Navigation Links
JCI online early table of contents: Dec. 1, 2010
Date:12/1/2010

be exploited to follow the progression of type 1 diabetes and to monitor the ability of different therapeutic agents to clear early stage disease.

TITLE: Noninvasive imaging of pancreatic islet inflammation in type 1A diabetes patients

Diane Mathis
Harvard Medical School, Boston, Massachusetts, USA.
Phone: 617.432.7742; Fax: 617.432.7744; E-mail: cbdm@hms.harvard.edu.

Ralph Weissleder
Massachusetts General Hospital, Boston, Massachusetts, USA.
Phone: 617.726.8226; Fax: 617.726.5708; E-mail: rweissleder@mgh.harvard.edu.

View this article at: http://www.jci.org/articles/view/44339?key=21b3be9f24b3689f8cf4


METABOLIC DISEASE: Warming up to brown fat

Fat is divided into two types: the white adipose (WAT), which stores energy, and the brown adipose (BAT), which burns energy to generate heat. WAT can be further divided into the layer under the skin (subcutaneous) and intra-abdominal (visceral) deposits. Excess visceral WAT is associated with increased risk of diseases such as diabetes and heart disease, but excess subcutaneous WAT is not. In addition, brown-like cells can appear within WAT during adaptation to cold and in response to anti-diabetic drugs. These cells are thought to increase heat production at the expense of energy storage, and mice with more brown-like cells are resistant to diet-induced obesity. Although the genes that control BAT and WAT generation have been described, it is not known what genes are required for "brown-like" cells to form.

In collaborative work from researchers at the University of Pennsylvania and the Dana-Farber Cancer Institute, Patrick Seale, Bruce Spiegelman, and colleagues investigated the molecular mechanisms that give rise to these brown-like cells. They found that
'/>"/>

Contact: Karen Honey
press_releases@the-jci.org
734-546-5242
Journal of Clinical Investigation
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8 9 10

Related medicine news :

1. TheReliefPlace.com Launches Online Store “The Relief Shop” - What Does this Medical Supply Store Carry and How Can They Help You?
2. Web Content Management Enables Government Transparency, Participation, and Collaboration Online
3. DavisPTnetwork Partners with the New York Physical Therapy Association to Provide Online Continuing Education
4. PERSONALABS Offers Discounted Healthy Heart Online Blood Tests in February
5. Pharmahelper Pleased To Recognize Online Pharmacy Practice Standards Announced By Google Adwords
6. Online Dating Reinvents Itself with the Recent Roll-Out of Teacherhookup.com, a Free Website that Focuses on a Person's Career in Education!
7. EdenHome.com Adds Aventura Organic Clothes to Site and Announces Largest Online Selection of Stylish Organic Clothes for Men, Women and Children
8. Fire Protection Online Resolves Safety Concerns with CO2 Fire Extinguishers
9. JCI online early table of contents: Feb. 15, 2010
10. Fitness Trend Towards Online Personal Training Gets Real-World Weight Loss Results on FitOrbit.com
11. New Online Store Makes Buying Cosmetics a Healthy Choice
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... York (PRWEB) January 22, 2015 The federal ... in the U.S. District Court, Southern District of West Virginia ... Inc. in that proceeding’s first bellwether trial. In an Order ... a new trial after finding that C.R. Bard had not ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 For over 20 years, ... Oceanside and Vista area has treated just about every ... personal injury circumstances. And for those same twenty-plus years, the ... of all those injuries with the best possible doctor. ...
(Date:1/22/2015)... Recently, Weddingshe.com has added many trendy Champagne wedding ... revenues in the past three years. Today, the business announces ... According to the sales manager of the company, this is ... 2015. This point can be reflected on the discounted wedding ...
(Date:1/22/2015)... New York, NY (PRWEB) January 22, 2015 ... component of overall health care gains momentum worldwide, Rev. ... York-based HealthCare Chaplaincy Network (HCCN), will be the ... advance spiritual care in Israel’s public health system. , The ...
(Date:1/22/2015)... January 22, 2015 State Forestry Institute ... management system with support from GEOSYSTEMS, a dedicated Hexagon ... solution will leverage Hexagon Geospatial’s ERDAS APOLLO ... as well as point clouds and documents. This effort ...
Breaking Medicine News(10 mins):Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 2Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 3Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 4Health News:Industry Leading Chiropractor in Oceanside Joins the Doctors on Liens Network 2Health News:Weddingshe Announces A Special Offer On Its Popular Glamorous Wedding Dresses 2Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 2Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 3Health News:State Forestry Institute Mecklenburg-Vorpommern, Germany Embraces Hexagon Geospatial Technology 2Health News:State Forestry Institute Mecklenburg-Vorpommern, Germany Embraces Hexagon Geospatial Technology 3
... chain of coffee cafes, on opening its 300th outlet in Mumbai ... of 500 by the year 2007. // ,"It ... have played a large role in firmly establishing the coffee café ... Bean Coffee Trading Company Ltd., the parent company of the chain. ...
... survey that found that almost 80 percent of Shanghai women ... ,Yu Junde, coordinator of Survey and head official of Shanghai ... wearing of bras which could affect their health. ... 18 to 50, which revealed that many were wearing very ...
... been documented in Acute Coronary Syndrome patients, instituted aggressive ... Society for Cardiovascular Angiography and Interventions (SCAI) // 29th ... ,By combining data from nine randomized clinical trials and ... analysis was able to put a sharper focus on ...
... have now identified a signaling pathway in the brain, ... food intake. Furthermore, this pathway linked to the development ... weight loss methods in obese individuals. ,Scientists ... pathway mTOR--activated by nutrient and hormonal signals--plays a role ...
... to the belief that adolescent boys tend to take romance ... it comes to heart matters, they might not be so ... is seen outside, an adolescent boy fails to communicate his ... mind. ,Boys are more vulnerable and emotionally engaged ...
... at the Gladstone Institute of Neurological Disease have now ... protein, apolipoprotein E, is indeed produced by neurons.// The ... established a definitive association between the two. ... common forms, one of which, apoE4, is the major ...
Cached Medicine News:Health News:Shanghai Women Don their Bras Improperly 2Health News:Statin Therapy in Patients with Acute Coronary Syndrome Improves Survival 2Health News:Study Highlights Appetite Regulation Pathway, New Hope for Weight Loss 2Health News:Teenage Boys More Vulnerable And Emotionally Engaged In Romantic Relationships 2Health News:Teenage Boys More Vulnerable And Emotionally Engaged In Romantic Relationships 3Health News:Alzheimer's-linked apolipoprotein E produced by neurons, Gladstone study 2
(Date:1/23/2015)... ANGELES , Jan. 23, 2015 A lot of ... best methods for treating  certain illnesses, injuries, or conditions. As ... replace previous treatment methods with ones that they consider to ... hernias, there is not one textbook method of treatment that ...
(Date:1/23/2015)... Jan. 23, 2015  The Partnership to Fight Chronic Disease (PFCD) released ... care leaders and a new study analyzing the impact of increased ... a nationwide coalition working to educate policy makers and the public ... Capitol was focused on how the Iowa ...
(Date:1/23/2015)... 2015  Northwest Biotherapeutics, Inc. (NASDAQ: NWBO )("NW Bio"), ... operable and inoperable solid tumor cancers, announced today that CEO ... Annual Phacilitate Immunotherapy Forum in Washington D.C. ... take place on January 26 at 10:30 a.m. EST at ...
Breaking Medicine Technology:No One-Size-Fits-All Remedy for Hernia Correction 2New research shows Iowa health exchange would benefit from improvements 2New research shows Iowa health exchange would benefit from improvements 3NW Bio To Present At The 7th Annual Phacilitate Immunotherapy Forum 2NW Bio To Present At The 7th Annual Phacilitate Immunotherapy Forum 3
... , , PHOENIX, ... published two new publications on hormone therapies and their effects on ... , Cardiovascular disease caused by atherosclerosis, or the build-up ... of American women--40% of total deaths--and the rate of mortality is ...
... OMER and MIGDAL HA,EMEK, Israel, August 3 ,Medigus ... visualization,medical devices, and Tower Semiconductor, Ltd. (Nasdaq: ... today announced successful,sampling of a new CMOS imager that ... its new medical devices camera; the smallest of its,kind ...
Cached Medicine Technology:TWO NEW KLRI PEER-REVIEWED PUBLICATIONS: Hormone Therapy May Reduce Atherosclerosis in Women Close to Menopause; Growth Hormone May Increase Risk of Diabetes, Improve Lipid Profile in Men 2TWO NEW KLRI PEER-REVIEWED PUBLICATIONS: Hormone Therapy May Reduce Atherosclerosis in Women Close to Menopause; Growth Hormone May Increase Risk of Diabetes, Improve Lipid Profile in Men 3Medigus and Tower Semiconductor Announce World's Smallest Medical Video Camera Based on Advanced CMOS Image Sensor 2Medigus and Tower Semiconductor Announce World's Smallest Medical Video Camera Based on Advanced CMOS Image Sensor 3Medigus and Tower Semiconductor Announce World's Smallest Medical Video Camera Based on Advanced CMOS Image Sensor 4
Intera 3.0T is the most compact high-field clinical whole-body MR system in the world, bringing 3.0T capabilities "out of the tunnel" and into the light of an open, patient-friendly design....
... are designed to provide distraction of ... disc removal, endplate preparation, and insertion ... of several Vertebral Spreaders, Intradiscal Wedges, ... Vertebral Body Positioner. Used in ALIF ...
... is a point-of-care system designed for the ... to as Platelet Rich Plasma - PRP) ... small sample of blood. The Symphony II ... which are found in the platelets. The ...
... gel has an extensive base of experience ... platelet gel. When concentrated autologous platelets are ... structural and functional changes involved in coagulation ... a number of factors including serotonin, fibronectin, ...
Medicine Products: