Navigation Links
JCI online early table of contents: Jan. 12, 2009
Date:1/12/2009

EDITOR'S PICK: Opiods provide relief from neuropathic pain

The pain that is associated with injury to nerves, such as caused by the trauma of amputation, entrapment, and compression, is known as neuropathic pain. It can be extremely debilitating, and treatments show limited or no effectiveness. Nerve injury underlying neuropathic pain is associated with an inflammatory response, and immune cells are thought to be contributors to the pain. However, Halina Machelska and colleagues, at Freie Universitt Berlin, Germany, have now shown that in a mouse model of neuropathic pain, a substantial proportion of the immune cells at the site of nerve injury produce chemicals known as opiods that markedly reduce the symptoms of neuropathic pain. The authors therefore suggest that selectively targeting opioid-containing immune cells at sites of nerve injury could provide natural pain relief and offer a novel approach for neuropathic pain.

TITLE: Immune cellderived opioids protect against neuropathic pain in mice

AUTHOR CONTACT:
Halina Machelska
Freie Universitt Berlin, Medizinische Fakultt Charit-Universittsmedizin Berlin, Berlin, Germany.
Phone: 49-30-8445-3851; Fax: 49-30-8445-3826; E-mail: halina.machelska@charite.de.

View the PDF of this article at: https://www.the-jci.org/article.php?id=36246


IMMUNOLOGY: New effect on the immune system of Vitamin D3

A group of proteins known as TLRs recognize molecules produced by microorganisms such as bacteria and viruses and trigger an immune response. Several approaches to targeting one of these proteins, TLR9, are being developed to help boost the efficacy of antitumor immunotherapies and vaccines. Catherine Hawrylowicz and colleagues, at King's College London, United Kingdom, have now provided new insight into how drugs that stim
'/>"/>

Contact: Karen Honey
press_releases@the-jci.org
215-573-1850
Journal of Clinical Investigation
Source:Eurekalert

Page: 1 2 3 4 5

Related medicine news :

1. HIV denialists spread misinformation online -- consequences could be deadly; and more
2. Consequences of online HIV denial; and more
3. Online Epidemic Gives Clues to Bird Flu Spread
4. MedHelp to Add Top Stanford Surgeons and Specialized Forums to Online Health Community
5. Online Celebrity Shoe Charity Auction for Womens Heart Health Opens Bidding
6. Syndicom to Launch Online Community for DePuy Spine
7. Elder Caregiving Site ShirleyBOARD.com Wins WebAward for Outstanding Online Community
8. Peer-Reviewed, Online Database Showcases Local, County and State Pandemic Planning
9. CIGNA Behavioral Health Offers Members Online Provider Profiles
10. Dynamic Energy Systems Goes Online and On-Demand
11. North Shore-LIJ Health System Begins Online Posting of Hospital Infection Rates, Other Performance Information
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... Delhi, India (PRWEB) August 29, 2014 RBS ... named Remove Scam Book. The service is to help ... negative reviews against them on Scam Book. The service would ... results and make Scam Book complaints fully invisible on Google. ... the service. , On being asked how company can ...
(Date:8/29/2014)... (PRWEB) August 29, 2014 A home should be ... up if unaddressed. That’s why Amica Insurance is sharing some tips ... Safety Council suggests taking the following safety measures: , Kitchen, ... – in their original containers, and keep them away from food. ... wall bracket near an exit. , Bathroom , ...
(Date:8/29/2014)... across the Arabian Peninsula and spread to Europe several ... of several hundred people since its discovery in 2012. ... how easily the pathogen spreads from human to human. ... the University of Bonn have now come to the ... transmission is low. Still, a third of infected persons ...
(Date:8/29/2014)... Glendale Botox experts at Glenoaks ... throughout the month of September. This special offer features 10 ... of Juvederm. Patients can take advantage of this special offer ... Botox experts will work with patients to determine if Botox ... is Botox? , Botox is a treatment made from ...
(Date:8/29/2014)... VHA Central Atlantic recognized Novant ... care, honoring nine facilities for meeting or exceeding national ... Novant Health, providing quality, affordable healthcare for our communities ... MD, executive vice president and chief medical officer. “These ... experience for each and every one of our patients.” ...
Breaking Medicine News(10 mins):Health News:RBS Reputation Management Announces a New Online Reputation Management Service 2Health News:Improve Home Safety with Tips from Amica Insurance 2Health News:MERS: Low transmissibility, dangerous illness 2Health News:MERS: Low transmissibility, dangerous illness 3Health News:Glenoaks Laser Center is Now Offering a Special Promotion on Botox for the Month of September 2Health News:Novant Health Recognized for Excellence in Clinical Care 2Health News:Novant Health Recognized for Excellence in Clinical Care 3
... Poster Presented at Annual Meeting of the American Academy of ... ... 11 NeoStrata today released new,clinical research that validates the benefits ... as a complement to,medical anti-aging treatments such as lasers and microdermabrasion. ...
... research from the UC Davis M.I.N.D. Institute and Center ... the blood of mothers of children with autism bind ... The study authors also found that the reaction was ... form of autism, which occurs when a period of ...
... Deerfield Spa is pleased,to announce the appointment of ... Science., "Jeanine brings outstanding credentials to Deerfield,s ... experience enable her,to fine tune our offerings so ... regimen at the spa, but also learn skills ...
... MyClyns(TM) - the Only Non-Alcohol Product that can be ... Sprayed Directly into the ... today that its revolutionary new product for use after a,potential pathogenic ... upgraded its web site, added a customer,service center and deployed regional ...
... New Patent Expands Geographic Coverage, ... Inc. (OTC Bulletin Board: CARN) today ... granted patent application No. 200600484, titled,"Delivery ... Comprising Anionic,Polysaccharides," relating to the Company,s ...
... University of Oregon scientists say they,ve discovered a ... birth defect in humans that has challenged medical ... zebrafish are present in humans and other vertebrates. ... 10-member research team isolated a disruption in early ...
Cached Medicine News:Health News:NeoStrata Research Validates Anti-Aging Benefits of At-Home AHA Peels As Complement to In-Office Non-Invasive Cosmetic Procedures 2Health News:Some cases of autism may be traced to the immune system of mothers during pregnancy 2Health News:Some cases of autism may be traced to the immune system of mothers during pregnancy 3Health News:Some cases of autism may be traced to the immune system of mothers during pregnancy 4Health News:Deerfield Spa Appoints New Fitness Director 2Health News:First Responders Acquire Revolutionary MyClyns(TM) Protective Spray 2Health News:First Responders Acquire Revolutionary MyClyns(TM) Protective Spray 3Health News:Carrington's DelSite Drug Delivery Technology Granted Patent From Eurasian Patent Office 2Health News:Carrington's DelSite Drug Delivery Technology Granted Patent From Eurasian Patent Office 3Health News:Oregon researchers discover a mechanism leading to cleft palate 2
(Date:8/28/2014)... NEW YORK , Aug. 28, 2014 /PRNewswire/ ... report is available in its catalogue: ... http://www.reportlinker.com/p02343464/North-America-Laparoscopes-Market-Outlook-to-2020.html North ... GlobalData,s new report, "North America Laparoscopes Market ... the North America Laparoscopes market. The report provides ...
(Date:8/28/2014)... , Aug. 28, 2014 /PRNewswire-iReach/ -- CountryFocus: ... Poland (Photo - ... CountryFocus: Healthcare, Regulatory and Reimbursement Landscape Poland " ... key trends in the healthcare market and provides ... healthcare infrastructure. Most importantly, the report provides valuable ...
(Date:8/28/2014)... Tianyin Pharmaceutical Co., Inc. (NYSE Amex: ... specializes in patented biopharmaceutical, modernized traditional Chinese medicine ... today updates the timeline for the GMP certification ... The Company is scheduled to submit the ... & Drug Administration,s (CFDA) review in the week ...
Breaking Medicine Technology:North America Laparoscopes Market Outlook to 2020 2North America Laparoscopes Market Outlook to 2020 3North America Laparoscopes Market Outlook to 2020 4North America Laparoscopes Market Outlook to 2020 5North America Laparoscopes Market Outlook to 2020 6North America Laparoscopes Market Outlook to 2020 7North America Laparoscopes Market Outlook to 2020 8North America Laparoscopes Market Outlook to 2020 9North America Laparoscopes Market Outlook to 2020 10North America Laparoscopes Market Outlook to 2020 11Poland & Turkey Pharmaceutical Market worth $15 billion & $21.5 billion Respectively by 2020 2Poland & Turkey Pharmaceutical Market worth $15 billion & $21.5 billion Respectively by 2020 3Poland & Turkey Pharmaceutical Market worth $15 billion & $21.5 billion Respectively by 2020 4Poland & Turkey Pharmaceutical Market worth $15 billion & $21.5 billion Respectively by 2020 5TPI Submits Dataset for GMP Inspection at Qionglai Facility (QLF) 2
... Continues Biocatalysis Business Growth With a Further $4m R&D Investment -- CRAIGAVON, Northern Ireland, October 7, 2010 ... ... if (typeof(lpUnit)==,undefined,) var lpUnit=,PRN,; --> ... = function(data) { var s = ,; var first_result; // Results are keyed by longUrl, so we ...
... N.J., Oct. 7 Novartis Pharmaceuticals Corporation today ... Gilenya™ (fingolimod) 0.5 mg daily, a first-line oral ... was approved by the US Food and Drug ... For people with MS and healthcare professionals seeking ...
Cached Medicine Technology:Almac Continues Biocatalysis Business Growth With a Further $4m R&D Investment 2Almac Continues Biocatalysis Business Growth With a Further $4m R&D Investment 3Almac Continues Biocatalysis Business Growth With a Further $4m R&D Investment 4Almac Continues Biocatalysis Business Growth With a Further $4m R&D Investment 5Almac Continues Biocatalysis Business Growth With a Further $4m R&D Investment 6Almac Continues Biocatalysis Business Growth With a Further $4m R&D Investment 7Novartis Committed to Supporting Patients and Healthcare Professionals with Education Programs and Support Services that Enhance Access to Gilenya 2Novartis Committed to Supporting Patients and Healthcare Professionals with Education Programs and Support Services that Enhance Access to Gilenya 3Novartis Committed to Supporting Patients and Healthcare Professionals with Education Programs and Support Services that Enhance Access to Gilenya 4Novartis Committed to Supporting Patients and Healthcare Professionals with Education Programs and Support Services that Enhance Access to Gilenya 5Novartis Committed to Supporting Patients and Healthcare Professionals with Education Programs and Support Services that Enhance Access to Gilenya 6Novartis Committed to Supporting Patients and Healthcare Professionals with Education Programs and Support Services that Enhance Access to Gilenya 7
... Our breadth of infectious disease ELISA products ... With standard assay protocols for faster integration ... ELISA products provide increased reliability and run-to-run ... antibody detection assays for a wide range ...
... Our breadth of infectious disease ELISA products ... With standard assay protocols for faster integration ... ELISA products provide increased reliability and run-to-run ... antibody detection assays for a wide range ...
... ELISA products make us a leader in ... faster integration into the busy laboratory, our ... and run-to-run consistency. Our Infectious Disease ELISA ... wide range of serological assays including ToRCH, ...
... disease ELISA products make us a leader ... for faster integration into the busy laboratory, ... reliability and run-to-run consistency. Our Infectious Disease ... a wide range of serological assays including ...
Medicine Products: