Navigation Links
JCI online early table of contents: July 1, 2011
Date:7/1/2011

l: lelievre@inci-cnrs.unistra.fr.

View this article at: http://www.jci.org/articles/view/43824?key=1236357151332f9ec680


EDITOR'S PICK: T-ing up a new target for Parkinson disease treatment

Parkinson disease (PD) affects 1-2% of the population over the age of 65 years. It results from loss or loss of function of nerve cells in the brain that coordinate movement. As a result, the hallmark symptoms of PD are trembling in hands, arms, legs, jaw, and face; stiffness of the limbs and trunk; slowness of movement; and impaired balance and coordination. There is no cure for PD, but symptoms can be alleviated with a variety of drugs. A team of researchers, led by Chung-Chin Kuo, at National Taiwan University College of Medicine, Taiwan, has now shown that pharmacological blockade of T-type calcium channels reduces deficiencies in the ability to move normally in a rat model of PD. This, and other observations, leads them to suggest that targeting T-type calcium channels could provide a new approach to treating individuals with PD.

TITLE: Modulation of subthalamic T-type Ca2+ channels remedies locomotor deficits in a rat model of Parkinson disease

AUTHOR CONTACT:
Chung-Chin Kuo
National Taiwan University College of Medicine, Taipei, Taiwan.
Phone: 886.2.23123456, ext. 88236; Fax: 886.2.23964350; E-mail: chungchinkuo@ntu.edu.tw.

View this article at: http://www.jci.org/articles/view/46482?key=b7b5f0630636ab8bf422


ONCOLOGY: Role for stem cells in tumor development

Ovarian cancer is the fifth most common cancer among women. New research, performed by Ronald Buckanovich and colleagues, at the University of M
'/>"/>

Contact: Karen Honey
press_releases@the-jci.org
734-546-5242
Journal of Clinical Investigation
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8

Related medicine news :

1. JCI online early table of contents: June 13, 2011
2. NYU Langone rheumatologists share insight with online RA community
3. JCI online early table of contents: June 1, 2011
4. CME on atrial fibrillation, interventional cardiology and lipids online at CardioCareLive
5. Watching how cancer patients interact online could help clinicians provide better services
6. JCI online early table of contents: May 9, 2011
7. Online Gaming With Real-World Friends Is Healthier: Study
8. Elsevier launches Exam Consult -- an online exam preparation tool for UK medical school exams
9. New online crisis management and evaluation tool introduced by researchers
10. JCI online early table of contents: April 18, 2011
11. JCI online early table of contents: April 11, 2011
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/14/2014)... orphaned by HIV/AIDS in South Africa may provide insight ... behavior issues in other areas of the world, which ... that could lead to successful interventions. , A ... United Nations mentions that due to the HIV/AIDS pandemic, ... African, children are at an increased risk for mental ...
(Date:4/14/2014)... A new study shows that moderate to severe ... risk of stroke, cancer and death. , Results of ... to severe obstructive sleep apnea were four times more ... times more likely to have a stroke (HR = ... (HR = 3.4), and 2.5 times more likely to ...
(Date:4/14/2014)... Dallas study involving serious youth offenders, the answer to one ... seven years: "How long do you think you,ll live?", According ... offending over time., Author Dr. Alex Piquero said the study ... of them offend at very high rates and commit more ... much later in life offend much less., "In a lot ...
(Date:4/14/2014)... with symptoms increasing dramatically during some of the most important ... has found. , Depressive symptoms increased on average by 68 ... young men, who were around 25 years old when they ... their children. The results of the study were published April ... is the first to identify when young fathers are at ...
(Date:4/14/2014)... Lower weight babies and babies who aren,t breastfed ... risk of developing chronic inflammation and related health ... study. , "There were good reasons to hypothesize ... inflammation in adulthood," says Thomas McDade (Northwestern University), ... in the Child & Brain Development program. "It ...
Breaking Medicine News(10 mins):Health News:Researchers identify children with emotional behavior difficulties 2Health News:Researchers identify children with emotional behavior difficulties 3Health News:Study links severe sleep apnea to increased risk of stroke, cancer and death 2Health News:UT Dallas study: Youth who fail to envision future commit more crimes 2Health News:Young dads at high risk of depression, too 2Health News:Low birth weight, less breastfeeding create later health risks 2
... JANEIRO, Brazil, March 11 Amilpar,(BOVESPA: AMIL3, Bloomberg: ... organization in Brazil, announced today its consolidated,results for ... 2007. The Company,s,operational and financial information is presented ... accordance with Brazilian Corporate Law and the,Accounts Chart ...
... Wilkins Speaks on Behalf of People with ... Diabetes During Congressional Briefing, WASHINGTON, March ... Members of Congress to support,a bill that will develop a ... Wilkins was joined today at a briefing on Capitol,Hill by ...
... cells in the human brain are not nerve cells, but supporting ... and play an important role in the wound reaction that occurs ... in the brains of mice and men originate from, and which ... group of Prof. Dr. Magdalena Gtz is able to show that ...
... Inc.,(NYSE: RBN ) announced today that it will ... the period ended February 29, 2008, after,market close on ... conference,call will be held at 2:00 p.m., EDT on ... Chief Executive Officer, and Christopher M. Hix,Vice President and ...
... COLUMBUS, Ohio, March 11 Mettler-Toledo,International Inc. (NYSE: ... the Lehman Brothers Global Healthcare Conference in Miami,on Tuesday, ... hear a live,webcast of the presentation, visit the investor ... . A replay of the webcast will be,available for ...
... (March 11, 2008) -- A test that profiles molecular biomarkers ... Parkinson,s disease, new research shows. , The screen relies on ... alterations form a unique pattern in people with Parkinson,s disease, ... Cornell Medical College in New York City. , They published ...
Cached Medicine News:Health News:Amilpar Revenues Increase by 32% and EBITDA Doubles in 2007 2Health News:Diabetes Advocates Urge Members of Congress to Support Creation of National Diabetes Coordinator 2Health News:Diabetes Advocates Urge Members of Congress to Support Creation of National Diabetes Coordinator 3Health News:First early-detection blood test for Parkinson's shows promise 2Health News:First early-detection blood test for Parkinson's shows promise 3
(Date:1/14/2014)... 14, 2014   NuAire , a manufacturer of ergonomically ... agreement with Hitachi Koki of Japan ... centrifuges in North America . NuAire will ... United States and Canada ... options and accessories, training, pricing, as well as after sale ...
(Date:1/14/2014)... N.Y. , Jan. 14, 2014   Oligomerix, ... development of disease modifying therapeutics for Alzheimer,s disease ... relocation of its corporate headquarters to ... 2014 and expanded lease agreement for additional laboratory ... Oligomerix, which is focused on the development of ...
(Date:1/14/2014)... Jan. 14, 2014   Evidera , a ... industry, announced that the Center for Drug Evaluation ... has released its first draft qualification guidance document ... development: Qualification of Exacerbations of Chronic Pulmonary ... Acute Bacterial Exacerbation of Chronic Bronchitis in Patients ...
Breaking Medicine Technology:NuAire announces sales and service of Hitachi Koki centrifuges in North America 2Oligomerix Relocates Corporate Headquarters and Secures Additional Laboratory Space from New York Medical College 2Evidera Announces Release of FDA Draft Guidance on Use of the "EXACT" to Measure Symptoms of COPD Exacerbations 2Evidera Announces Release of FDA Draft Guidance on Use of the "EXACT" to Measure Symptoms of COPD Exacerbations 3Evidera Announces Release of FDA Draft Guidance on Use of the "EXACT" to Measure Symptoms of COPD Exacerbations 4
Jaffe tying forceps is very delicate with smooth jaws, straight, 6 mm long platform. For 8-0 to 11-0 sutures....
Straight heavy shafts with 7 mm tying surface. Wide serrated handle, polished finish. Overall length 4.2 inches....
Tying forceps with 6.5 mm tying platform. Round handle with flats provide flexibility of round handle with the stability of a flat handle. Straight shafts. Overall length 3.9 inches....
Curved shafts with 4 mm tying platform. Serrated handle with dull finish. Manufactured in titanium. Overall length 3.3 inches....
Medicine Products: