Navigation Links
JCI online early table of contents: Dec. 19, 2011
Date:12/19/2011

factor link to breast cancer

The growth factor IGF-1 has been implicated in the development of breast cancer. A team of researchers led by Robin Fuchs-Young, at The University of Texas M.D. Anderson Cancer Center, Smithville, has now demonstrated in mice that the level of expression of the protein estrogen receptor alpha (ER-alpha) on mammary gland cells influences whether IGF-1 can promote breast cancer. Fuchs-Young and colleagues therefore suggest that prepubertal and postmenopausal women are likely to be most susceptible to the potential breast cancerpromoting effects of increased levels of IGF-1, since these are the times in a woman's life when ER-alpha levels are highest.

TITLE: Developmental stage determines estrogen receptor alpha expression and nongenomic mechanisms that control IGF-1 signaling and mammary proliferation

AUTHOR CONTACT:
Robin Fuchs-Young
The University of Texas M.D. Anderson Cancer Center, Smithville, Texas, USA.
Phone: 512-237-9547; Fax: 512-237-6440; E-mail: rfyoung@mdanderson.org.

View this article at: http://www.jci.org/articles/view/42204?key=7e26e09e330e04540afb

METABOLIC DISEASE: Heparan sulfate: protecting the cells destroyed in type 1 diabetes

Type 1 diabetes is a lifelong disease characterized by high levels of sugar (glucose) in the blood. It is caused by the patient's immune system attacking and destroying the cells in their pancreas that produce the hormone insulin, which regulates blood glucose levels. Surprisingly, little is known about the mechanisms regulating the sensitivity and resistance of these cells, which are known as beta-cells, to immune system attack. Now, Charmaine Simeonovic and colleagues, at The Australian National University, Australia, have determined that the molecule heparan sulfate is essential for mouse bet
'/>"/>

Contact: Karen Honey
press_releases@the-jci.org
734-546-5242
Journal of Clinical Investigation
Source:Eurekalert

Page: 1 2 3 4 5 6 7

Related medicine news :

1. Online guide helps health organizations adopt electronic health records
2. JCI online early table of contents: Dec. 12, 2011
3. JCI online early table of contents: Nov. 21, 2011
4. Bullying Moves From Online to Text-Messaging: Study
5. JCI online early table of contents: Nov. 14, 2011
6. JCI online early table of contents: Nov. 7, 2011
7. Online Forums Can Help Women Cope With Pregnancy Loss
8. Parents who go online for pediatric health information are open to doctors website recommendations
9. Survey reveals reasons doctors avoid online error-reporting tools
10. Penn-developed online informed consent tool could boost number of patients in cancer clinical trials
11. New online learning module gives children of domestic violence a voice
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/4/2015)... ... September 04, 2015 , ... Keeping mold top of ... the home is quite common. Mold can grow anywhere - on carpet, clothing, food, ... Checking for excessive moisture and water in the home is key to preventing mold ...
(Date:9/4/2015)... ... September 04, 2015 , ... Many consumers are looking for a quick and convenient ... solution. , The patent-pending K Med Cups provide a quick and simple way to brew ... a cold, flu or cough. As a result, they enhance comfort and health. The invention ...
(Date:9/4/2015)... (PRWEB) , ... September 04, 2015 , ... Having access ... This has led to an increasing amount of unnecessary emergency room visits which affects ... and taxes the country’s health bill. Fortunately, a solution to alleviate this problem has ...
(Date:9/4/2015)... ... September 04, 2015 , ... Compliance officers ... settlements under the Stark physician self-referral law. “Stark Law DOs and DON’Ts: ... Atlantic Information Services, Inc. (AIS), will detail which deals are attracting the most ...
(Date:9/4/2015)... GENEVA, IL (PRWEB) , ... September 04, 2015 , ... ... in Geneva, IL hosting Generation Rescue’s A Night of Hope event supporting families affected ... Ed French and Rowena and Joe Salas, joined together at the Oscar Swan Inn ...
Breaking Medicine News(10 mins):Health News:September is Mold Awareness Month 2Health News:September is Mold Awareness Month 3Health News:September is Mold Awareness Month 4Health News:Redesigned Packaging for Powdered Medicinal Mix Invented by InventHelp® Client (CBA-2637) 2Health News:Telemedicine Platform DocChat Announces Launch Offering a Way for Patients to Consult Doctors and Receive Prescriptions 24/7 2Health News:Telemedicine Platform DocChat Announces Launch Offering a Way for Patients to Consult Doctors and Receive Prescriptions 24/7 3Health News:Sept. 17 Webinar to Offer Best Practices for Physician Contracts 2Health News:Jenny McCarthy & Donnie Wahlberg Help Raise Over $200,000 For Generation Rescue’s ‘Night Of Hope’ Chicago Charity Event 2
... Dotinga HealthDay Reporter , WEDNESDAY, April 4 (HealthDay ... HIV vaccine failed to protect most people who received it, ... vaccine efforts. Scientists believe an HIV vaccine, designed to ... several years away. Tests of experimental vaccines have largely been ...
... criticized as having misogynistic messages and images. While more ... "brands" in recent years, critics argue that many of ... with regard to race, gender and sexuality in popular ... in the University of Missouri School of Journalism, and ...
... MA (April 4, 2012)-- IntegraGen, Inc., a biotechnology company ... of the ARISk Risk Assessment Test, a gender specific, ... associated with Autism Spectrum Disorder (ASD). The test is ... from multiplex familiessiblings of children with ASD who are ...
... By Steven Reinberg HealthDay Reporter , WEDNESDAY, ... appears to lengthen the lives of patients with a ... a small phase 2 trial. The drug, belagenpumatucel-L ... cell lung cancer and increased the five-year survival rate ...
... cancer (IBC) is a very aggressive, often misunderstood type of ... with other types of breast cancer. The five-year survival rate ... rate for other types of breast cancer. The reason for ... often spreads quickly to other parts of the body, including ...
... (HealthDay News) -- ,People with metal-on-metal hip replacements do not ... years after they receive the device, according to a new ... researchers at the Universities of Bristol and Exeter in the ... Registry of England and Wales, which contains records on more ...
Cached Medicine News:Health News:From a Failed Vaccine, New Insights Into Fighting HIV 2Health News:Sexual objectification of female artists in music videos exists regardless of race, MU study finds 2Health News:IntegraGen launches ARISk test, a genetic screening tool for autism in high-risk children 2Health News:IntegraGen launches ARISk test, a genetic screening tool for autism in high-risk children 3Health News:Early Study Finds Some Promise for Lung Cancer Vaccine 2Health News:Researchers develop a new cell and animal model of inflammatory breast cancer 2Health News:Researchers develop a new cell and animal model of inflammatory breast cancer 3Health News:No Added Cancer Risk From Hip Replacement Materials: Study 2
(Date:9/3/2015)... 3, 2015 With a population of more ... and therefore also its single largest potential market for ... has led all major world economies in the average ... and government health expenditures. As an in vitro diagnostics ... of the United States, western European countries, and Japan. ...
(Date:9/3/2015)... About cardiovascular implants ... or blockage of blood vessels. Cardiac disease is ... cholesterol, and high blood pressure. Coronary artery disease, ... failure are some of the major cardiac diseases. ... coronary arteries, is one of the most common ...
(Date:9/3/2015)... Sept. 3, 2015  WellCare Health Plans, Inc. (NYSE: ... , senior vice president and chief financial officer, is ... Healthcare Conference on Wednesday, September 9, 2015, at 9:25 ... webcast live. In addition, a replay of the webcast ... broadcast. Both the live broadcast and the replay will ...
Breaking Medicine Technology:IVD in China 2IVD in China 3IVD in China 4IVD in China 5IVD in China 6IVD in China 7IVD in China 8IVD in China 9IVD in China 10IVD in China 11IVD in China 12IVD in China 13Global Cardiovascular Implants Market 2015-2019 2
... BETHESDA, Md., July 05, 2007 /PRNewswire-FirstCall/ -- Micromet,Inc. ... of,novel, proprietary antibody-based products for cancer, inflammatory,and autoimmune ... Chief Executive Officer of Micromet, Inc., will,present at ... in New York on Thursday, July 12, 2007 ...
... WIRE)--Jul 2, 2007 - Tercica, Inc.,(NASDAQ:TRCA) today announced ... at the C.E. Unterberg, Towbin,Emerging Growth Opportunities Conference ... Wednesday, July 11, 2007 at 4:00 p.m. Eastern,time ... and slide presentation will be available,via the Internet ...
Cached Medicine Technology:Micromet, Inc. to Present at the 3rd Annual C.E. Unterberg, Towbin,Emerging Growth Conference 2
... Reviews enable all those involved with healthcare ... the very latest evidence in their field ... harder each year as the volume of ... by delivering the best single source available ...
Treatment Strategies in Cardiovascular Medicine...
Pocket Medicine's Cardiology Bundle includes the following 4 applications: Treatment Strategies in Cardiovascular Medicine, Treatment Strategies in Interventional Cardiology, Treatment Strategies in ...
The first book to translate key medical data into clear guidelines capturing the highest treatment standards for heart disease....
Medicine Products: