Navigation Links
JCI online early table of contents: May 1, 2009
Date:5/1/2009

EF="mailto:metelits@bcm.tmc.edu">metelits@bcm.tmc.edu.

View the PDF of this article at: https://www.the-jci.org/article.php?id=37869


METABOLISM: The sweet smell of success: new understanding of the pathway affected in Maple Syrup Urine Disease

Yibin Wang and colleagues, at UCLA David Geffen School of Medicine, Los Angeles, have identified, in cultured cells and mice, a protein responsible for regulating the protein complex that breaks down branched-chain amino acids (three protein building blocks that cannot be made by humans but have to be obtained from the food we eat). Mice lacking this protein (PP2Cm) exhibited similar symptoms to some forms of human Maple Syrup Urine Disease (MSUD), an inherited disorder characterized by sweet-smelling urine that leads to severe brain damage and death if untreated. The authors therefore suggest that defects in PP2Cm may be responsible for some cases of MSUD.

TITLE: Protein phosphatase 2Cm is a critical regulator of branched chain-amino acid catabolism in mice and cultured cells

AUTHOR CONTACT:
Yibin Wang
David Geffen School of Medicine, University of California, at Los Angeles, Los Angeles, California, USA.
Phone: (310) 206-5197; Fax: (310) 206-5907; E-mail: yibinwang@mednet.ucla.edu.

View the PDF of this article at: https://www.the-jci.org/article.php?id=38151


CARDIOLOGY: The fog lifts on the role for the protein Fog2 in the adult heart

The protein Fog2, which is a regulator of gene expression, is essential for embryonic development of both the heart and the blood vessels that supply the heart (coronary blood vessels), but its role in the adult heart has not been determined. However, William Pu and colleagues, at Children's Hospital Boston,
'/>"/>

Contact: Karen Honey
press_releases@the-jci.org
215-573-1850
Journal of Clinical Investigation
Source:Eurekalert

Page: 1 2 3 4 5

Related medicine news :

1. ScienceRoll.com On How to Follow Swine Flu Information Online
2. Medifecta Healthcare Training Launches Website with Educational Resources and Online Training for Caregivers
3. Medeguide Announces Online Marketing Partnership with Admax Plus to Promote Doctors and Treatment Packages Online
4. RightSignature Announces Beta Launch of Breakthrough Online Document Signing Service
5. Penn Foster Career School Launches Online Certified Personal Trainer Program
6. Copper Conferencing Announces Dr. Joy Ohayia Kicks Off the Women In Business Track of The Business Webinar Series - A Free Online Learning Series for Business Professionals
7. PeopleStreme Releases RapidEcho Online Tool for Employee Personal Development
8. Tennenbaum Encourages Shareholders to Vote the Blue Proxy for Tennenbaum Director Nominees at Online Resources Annual Meeting as Recommended by Riskmetrics/ISS and Proxy Governance
9. Thomson Reuters and the National Foundation for Cancer Research Provide Online Help for Cancer Patients
10. Video: Adults Facing ADHD: ADHD Allies(TM) Offers Unique Online Community for Adults with ADHD on New Facebook(R) Page
11. IOUSOS™ Launches Online Consumer Medical Bill Clearinghouse: New Service Set to Help More than 50 Million Americans and Healthcare Providers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/25/2015)... NY (PRWEB) May 26, 2015 ... Anne King as a 2015-2016 inductee into ... is recognized with this prestigious distinction for leadership in ... exclusively for professional women, boasting more than 700,000 members ... pleased to welcome Anne into this exceptional group of ...
(Date:5/25/2015)... City, NY (PRWEB) May 26, 2015 ... honors Laquanis Hooker as a 2015-2016 inductee into its ... recognized with this prestigious distinction for leadership in dentistry. ... professional women, boasting more than 700,000 members and over ... welcome Laquanis into this exceptional group of professional women,” ...
(Date:5/25/2015)... (PRWEB) May 26, 2015 ... honors Dr. Heather Stanley-Christian as a ... Year Circle. She is recognized with this prestigious ... nation's leading networking organization exclusively for professional women, ... operating local chapters. , "I'm pleased to welcome ...
(Date:5/25/2015)... The National Association of Professional ... as a 2015-2016 inductee into its VIP Woman of ... distinction for leadership in biomedical engineering. NAPW is the ... more than 700,000 members and over 200 operating Local ... exceptional group of professional women," said NAPW President Star ...
(Date:5/25/2015)... 25, 2015 World Patent Marketing, a ... The Preventer, a home patent that aims to protect ... , "House fires cost the United States a total ... and Creative Director of World Patent Marketing . ... homes that have no alarmed protection. With the use ...
Breaking Medicine News(10 mins):Health News:National Association of Professional Women Inducts Anne King, Operating Principal at Keller Williams, Into its VIP Professional Woman of the Year Circle 2Health News:National Association of Professional Women Inducts Dr. Laquinas Hooked, D.D.S. of General Dentist, Into its VIP Professional Woman of the Year Circle 2Health News:NAPW Inducts Dr. Heather Stanley-Christian, Systems Chair/Maternal Fetal Medicine at Stroger Hospital, into Its VIP Professional Woman of the Year Circle 2Health News:National Association of Professional Women Inducts Lisa Ferrara, Ph.D., CEO of OrthoKinetic Technologies, Into its VIP Professional Woman of the Year Circle 2Health News:Home Maintenance Causes House Fires? World Patent Marketing Introduces the Best Home Patent to Prevent Fire Accidents 2Health News:Home Maintenance Causes House Fires? World Patent Marketing Introduces the Best Home Patent to Prevent Fire Accidents 3
... Specialty Pharmaceutical Company with Greater Commercialization Capabilities, Expanded Portfolio of Pain ... King Extends Tender Offer Through December 19, 2008 ... N.J., Nov. 24 King Pharmaceuticals, Inc. (NYSE: KG ... that the two companies have signed a definitive merger agreement under ...
... Nov. 24 Transdel,Pharmaceuticals, Inc. (OTC Bulletin Board: ... and commercialization of non-invasive,topically targeted medications, today announced ... Company,s Board of Directors. , ... Swann, Inc., a consulting firm specializing in,marketing and ...
... resorts,are opening for the season, the Kelly Brush Foundation kicked ... the announcement of,over $20,000 in grants to ski racing clubs ... campaign to promote and improve ski racing safety. , ... of the most prestigious racing programs in,the nation including the ...
... DaVita Inc., a,leading provider of kidney care services ... kidney failure, continues to enhance DaVita.com to,make it ... well as a valuable,resource for patient education. DaVita.com/physicians ... people with chronic kidney disease and can,be found ...
... 24 ATS Medical, Inc.,(Nasdaq: ATSI ... and services, today announced that the first three ... completed by Dr. Allan,Stewart, Director, Aortic Surgery Program ... York ( http://www.ctsnet.org/home/allanstewart ) on November 17,and 18, ...
... ,Tis may be the season to be jolly but,tis ... lines that,barely move and public places stuffed with wheezing, sneezing ... makes keeping fit and healthy a bit of a challenge. ... find,Life123.com a comforting, mouse-click away. If you feel a ...
Cached Medicine News:Health News:King Pharmaceuticals To Acquire Alpharma for Approximately $1.6 Billion 2Health News:King Pharmaceuticals To Acquire Alpharma for Approximately $1.6 Billion 3Health News:King Pharmaceuticals To Acquire Alpharma for Approximately $1.6 Billion 4Health News:King Pharmaceuticals To Acquire Alpharma for Approximately $1.6 Billion 5Health News:King Pharmaceuticals To Acquire Alpharma for Approximately $1.6 Billion 6Health News:King Pharmaceuticals To Acquire Alpharma for Approximately $1.6 Billion 7Health News:King Pharmaceuticals To Acquire Alpharma for Approximately $1.6 Billion 8Health News:King Pharmaceuticals To Acquire Alpharma for Approximately $1.6 Billion 9Health News:Transdel Pharmaceuticals Appoints Mr. Lynn Swann, Pro-Football Hall of Famer, ABC Sports Broadcaster, and Former Chairman of the President's Council on Physical Fitness and Sports, to Board of Directors 2Health News:Transdel Pharmaceuticals Appoints Mr. Lynn Swann, Pro-Football Hall of Famer, ABC Sports Broadcaster, and Former Chairman of the President's Council on Physical Fitness and Sports, to Board of Directors 3Health News:Kelly Brush Foundation Awards Ski Racing Safety Grants 2Health News:DaVita.com Launches Physician Website 2Health News:DaVita.com Launches Physician Website 3Health News:ATS Medical Announces First Commercial Implants of the ATS 3f Aortic Bioprosthesis in the United States 2Health News:ATS Medical Announces First Commercial Implants of the ATS 3f Aortic Bioprosthesis in the United States 3Health News:Staying Healthy This Holiday Season Can be as Easy as Life123 2
(Date:5/22/2015)... HILL, N.C. , May 22, 2015 /PRNewswire/ ... be hosting its sixth Medical Affairs ... 12:30PM (EDT) via a virtual roundtable to discuss ... Research." Best Practices, Medical Affairs Consortium ... sharing insights about the key challenges they face. ...
(Date:5/22/2015)... Taskforce representing Canada,s living victims of ... the Minister and Health Canada have put into this program ... of the thalidomide survivors, and more than 70% of them ... annual adjustments for inflation. Certain of the thalidomide ... on the severity of their disability, tax free, with inflation ...
(Date:5/22/2015)... 22, 2015  Amgen (NASDAQ: AMGN ... termination of its participation in the co-development ... STO:AZN and NYSE: AZN ).  Brodalumab, ... for patients with moderate-to-severe plaque psoriasis, psoriatic ... based on events of suicidal ideation and ...
Breaking Medicine Technology:Best Practices Sixth Medical Affairs Consortium Roundtable to Focus on Health Economics & Outcomes Research 2Amgen to terminate participation in co-development and commercialization of brodalumab 2Amgen to terminate participation in co-development and commercialization of brodalumab 3Amgen to terminate participation in co-development and commercialization of brodalumab 4Amgen to terminate participation in co-development and commercialization of brodalumab 5
... MISSISSAUGA, Ontario, March 29, 2011 GlaxoSmithKline (GSK) and ... (TSX: VRX) announced today that the European Commission has ... (add-on) treatment of partial onset seizures (a form of ... in one side of the brain), with or without ...
... Metabolic Solutions Development Company (MSDC), a drug discovery ... treat metabolic diseases, announced today that it has ... company,s second drug candidate for the treatment of ... and placebo-controlled clinical trial will involve approximately 125 ...
Cached Medicine Technology:GSK and Valeant Receive European Authorisation for Trobalt (retigabine) 2GSK and Valeant Receive European Authorisation for Trobalt (retigabine) 3GSK and Valeant Receive European Authorisation for Trobalt (retigabine) 4GSK and Valeant Receive European Authorisation for Trobalt (retigabine) 5Metabolic Solutions Development Company Launches Phase 2a Trial of Its Second Compound to Treat Type 2 Diabetes 2
Designed to determine the precise length of limbal incisions and proper alignment of closing sutures. Curved marking blade with 2 mm lines spaced 1 mm apart-measures up to 10 mm. Round knurled handle...
Endoscopes are also available in fully autoclavable models in 1.8, 2.7, 4.0. 5.0 and 10.0 mm diameters. Manufactured with precise swiss lenses. Built-in temperature measuring device to exactly determ...
Endoscopes are also available in fully autoclavable models in 1.8, 2.7, 4.0. 5.0 and 10.0 mm diameters. Manufactured with precise swiss lenses. Built-in temperature measuring device to exactly determ...
Endoscopes are also available in fully autoclavable models in 1.8, 2.7, 4.0. 5.0 and 10.0 mm diameters. Manufactured with precise swiss lenses. Built-in temperature measuring device to exactly determ...
Medicine Products: