Navigation Links
JCI online early table of contents: Sept. 19, 2011
Date:9/19/2011

atening condition. The most common cause of bacterial meningitis is Streptococcus pneumoniae, a condition known as pneumococcal meningitis. An inflammatory cascade known as the complement system has been implicated as a modulator of the severity of pneumococcal meningitis in animal models. A team of researchers, led by Diederik van de Beek, at Academic Medical Center, the Netherlands, has now identified a specific variant in the gene that templates the protein complement component 5 (C5) as being associated with poor outcome in individuals with bacterial meningitis. Further analysis in mice led the team to suggest that using immune molecules known as antibodies that target C5 could prove useful as a component of therapy for pneumococcal meningitis.

TITLE: Complement component 5 in humans and mice with pneumococcal meningitis

AUTHOR CONTACT:
Diederik van de Beek
Academic Medical Center, Amsterdam, , NLD
Phone: +31 20 5664862; Fax: ; E-mail: d.vandebeek@amc.uva.nl

View this article at: http://www.jci.org/articles/view/57522?key=9cec4eac0c9e957f0575


TUMOR IMMUNOLOGY: Putting the heat on tumors

Immune cells have a key role in regulating tumor formation and progression some (such as CD8+ T cells) are key to restraining tumor formation and progression, while others actually promote these events. A team of researchers, led by Sharon Evans, at Roswell Park Cancer Institute, Buffalo, has now identified a way to enhance the movement of antitumor CD8+ T cells into tumors in mice. Specifically, the team defined a mechanism by which systemic thermal therapy (whereby the core temperature of the mice is elevated to 39.5C 0.5C for 6 hours) supported enhanced movement of CD8+ T cells into tumors. The hope is that these data can be exploited to create a therapeutic approach beneficial
'/>"/>

Contact: Karen Honey
press_releases@the-jci.org
734-546-5242
Journal of Clinical Investigation
Source:Eurekalert

Page: 1 2 3 4 5 6 7

Related medicine news :

1. JCI online early table of contents: Sept. 12, 2011
2. 2011 European Muldisciplinary Cancer Congress abstracts online Sept. 12
3. JCI online early table of contents: Sept. 1, 2011
4. Illegal Online Pharmacies Prey on Consumers
5. Women, Whites Most Likely to Seek Health Info Online: Survey
6. JCI online early table of contents: July 18, 2011
7. JCI online early table of contents: July 11, 2011
8. JCI online early table of contents: July 1, 2011
9. JCI online early table of contents: June 13, 2011
10. NYU Langone rheumatologists share insight with online RA community
11. JCI online early table of contents: June 1, 2011
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/23/2014)... “BlackVue” was featured on NewsWatch as ... features the latest and coolest technology products available to ... NewsWatch, conducted the product review and shared with viewers ... in the car camera industry. , The need for ... hard to find the one that’s right per consumer, ...
(Date:11/23/2014)... Columbus, OH (PRWEB) November 23, 2014 ... claims on behalf of Ohio and West Virginia residents ... and other health disorders due to drinking C8 ... Plant In Parkersburg, West Virginia. According to the C8 ... because they either worked or lived in at least ...
(Date:11/22/2014)... Every year AlignLife clinics nationwide team together to ... in the Greenville, SC area in 2014 and has ... Simpsonville will be partnering with the 5 other ... Drive. These six offices came together to decide on ... toy drive. With so many amazing organizations to choose ...
(Date:11/22/2014)... 2014 PrettyTailor , an outstanding ... new big promotion. Customers can buy new dresses at ... can visit its website. , As a matter of ... dresses. It mainly provides four types of wedding outfits, ... flower girl dresses. It also provides a variety of ...
(Date:11/22/2014)... Recently, Locks-Magnetic.com , one of ... promotion of mag locks for glass doors online. In ... on these fresh products. Customers can get more information ... doors are in excellent performance. Customers who want to ... soon as possible. They also can enjoy the ...
Breaking Medicine News(10 mins):Health News:A Leader in Front and Rear Facing In-Car Cameras was Featured on NewsWatch Television on October 30, 2014 2Health News:40 C8 Lawsuit Claims Filed By Wright & Schulte LLC Alleged Serious Illness Due To C8 Contaminated Water In Ohio And West Virginia 2Health News:40 C8 Lawsuit Claims Filed By Wright & Schulte LLC Alleged Serious Illness Due To C8 Contaminated Water In Ohio And West Virginia 3Health News:40 C8 Lawsuit Claims Filed By Wright & Schulte LLC Alleged Serious Illness Due To C8 Contaminated Water In Ohio And West Virginia 4Health News:Greenville Area AlignLife Offices Join Together for a Local Toy Drive 2Health News:Customers Are Welcome to Shop at PrettyTailor.com 2Health News:Discounted Mag Locks for Glass Doors Revealed by Locks-Magnetic.com 2
... To The Editor: Recent deaths of consumers ... shellfish should remind people with certain pre-existing,conditions of ... warm weather when waters in the Gulf of ... vulnificus bacteria., Vibrio vulnificus is a naturally ...
... Incorporated (NASDAQ: TOMO) announced today that Grupo ... symposium on the clinical use of the ... and stereotactic body radiation therapy (SBRT). Symposium ... for stereotactic procedures with respect to dose ...
... HIV Positive Orphaned Muppet Cheers Soweto Hospice Pediatric ... from the,U.S. Agency for International Development (USAID) and ... Relief (PEPFAR) and other groups,Soweto Hospice has developed ... specialty care and reduce suffering endured by youngsters ...
... in time to help prevent a catastrophe of epic proportions is Get off ... Care, NEW YORK, Oct. 15 , "Dr. Potarazu,s book is both compelling ... transparent costs, and integrating social networking, can truly,revolutionize, ... to one that works.", ...
... 15 Foresight Corporation is pleased,to announce ... joined the,company,s Development division as Senior Solutions ... In this role, she will work ... design new technical solutions, serve as a ...
... Petrulis, MD, FACP, will discuss current trends in care ... ... 15 Alice Stollenwerk Petrulis,MD, FACP, KePRO,s Chief Medical Officer, will ... Solutions, national,conference. On Wednesday, October 22, Dr. Petrulis will present, Care,Management: ...
Cached Medicine News:Health News:Important Health Issue From Be Oyster Aware 2Health News: Grupo IMO Hosts Symposium on Use of TomoTherapy for Stereotactic Radiosurgery and Stereotactic Body Radiation Procedures : Experts Detail HiArt Platform Advantages for Treatment of Brain, Lung, Pancreatic and Metastatic Cancers 2Health News: Grupo IMO Hosts Symposium on Use of TomoTherapy for Stereotactic Radiosurgery and Stereotactic Body Radiation Procedures : Experts Detail HiArt Platform Advantages for Treatment of Brain, Lung, Pancreatic and Metastatic Cancers 3Health News:Children with Life-Threatening Illnesses Receive Hospice Care 2Health News:With the Economy of the United States at a Turning Point, Health Care Could Be Our Next Serious Crisis ... 2Health News:Debra Strickland joins Foresight Corporation in time for HIPAA 5010 Mandate 2Health News:KePRO's Chief Medical Officer to Present and Participate in Physician Roundtable at McKesson Health Solutions Conference 2
(Date:11/21/2014)... MONTREAL , 21. November 2014 ... hat heute bekannt gegeben, dass ... – EMA) die Kennzeichnung als Orphan-Medizinprodukt ... Produktkandidat des Unternehmens zur Behandlung von ... eine seltene, stark beeinträchtigende genetische Krankheit, ...
(Date:11/21/2014)... 20, 2014  Edwards Lifesciences Corporation (NYSE: ... heart valves and hemodynamic monitoring, announced today that it ... support a strong launch of Edwards Lifesciences Foundation,s new ... improve the global communities where its employees live and ... giving will exceed $8 million, including more than $7 ...
(Date:11/21/2014)... BRYDGES, Ontario , Nov. 20, 2014 /PRNewswire/ ... monitor mounting solutions and reading room environment guidance, ... their newest musculoskeletal radiology reading room, which may ... room designs at Penn Medicine. ... by the American College of Radiology,s Imaging 3.0 ...
Breaking Medicine Technology:Clementia Pharmaceuticals erhält EMA-Kennzeichnung als Orphan-Medizin für Palovarotene zur Behandlung von Fibrodysplasia ossificans progressiva 2Clementia Pharmaceuticals erhält EMA-Kennzeichnung als Orphan-Medizin für Palovarotene zur Behandlung von Fibrodysplasia ossificans progressiva 3Edwards Lifesciences Increases Charitable Giving In 2014 To Support Launch Of Every Heartbeat Matters 2RedRick Technologies Helps Penn Radiology Implement New Radiology Reading Room Concepts 2RedRick Technologies Helps Penn Radiology Implement New Radiology Reading Room Concepts 3
... TARRYTOWN, N.Y., April 18, 2012 Bayer HealthCare today ... has cleared its CONTOUR® Next EZ, a new blood ... States.  CONTOUR Next EZ includes an easy-to-use meter and ... new BGM system is being introduced on a market-by-market ...
... launches their Latching Micro-D™ connectors with a new ... quick cable connections to rack and panel equipment.  ... weight, the new latching Micro-D™ connectors, at .050" ... including pull tests that exceeds 100 pound pull ...
Cached Medicine Technology:U.S. FDA Clears Bayer HealthCare's CONTOUR® Next EZ Blood Glucose Monitoring System 2U.S. FDA Clears Bayer HealthCare's CONTOUR® Next EZ Blood Glucose Monitoring System 3Omnetics Launches Panel Mounted Latching Micro-D™ Connectors 2
... VasoSeal VHD was the ... stop bleeding after diagnostic ... radiology procedures. It is ... device approved for immediate ...
... VasoSeal VHD was the ... stop bleeding after diagnostic ... radiology procedures. It is ... device approved for immediate ...
InterVascular HemaCarotid Patch product line offers the vascular surgeon a complete range of knitted, collagen coated patches in a wide range of sizes for carotid endarterectomy and angioplasty witho...
The VasoSeal Low Profile device is designed for smaller sheath angiography procedures. VasoSeal Low Profile. Seal your arterial punctures with confidence....
Medicine Products: