Navigation Links
JCI table of contents: Jan. 25, 2011
Date:1/25/2011

enn.edu">sryeom@upenn.edu.

View this article at: http://www.jci.org/articles/view/45976?key=0691d06bba3bde5fff57


CARDIOLOGY: Developmental misstep results in extremely fast heartbeat

Wolff-Parkinson-White syndrome is characterized by periods of an extremely fast heartbeat. These occur because of the presence of additional electrical pathways in the heart that cause the bottom chambers of the heart (the ventricles) to contract prematurely. The developmental reasons for premature ventricular contraction (also known as ventricular preexcitation) are not well understood. However, two independent research groups have now identified in mice a new mechanism by which additional electrical pathways in the heart can form, resulting in ventricular preexcitation. Specifically, the data from both groups one led by Jonathan Epstein, at the University of Pennsylvania, Philadelphia; and the other by Vincent Christoffels, at the Academic Medical Center, The Netherlands indicate that additional electrical pathways in the heart form as a result of inappropriate development of a structure in the embryonic heart known as the AV canal.

In an accompanying commentary, Hiroshi Akazawa and Issei Komuro, at the Osaka University Graduate School of Medicine, Japan, discuss the importance of these two papers for understanding the mechanisms of physiologic and pathologic heart development.

TITLE: Notch signaling regulates murine atrioventricular conduction and the formation of accessory pathways

AUTHOR CONTACT:
Jonathan A. Epstein
University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Phone: 215.898.8731; Fax: 215.573.2094; E-mail: epsteinj@mail.med.upenn.edu.

View this article at: http://www.
'/>"/>

Contact: Ushma Neill
press_releases@the-jci.org
734-546-5241
Journal of Clinical Investigation
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8

Related medicine news :

1. Compound shows promise against intractable heart failure
2. JCI online early table of contents: Feb. 15, 2010
3. Americans Falling Short on Heart-Healthy Fruits and Vegetables
4. Kidneys From Older Donors Suitable for Seniors
5. Protein Sciences Corporation Announces Profitable and Cash Flow Positive Results for 2009 and Management Realignment
6. Angeles Launches New Portable Hot Water Sinks
7. My1Stop.com Expands Into Medical Wristbands Market with Patented LaserBand Printable Wristbands
8. Tips for Safe Charitable Giving in Response to Earthquakes in Chile and Haiti
9. Iridoids in Tahitian Noni Bioactive Beverages™ are Found to be Extremely Stable
10. iTable Debuts at CeBIT 2010 to Revolutionize Your Living Room
11. ONE Launches New Campaign to Empower Women in the Fight Against Poverty and Preventable Disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/21/2014)... Market Research Report on ... 2009-2019 is a professional and in-depth market ... 49562-28-9) industry. The report firstly reviews the ... its classification, application and manufacturing technology.The report ... of Fenofibrate (CAS 49562-28-9) listing their product ...
(Date:9/21/2014)... September 21, 2014 An experienced review ... its newest hosting ranking list and announced that FatCow ... VPS hosting suppliers. , There has been a ... demand has resulted in an increase in the number ... different services at very affordable prices. VPS (Virtual Private ...
(Date:9/21/2014)... Md. (PRWEB) September 21, 2014 Faculty and ... with a coed preschool in Owings Mills, Md., kicked off ... with Garmin Vivofit bands. GFS is the first independent school ... taken, calories burned and even sleep patterns— as part of ... Baltimore area running and walking specialty chain. The Vivofit bands ...
(Date:9/20/2014)... 21, 2014 Recently, iFitDress.com, a well-known wedding ... beautiful party dresses . In addition, the company has ... aim of the promotion is to benefit all of its ... its online store now. , Along with beautiful party ... items. It has recently released its new sexy short prom ...
(Date:9/20/2014)... 6 Minutes to Skinny , a ... Ballantyne that is showing men and women of all ages ... body fat using simple 6-minute exercises and easy-to-follow lifestyle tips ... investigative review. , “When it comes to losing body ... out for all people,” reports Michaels. “Metabolism plays a big ...
Breaking Medicine News(10 mins):Health News:Fenofibrate Industry Global and Chinese Analysis for 2014-2019 Now Available at LifeScienceIndustryResearch.com 2Health News:Fenofibrate Industry Global and Chinese Analysis for 2014-2019 Now Available at LifeScienceIndustryResearch.com 3Health News:Fenofibrate Industry Global and Chinese Analysis for 2014-2019 Now Available at LifeScienceIndustryResearch.com 4Health News:Top10BestSEOHosting.com: FatCow, GoDaddy And Bluehost Are The Best VPS Hosting Suppliers 2Health News:Garrison Forest School Leader in Independent School Wellness Programs 2Health News:Beautiful Party Dresses For Autumn Unveiled By iFitDress.com 2Health News:6 Minutes to Skinny: Review Exposes Craig Ballantyne’s Method to Jump Starting the Metabolism and Blasting Away Body Fat in Just 6 Minutes Per Day 2
... phenomenon known as grapheme-color synaesthesia describes individuals who experience ... ordinary letters and digits. A hallmark of synaesthesia ... experiences. That is, most synesthaetes will consistently see ... of these experiences appear to be shared with other ...
... cancer screening tests are more likely to be diagnosed with ... of the Swedish national cervical cancer screening program that will ... the National Cancer Institute . Participation in screening reduces the ... Better follow-up of the women who are screened could further ...
... professors, Helmut Hofer of NYUs Courant Institute of Mathematical ... for Neural Science, have been elected to the National ... , Hofer and Movshon were among the 72 new ... were elected in recognition of their distinguished and continuing ...
... expanded YOU: The Owner,s Manual released today, SAN ... YOU: The Owner,s Manual, Updated and Expanded Edition, by ... The original book,published by HarperCollins in 2005, sold more ... books across all titles in 2005. The new,edition, packed ...
... League (TRL) announced today the sign-up, practice and match,schedules for ... attendance,dates for the three day Glendale Raptor/USA Rugby Youth Academy ... - June 28th, 2008. Practices for,all divisions, ages 5-15, boys, ... 5:00-6:30 pm at Mir Park in Glendale. Matches will be,held ...
... significant efforts to improve access to safe water and sanitation, ... of Nottingham, argues that much more needs to be done. ... the UN definition of what constitutes safe water, a large ... gastroenteritis. , A key United Nations Millennium Development Goal ...
Cached Medicine News:Health News:New research shows consistency in synaesthetic experiences 2Health News:Review of cervical cancer screening program shows effectiveness and room for improvement 2Health News:America's Favorite Doctors Try to Outdo Their Own Blockbuster 2Health News:The Glendale Raptors Set Dates for Youth Rugby League and USA Rugby Youth Academy 2Health News:Safe water? Lessons from Kazakhstan 2
(Date:9/19/2014)... Sept. 19, 2014 "Copay coupons," ... sales of brand drugs among patients with prescription drug ... to a new report  from the Department ... Inspector General (OIG). Federal anti-kickback laws prohibit suppliers ... are subsidized by the federal government. ...
(Date:9/19/2014)... Research and Markets ... of the "Global Gynecological Devices Market ...      (Logo: http://photos.prnewswire.com/prnh/20130307/600769) , ... wide categories based on their operations. These ... different gynecological conditions that affect the female ...
(Date:9/19/2014)... -- 4WEB Medical announces the formal launch of the ... on the market today at this weekend,s American ... Chicago .  The Osteotomy Truss System is a ... 74 size options included in one versatile set. Previously ... to 18 implant sizes, which limited a surgeon,s ability ...
Breaking Medicine Technology:PCMA: New OIG Report Cites Drug Manufacturer "Copay Coupon" Use in Medicare Part D 2Global Gynecological Devices Market 2014-2018: Key Vendors are Bayer, Boston Scientific, CooperSurgical, Ethicon, Hologic, Medtronic, Olympus and Stryker 2Global Gynecological Devices Market 2014-2018: Key Vendors are Bayer, Boston Scientific, CooperSurgical, Ethicon, Hologic, Medtronic, Olympus and Stryker 34WEB Medical Unveils 3D-Printed Osteotomy Truss System 2
... of emission at two different wavelengths (1064 and ... 1064 DW is able to select the delivered ... (with powers selectable among 4 and 100 W) ... 25 W). This second wavelength is very useful ...
Smartepil II is a laser particularly indicated for hair-removal where it has proved to be a valid instrument, even in the treatment of darker phototypes and telangiectasias of the face and legs....
... Tri-Active is the result of ... the combination of three different methods ... to your skin. This treatment is ... of cellulite through the combined action ...
... SmartOffice Plus is a CO2 ... to 25 W. Its functions in ... for surgery requiring extreme laser intervention ... in medical studios, it comes with ...
Medicine Products: