Navigation Links
JCI online early table of contents: Sept. 19, 2011
Date:9/19/2011

atening condition. The most common cause of bacterial meningitis is Streptococcus pneumoniae, a condition known as pneumococcal meningitis. An inflammatory cascade known as the complement system has been implicated as a modulator of the severity of pneumococcal meningitis in animal models. A team of researchers, led by Diederik van de Beek, at Academic Medical Center, the Netherlands, has now identified a specific variant in the gene that templates the protein complement component 5 (C5) as being associated with poor outcome in individuals with bacterial meningitis. Further analysis in mice led the team to suggest that using immune molecules known as antibodies that target C5 could prove useful as a component of therapy for pneumococcal meningitis.

TITLE: Complement component 5 in humans and mice with pneumococcal meningitis

AUTHOR CONTACT:
Diederik van de Beek
Academic Medical Center, Amsterdam, , NLD
Phone: +31 20 5664862; Fax: ; E-mail: d.vandebeek@amc.uva.nl

View this article at: http://www.jci.org/articles/view/57522?key=9cec4eac0c9e957f0575

TUMOR IMMUNOLOGY: Putting the heat on tumors

Immune cells have a key role in regulating tumor formation and progression some (such as CD8+ T cells) are key to restraining tumor formation and progression, while others actually promote these events. A team of researchers, led by Sharon Evans, at Roswell Park Cancer Institute, Buffalo, has now identified a way to enhance the movement of antitumor CD8+ T cells into tumors in mice. Specifically, the team defined a mechanism by which systemic thermal therapy (whereby the core temperature of the mice is elevated to 39.5C 0.5C for 6 hours) supported enhanced movement of CD8+ T cells into tumors. The hope is that these data can be exploited to create a therapeutic approach beneficial
'/>"/>

Contact: Karen Honey
press_releases@the-jci.org
734-546-5242
Journal of Clinical Investigation
Source:Eurekalert

0

GOOD

Page: 1 2 3 4 5 6 7

Related medicine news :

1. JCI online early table of contents: Sept. 12, 2011
2. 2011 European Muldisciplinary Cancer Congress abstracts online Sept. 12
3. JCI online early table of contents: Sept. 1, 2011
4. Illegal Online Pharmacies Prey on Consumers
5. Women, Whites Most Likely to Seek Health Info Online: Survey
6. JCI online early table of contents: July 18, 2011
7. JCI online early table of contents: July 11, 2011
8. JCI online early table of contents: July 1, 2011
9. JCI online early table of contents: June 13, 2011
10. NYU Langone rheumatologists share insight with online RA community
11. JCI online early table of contents: June 1, 2011
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/25/2013)... IBISWorld estimates that revenue for the ... rate of 28.7% to $1.0 billion in the five years ... and 2008, no new cell therapy products were introduced, according ... during that period. In the years since, however, the Food ... factor contributed to the industry's fast growth during the five ...
(Date:5/25/2013)... Virginia (PRWEB) May 25, 2013 Superior ... that relieves pain in seconds for arthritis, tendinitis and ... in alternative pain relief products announced a magnetic ... The magnetic bracelet for pain relief is demonstrated at ... pain uses 5400 Gauss magnets and has customers often ...
(Date:5/25/2013)... AdvantaClean of Pikes Peak recently opened and ... healthy home and business in Colorado Springs and surrounding ... inspections, mold testing, mold removal , air ... , With over 120 offices nationwide, AdvantaClean is a ... full suite of services for commercial, institutional, and governmental ...
(Date:5/24/2013)... myMEDholiday.com, a popular medical tourism portal which includes an ... travel destinations in Asia, has added a helpful and ... safe and successful trip for anyone planning a healthcare ... cost-savings, how to find the appropriate doctors and facilities, ... essential advice. , A top-level marketing representative at the ...
(Date:5/24/2013)... Atlanta, GA (PRWEB) May 24, 2013 Before you ... a cup of coffee with Kathie Lee Gifford and Hoda Kotb ... http://www.digitwirl.com , will show cool tech ideas to Kathie Lee and ... Kyodo America honors our brave men and women in the military ... get ready for the BBQ, spend time with friends and family ...
Breaking Medicine News(10 mins):Health News:Slow Healing: Cell Therapy in the US Industry Market Research Report Now Available from IBISWorld 2Health News:Slow Healing: Cell Therapy in the US Industry Market Research Report Now Available from IBISWorld 3Health News:Magnetic bracelet relieves pain in seconds announces Superior Magnetics 2Health News:Grand Opening! AdvantaClean of Pikes Peak is Proud to Announce Water Damage Restoration, Mold Removal and Air Duct Cleaning Services to the Colorado Springs Area 2Health News:Grand Opening! AdvantaClean of Pikes Peak is Proud to Announce Water Damage Restoration, Mold Removal and Air Duct Cleaning Services to the Colorado Springs Area 3Health News:Grand Opening! AdvantaClean of Pikes Peak is Proud to Announce Water Damage Restoration, Mold Removal and Air Duct Cleaning Services to the Colorado Springs Area 4Health News:myMEDholiday.com Introduces International Patient Guide to Assist People Planning Treatment Abroad 2Health News:LawnBott® Visits the Today Show with Kathie Lee and Hoda 2
... the time in emergency rooms , , TUESDAY, Dec. 18 (HealthDay ... someone is having a heart attack, they are mistaken 9.2 ... that minutes matter with these patients and doctors have to ... say researchers from the Minneapolis Heart Institute Foundation. , "Our ...
... three and older in the United States would carry ... the 2008 University of Louisville Grawemeyer Award in Education. ... nations young children, fill a gap for working families, ... boost the economy, award winners Edward Zigler, Walter Gilliam ...
... led by Mayo Clinic have designed a technique that uses ... cells that spread from primary tumors to other parts of ... shows that this technology could be the basis for a ... appeared in the Dec. 9 online issue of Nature Medicine. ...
... inexpensive infection control measures, hospitals around the world could prevent ... TB), according to a new study in The Lancet by ... Wings for its ability to spread and kill rapidly, XDR ... identified in all regions of the world, including the United ...
... for patients with spinal cord injuries can stimulate ... compensatory changes in the brain, say Canadian researchers. ... function and the ability to walk. , A ... the remarkable benefits of rehabilitation training after a ...
... remains America,s No. 1 killer, AHA says , , TUESDAY, ... death rates in the United States are declining, the ... the nation, according to the American Heart Association. , ... for many people, according to the American Heart Association,s ...
Cached Medicine News:Health News:Diagnosis of Heart Attack Can Be Wrong 2Health News:Researchers train the immune system to deliver virus that destroys cancer in lab models 2Health News:Researchers train the immune system to deliver virus that destroys cancer in lab models 3Health News:Simple strategy could prevent half of deadly tuberculosis infections 2Health News:Intensive training post-spinal cord injury can stimulate repair in brain and spinal cord 2Health News:U.S. Heart Disease Death Rates Falling 2Health News:U.S. Heart Disease Death Rates Falling 3
(Date:5/23/2013)... JERUSALEM , May 23, 2013  Hadasit Bio-Holdings ... portfolio of biotech companies, based on intellectual property ... Israel ,s foremost medical research center, ... Neurosciences Ltd., received significant funding from the Israeli ... Chief Scientist (OCS) to support product development and ...
(Date:5/23/2013)... -- Texas, premier physician associations today announced the establishment of ... need to provide demonstrably better and more efficient patient ... "I am confident the Physician Services Organization for ... Stephen L. Brotherton , MD, president of the ... doctors are determined to make health care better and ...
(Date:5/23/2013)... , May 23, 2013  Net Medical Xpress ... telemedicine market, announced today the company has signed a ... staffing company based in Huntsville, AL ... specializes in the staffing and recruitment of telemedicine physicians. ... of the final agreement, which is expected by June ...
Breaking Medicine Technology:Hadasit Bio-Holdings Ltd. Portfolio Company - Cell Cure Neurosciences Ltd. Received Additional Government Support 2TMA Launches Physician Services Organization for Patient Care 2TMA Launches Physician Services Organization for Patient Care 3TMA Launches Physician Services Organization for Patient Care 4Net Medical Xpress Announces Acquisition of Telemedicine Staffing Company 2Net Medical Xpress Announces Acquisition of Telemedicine Staffing Company 3
... , , , , WALTHAM, Mass., Dec. ... and advisory firms for pharmaceutical and healthcare issues, finds that ... efficacy and side-effect profile, are cited most frequently by surveyed ... non-small-cell lung cancer treatment in Germany, France, Italy, Spain and ...
... HUNTINGTON BEACH, California and AMSTERDAM, December 17 ,Agendia, a ... US Food and Drug Administration (FDA) cleared its MammaPrint ... only FDA-cleared,breast cancer recurrence test available to patients and ... four clearances for MammaPrint, covering,all aspects of this important ...
Cached Medicine Technology:Surveyed European Oncologists Cite Cost Most Frequently as the Factor Preventing Their Use of Avastin for Non-Small-Cell Lung Cancer 2Surveyed European Oncologists Cite Cost Most Frequently as the Factor Preventing Their Use of Avastin for Non-Small-Cell Lung Cancer 3FDA Broadens Clearance for Agendia's MammaPrint(R) 2
Circular Spine Retractor System for microsurgical interventions in the lumbar and cervical spine region....
... also known as BMP-7, is a member of ... Bone Morphogenetic Proteins. OP-1 Implant is known to ... mature skeletal systems. The FDA approved OP-1 Implant ... 2001. OP-1 Implant is now available across the ...
... Connect allografts are dense ... anterior cortical face providing structural ... for rapid healing. These allografts ... Non-Lordotic designs. Connect allografts are ...
... maxillo-facial and cranial surgery are characterized by ... for the most varied of applications. Tailor-made ... that the system is easy to implement ... from titanium. Specially designed instruments for drilling, ...
Medicine Products: