Navigation Links
JCI online early table of contents: April 11, 2011
Date:4/12/2011

uptake of the vaccine by dendritic cells. In addition, they found that conjugate vaccines induced the production of cytokines that contributed to the overall response. The authors believe that this work helps to define the responses to conjugate vaccines, and suggest new methods to enhance vaccine efficacy.

TITLE: Protective T cell immunity in mice following protein-TLR7/8 agonist-conjugate immunization requires aggregation, type I IFN, and multiple DC subsets

AUTHOR CONTACT:
Robert A. Seder
National Institutes of Health, Bethesda, MD, USA
Phone: 301-594-8483; Fax: ; E-mail: rseder@mail.nih.gov
View this article at: http://www.jci.org/articles/view/45416?key=a868e4ba1c1bb73bb26c


NEPHROLOGY Gene responsible for nephrotic syndrome and deafness identified

Nephrotic syndrome (NS) is a disorder that causes protein to leak from the blood into the urine, and a form of the disease that is resistant to treatment with steroids (SRNS) is frequent cause of end stage renal disease. SRNS has been linked to mutations in a few genes that are expressed in the podocyte cells of the kidney, but the genetic cause of the disease is unknown in the majority of cases, complicating the search for medical therapies. In new research, Friedhelm Hildebrandt and colleagues, of the Howard Hughes Medical Institute and the University of Michigan in Ann Arbor, performed genetic linkage studies to identify additional mutations that could cause SRNS. They found that in 13 patients, SRNS could be linked to mutations in the gene encoding COQ6, which is required for the synthesis CoQ10, an antioxidant enzyme with an additional role in the generation of cellular energy. Remarkably, treating these patients with CoQ10 improved renal function. Interestingly, the patients with COQ6 mutations also suffered from deafn
'/>"/>

Contact: Kathryn Claiborn
press_releases@the-jci.org
Journal of Clinical Investigation
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8

Related medicine news :

1. JCI online early table of contents: April 1, 2011
2. Digital Divide Opens Up in Patient Use of Online Medical Records
3. JCI online early table of contents: March 23, 2011
4. Online messaging delivers follow-up care for depression
5. JCI online early table of contents: March 14, 2011
6. JCI online early table of contents: March 7, 2011
7. Study Finds Drop in Online Sales of Cigarettes
8. JCI online early table of contents: Feb. 14, 2011
9. New online tool predicts probability of death from stroke
10. JCI online early table of contents: Feb. 7, 2011
11. Online registration opens for 14th World Conference on Lung Cancer in Amsterdam
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/1/2014)... 2014 Pastor Thompson is an ordained minister ... Village. He is a licensed minister through the Church of ... twenty years in New Mexico, Colorado and North Dakota. He ... this year. He also has two beautiful daughters, Brianna, ... Pastoral Ministry from Nazarene Bible College, in Colorado Springs and ...
(Date:9/1/2014)... Nevada (PRWEB) September 01, 2014 Beginning ... to over 3,000 medical professionals and 10,000 consumers for ... is a 5-day gathering of the nation’s top medical ... associated diseases or conditions. The week-long event contains more ... evidence-based scientific instruction available in the pain management field. ...
(Date:9/1/2014)... York, US (PRWEB) September 01, 2014 ... top-line view into Heartbeat Experts’ perspectives on ... Diabetes market. , Download the flash report ... strategies for any launching Diabetes product:, ... differentiation within an increasingly crowded market , ...
(Date:8/31/2014)... Washington, D.C.USA (PRWEB) August 31, 2014 ... the global community utilizing social media marketing tools ... and interactive programs. MMU will utilize all tools ... become learning partner for our multiple learning channels. ... new mobile app, and an authoring tool that ...
(Date:8/31/2014)... 2014 The FDA has recently proposed ... If adopted, the proposed changes would include more current ... sugars” on the label, and a new design. This ... sugars” off the label. NutriGold fully supports the new ... food choices. “After 20 years, it's time for a ...
Breaking Medicine News(10 mins):Health News:Medical Marijuana Doctor Company Set to Present at Las Vegas Pain Week 2Health News:Download HeartBeat Experts White Paper: Stakeholder Management for new Diabetes Products 2Health News:My Mobile University Announces Global Strategic Plan and Unveils New Android App to Enhance and Impact Lives World-Wide Through Education for All as Learning Platform 2Health News:My Mobile University Announces Global Strategic Plan and Unveils New Android App to Enhance and Impact Lives World-Wide Through Education for All as Learning Platform 3Health News:NutriGold Supports the FDA's Call for an Updated Nutrition Facts Label 2Health News:NutriGold Supports the FDA's Call for an Updated Nutrition Facts Label 3Health News:NutriGold Supports the FDA's Call for an Updated Nutrition Facts Label 4
... in place for hundreds of years. Using a novel technique, ... applying the procedure to Michelangelo,s David in an analysis that ... , In applying the technique to other objects -- including ... on how these structures are likely to fail. , On ...
... for people with dietary restrictions and personal ... ... has developed and created,its own software program that essentially reads the ... the,products available online and highlights the ones that meet customers,unique nutritional ...
... SAN DIEGO, March 18 The American Pharmacists,Association (APhA) ... for,an executive leadership transition. During the final session of ... John A. Gans, PharmD,Executive Vice-President and Chief Executive Officer ... Association will be coming to an end,in 2009, after ...
... Devices Will Protect Financial Privacy, WASHINGTON, ... community today commended 7-Eleven, Inc. for,installing tactile ... protect the,privacy and security of 7-Eleven shoppers ... keys arranged like a standard telephone keypad,and ...
... a world leader in stabilized rice bran (SRB), nutrient,research and ... role as Chief Financial Officer on March 31, 2008 and ... Financial Officer on that date.,Mr. Crow has agreed to stay ... responsibilities to Mr. Mueller., Mr. Mueller has over 20 ...
... IBM,s Dr. Richard Bakalar to Present Data Storage ... and Access Health Information, BOCA RATON, Fla., ... announced today that Dr. Richard Bakalar, chief medical,officer, ... webinar on Thursday,March 20, 2008 at 12:00 p.m. ...
Cached Medicine News:Health News:Tell them where it hurts 2Health News:Tell them where it hurts 3Health News:Peapod Offers First Ever Virtual Nutritionist 2Health News:APhA Announces Plans for Executive Leadership Transition 2Health News:7-Eleven, Inc.'s Upgrade of Point of Sale Equipment Praised by Blind Community 2Health News:7-Eleven, Inc.'s Upgrade of Point of Sale Equipment Praised by Blind Community 3Health News:NutraCea Appoints New Chief Financial Officer 2Health News:NutraCea Appoints New Chief Financial Officer 3Health News:Agilysys Hosts IBM Specialist at Health Care Webinar Offering Data Storage Solutions 2
(Date:8/29/2014)... 29, 2014  A Boston Scientific Corporation (NYSE: ... stent removability and preliminary long term stricture resolution ... the August issue of the peer-reviewed journal, Gastroenterology. ... is being conducted in 11 countries and five ... metal stents (FCSEMS) after extended indwell (i.e., up ...
(Date:8/29/2014)... , Aug. 29, 2014 Thoratec Corporation ... device-based mechanical circulatory support therapies to save, support and ... in the 2014 Morgan Stanley Global Healthcare Conference on ... , President and Chief Executive Officer, will provide an ... Daylight Time (9:55 a.m., Pacific Daylight Time).   ...
(Date:8/29/2014)... Aug. 29, 2014 Research and Markets ... Peptide Cancer Therapeutics Market & Pipeline Insight 2014" ... methods developed to prevent and eradicate the prevalence of ... methods are confined to low specificity, safety and large ... look for a better solution. It has been discovered ...
Breaking Medicine Technology:Boston Scientific Study Published In Gastroenterology Reports Successful Management Of Benign Biliary Strictures With Fully Covered Metal Stents 2Boston Scientific Study Published In Gastroenterology Reports Successful Management Of Benign Biliary Strictures With Fully Covered Metal Stents 3Boston Scientific Study Published In Gastroenterology Reports Successful Management Of Benign Biliary Strictures With Fully Covered Metal Stents 4Global Peptide Cancer Therapeutics Market & Pipeline Insight 2014 2
The Thermal pads were designed to simulate water immersion, the most effective method of transferring energy non-invasively....
The torso blanket is designed to affix to the lower abdominal area and cover the upper half of the body....
The torso blanket is designed to affix to the lower abdominal area and cover the upper half of the body....
Cocoon Disposable Patient Warming Blankets are specially designed to prevent hypothermia and maintain normothermia in your patients. The soft warm coloured material is strong and resists tearing and ...
Medicine Products: