Navigation Links
JCI online early table of contents: May 17, 2010
Date:5/10/2010

cles/view/40141?key=dc42b930fbb1a36725f5">http://www.jci.org/articles/view/40141?key=dc42b930fbb1a36725f5


GASTROENTEROLOGY: Reducing colon cancer risk in a model of inflammatory bowel disease

Individuals with inflammatory bowel disease (IBD) have an increased risk of developing colon cancer because of the chronic inflammation in their guts. A potential new therapeutic approach to reducing this risk has now been suggested by Deborah Rubin and colleagues, at Washington University School of Medicine, Saint Louis, as a result of their work in a mouse model of IBD-induced colon cancer.

In the study, they find that mice lacking the protein epimorphin are protected from inflammation-induced colon cancer, likely as a result of increased repair of the lining of the gut and decreased levels of the proinflammatory factor IL-6. They therefore suggest that modulating epimorphin levels may have therapeutic benefits and help protect individuals with IDB from going on to develop colon cancer.

TITLE: Epimorphin deletion protects mice from inflammation-induced colon carcinogenesis and alters stem cell niche myofibroblast secretion

AUTHOR CONTACT:
Deborah C. Rubin
Washington University School of Medicine, Saint Louis, Missouri, USA.
Phone: 314.362.8935; Fax: 314.362.8959; E-mail: drubin@wustl.edu.

View this article at: http://www.jci.org/articles/view/40676?key=a68a794497995c07a248


ONCOLOGY: COMManDing a role in tumor invasion

Little is known about the function of the COMMD family of proteins. However, a team of researchers, at the University of Texas Southwestern Medical Center, Dallas, and University Medical Centre Maastricht, The Netherlands, has now found that COMMD1, the prototypic member of the COMMD family, has a role in tumor inva
'/>"/>

Contact: Karen Honey
press_releases@the-jci.org
734-546-5242
Journal of Clinical Investigation
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8

Related medicine news :

1. A medicine classic goes online and far afield
2. New Online Service Helps Patients Find Info on Pricing, Financial Assistance
3. Horizon Display Demonstrates their Dedication to After-Sales Support with Enhanced Online Resources
4. CareData Introduces Online Electronic Health Record Training Course for Allied Health Paraprofessionals
5. LeveragePoint Releases Complete Online Value Management Solution
6. SeaShine, LLC Announces the Launch of SeaShine Online Magazine, a Magazine for Women Who Positively Impact their Communities through Transparent Lifestyles
7. Leveragepoint Names Jay Manson Vice President Sales For Online Value Management Tools
8. Prize4Life Launches “Art, Life, Spring” Online Art Auction to Raise Funds for Lou Gehrig's Disease Research
9. ShenoaDiamonds.com Holds Contest to Give Away $5,000 Diamond Ring, Spurred by Online Sales Growth
10. New Online Stores & Online Shopping Collection Web Site
11. The Diet Solution Program: Popular Online Weight Loss Program is Revised to Include More Metabolism Boosting Meals
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/25/2014)... TX (PRWEB) December 26, 2014 This ... state of the global Sterilizers industry with a focus ... on the market status of the Sterilizers manufacturers and ... companies and individuals interested in the industry. This report ... definition, applications and manufacturing technology. In this part, the ...
(Date:12/25/2014)... (PRWEB) December 25, 2014 Product liability ... ASR hip recall ( http://www.consumerinjurylawyers.com/DePuy/ ) continue to move ... to an Order issued in the U.S. District Court, ... will convene an open conference on January 7, 2015, ... States Courthouse in West Palm Beach, Florida. The Conference ...
(Date:12/25/2014)... 25, 2014 The short film “Color of ... in honor of a true 9/11 hero, Welles Remy Crowther. ... including the 24 hours of Nuremberg International Short Film Festival ... , Actress, screenwriter and director Luciana Lagana plays ... together with her husband, Gregory Graham - Graham ...
(Date:12/25/2014)... When head lice hits a home or school, ... get rid of it while keeping it from taking over ... have the solution right in their neighborhood: Lice Troopers ... provides full spectrum head lice screening and treatment services to ... Key Biscayne, Brickell, Coconut Grove, Kendall, Pinecrest and South Miami. ...
(Date:12/25/2014)... -- Overeating is common during the holidays, but there are ... says. "Don,t arrive at a party hungry. It may ... be attending a party, but deprivation leads to hunger, and ... Westchester Hospital in Mount Kisco, N.Y., said in a hospital ... day and even to have a snack before attending a ...
Breaking Medicine News(10 mins):Health News:Sterilizers Industry Global and Chinese Analysis for 2009-2019 Now Available at ReportsnReports.com 2Health News:Sterilizers Industry Global and Chinese Analysis for 2009-2019 Now Available at ReportsnReports.com 3Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 3Health News:The True 9/11 Hero Story “Color of Honor” Premieres in Germany and Bangladesh: Luciana Lagana Plays the Mother of the Lead and Co-Produces with Blaise Dolcemaschio. 2Health News:The True 9/11 Hero Story “Color of Honor” Premieres in Germany and Bangladesh: Luciana Lagana Plays the Mother of the Lead and Co-Produces with Blaise Dolcemaschio. 3Health News:Coral Gables Florida Gets Ready to Be Lice-Free with Lice Troopers 2
... ... MRSA, VENICE, Fla., ... today from a,successful in vivo pilot study indicating that its patented SinoFresh(R),nasal ... nasal passages. This study utilized a recognized scientific model,intended to demonstrate SinoFresh(R) ...
... Canes to be Provided Nationwide, BALTIMORE, Aug. 19 ... largest organization of blind,people, today announced an initiative to ensure ... who needs a long white cane will have,one, regardless of ... to,anyone in the fifty states, the District of Columbia, or ...
... & COO, Former Experian Executive Will Lead Private Access, Mission ... web-based privacy management and ... clinical trials recruitment tools, ALISO VIEJO, Calif., ... that enable management of detailed,privacy preferences for personal health information, ...
... MD, August 19, 2008 The prevalence of obesity ... increased risk of gastrointestinal diseases related to obesity raises ... studies in the August issue of The American ... and the risk of colorectal cancer and gastroesophageal reflux ...
... digital pathology solutions for cancer diagnosis and preclinical research, today announced ... by Burrill & Company. Ascension Health Ventures, National Healthcare Services and ... with strong support. , ... CUPERTINO, Calif. (Business ...
... open NHPCO,s 9th Clinical Team Conference on October ... Edwards,is deeply committed to improving America,s future. A ... has been a vocal advocate and,tireless worker on ... healthcare in America. Mrs. Edwards will be the ...
Cached Medicine News:Health News:SinoFresh(R) Nasal Spray Kills MRSA 'Super-Bug' in Live Noses 2Health News:SinoFresh(R) Nasal Spray Kills MRSA 'Super-Bug' in Live Noses 3Health News:National Federation of the Blind Launches Largest-Ever White Cane Initiative 2Health News:VirtualHealth Technologies, Inc., Announces Its Associate, Private Access, Appoints Marc Kirshbaum as President & COO 2Health News:VirtualHealth Technologies, Inc., Announces Its Associate, Private Access, Appoints Marc Kirshbaum as President & COO 3Health News:Obesity raises risks of serious digestive health concerns 2Health News: BioImagene Raises $26 M in Expansion Capital 2Health News:Elizabeth Edwards to be Opening Speaker at National Hospice Conference in Dallas 2
(Date:12/24/2014)... -- Commonwealth Cornerstone Group (CCG) today announced the completion of an ... help fund the expansion and consolidation of healthcare services provided ... . PHN is the largest federally qualified ... is the largest employer in Sharon,s ... Currently, PHN Sharon offers scattered services out of ...
(Date:12/24/2014)... N.Y. , Dec. 24, 2014 Kinex ... dosed with KX2-361 at Roswell Park Cancer Institute. ... small molecule drug that has shown potent inhibitory activity ... including those that are resistant to Temozolomide (T98G), the ... glioma. In a well-established brain tumor mouse model, KX2-361 ...
(Date:12/24/2014)... International Trade Commission (ITC) issued its final decision in the ... notice issued on December 23, the ITC ruled in favor ... was invalid. BMC President, James Xu ... with the ITC,s decision in this case. This victory for ... very beginning on the key patents in the case. ResMed ...
Breaking Medicine Technology:Commonwealth Cornerstone Group Announces $8 Million in Tax Credits to Expand and Consolidate Healthcare Services in Sharon 2Commonwealth Cornerstone Group Announces $8 Million in Tax Credits to Expand and Consolidate Healthcare Services in Sharon 3Kinex Pharmaceuticals Announces First Patient Dosed with KX2-361 in a Phase 1 Clinical Study 2Kinex Pharmaceuticals Announces First Patient Dosed with KX2-361 in a Phase 1 Clinical Study 3ITC Final Decision Goes Against ResMed (RMD) Monumental Win for 3B/BMC 2
... N.J., Oct. 26, 2011 Pharmaceutical gurus know that the ... is to get together with the field,s leading experts. And ... popular event that takes place just once a year: the ... 7-8 at the Hilton Parsippany Hotel in Parsippany, New Jersey. ...
... the leading innovator in epicardial ablation devices, announced today ... and www.ncontactinc.com . The design of the ... and the market for treating cardiac arrhythmias that affect ... are excellent educational references that highlight how our technology ...
Cached Medicine Technology:Pharmaceutical Industry Leaders to Tackle Groundbreaking Challenges, Opportunities for Pharma & Biotech at Elite Event 2nContact, Inc. Launches New Corporate Websites 2
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: