Navigation Links
JCI table of contents: April 25, 2011
Date:4/25/2011

45636?key=c7a74618d3a706d6e2a5

ACCOMPANYING COMMENTARY
TITLE: Fibulin-5: two for the price of one maintaining pelvic support

AUTHOR CONTACT:
Gina M. Northington
University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.
Phone: 215.662.6361; Fax: 215.662.7929; E-mail: gnorthington@obgyn.upenn.edu.

View this article at: http://www.jci.org/articles/view/57438?key=dab0f15181873ab2fbf9


INFECTIOUS DISEASE: Targeting tissue destruction in tuberculosis

Infection with the bacterium Mycobacterium tuberculosis can cause tuberculosis. In most people, however, the bacteria do not cause disease but are sequestered in the lung in walled off compartments known as granulomas. By studying both human samples and mice expressing the human form of the protein MMP-1, a team of researchers, led by Paul Elkington, at Imperial College London, United Kingdom, has now generated data indicating that MMP-1 drives lung tissue destruction in granulomas. The team therefore suggests that targeting MMP-1 might provide a way to limit the damage caused by infection with Mycobacterium tuberculosis. This and other data indicating that MMPs represent viable therapeutic targets to control Mycobacterium tuberculosis infections are discussed in an accompanying commentary by Padmini Salgame, at the University of Medicine and Dentistry of New Jersey, Newark.

TITLE: MMP-1 drives immunopathology in human tuberculosis and transgenic mice

AUTHOR CONTACT:
Paul Elkington
Imperial College London, London, United Kingdom.
Phone: +44.20.8383.2733; Fax: +44.20.8383.3394; E-mail: p.elkington@imperial.ac.uk.

View this article at:

Contact: Karen Honey
press_releases@the-jci.org
734-546-5242
Journal of Clinical Investigation
Source:Eurekalert

Page: 1 2 3 4 5 6

Related medicine news :

1. JCI online early table of contents: April 18, 2011
2. Accountable care organizations have potential to curb costs and improve health care
3. JCI online early table of contents: April 11, 2011
4. Wiley hosts developmental psychology roundtable at SRCD
5. Implantable Device May Lower Tough-to-Treat Hypertension
6. JCI online early table of contents: April 1, 2011
7. Tetanus Still Diagnosed in U.S., Although Its Preventable
8. JCI online early table of contents: March 23, 2011
9. DSF Charitable Foundation gives $3.9M to CMUs Center or Nucleic Acids Science & Technology
10. Gardening linked to increased vegetable consumption in older adults
11. JCI online early table of contents: March 14, 2011
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... Hawley, PA (PRWEB) January 22, 2015 Woodloch ... Pocono Mountains, has been selected by TripAdvisor as the number ... and the 6th best in the world for their annual ... online travel community . The website is home to ...
(Date:1/22/2015)... 23, 2015 Angelweddingdress is a famous wedding ... its customers to follow it on Facebook, Twitter, and Pinterest. ... Day gift. Angelweddingdress draws a lottery every week. , Moreover, ... Feb. 28, 2015. Click Angelweddingdress homepage for more ...
(Date:1/22/2015)... TX (PRWEB) January 22, 2015 A ... issue of experience and person-centeredness in the long-term care ... towards action across the continuum. The paper, “The Power ... Continuum,” engages perspectives and practices of the patient, resident ...
(Date:1/22/2015)... Joan Lunden, award-winning American journalist, beloved television host, ... 32nd Annual Miami Breast Cancer Conference planned and ... , shares that “a fast-growing, virulent” cancer in her ... not followed up her clean mammogram with an ultrasound. ...
(Date:1/22/2015)... 22, 2015 Four years since the release of ... coincided with the marriage of Avasa & Matthew Love – the ... is scheduled for release through White Swan Records on February 24, ... is a sacred path available to all of us to walk ...
Breaking Medicine News(10 mins):Health News:TripAdvisor Names Woodloch Pines Best Hotel for Families in America 2Health News:TripAdvisor Names Woodloch Pines Best Hotel for Families in America 3Health News:Angelweddingdress Invites Its Customers To Follow It On Facebook, Twitter, And Pinterest 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 3Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 2Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 3Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 4Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 5Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 6Health News:THE ROAD by Avasa & Matthew Love -- A New Album 2Health News:THE ROAD by Avasa & Matthew Love -- A New Album 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 4
... San Diego based ... After being the focus of the reality series Addicted to Beauty in the US, television ... the reality “dramedy”, introducing Southern California plastic surgery to a whole new audience. , ... (PRWEB) April 22, 2010 -- San ...
... ... things eco-licious in style, mama, home, news, and food. Greenista.com,s daily emails to their reader,s ... ... ? A Greenista is a fashionista with a green conscience. Just in time for Earth ...
... Philanthropic Donation ... ... in northwest San Diego County will soon have their own Castle of Care™. Sanford ... In partnership with Rady Children’s Hospital-San Diego, the primary care pediatric clinic is made possible ...
... The New Mexico Spa Resort,s Tamaya ... ... & Salon at the Hyatt Regency Tamaya Resort & Spa has recently been named one ... travel magazines. The New Mexico spa resort was ranked as the 11th best resort ...
... ... ... Swimming Resource (ISR, www.infantswim.com ), the safest provider of Self-Rescue swimming lessons for babies ... locations on Oahu, including: Honolulu, Aiea, North Shore, Waipahu and Kailua. Since 2008, local ISR ...
... ... worker safety task force to promote interest of oil rig crews and other maritime industry ... Houston, Texas (PRWEB) ... Mexico once again illustrates the hazardous and sometimes deadly work conditions that maritime workers face ...
Cached Medicine News:Health News:San Diego Plastic Surgery Practice Making a Splash in United Kingdom and Australia 2Health News:San Diego Plastic Surgery Practice Making a Splash in United Kingdom and Australia 3Health News:New Eco Site, Greenista.com, Launches on Earth Day 2Health News:Sanford Health Announces Sanford Children's Clinic in California and Partnership with Rady Children's Hospital-San Diego 2Health News:Sanford Health Announces Sanford Children's Clinic in California and Partnership with Rady Children's Hospital-San Diego 3Health News:Sanford Health Announces Sanford Children's Clinic in California and Partnership with Rady Children's Hospital-San Diego 4Health News:Sanford Health Announces Sanford Children's Clinic in California and Partnership with Rady Children's Hospital-San Diego 5Health News:Leading New Mexico Resort Spa At Hyatt Regency Tamaya Ranked Among The Country's Best By Conde Nast Traveler 2Health News:Leading New Mexico Resort Spa At Hyatt Regency Tamaya Ranked Among The Country's Best By Conde Nast Traveler 3Health News:Infant Swimming Resource Now Has 11 Self-RescueTM Swimming Locations in Hawaii 2Health News:Infant Swimming Resource Now Has 11 Self-RescueTM Swimming Locations in Hawaii 3Health News:Explosion on Gulf Coast Oil Rig Underscores Daily Dangers for Maritime Workers, Say Houston Maritime Injury Lawyers Arnold & Itkin LLP 2
(Date:1/22/2015)...  Profil Institute for Clinical Research, Inc., a clinical research ... a new textbook,  Translational Research Methods for Diabetes, Obesity ... global scientific publisher. The textbook is the ... in early phase clinical studies of new drugs for ...
(Date:1/22/2015)... , Jan. 22, 2015 Research and Markets ... the "Infectious Disease Diagnostics Market by Product, Application, ... report to their offering. , The infectious ... of 7.9% to reach $18,156.2 million by 2019 from ...
(Date:1/22/2015)... Jan. 22, 2015 Research and Markets ( http://www.researchandmarkets.com/research/w25xpc/allergy ... Market by Allergen Source, Product & by End User - ... The global allergy diagnostics market is valued at ... a CAGR of 12.67%, to reach $2,230.72 million by 2019. ...
Breaking Medicine Technology:New Textbook "Translational Research Methods for Diabetes, Obesity and Cardiometabolic Drug Development" Provides Critical Review Of Current And Emerging Clinical Investigation Methods 2New Textbook "Translational Research Methods for Diabetes, Obesity and Cardiometabolic Drug Development" Provides Critical Review Of Current And Emerging Clinical Investigation Methods 3Global Infectious Disease Diagnostics (Instruments, Reagents, Services, Software) Market - Forecast to 2019 2Global Infectious Disease Diagnostics (Instruments, Reagents, Services, Software) Market - Forecast to 2019 3Global Allergy Diagnostics (Immunoassay Analyzer, Luminometer, Assay Kit, Consumables) Market - Forecast to 2019 2Global Allergy Diagnostics (Immunoassay Analyzer, Luminometer, Assay Kit, Consumables) Market - Forecast to 2019 3
... First Presentation of Full Data Set from the TRIUMPH-1 Trial of ... ... SPRING, Md., May 21 United,Therapeutics Corporation (Nasdaq: UTHR ) ... seven presentations concerning,the treatment of pulmonary arterial hypertension (PAH) with treprostinil,were ...
... of Four HUMIRA Patients from CHARM Study in Remission at ... ... 21 Results from an,open-label extension study of two Abbott ... treated with,HUMIRA(R) (adalimumab) achieved long-term clinical remission and clinical,response, respectively, ...
Cached Medicine Technology:Treprostinil Data Presented at American Thoracic Society Conference Demonstrates Significant Clinical Progress in All Four Routes of Administration 2Treprostinil Data Presented at American Thoracic Society Conference Demonstrates Significant Clinical Progress in All Four Routes of Administration 3Treprostinil Data Presented at American Thoracic Society Conference Demonstrates Significant Clinical Progress in All Four Routes of Administration 4Treprostinil Data Presented at American Thoracic Society Conference Demonstrates Significant Clinical Progress in All Four Routes of Administration 5Treprostinil Data Presented at American Thoracic Society Conference Demonstrates Significant Clinical Progress in All Four Routes of Administration 6Abbott Presents Long-Term Data From Extension Study Showing Adult Crohn's Patients Treated With HUMIRA(R) (Adalimumab) Maintained Remission 2Abbott Presents Long-Term Data From Extension Study Showing Adult Crohn's Patients Treated With HUMIRA(R) (Adalimumab) Maintained Remission 3Abbott Presents Long-Term Data From Extension Study Showing Adult Crohn's Patients Treated With HUMIRA(R) (Adalimumab) Maintained Remission 4Abbott Presents Long-Term Data From Extension Study Showing Adult Crohn's Patients Treated With HUMIRA(R) (Adalimumab) Maintained Remission 5Abbott Presents Long-Term Data From Extension Study Showing Adult Crohn's Patients Treated With HUMIRA(R) (Adalimumab) Maintained Remission 6Abbott Presents Long-Term Data From Extension Study Showing Adult Crohn's Patients Treated With HUMIRA(R) (Adalimumab) Maintained Remission 7
The reliable and easy-to-use 3800 pulse oximeter is now more advanced - featuring TruTrak+ technology, the proprietary clinical motion algorithm from Datex+-Ohmeda....
... Tabletop/Portable Digital Pulse Oximeter provides ... patient monitering. From transport applications ... has earned the confidence of ... recognized for its reliability, durability ...
... Richard-Allan Scientific Resolve Immersion Oil ... allows light transmission throughout most of ... in both low and high viscosity, ... a refractive index of 1.5150. Resolve ...
Immersion Oil, 1,250 cs...
Medicine Products: