Navigation Links
JCI online early table of contents: Dec. 1, 2010
Date:12/1/2010

, Columbia University, New York, New York, USA.
Phone: 212.305.5565; Fax: 212.851.4540; E-mail: drb25@columbia.edu.

Hamid Reza Rezvani
INSERM U876, Bordeaux, F-33000 France.
Phone: 33.557.571.373; Fax: 33.556.983.348; E-mail: hamidreza.rezvani@u-bordeaux2.fr.

View this article at: http://www.jci.org/articles/view/40087?key=28190d52dba2e3e01752


HEMATOLOGY: A tale of unwanted blood clots

Antiphospholipid syndrome is a medical condition that causes blood clots to form within the arteries and veins, causing blockages that can damage tissues and organs. The blood clots are triggered by immune molecules known as antibodies. Specifically, antibodies that recognize proteins in the blood rather than invading microbes. Exactly how these antibodies trigger blood clot formation, is, however, not clear. But now, a team of researchers, led by Chieko Mineo, at the University of Texas Southwestern Medical Center, Dallas, has identified in mice a molecular pathway by which a subset of antibodies that cause antiphospholipid syndrome trigger blood clot formation. The team suggests that targeting this pathway might provide insight into new approaches for developing treatments for individuals with antiphospholipid syndrome.

TITLE: Antiphospholipid antibodies promote leukocyteendothelial cell adhesion and thrombosis in mice by antagonizing eNOS via beta-2GPI and apoER2

AUTHOR CONTACT:
Chieko Mineo
University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Phone: 214.648.2015; Fax: 214.648.2098; E-mail: Chieko.mineo@utsouthwestern.edu.

View this article at: http://www.jci.org/
'/>"/>

Contact: Karen Honey
press_releases@the-jci.org
734-546-5242
Journal of Clinical Investigation
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8 9 10

Related medicine news :

1. TheReliefPlace.com Launches Online Store “The Relief Shop” - What Does this Medical Supply Store Carry and How Can They Help You?
2. Web Content Management Enables Government Transparency, Participation, and Collaboration Online
3. DavisPTnetwork Partners with the New York Physical Therapy Association to Provide Online Continuing Education
4. PERSONALABS Offers Discounted Healthy Heart Online Blood Tests in February
5. Pharmahelper Pleased To Recognize Online Pharmacy Practice Standards Announced By Google Adwords
6. Online Dating Reinvents Itself with the Recent Roll-Out of Teacherhookup.com, a Free Website that Focuses on a Person's Career in Education!
7. EdenHome.com Adds Aventura Organic Clothes to Site and Announces Largest Online Selection of Stylish Organic Clothes for Men, Women and Children
8. Fire Protection Online Resolves Safety Concerns with CO2 Fire Extinguishers
9. JCI online early table of contents: Feb. 15, 2010
10. Fitness Trend Towards Online Personal Training Gets Real-World Weight Loss Results on FitOrbit.com
11. New Online Store Makes Buying Cosmetics a Healthy Choice
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... July 25, 2014 Newyorktermlifeinsurance.org has ... life insurance plans and traditional policies. , The ... clients make between no medical exam life insurance plans ... types of life insurance plans to provide a simple ... life insurance plans can now be purchased online. Although ...
(Date:7/25/2014)... July 25, 2014 CarePoint Health is ... Edward Boylan, has joined our network, CarePoint Health Medical ... Hundreds of highly skilled and experienced physicians comprise CarePoint ... and practices in Hudson County, representing a wide range ... to provide the highest quality care to patients and ...
(Date:7/25/2014)... Rockville Centre, NY (PRWEB) July 25, 2014 ... national personal injury law firm with over 25 ... of harm stemming from dangerous prescription drugs, announces ... , to offer information to those who believe ... Xarelto. , The site offers valuable information ...
(Date:7/25/2014)... TX (PRWEB) July 25, 2014 ... Outlook to 2020” provides company shares and distribution ... and global corporate-level profiles of the key market ... to the Laryngoscopes market wherever available. , The ... market forecast models. Rsearcher uses epidemiology and capital ...
(Date:7/25/2014)... Although cervical cancers are declining in the United States ... are increasing, a new study indicates. HPV-related cancers ... and tonsils have increased over the past 35 years, ... Canadian researchers report. "The increases in the incidence ... anal cancer among younger women are disturbing, because there ...
Breaking Medicine News(10 mins):Health News:No Medical Exam Life Insurance and Traditional Plans - Newyorktermlifeinsurance.org Provides Quotes for All Types of Life Insurance 2Health News:Dr. Boylan Joins CarePoint Health Medical Group 2Health News:Rottenstein Law Group LLP Announces Launch of Xarelto Injury Website 2Health News:Canada Cystoscopes, Laryngoscopes & Ureteroscopes Market Forecast to 2020 Reports Available at MarketOptimizer.org 2Health News:Canada Cystoscopes, Laryngoscopes & Ureteroscopes Market Forecast to 2020 Reports Available at MarketOptimizer.org 3Health News:Canada Cystoscopes, Laryngoscopes & Ureteroscopes Market Forecast to 2020 Reports Available at MarketOptimizer.org 4Health News:Canada Cystoscopes, Laryngoscopes & Ureteroscopes Market Forecast to 2020 Reports Available at MarketOptimizer.org 5Health News:Anal, Throat Cancers on the Rise Among Young Adults, Study Finds 2
... In a study of 14 adults with histories of ... not appear// to have effects that indicate potential for ... report in the October issue of Archives of General ... to 15 percent of adults regularly experience chronic insomnia, ...
... the time, they are nothing but a cosmetic nuisance. ... dividing abnormally to form a deadly form of skin ... this year will be diagnosed with melanoma at some ... percent of all melanomas begin in a mole. They ...
... of Nutrition in its current issue (October) has published ... Cookies TM can not only lower cholesterol levels but ... This would substantially curtail the risk of cardiac disease. ... purposes taken from the common fleawort, proven to be ...
... Health and Clinical Excellence (Nice) has planned new guidelines ... (porous bones) are at higher risk of fractures. The ... fragile bones. ,Post menopausal women at any ... wants to execute guidelines according to which, only women ...
... World Action on Salt and Health has been launched today ... 2.5 million deaths a year.// ,194 medical experts in ... companies into reducing dietary salt intake to prevent high blood ... a World Health Organisation summit in Paris to discuss the ...
... research proposes that the drug used to treat wet age-related ... vision in some people. // ,Wet AMD is the ... can be regained to some extent in people with a ... drug Lucentis. ,The study was published in the ...
Cached Medicine News:Health News:New Sleep Medication not Effective for Treating Abuse or Cognitive Impairment 2Health News:New Sleep Medication not Effective for Treating Abuse or Cognitive Impairment 3Health News:Why Don’t All Moles Progress to Melanoma 2Health News:Why Don’t All Moles Progress to Melanoma 3Health News:Chocolate Chip Cookies to Keep Cholesterol at Bay 2Health News:Food Makers Pressurized to Reduce Salt 2Health News:Vision restoration with a drug for macular degeneration 2
(Date:7/24/2014)... CITY, Calif. , July 24, 2014   ... specialty pharmaceutical company focused on the development and commercialization ... breakthrough pain, today confirmed the PDUFA date for Zalviso ... learned that a rumor circulated online stating the Food ... July 24, 2014 there has been no notification to ...
(Date:7/24/2014)... , and MARSEILLE, France , ... , Exclusive global license from University of Tokyo enables ... sequencing (NGS) gene panels, for blood cancers  ... test, indicate favorable prognosis for patients with bone marrow ... potential for developing companion diagnostics to guide treatment with ...
(Date:7/24/2014)... Amgen (NASDAQ: AMGN ) today announced ... Tuesday, July 29, 2014, after the close of the U.S. ... call with the investment community at 2 p.m. PT. Participating ... Bradway , chairman and chief executive officer, and other members ... the conference call will be simultaneously broadcast over the Internet ...
Breaking Medicine Technology:AcelRx Pharmaceuticals Confirms July 27, 2014 PDUFA Date for Zalviso 2QIAGEN Adds Promising Genomic Biomarkers for Assessing Prognosis in Treatment of Blood Cancers to Personalized Healthcare Pipeline 2QIAGEN Adds Promising Genomic Biomarkers for Assessing Prognosis in Treatment of Blood Cancers to Personalized Healthcare Pipeline 3QIAGEN Adds Promising Genomic Biomarkers for Assessing Prognosis in Treatment of Blood Cancers to Personalized Healthcare Pipeline 4QIAGEN Adds Promising Genomic Biomarkers for Assessing Prognosis in Treatment of Blood Cancers to Personalized Healthcare Pipeline 5Amgen Announces Webcast of 2014 Second Quarter Financial Results 2
The EK-H Series offer 10 selectable units of measure...
Digital Thermometer & High-Low Temp Alarm, -50C to +90C...
Thermometer for Round Water Bath...
... Digital Thermostat and Digital Display. , Exterior300 ... , Interiorwhite anodized aluminum with 300 ... refrigeration (134A). , Temperature range 0C ... doors. , Foamed-in-place polyurethane high density ...
Medicine Products: