Navigation Links
JCI online early table of contents: Feb. 15, 2010
Date:2/15/2010

ice lacking the protein PTP1B only in POMC neurons (POMC-Ptp1b/ mice) had decreased fat content and expended more energy than normal mice. By contrast, mice lacking the protein SHP2 only in POMC neurons (POMC-Shp2/ mice) had increased fat content and expended less energy than normal mice. Underlying these data was the fact that POMC-Ptp1b/ mice were able to control glucose levels in their blood easily, whereas POMC-Shp2/ mice were not. These data indicate that PTP1B and SHP2 have reciprocal roles in POMC-neuron regulation of energy balance, at least in mice.

TITLE: PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice

AUTHOR CONTACT:

Kendra K. Bence
University of Pennsylvania, Philadelphia, PA, USA.
Phone: 215.746.2998; Fax: 215.573.5186; E-mail: kbence@vet.upenn.edu.

View this article at: http://www.jci.org/articles/view/39620?key=165b87c2feba4a3c8de1


'/>"/>
Contact: Karen Honey
press_releases@the-jci.org
215-573-1850
Journal of Clinical Investigation
Source:Eurekalert

Page: 1 2 3 4 5 6

Related medicine news :

1. HIV denialists spread misinformation online -- consequences could be deadly; and more
2. Consequences of online HIV denial; and more
3. Online Epidemic Gives Clues to Bird Flu Spread
4. MedHelp to Add Top Stanford Surgeons and Specialized Forums to Online Health Community
5. Online Celebrity Shoe Charity Auction for Womens Heart Health Opens Bidding
6. Syndicom to Launch Online Community for DePuy Spine
7. Elder Caregiving Site ShirleyBOARD.com Wins WebAward for Outstanding Online Community
8. Peer-Reviewed, Online Database Showcases Local, County and State Pandemic Planning
9. CIGNA Behavioral Health Offers Members Online Provider Profiles
10. Dynamic Energy Systems Goes Online and On-Demand
11. North Shore-LIJ Health System Begins Online Posting of Hospital Infection Rates, Other Performance Information
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/4/2015)... (PRWEB) , ... August 04, 2015 , ... One of ... interviews to discuss his new book, The Pain Antidote , which provides strategies ... of Las Vegas Recovery Center’s Chronic Pain Treatment Program, wrote the book in conjunction ...
(Date:8/4/2015)... ... 04, 2015 , ... 24/7 Care At Home , a provider of ... today announced that the U.S. Department of Veteran’s Affairs (VA) has awarded its agency ... is well on the path to meeting the aspirational goals the VA promotes each ...
(Date:8/4/2015)... ... 04, 2015 , ... Increasingly, patients are researching online to ... In an effort to share more and better information with these savvy and ... share patient satisfaction ratings and comments about its doctors and advanced practice providers. ...
(Date:8/4/2015)... ... August 04, 2015 , ... SanusEO, the healthcare industry ... its executive leadership team as Senior Vice President of Sales and Marketing. Mr. ... expanding global markets with a special emphasis on the healthcare industry. , Today, ...
(Date:8/4/2015)... NJ (PRWEB) , ... August 04, 2015 , ... Montclair ... Arts and Health, the first of its kind in New Jersey, which starting this ... of the Arts and Graduate School partnered with Atlantic Health System, one of the ...
Breaking Medicine News(10 mins):Health News:Medical Expert's New Book Offers Help for Chronic Pain Sufferers 2Health News:Medical Expert's New Book Offers Help for Chronic Pain Sufferers 3Health News:24/7 Care At Home Receives Two Stars from the VA 2Health News:24/7 Care At Home Receives Two Stars from the VA 3Health News:UPMC 1st in Pa. to Share Provider Ratings 2Health News:UPMC 1st in Pa. to Share Provider Ratings 3Health News:SanusEO Hires Healthcare Technology Executive Bruce McCalley As Senior Vice President of Sales & Marketing 2Health News:SanusEO Hires Healthcare Technology Executive Bruce McCalley As Senior Vice President of Sales & Marketing 3Health News:Atlantic Health System & Montclair State University Launch Graduate Program in Arts & Health 2Health News:Atlantic Health System & Montclair State University Launch Graduate Program in Arts & Health 3
... all Sites from a Single ... ... chosen multiple products from Sage Software - including the,Intergy by Sage Practice ... the,patient experience. Previously, Digestive Specialists used The Medical,Manager by Sage., "We ...
... Biosciences, Inc.,(Nasdaq: RDEA ), a company focused ... for the treatment of HIV, cancer and,inflammatory diseases, ... key milestones in 2008 for its clinical,development programs, ... provided financial guidance for 2008., "During 2007, ...
... from Stanford University, ... Diego State University, CENTER VALLEY, Pa., March ... opto-digital solutions in healthcare,life science and consumer electronics ... Innovation Award Program: Tom Byers, Ph.D. and Tina,Seelig, ...
... CHICAGO, March 24 Linden LLC, a health care ... of a controlling,interest in its portfolio company, Ranir LLC, ... P. Kiphart. In addition to being a private,investor, Mr. ... Company.,Linden acquired Ranir in April 2005 and will maintain ...
... HealthMEDX, Inc. (HMX),the leading provider of Web-based ... has partnered with Silverchair Learning Systems to,offer ... Silverchair,s Learning Management System is a ... that delivers, tracks,and reports on educational programs ...
... finds they,re not getting needed screenings for breast and cervical ... review of 32 studies suggests that obese women -- particularly ... screenings for breast and cervical cancer. , No one ... avoid mammograms or Pap smears. And it,s not known why ...
Cached Medicine News:Health News:Multi-site Gastro Practice Chooses Intergy by Sage Practice Management System 2Health News:Ardea Biosciences Reports Progress of Clinical Development Programs; Provides 2008 Outlook; Announces 2007 Financial Results and Provides 2008 Financial Guidance 2Health News:Ardea Biosciences Reports Progress of Clinical Development Programs; Provides 2008 Outlook; Announces 2007 Financial Results and Provides 2008 Financial Guidance 3Health News:Ardea Biosciences Reports Progress of Clinical Development Programs; Provides 2008 Outlook; Announces 2007 Financial Results and Provides 2008 Financial Guidance 4Health News:Ardea Biosciences Reports Progress of Clinical Development Programs; Provides 2008 Outlook; Announces 2007 Financial Results and Provides 2008 Financial Guidance 5Health News:Ardea Biosciences Reports Progress of Clinical Development Programs; Provides 2008 Outlook; Announces 2007 Financial Results and Provides 2008 Financial Guidance 6Health News:Olympus Announces 2008 Winners of Olympus Innovation Awards 2Health News:Olympus Announces 2008 Winners of Olympus Innovation Awards 3Health News:Olympus Announces 2008 Winners of Olympus Innovation Awards 4Health News:Linden Announces Sale of Ranir to Kayak Holdings 2Health News:Linden Announces Sale of Ranir to Kayak Holdings 3Health News:HealthMEDX Partners With Silverchair Learning Systems 2Health News:Obese Women Less Likely to Be Tested for Some Cancers 2
(Date:8/4/2015)... -- Research and Markets ( ... PharmaBiotech,s new report "Animal Biotechnology - Technologies, ... This report describes and evaluates animal biotechnology ... as well as improvement in food production. Knowledge ... of biotechnology to manage genetic disorders and improve ...
(Date:8/4/2015)... Pa. , Aug. 4, 2015 Among ... prescription medications, yet only half of consumers surveyed are ... percent have ever used use them, according to findings ... , a community service partnership focused on improving the ... The online survey polled 1,000 men and women, ...
(Date:8/3/2015)... 4, 2015   The Intellectual Property and ... leading provider of intelligent information for businesses and ... CMR Pharmaceutical R&D Factbook , the biopharmaceutical industry,s ... around declines in R&D, the analysis identifies a ... milestone and forecasts sales to reach $1.3 trillion ...
Breaking Medicine Technology:Animal Biotechnology 2014-2024 - 2015 Technologies, Markets and Companies Analysis 2Animal Biotechnology 2014-2024 - 2015 Technologies, Markets and Companies Analysis 3New Study Finds Consumers are Leaving Money at the Pharmacy 2New Study Finds Consumers are Leaving Money at the Pharmacy 3Pharma Sales to Grow Beyond $1 Trillion 2
... June 30, 2011 UCB and Harvard University officially ... that took place in Boston last night in the ... (Photo: http://photos.prnewswire.com/prnh/20110630/NY28450 ) ... industry and academia, with Harvard scientists continuing their research ...
... -- Golden Meditech Holdings Limited ("Golden ... "Group," - 801.HK; 910801.TW), a leading integrated healthcare ... Group,s annual results for the year ended 31 ... core businesses reported total turnover of HK$328,066,000, 15% ...
Cached Medicine Technology:UCB Launches Research Alliance with Harvard University 2UCB Launches Research Alliance with Harvard University 3Golden Meditech FY2010-11 Annual Results 2Golden Meditech FY2010-11 Annual Results 3
... individually adjusted for perfect focus where it's ... paper. This, along with Keeler's wide angle ... whatever the patient's pupil size, you will ... view. Lithium-ion technology provides a longer life ...
... individually adjusted for perfect focus where it's ... paper. This, along with Keeler's wide angle ... whatever the patient's pupil size, you will ... view. Lithium-ion technology provides a longer life ...
A full function instrument at an economical price....
... superior aspherical optics. Includes XHL halogen bulb. ... by means of the aspherical optical system ... Beta 200 allows you to view the ... retina even with a small pupil. Conventional ...
Medicine Products: