Navigation Links
JCI online early table of contents: Sept. 19, 2011
Date:9/19/2011

atening condition. The most common cause of bacterial meningitis is Streptococcus pneumoniae, a condition known as pneumococcal meningitis. An inflammatory cascade known as the complement system has been implicated as a modulator of the severity of pneumococcal meningitis in animal models. A team of researchers, led by Diederik van de Beek, at Academic Medical Center, the Netherlands, has now identified a specific variant in the gene that templates the protein complement component 5 (C5) as being associated with poor outcome in individuals with bacterial meningitis. Further analysis in mice led the team to suggest that using immune molecules known as antibodies that target C5 could prove useful as a component of therapy for pneumococcal meningitis.

TITLE: Complement component 5 in humans and mice with pneumococcal meningitis

AUTHOR CONTACT:
Diederik van de Beek
Academic Medical Center, Amsterdam, , NLD
Phone: +31 20 5664862; Fax: ; E-mail: d.vandebeek@amc.uva.nl

View this article at: http://www.jci.org/articles/view/57522?key=9cec4eac0c9e957f0575


TUMOR IMMUNOLOGY: Putting the heat on tumors

Immune cells have a key role in regulating tumor formation and progression some (such as CD8+ T cells) are key to restraining tumor formation and progression, while others actually promote these events. A team of researchers, led by Sharon Evans, at Roswell Park Cancer Institute, Buffalo, has now identified a way to enhance the movement of antitumor CD8+ T cells into tumors in mice. Specifically, the team defined a mechanism by which systemic thermal therapy (whereby the core temperature of the mice is elevated to 39.5C 0.5C for 6 hours) supported enhanced movement of CD8+ T cells into tumors. The hope is that these data can be exploited to create a therapeutic approach beneficial
'/>"/>

Contact: Karen Honey
press_releases@the-jci.org
734-546-5242
Journal of Clinical Investigation
Source:Eurekalert

Page: 1 2 3 4 5 6 7

Related medicine news :

1. JCI online early table of contents: Sept. 12, 2011
2. 2011 European Muldisciplinary Cancer Congress abstracts online Sept. 12
3. JCI online early table of contents: Sept. 1, 2011
4. Illegal Online Pharmacies Prey on Consumers
5. Women, Whites Most Likely to Seek Health Info Online: Survey
6. JCI online early table of contents: July 18, 2011
7. JCI online early table of contents: July 11, 2011
8. JCI online early table of contents: July 1, 2011
9. JCI online early table of contents: June 13, 2011
10. NYU Langone rheumatologists share insight with online RA community
11. JCI online early table of contents: June 1, 2011
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2014)... recipients of living donor kidney transplants receive steady ... to be monitored. To make follow-up care more ... (Nasdaq: WAG) are collaborating to launch the first ... testing at no charge to living kidney donors. ... tests redeemable at more than 4,500 Walgreens pharmacies ...
(Date:7/29/2014)... A team of scientists, led by Western University ... a blood test for Alzheimer’s disease risk that may ... disease interventions, according to an article published July 29, ... study represents one of several pieces that have locked ... years,” Ethell said. , The study, “Women with the ...
(Date:7/29/2014)... Beach, Florida (PRWEB) July 29, 2014 Child ... scholarship for law students this week. The scholarship will help ... abused children and their families. , Steinger, Iscoe and Greene ... abuse, and want tomorrow’s attorneys to do the same. More ... each year according to the nonprofit Childhelp (retrieved ...
(Date:7/29/2014)... The report, “Heat Transfer Fluids Market by Type (Mineral ... Others), by Application (Oil & Gas, Chemical, CSP, Manufacturing ... Forecasts to 2019” defines and segments the global heat ... the global consumption in terms of volume and value. ... through 199 page sand in-depth TOC on"Heat Transfer Fluids ...
(Date:7/29/2014)... A new 3-part video series: The Cost/Benefit of ... Angiography and Interventions (SCAI) Scientific Sessions in Las Vegas, ... the benefits of ACE accreditation and the cost/benefit of ... from the perspective of clinicians who have worked with ... RN, Director of Cardiac and Interventional Services at Baptist ...
Breaking Medicine News(10 mins):Health News:Caring for donors 2Health News:Caring for donors 3Health News:Professor Develops Blood Test for Alzheimer’s Disease Risk 2Health News:Steinger, Iscoe & Greene Offers Child Advocate Scholarship 2Health News:Heat Transfer Fluids Market Expected to Grow 641,218.19 Tons by 2019 – New Report by MarketsandMarkets 2Health News:Heat Transfer Fluids Market Expected to Grow 641,218.19 Tons by 2019 – New Report by MarketsandMarkets 3Health News:Heat Transfer Fluids Market Expected to Grow 641,218.19 Tons by 2019 – New Report by MarketsandMarkets 4Health News:Accreditation for Cardiovascular Excellence (ACE) Launches 3-Part Video Series: The Cost/Benefit of ACE Accreditation; ProMedica Toledo Hospital Achieves Accreditation 2Health News:Accreditation for Cardiovascular Excellence (ACE) Launches 3-Part Video Series: The Cost/Benefit of ACE Accreditation; ProMedica Toledo Hospital Achieves Accreditation 3
... prostatectomy, MR imaging plays an important role in determining if ... it has spread beyond the capsule, according to a study ... CA. , The study included a review of ... prostatectomy. "Results showed that MRI correctly identified 87/92 (95%) of ...
... colonography allows radiologists to predict, with a high degree ... be evaluated through colonoscopy or removed through polypectomy, according ... School of Medicine and Public Health in Madison, WI. ... CT colonography (CTC) detected lesions. "In our study, we ...
... 25 is World Malaria Day. , ... (Vocus) April 23, 2009 -- ... Nations Foundation and its Nothing But Nets campaign to create a platform ... and the UN Foundation will provide opportunities for underprivileged youth to take ...
... | About 400 cancer therapy specialists from 100 countries (96 ... in Vienna at an IAEA event to discuss modern techniques ... on Advances in Radiation Oncology (ICARO) will start on Monday, ... Vienna International Center. , All sessions of the event ...
... Medical Technologies, Inc. (Nasdaq: PMTI ), a leading ... hold its quarterly conference call of its 2009 first quarter ... Eastern Time. If you would like to participate, please call ... The telephone replay will be available one hour after the ...
... Addicts, even those who have been abstinent for long periods ... of prior drug use. For example, exposure to the ... contextual memory can increase their craving for the drug ... in the April 15th issue of Biological Psychiatry ...
Cached Medicine News:Health News:IAEA conference to focus on new techniques in cancer treatment 2Health News:Palomar Medical Technologies to Host First Quarter 2009 Financial Results Conference Call and Webcast on April 30, 2009 2Health News:Treating addiction by eliminating drug-associated memories 2
(Date:7/29/2014)... , July 29, 2014 New high ... Medicare Part D by a projected $2.9 to $5.8 ... the actuarial firm Milliman released today by the Pharmaceutical ... D premiums could increase by as much as 8.6 ... C drugs, including Sovaldi and Olysio. The ...
(Date:7/29/2014)... ISPE—the International Society for Pharmaceutical Engineering ... as President and CEO, succeeding Nancy ... Society last fall.  Mr. Bournas takes the helm ... association industry as well as significant international experience.  ... for the expansion of its global initiatives and ...
(Date:7/29/2014)... LAUDERDALE, Fla. , July 29, 2014 /PRNewswire-iReach/ ... medical service provider, has launched its Medical ... Program.  These services are tailored to the ... excellent standards prompted industry operators to propose that ... MHG Medical,s new program is intended to ...
Breaking Medicine Technology:New Milliman Study: Hepatitis C Drugs Could Increase Medicare Part D Spending by $2.9 to $5.8 Billion in 2015 2ISPE Hires Healthcare Association Exec as CEO 2ISPE Hires Healthcare Association Exec as CEO 3MHG Medical Management Services Aims to Change Cruise Industry Standard With New Equipment Maintenance Program 2
... 7, 2011 BioSpecifics Technologies Corp. (Nasdaq: ... developing first in class collagenase-based products, today announced that ... (the "Rights Agreement"), adopted May 14, 2002 and previously ... Amendment increases the ownership threshold for determining "Acquiring Person" ...
... FRANCISCO, Feb. 7, 2011 Medivation, Inc. (Nasdaq: ... chief executive officer, will present at the 13th Annual BIO ... a.m. Eastern Time at the Waldorf-Astoria in New York. ... its clinical development programs for MDV3100 for prostate cancer and ...
Cached Medicine Technology:
Shandon Paraffin Block Cartons...
... A histological embedment block ... This file system incorporates ... embedment block protection, simplified ... error and facilitation of ...
The Modular Storage Drawers provide permanent storage and identification of up to 165 embedding rings or 250 cassettes per drawer....
... The first instrumentation ... efficiently manage the ... Proven technology automatically ... collates cassettes sequentially. ...
Medicine Products: