Navigation Links
JCI online early table of contents: Sept. 19, 2011
Date:9/19/2011

to individuals with cancer.

TITLE: IL-6 trans-signaling licenses mouse and human tumor microvascular gateways for trafficking of cytotoxic T cells

AUTHOR CONTACT:
Sharon S. Evans
Roswell Park Cancer Institute, Buffalo, New York, USA.
Phone: 716.845.3421; Fax: 716.845.1322; E-mail: sharon.evans@roswellpark.org.

View this article at: http://www.jci.org/articles/view/44952?key=7389af36312eccfd1360


ONCOLOGY: Removing support for cancer cells

Pancreatic cancer is one of the most lethal cancers, with a 5-year survival rate of less than 5%. A team of researchers, led by Hideaki Ijichi, at the University of Tokyo, Japan, has now identified a new approach to reduce tumor progression in a mouse model of pancreatic ductal adenocarcinoma (PDAC), the most common form of pancreatic cancer in humans. Specifically, the team found that inhibiting the molecule Cxcr2 on the surface of stromal cells supporting the cancer cells reduced tumor progression and improved survival. The team therefore suggests that targeting tumor stromal cells, in particular by inhibiting Cxcr2, could provide a new approach for treating individuals with PDAC.

TITLE: Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma

AUTHOR CONTACT:
Hideaki Ijichi
Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
Phone: 81.3.3815.544; Fax: 81.3.3814.0021; E-mail: hideijichi-gi@umin.ac.jp.

View this article at: http://www.jci.org/articles/view/42754?key=fb76126c4127b90a1e04


HEMATOLOGY: Triggering disease in a model of peripheral T cell lymphoma

'/>"/>

Contact: Karen Honey
press_releases@the-jci.org
734-546-5242
Journal of Clinical Investigation
Source:Eurekalert

Page: 1 2 3 4 5 6 7

Related medicine news :

1. JCI online early table of contents: Sept. 12, 2011
2. 2011 European Muldisciplinary Cancer Congress abstracts online Sept. 12
3. JCI online early table of contents: Sept. 1, 2011
4. Illegal Online Pharmacies Prey on Consumers
5. Women, Whites Most Likely to Seek Health Info Online: Survey
6. JCI online early table of contents: July 18, 2011
7. JCI online early table of contents: July 11, 2011
8. JCI online early table of contents: July 1, 2011
9. JCI online early table of contents: June 13, 2011
10. NYU Langone rheumatologists share insight with online RA community
11. JCI online early table of contents: June 1, 2011
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... (PRWEB) October 22, 2014 Healthcare ... completing their continuing education at home or on-the-go ... access to 20 brand new, premium Seminar-on-Demand CE ... catalog of over 2,000 hours of ... customize their educational experience. With such a diverse ...
(Date:10/22/2014)... Lintelus, Inc., an event software provider, announced ... will be speaking on the subject of “Event Technology ... 28, at the Holiday Inn in New York City. ... as a Tech Demo at 12:45pm, to educate event ... engaging event experience. , The Annual Meetings Technology Expo ...
(Date:10/22/2014)... HealthDay Reporter , TUESDAY, Oct. 21, 2014 (HealthDay ... be showing a genetic propensity for obesity as toddlers, a ... linked to increased body fat, but the same genes in ... researchers said. At 1 year, kids with these genes ... however, these genes were linked to excessive weight gain, the ...
(Date:10/22/2014)... Tara Haelle HealthDay Reporter ... among young adult men may lead to increased blood pressure, ... cause a similar rise in blood pressure for young adult ... when young adult women drank lightly or moderately, their risk ... found. "This finding parallels studies in older adult men ...
(Date:10/22/2014)... Thompson HealthDay Reporter , MONDAY, ... Monday officially tightened guidelines for health workers treating Ebola patients, ... use of a respirator at all times. The U.S. ... tougher rules after two Dallas nurses contracted Ebola while caring ... Liberian national Thomas Eric Duncan. Nina Pham is currently being ...
Breaking Medicine News(10 mins):Health News:Top Provider of Continuing Education at Home Releases 20 New Online Courses 2Health News:Jay Cormier, Sr. Vice President of Sales for Lintelus, Speaks about Event Technology Integration at Meetings Technology Expo in NYC 2Health News:Tall, Heavy 1-Year-Olds May Be at Risk for Obesity Later, Study Finds 2Health News:Binge Drinking May Boost Blood Pressure in Young Men 2Health News:Binge Drinking May Boost Blood Pressure in Young Men 3Health News:Binge Drinking May Boost Blood Pressure in Young Men 4Health News:CDC Tightens Rules on Caring for Ebola Patients 2Health News:CDC Tightens Rules on Caring for Ebola Patients 3
... behind her dramatic weight loss over the past few months, and ... ,Jolie told reporters at the New York premiere ... lost weight is because shes not only still grieving over the ... in January, but also busy running around four young kids. ...
... some extra sleep before a big game could improve ... Cheri Mah and colleagues at Stanford University observed six ... were told to maintain their usual sleeping habits for ... were instructed to get as much extra sleep as ...
... study has found that obesity, high blood pressure, high cholesterol, ... age group of 18 24. , The ... Lofgren, Joanne Burke, Ruth Reilly and Jesse Morrell, at the ... study, researchers collected data from more than 800 undergraduates enrolled ...
... Salk Institute for Biological Studies have found in a study ... in everyday life, may contribute to the accumulation of ... Alzheimers disease. ,The researchers say that while aging ... number of studies have pointed to stress as a contributing ...
... are affected by scorching temperatures . ,Dogs in Jaipur ... canines being treated at veterinary hospitals everyday. ,Veterinarians ... don't have any sweat glands to keep cool. The sick ... treatments to bring their body temperature to normal. ...
... could save her so much time and money. But after a ... Africa's largest slum, she realized it could. ,With ... that uses human waste to produce gas to burn to heat ... ,"At first I thought it was a very strange idea - ...
Cached Medicine News:Health News:Emotional Stress Could Be a Factor in Causing Alzheimers: Study 2Health News:Bio-latrine Cleans Up Kenyan Slum and the Environment 2Health News:Bio-latrine Cleans Up Kenyan Slum and the Environment 3
(Date:10/20/2014)... -- Indianapolis interventional medical device maker NICO Corporation ... visualization leader Synaptive Medical announced today ... that they have joined forces to integrate their ... the first of its kind and will make ... BrainPath® interventional access technology and Synaptive,s BrightMatter™ real-time ...
(Date:10/20/2014)...  ResMed (NYSE: RMD ) today ... program, a comprehensive suite of software and service ... health care providers. ResMed Data ... information. It integrates valuable sleep and respiratory treatment ... platforms with customers, in-house or third-party electronic health ...
(Date:10/20/2014)... BioNano Genomics announced today achievement of a major milestone ... at 30X depth, sufficient for a genome map, in 24 ... and demonstrated for the IrysChip TM V2, the high-throughput ... will be rolled out to BioNano,s collaborators and customers over ... at the American Society for Human Genetics (ASHG) 2014 ...
Breaking Medicine Technology:Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 2Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 3Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 4Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 5ResMed Launches ResMed Data Exchange 2BioNano Genomics Announces One Human : One Chip : One Day 2BioNano Genomics Announces One Human : One Chip : One Day 3
... (NYSE: AZN ) announced today that the ... complete response letter (CRL) for the New Drug Application ... In the CRL, the FDA requested additional ... request that additional studies, including clinical studies, be conducted ...
... 2010 Insmed Incorporated (Nasdaq CM: INSM), a biopharmaceutical company, ... 16, 2010, from The NASDAQ Stock Market, notifying Insmed that ... until June 13, 2011, to regain compliance with the $1.00 ... The NASDAQ Capital Market, as set forth in NASDAQ Listing ...
Cached Medicine Technology:AstraZeneca Receives Complete Response Letter From US FDA For BRILINTA™ (Ticagrelor Tablets) 2NASDAQ Grants Insmed Incorporated 180-Day Extension to Regain Compliance with Minimum Bid Price Rule 2
Binocular indirect ophthalmic lenses. General diagnosis & treatment....
... Volk's super ... biomicroscopy lenses. Examination ... Provide unprecedented fundus ... addressing maximum potential ...
... series slit lamp biomicroscopy ... of the posterior pole. ... capability, specifically addressing maximum ... fundus image resolution & ...
Volk indirect lenses. High magnification views of the posterior pole....
Medicine Products: