Navigation Links
JCI online early table of contents: July 12, 2010
Date:7/12/2010

g/articles/view/42642?key=8810b92e3074e99478bd">http://www.jci.org/articles/view/42642?key=8810b92e3074e99478bd

EDITOR'S PICK: TIMely intervention for asthma

Asthma can be a severely debilitating disease. Its increasing prevalence and the fact that most treatments do not control severe asthma well has stimulated intensive research into genetic susceptibility to asthma in the hope that the information gleaned will lead to new therapeutics. One gene identified as a asthma susceptibility gene is TIM1 and now, a team of researchers, led by Paul Rennert, at Biogen Idec Inc., Cambridge, has generated data in a humanized mouse model of asthma that suggest that targeting TIM-1 protein might have therapeutic benefit in the treatment of patients with asthma. Specifically, the team found that an antibody that bound to a defined region of the TIM-1 protein (a cleft formed within the IgV domain) had therapeutic activity in the humanized mouse model of experimental asthma, ameliorating inflammation and airway hyperresponsiveness.

TITLE: Antagonism of TIM-1 blocks the development of disease in a humanized mouse model of allergic asthma

AUTHOR CONTACT:
Paul D. Rennert
Biogen Idec Inc., Cambridge, Massachusetts, USA.
Phone: 617.679.2986; Fax: 617.679.2304; E-mail: paul.rennert@biogenidec.com.

View this article at: http://www.jci.org/articles/view/39543?key=847e756d2bc7b2f37250

EDITOR'S PICK: The hormone IGF-1: a trigger of puberty

The onset of puberty is triggered by pulsatile release of the hormone GnRH from nerve cells in a region of the brain known as the hypothalamus. Exactly what signals tell these nerve cells to release GnRH in this manner has not been determined, although it has been suggested that hormones associated with good
'/>"/>

Contact: Karen Honey
press_releases@the-jci.org
734-546-5242
Journal of Clinical Investigation
Source:Eurekalert

0

GOOD

Page: 1 2 3 4 5 6 7 8

Related medicine news :

1. Online coverage of XVIII International AIDS Conference to include daily webcasts, live coverage, podcasts and news recaps
2. Sam's Club Tests Online Small Business Loan Program for Main Street
3. SNM cautions that Canadas Chalk River coming back online will not solve long-term isotope shortage
4. Suite 101.com Provides Insight Into Consumer Reading Behavior Online
5. Grand Opening of GreenProductsandGifts.com Online Store Offering Eco Friendly Gifts that are Proudly Made in the USA
6. Vibration Exercise Equipment Available at Fitness4HomeOnline.com
7. Onlineshoes.com and New Balance Pair Up for Toning Shoes Giveaway
8. Online Deals on Golf, now in Full Swing at GolfAdventures.com
9. BVibrantNow, A New All-Natural Health Supplement Business, Launches Free Online Wellness Calendar to Promote Healthy Habits
10. Publishing and Media Distribution Firm Launches Online Public Relations Kit for Businesses Seeking Free Publicity
11. JCI online early table of contents: July 1, 2010
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/21/2013)... (PRWEB) May 21, 2013 Go Classy ... today that they have redesigned their website featuring ... beach, pool, hot tubs, bars and dining. The website, ... resort including sales and guest reviews, will now have ... Jamaica itself, including pages on culinary local recipes, flora ...
(Date:5/21/2013)... May 21, 2013 The American Diabetes ... people in the United States of America are affected ... at a great risk of developing peripheral neuropathy which ... lives. The ADA further goes on saying that the ... and around 2 million new cases are diagnosed every ...
(Date:5/21/2013)... (HealthDay News) -- Aggressive treatment for prostate cancer ... with underlying medical conditions, a new study finds. ... radiation and radioactive seed implants, can cause serious ... and bowel problems, explained researchers from the University ... found that older patients with slower growing forms ...
(Date:5/21/2013)... for research and economic development will urge congressional ... of supercomputers designed to tackle complex societal questions, ... Daniel Reed will appear at a hearing on ... Energy, titled, "America,s Next Generation Supercomputer: The Exascale ... Room 2318 of the Rayburn House Office Building ...
(Date:5/21/2013)... 21 (HealthDay News) -- When a classmate commits suicide, ... themselves, according to a new study. This "suicide contagion" ... student personally, the researchers found. Teens aged 12 ... by Dr. Ian Colman, Canada Research Chair in Mental ... of Public Health. The study appeared May 21 in ...
Breaking Medicine News(10 mins):Health News:The Oldest and Original Nudist Travel Agency for NResort Announced Today a Redesigned Website Featuring Information on Culinary Events, Flora and Fauna, and Photography 2Health News:Neuracel Aims to Reduce Peripheral Neuropathy Pain 2Health News:Age, Other Illnesses May Make Prostate Cancer Treatment Unnecessary 2Health News:Iowa VP for Research addresses next-generation supercomputers at congressional hearing 2Health News:Student Suicide May Spur Similar Thoughts in Teens 2
... During the course of a hospitalization, patients are ... to the physician who has primary responsibility for ... details, illegibility, lost paperwork or other problems may ... implemented. , An award-winning study by Martin Were, ...
... Palomar Medical Technologies, Inc. (Nasdaq: PMTI ... for cosmetic treatments, announced today that it will unveil ... Optic(TM), LuxPowR(TM) pulsed-light handpiece and a more powerful Aspire ... of the American Academy of Dermatology (AAD) in San ...
... and Management,s History of Over-Promising & Under-Delivering Bodes ... The LCA-Vision Full Value Committee announced today ... the stockholders of LCA-Vision, Inc.: March 6, 2009Dear ... LCAV, with over 11% of the stock, we ...
... already at the heart of many management and prevention ... of the ESC Council on Cardiovascular Nursing and Allied ... complex needs of people with heart disease. "Of course, ... Deaton, "and we have seen heart disease rates decrease. ...
... Inc. (NYSE Alternext US: ADL), a US-based pharmaceutical ... its Executive Chairman and Chief Executive Officer Mr. ... (SRA) 5th Annual Winter Technology Conference on Monday, ... Technology Conference, Mr. MacLellan will provide details of ...
... PowerPath(R) AP LIS to Interface with BioImagene,s ... March 6 Impac Software, part of ... software solutions for anatomic pathology (AP) laboratories, ... solutions, today announced the development of an ...
Cached Medicine News:Health News:Giving doctors the complete picture 2Health News:Palomar Medical to Debut New Devices and a More Powerful Platform at the American Academy of Dermatology Annual Meeting 2Health News:Palomar Medical to Debut New Devices and a More Powerful Platform at the American Academy of Dermatology Annual Meeting 3Health News:Palomar Medical to Debut New Devices and a More Powerful Platform at the American Academy of Dermatology Annual Meeting 4Health News:Palomar Medical to Debut New Devices and a More Powerful Platform at the American Academy of Dermatology Annual Meeting 5Health News:Palomar Medical to Debut New Devices and a More Powerful Platform at the American Academy of Dermatology Annual Meeting 6Health News:The LCA-Vision Full Value Committee Urges LCA-Vision (NASDAQ: LCAV) Stockholders to Reject the Status Quo 2Health News:The LCA-Vision Full Value Committee Urges LCA-Vision (NASDAQ: LCAV) Stockholders to Reject the Status Quo 3Health News:The LCA-Vision Full Value Committee Urges LCA-Vision (NASDAQ: LCAV) Stockholders to Reject the Status Quo 4Health News:The LCA-Vision Full Value Committee Urges LCA-Vision (NASDAQ: LCAV) Stockholders to Reject the Status Quo 5Health News:Nurses and allied professionals at heart of cardiovascular prevention and management programs 2Health News:Nurses and allied professionals at heart of cardiovascular prevention and management programs 3Health News:AMDL, Inc. to Present at 5th Annual Winter Technology Conference Hosted by Security Research Associates, Inc. 2Health News:AMDL, Inc. to Present at 5th Annual Winter Technology Conference Hosted by Security Research Associates, Inc. 3Health News:Impac Software and BioImagene Develop Workflow Solution for Digital Pathology and the Laboratory Information Systems 2Health News:Impac Software and BioImagene Develop Workflow Solution for Digital Pathology and the Laboratory Information Systems 3
(Date:5/21/2013)... Calif. , May 21, 2013 ... and manufacture of wireless personal healthcare products and ... its reach, announcing the release of two new ... blood pressure monitors and scales: the Wireless Pulse ... (Photo: http://photos.prnewswire.com/prnh/20130521/SF17618 ) ...
(Date:5/21/2013)...  Lehigh Valley Health Network has announced the deployment ... to its existing arsenal of five 5-foot-5 germ-killing UV ... the network, LVHN is now deploying the largest fleet ... and provide the best possible patient care available. ... – the signature product of Memphis ...
(Date:5/21/2013)... VIEW, Calif. , May 21, 2013  Healthcare ... , Russia , ... (BRIC) are realizing there are no shortcuts.  This is ... in the United States.  Companies must change the dialogue ... value, customizing to local needs, and building regional partnerships ...
Breaking Medicine Technology:iHealth Lab adds new products and partners to mobile personal healthcare offering 2iHealth Lab adds new products and partners to mobile personal healthcare offering 3Lehigh Valley Expands Fleet of Superbug-Slaying Robots 2Lehigh Valley Expands Fleet of Superbug-Slaying Robots 3Frost & Sullivan: BRIC is Not Delivering Promises of High Growth in Healthcare Markets 2Frost & Sullivan: BRIC is Not Delivering Promises of High Growth in Healthcare Markets 3Frost & Sullivan: BRIC is Not Delivering Promises of High Growth in Healthcare Markets 4
... Calif. , Aug. 4 To combat the escalating ... New Momentum, the leading SaaS-based anti-counterfeiting solution.  Both companies expect that, ... violators, their New Momentum solution will play a key role in ... , , ...
... Cytel Inc., premier provider of adaptive clinical trial design services and software, recently ... studies based on frequentist or Bayesian methods. , ... The FDA,s recently issued adaptive trial guidelines draft encourages adaptive design ... , , ...
Cached Medicine Technology:Two More Global Pharmaceutical Companies Choose New Momentum to Stop Counterfeits 2Cytel Announces Compass® - The Only Professional Adaptive Trial Software Package for Bayesian or Frequentist Dose-Finding Studies 2Cytel Announces Compass® - The Only Professional Adaptive Trial Software Package for Bayesian or Frequentist Dose-Finding Studies 3
Disposable Microscissors: Horizontal, Curved...
Disposable Microscissors: Horizontal, Straight...
Disposable Microscissors: Vertical, 90...
Low profile, sharp-tipped scissors with a vertical cutting action. Excellent for peeling and cutting fine epiretinal membranes....
Medicine Products: