Navigation Links
JCI online early table of contents: July 1, 2011
Date:7/1/2011

ment of asthma. These data indicate that targeting IFN-gamma could provide a new therapeutic approach to treating asthma if the same IFN-gamma/mast cell axis has a role in the human condition.

TITLE: Identification of an IFN-gamma/mast cell axis in a mouse model of chronic asthma

AUTHOR CONTACT:
Stephen J. Galli
Stanford University School of Medicine, Stanford, California, USA.
Phone: 650.723.7975; Fax: 650.725.6902; E-mail: sgalli@stanford.edu.

Mang Yu
Stanford University School of Medicine, Stanford, California, USA.
Phone: 650.736.0069; Fax: 650.736.0073; E-mail: yumyu@stanford.edu.

View this article at: http://www.jci.org/articles/view/43598?key=40c2869f5f67c2e18553


MUSCLE BIOLOGY: Micro(RNA)managing muscle disease

Centronuclear myopathies are a group of congenital muscular diseases characterized by muscle weakness and abnormal localization of the nucleus in skeletal muscle cells. A team of investigators, led by Eric Olson and Ning Liu, at The University of Texas Southwestern Medical Center, Dallas, has now identified in mice a new molecular regulator of adult skeletal muscle structure and function that seems to act as a modulator of centronuclear myopathy.

MicroRNAs are small RNA molecules that regulate many biological processes by inhibiting the expression of specific genes. Olson, Liu, and colleagues found that mice lacking microRNAs miR-133a-1 and miR-133a-2 develop skeletal muscle abnormalities reminiscent of human centronuclear myopathies. They therefore conclude that, at least in mice, microRNAs miR-133a-1 and miR-133a-2 are essential for multiple facets of skeletal muscle function and maintenance. They further suggest that miR-133a could play a modulatory role in human centronuclear myopathi
'/>"/>

Contact: Karen Honey
press_releases@the-jci.org
734-546-5242
Journal of Clinical Investigation
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8

Related medicine news :

1. JCI online early table of contents: June 13, 2011
2. NYU Langone rheumatologists share insight with online RA community
3. JCI online early table of contents: June 1, 2011
4. CME on atrial fibrillation, interventional cardiology and lipids online at CardioCareLive
5. Watching how cancer patients interact online could help clinicians provide better services
6. JCI online early table of contents: May 9, 2011
7. Online Gaming With Real-World Friends Is Healthier: Study
8. Elsevier launches Exam Consult -- an online exam preparation tool for UK medical school exams
9. New online crisis management and evaluation tool introduced by researchers
10. JCI online early table of contents: April 18, 2011
11. JCI online early table of contents: April 11, 2011
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/12/2014)... The largest pure occupational medicine company in the ... it will be opening its fifth Georgia center in ... Atlanta-based Nova Medical Centers’ locations. The Augusta facility ... and will be open from 8:30 a.m. to 6 ... philosophy of rapid return-to-work and decreased treatment times for ...
(Date:7/11/2014)... 2014 Recently, DressyQuinceanera.com, a well-known wedding ... Dama dresses to its online category. Furthermore, the ... at deeply discounted rates, up to 62% off. , ... equally excellent in terms of quality and style. All ... discounts are also offered for the company’s other items: ...
(Date:7/11/2014)... Ticket Down reports that tickets to the Argentina ... Cup Match between Brazil and Netherlands are in ... Saturday, July 12th at Estadio Nacional de Brasilia Mane Garrincha ... on Sunday, July 13th at Estadio Jornalista Mario Filho - ... 2014 World Cup are guaranteed to be authentic and are ...
(Date:7/11/2014)... 2014 (HealthDay News) -- Reducing the number of deer ... Lyme disease and other tick-borne infections among people, new ... can be manipulated to reduce human interactions with deer, ... disease," the researchers wrote. White-tailed deer are the ... disease to people. The study included nearly all ...
(Date:7/11/2014)... Volunteers from Scientology Churches and ... with drug education lectures, forums and conferences, information stands, ... around the world. , Drug abuse is an international ... Abuse, abuse of alcohol and illicit drugs costs more ... decreased productivity and healthcare. , In the face ...
Breaking Medicine News(10 mins):Health News:Nova Medical Centers To Open New Facility in Augusta, Georgia 2Health News:DressyQuinceanera.com: Beautiful Quinceanera Dama Dresses At Low Prices 2Health News:Argentina vs. Germany World Cup Finals Tickets & Brazil vs. Netherlands 3rd Place World Cup Tickets Are in Huge Demand 2Health News:Scientologists Taking Action against Drug Abuse 2Health News:Scientologists Taking Action against Drug Abuse 3
... Bisphenol A (BPA) is used in the manufacture of plastics ... a tendency to become highly unstable due to break in ... container causing damage to human health. BPA is found to ... and developmental problems. Estrogens is a female sex hormone which ...
... brings joy and excitement to the parents and family members ... birth of baby Maia, after her mother successfully// underwent radiotherapy ... anything come between her baby and self. ... and was staged III Hodgkin’s lymphoma. She was required to ...
... camp is further complicating the relief efforts taken by ... cases have been reported, with the death of a ... of them are children and under surveillance," said Abdul ... said eight of the infected children had already been ...
... Mothers have been known to influence their children in ... been found that their attitude towards eating habits and ... teenagers as well. Perception of the teenager’s mother regarding ... ,A number of genetic and other environmental factors are ...
... being sold to foreigners for human transplantation purposes in ... officials, who have been passive// about the issue for ... of such an inhuman act. ,Despite reports ... strangers (were paid for their donation) and transmission of ...
... to the press about improvising the health care facilities at ... needs more hospitals with ICUs// and ambulance facilities 24-hour health ... , ,He put forth the idea about giving ... authorities. He also mentioned that the chief minister Mr. Nitish ...
Cached Medicine News:Health News:Robotic ovarian transposition helps cancer patient deliver baby 2Health News:Adolescents Influenced By Maternal Attitude Regarding Weight Control 2Health News:Widespread Commercialisation Of Human Organ Donation In China 2
(Date:7/11/2014)... -- Research and Markets ( http://www.researchandmarkets.com/research/tjlw9k/immunoprotein ) has ... Testing Market - Forecasts to 2019: Expected to ... is expected to be valued at USD 4,943.0 ... http://photos.prnewswire.com/prnh/20130307/600769 The ... according to immunoprotein types which include immunoglobulins, complement ...
(Date:7/10/2014)... , 11. Juli 2014  Dilon ... für die molekulare Bildgebung, einschließlich molekularer ... die CE-Zulassung für sein Navigator ® ... Dilon das Produkt jetzt europaweit vertreiben. ... Großteil der europäischen Länder ausgedehnt und ...
(Date:7/10/2014)... 10, 2014 Yesterday, former Congressman ... device manufacturing facility. Rep. Kennedy and Dick ... facilitate cutting-edge research in neurological disease and treatment. ... health advocate, Garen Staglin , created One ... fundamental changes that will radically accelerate the development ...
Breaking Medicine Technology:Immunoprotein Diagnostic Testing Market - Forecasts to 2019: Expected to grow at the highest CAGR of 6% and is expected to be valued at USD 4,943.0 million 2Dilon erhält CE-Zulassung für sein Navigator-Gamma-Sondensystem 2Representative Patrick Kennedy visits Moberg's medical device facility to discuss improvement in brain injury care 2
... Reportlinker.com announces that a new market ... Respiratory Devices - Global ... to 2016 http://www.reportlinker.com/p0240243/Respiratory-Devices---Global-Pipeline-Analysis-Opportunity-Assessment-and-Market-Forecasts-to-2016.html ... Global Pipeline Analysis, Opportunity Assessment and Market ...
... 14 AAIPharma Services Corp., a leading provider of ... announced today that it has appointed Patrick D. Walsh ... equity firm focused exclusively on health care that acquired ... company in 2009, was instrumental in recruiting Mr. Walsh ...
Cached Medicine Technology:Reportlinker Adds Respiratory Devices - Global Pipeline Analysis, Opportunity Assessment and Market Forecasts to 2016 2Reportlinker Adds Respiratory Devices - Global Pipeline Analysis, Opportunity Assessment and Market Forecasts to 2016 3AAIPharma Services Corp. Names Patrick Walsh Chief Executive Officer 2AAIPharma Services Corp. Names Patrick Walsh Chief Executive Officer 3
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: