Navigation Links
JCI online early table of contents: July 12, 2010
Date:7/12/2010

g/articles/view/42642?key=8810b92e3074e99478bd">http://www.jci.org/articles/view/42642?key=8810b92e3074e99478bd


EDITOR'S PICK: TIMely intervention for asthma

Asthma can be a severely debilitating disease. Its increasing prevalence and the fact that most treatments do not control severe asthma well has stimulated intensive research into genetic susceptibility to asthma in the hope that the information gleaned will lead to new therapeutics. One gene identified as a asthma susceptibility gene is TIM1 and now, a team of researchers, led by Paul Rennert, at Biogen Idec Inc., Cambridge, has generated data in a humanized mouse model of asthma that suggest that targeting TIM-1 protein might have therapeutic benefit in the treatment of patients with asthma. Specifically, the team found that an antibody that bound to a defined region of the TIM-1 protein (a cleft formed within the IgV domain) had therapeutic activity in the humanized mouse model of experimental asthma, ameliorating inflammation and airway hyperresponsiveness.

TITLE: Antagonism of TIM-1 blocks the development of disease in a humanized mouse model of allergic asthma

AUTHOR CONTACT:
Paul D. Rennert
Biogen Idec Inc., Cambridge, Massachusetts, USA.
Phone: 617.679.2986; Fax: 617.679.2304; E-mail: paul.rennert@biogenidec.com.

View this article at: http://www.jci.org/articles/view/39543?key=847e756d2bc7b2f37250


EDITOR'S PICK: The hormone IGF-1: a trigger of puberty

The onset of puberty is triggered by pulsatile release of the hormone GnRH from nerve cells in a region of the brain known as the hypothalamus. Exactly what signals tell these nerve cells to release GnRH in this manner has not been determined, although it has been suggested that hormones associated with good
'/>"/>

Contact: Karen Honey
press_releases@the-jci.org
734-546-5242
Journal of Clinical Investigation
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8

Related medicine news :

1. Online coverage of XVIII International AIDS Conference to include daily webcasts, live coverage, podcasts and news recaps
2. Sam's Club Tests Online Small Business Loan Program for Main Street
3. SNM cautions that Canadas Chalk River coming back online will not solve long-term isotope shortage
4. Suite 101.com Provides Insight Into Consumer Reading Behavior Online
5. Grand Opening of GreenProductsandGifts.com Online Store Offering Eco Friendly Gifts that are Proudly Made in the USA
6. Vibration Exercise Equipment Available at Fitness4HomeOnline.com
7. Onlineshoes.com and New Balance Pair Up for Toning Shoes Giveaway
8. Online Deals on Golf, now in Full Swing at GolfAdventures.com
9. BVibrantNow, A New All-Natural Health Supplement Business, Launches Free Online Wellness Calendar to Promote Healthy Habits
10. Publishing and Media Distribution Firm Launches Online Public Relations Kit for Businesses Seeking Free Publicity
11. JCI online early table of contents: July 1, 2010
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... (PRWEB) July 28, 2014 ... "McDonald’s continues to market to a disadvantaged ... Hispanic. They use proven, often offensive, ethnically-slanted ... of people." ('The Tainted Burger." Amazon: ... with Anna Lappe', author and activist who ...
(Date:7/27/2014)... (PRWEB) July 28, 2014 Zensah®, the leader ... offering to include a wrist support . The wrist ... the wrist area. , Lateral and Medial Epicondylitis, more commonly ... condition in which there is inflammation of the tendons attached ... unrelated to wrist pain, the muscles that work the wrist ...
(Date:7/27/2014)... a reliable online supplier of women’s special occasion outfits, has ... on its website. Now, all these charming gowns are provided ... are pleased to add the new fabulous prom dress collection ... who are in need of fashionable special occasion outfits. Each ... our clients will love them. Ladies, just visit our online ...
(Date:7/27/2014)... Bags underneath the eyes is one condition that both ... a range of new products now available from Internet retailers. ... serum review that is now posted for adults to access ... with baggy eyes and how the natural ingredients in some ... also provides a detailed overview of the creams and oils ...
(Date:7/27/2014)... virus (HEV) transmission by blood components indicates that about ... their plasma. The findings, published in The Lancet ... red cells, platelets, and fresh frozen plasma) are likely ... The study retrospectively screened 225 000 individual blood donations ... Sept, 2013 for HEV RNA. 79 donors were found ...
Breaking Medicine News(10 mins):Health News:The Tainted Burger- McDonalds's Franchise Owner's Tale by Author Michael B. Potts Says McDonald's Disproportionately Markets to Minorities--Tedx Video Supports Claim 2Health News:Zensah® Releases New Wrist Support 2Health News:Wdsshop.de Unveils New Prom Dresses To Expand The Online Market 2Health News:Baggy Eyes Serum Review Posted for Men and Women at Cherry News Website 2Health News:The Lancet: 1 in 3000 blood donors in England infected with hepatitis E 2
... Feb. 3 The Ensign Group, Inc. (Nasdaq: ... into Colorado by acquiring four long-term care facilities in ... a 35-bed skilled nursing facility in Littleton, Arvada Nursing ... Temple Center, a 128-bed skilled nursing facility in Englewood, ...
... DEL MAR, Calif., Feb. 3 Plastic & ... the field, published the remarkable safety record of ... killer blood clots to the lungs (pulmonary embolism ... over the past 16 years! This series included ...
... for online vacuum cleaner reviews. , ... Boise, Idaho (PRWEB) February 3, ... will collaborate with The Carpet and Rug Institute (CRI) to ... "Seal of Approval" designation. , , , , ,The new series seeks ...
... web based user self service & identity management software solution that allows ... accounts easily and securely via a web browser, and ends the need ... ... 3, 2009 -- SysOp Tools, Inc. announced that Password Reset PRO, a ...
... Feb. 3 Beneficiaries enrolled in Medicare Part D ... as the "doughnut hole" were much less likely to ... according to a University of Pittsburgh Graduate School of ... 3 online issue of Health Affairs , raise ...
... in the February issue of the Journal of the ... to 20 minutes with simple surgical exercises prior to an ... skills in surgeons of all experience levels. The researchers found ... surgeons, alertness to a higher level for surgical procedures and ...
Cached Medicine News:Health News:The Ensign Group Expands into Colorado 2Health News:Cosmetic Surgery - No Killer Blood Clots to the Lungs Sans GA, PK Anesthesia Can Save the Day 2Health News:The Housekeeping Channel (HC) and The Carpet and Rug Institute (CRI) Partner on Vacuum Cleaner Reviews 2Health News:The Housekeeping Channel (HC) and The Carpet and Rug Institute (CRI) Partner on Vacuum Cleaner Reviews 3Health News:New Web-Based User Self Service & Identity Management Software for Active Directory takes Security, User Convenience to a Whole New Level 2Health News:New Web-Based User Self Service & Identity Management Software for Active Directory takes Security, User Convenience to a Whole New Level 3Health News:Seniors in Medicare's doughnut hole decrease use of meds 2Health News:Journal of American College of Surgeons study finds warm-up helps surgeons improve performance 2
(Date:7/25/2014)... , July 25, 2014  Arena Pharmaceuticals, Inc. ... provide a corporate update and report second quarter 2014 ... on Friday, August 1, 2014. That same day, Arena ... a.m. Eastern Time (5:30 a.m. Pacific Time). ... 877.643.7155 for domestic callers and 914.495.8552 for international callers. ...
(Date:7/24/2014)... Kan. , July 24, 2014  Parnell ... two compounds that will be added to Parnell,s ... Australian-based CIMTECH Pty Ltd, a biotechnology company. The ... 122 have shown promise in bone regeneration and ... to develop the compounds for the veterinary market ...
(Date:7/24/2014)... , Deutschland, und MARSEILLE ... -- , Weltweite ... ermöglicht QIAGEN die Entwicklung von Tests ... für Blutkrebs  Neuer Test weist ... mit Knochenmarkserkrankungen (myelodysplastischen Syndromen) einen günstigen Krankheitsverlauf ...
Breaking Medicine Technology:Arena Pharmaceuticals to Host Corporate Update and Financial Results Conference Call and Webcast on Friday, August 1 2Arena Pharmaceuticals to Host Corporate Update and Financial Results Conference Call and Webcast on Friday, August 1 3Parnell Acquires License for Intellectual Property and Rights to Develop Compounds for Bone and Dermal Regeneration 2Parnell Acquires License for Intellectual Property and Rights to Develop Compounds for Bone and Dermal Regeneration 3Parnell Acquires License for Intellectual Property and Rights to Develop Compounds for Bone and Dermal Regeneration 4QIAGEN erweitert Pipeline für die personalisierte Medizin um vielversprechende genomische Biomarker zur Prognosebestimmung bei Blutkrebsbehandlungen 2QIAGEN erweitert Pipeline für die personalisierte Medizin um vielversprechende genomische Biomarker zur Prognosebestimmung bei Blutkrebsbehandlungen 3QIAGEN erweitert Pipeline für die personalisierte Medizin um vielversprechende genomische Biomarker zur Prognosebestimmung bei Blutkrebsbehandlungen 4QIAGEN erweitert Pipeline für die personalisierte Medizin um vielversprechende genomische Biomarker zur Prognosebestimmung bei Blutkrebsbehandlungen 5
... Reportlinker.com announces that a new market research ... Levosimendan - Comprehensive patent search ... unnecessary risk with the industry benchmark in comprehensive ... regularly updated, professional patent search performed by our ...
... 20, 2011 Sagent Pharmaceuticals (Nasdaq: SGNT ) ...  The size of the offering has been increased from the ... of common stock at a price to the public of ... on The NASDAQ Global Market on April 20, 2011 under ...
Cached Medicine Technology:Reportlinker Adds Levosimendan - Comprehensive patent search 2Reportlinker Adds Levosimendan - Comprehensive patent search 3Reportlinker Adds Levosimendan - Comprehensive patent search 4Sagent Pharmaceuticals Upsizes and Prices Initial Public Offering 2
... the most advanced visual electrodiagnostic system ... of retinal and optic nerve function. ... drives this powerful computer-controlled instrument. With ... pattern stimulation, rapid Ganzfeld flash rate ...
... The Universal Biomedical Amplifier (UBA-4204) ... true DC signal amplification and ... commonly seen amplifier problems of ... saturation. These features make the ...
The STALIF stand-alone anterior lumbar fusion cage is the latest product development from Surgicraft. STALIF is the natural evolution of the Hartshill Horseshoe, which has over 10 years clinical suc...
... PACHETTE 3 will enable eye care professionals ... utilizing improved ultrasound technology. The PACHETT 3 ... algorithm used in all the DGH pachymeters ... DGH Model 555 PACHETTE 3 is capable ...
Medicine Products: