rogaine® (Minoxidil) Foam is used to regrow ...
... Informex , the leading meeting place for buyers ... applications, today announced details of its second Latin American Green ... The event will be held in September 2011, with further ... 2011 event follows the success of the inaugural Informex Latin ...
Cached Medicine Technology:Perrigo Announces Settlement of Rogaine® Foam Patent Litigation 2Second Annual Latin America 'Green Exchange Conference' Hosted by Informex Focuses on a Sustainable Future for Chemistry 2Second Annual Latin America 'Green Exchange Conference' Hosted by Informex Focuses on a Sustainable Future for Chemistry 3
Arthrex has the most extensive offering of arthroscopic suture passing instruments,available anywhere in the world. We have speci? cally designed the function of our,instruments to work hand in hand ...
85 right angled suture passer....
The Mini-Revo suture anchor is designed primarily for arthroscopic and open Bankart shoulder repair. Additional applications include other shoulder repair procedures, as well as use in small joints....
... Labral Anchor is an L-PLA anchor ... soft tissue reattachment to bone. The ... bony contour of the glenoid, optimizing ... Osteo Compression (ROC) design to provide ...
Medicine Products: