Navigation Links
JCI early table of contents for Nov. 19, 2012
Date:11/19/2012

rchers at New York University to hypothesize that factors elicited by HIV-1 might block the function of DCs. In this issue of the Journal of Clinical Investigation, Bhardwaj and colleagues report that microparticles found in the plasma of HIV-1 patients inhibited the function of normal DCs and induced dendritic cell death. These results suggest that inhibition of these microparticles could promote DC activity and survival and help fight HIV-1.

TITLE:
HIV-1 infectioninduced apoptotic microparticles inhibit human DCs via CD44

AUTHOR CONTACT:
Nina Bhardwaj
NYU School of Medicine, New York, NY, USA
Phone: 1 212 263 5814; Fax: 2122636729; E-mail: nina.bhardwaj@nyumc.org

View this article at: http://www.jci.org/articles/view/64439?key=1d6cff10286e34fcfebf


B cells cross the blood-brain barrier in multiple sclerosis

In multiple sclerosis (MS), the blood-brain barrier (BBB) is compromised, allowing immune cells to attack the central nervous system (CNS). B cells are a population of immune cells that are thought to trigger autoimmune responses in MS, but it is unclear if they are able to transverse the BBB. In this issue of the Journal of Clinical Investigation, researchers led by Hans-Christian von Bdingen at the University of California, San Francisco, studied the ability of B cells to move between the peripheral blood and the CNS. By comparing the antibodies in the cerebrospinal fluid and the blood stream, von Bdingen and colleagues found populations of B cells that are common to both areas in patients with MS. This study demonstrates that B cells can cross the BBB and shows that they are central regulators of the pathological immune response in MS.

TITLE:
B cell exchange across the blood-brain barrier in multiple sclerosis

AUTHOR CONTACT:
'/>"/>

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation
Source:Eurekalert

Page: 1 2 3 4 5 6 7

Related medicine news :

1. Gene Distinguishes Early Birds from Night Owls and Helps Predict Time of Death
2. Early Menstruation Tied to Factors That Raise Heart Disease Risk
3. Early 50s may be key time to reach baby boomers with health messages
4. Early Exposure to Stress at Home Affects Girls Brains, Study Says
5. JCI early table of contents for Nov. 12, 2012
6. Predrinking Nearly Doubles Booze Consumption: Study
7. Early treatment sparks striking brain changes in autism
8. Imaging speeds early diagnosis of heart disease, the top killer in the Western world
9. JCI early table of contents for Nov. 1, 2012
10. Meth vaccine shows promising results in early tests
11. Radiation treatment after surgery improves survival for elderly women with early-stage breast cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2014)... 28, the Center for BrainHealth will bring together ... pressing brain-related challenges at its inaugural Brain Health ... Regeneration." Featured speakers will include Dr. Sandra Bond ... for BrainHealth, U.S. Senator Chuck Grassley (R-IA), U.S. ... Assistant Secretary for Policy and Early Learning, U.S. ...
(Date:4/24/2014)... one out of three survivors of critical illness, ... The Lancet Respiratory Medicine , and the majority ... mentally. , It is one of the largest ... outcomes of critical care survivors, according to lead ... and it highlights a significant public health issue, ...
(Date:4/24/2014)... The National Science Foundation has awarded LSU ... for Undergraduates (REU) Site grant in the amount ... of undergraduates from diverse social and educational backgrounds, ... Orleans area. The project will provide students ... of 2014-16. It will be led by ...
(Date:4/23/2014)... 24, 2014 Pregnant immigrants from Sub-Saharan Africa, ... monitoring during pregnancy, according to new research from ... in the British Journal of Obstetrics and ... eclampsia rates among immigrants and native-born women in ... Denmark, Sweden, Spain (Catalonia and Valencia) and the ...
(Date:4/23/2014)... Society for Radiation Oncology (ASTRO) has issued a ... for Endometrial Cancer: An ASTRO Evidence-Based Guideline," that ... the treatment of endometrial cancer. The guideline,s executive ... of Practical Radiation Oncology (PRO), the ... guideline is available as an open-access article online ...
Breaking Medicine News(10 mins):Health News:Inaugural Brain Health Summit focuses on brain resilience and regeneration 2Health News:Vanderbilt study finds physical signs of depression common among ICU survivors 2Health News:Vanderbilt study finds physical signs of depression common among ICU survivors 3Health News:Pregnancy complications may be more common in immigrants from certain regions 2Health News:ASTRO issues guideline on the role of postoperative radiation therapy for endometrial cancer 2Health News:ASTRO issues guideline on the role of postoperative radiation therapy for endometrial cancer 3
... the worldwide leader of post-breast surgery products, ... Collection, the industry,s first post-surgical garments infused ... discomfort after breast surgery.(Logo: ... http://www.newscom.com/cgi-bin/prnh/20090408/CL96087 )The post-surgical camisole and ...
... NORTH BRUNSWICK┬┐ N.J.┬┐ April 8 ORTHOCON┬┐ Inc. today ... company as President and Chief Executive Officer. The company ... of financing led by top-tier healthcare investors. ORTHOCON ... bone. The Company,s versatile technology platform may be leveraged ...
... for good nutrition but lack knowledge of food prep ... the current economic conditions, three-quarters of what people eat ... dependent on what food families keep in their kitchens. ... freezers, Rutgers University researchers found that, in ...
... Cordex Pharma, Inc. (OTC Bulletin Board: CDXP) announced today ... (BGM) in its Phase 2 clinical safety trial with ... BGM will measure levels of Galectin-3 in patients enrolled ... remodeling associated with advanced stages of heart failure. CDP-1050 ...
... NORTHFIELD, Ill., April 8 The College of American ... accreditation organization and deeming authority under the Clinical Laboratory ... and Medicaid Services (CMS) since 1995, has been notified ... subspecialties for a six-year period, the longest period available ...
... LAS VEGAS, April 8 Scheduled for June 5 ... garnered broad industry support and surpassed previous levels of ... this annual medical education and commercial exhibition event has ... a focal point for the high-growth medical aesthetic industry. ...
Cached Medicine News:Health News:Amoena Introduces First Post Surgical Garments With Vitamin E & Aloe to Help Soothe and Comfort After Breast Surgery 2Health News:ORTHOCON Announces Appointment of New CEO and $25 Million Series B Financing 2Health News:Rutgers Study Reveals A Need For Basic Kitchen Know-How 2Health News:Rutgers Study Reveals A Need For Basic Kitchen Know-How 3Health News:Cordex Pharma to Collaborate with BG Medicine in a Clinical Study of Heart Failure Biomarkers 2Health News:Cordex Pharma to Collaborate with BG Medicine in a Clinical Study of Heart Failure Biomarkers 3Health News:Cordex Pharma to Collaborate with BG Medicine in a Clinical Study of Heart Failure Biomarkers 4Health News:CAP Deeming Status Renewed 2Health News:THE Aesthetic Show Attracts Record Sponsorship 2Health News:THE Aesthetic Show Attracts Record Sponsorship 3
(Date:1/15/2014)... IRVING, Texas , Jan. 15, 2014  Novation, the ... company, awarded several new IT value-added reseller (VAR) national ... with IT goods and services at lower costs. These ... value-added services such as initiative assistance and ongoing IT ...
(Date:1/15/2014)... , Jan. 15, 2014 Massachusetts General Hospital ... AMGN ) announced today that they have ... validate new therapeutic targets and develop novel therapies ... that affects millions worldwide. The MGH-Broad-Amgen collaboration brings ...
(Date:1/15/2014)... FORT WORTH, Texas , Jan. 15, 2014  Humberto ... in Dermatology Achievement Award" from the Journal of ... Dermatology Aesthetic & Clinical Conference (ODAC). The event is January ... Florida . The ...
Breaking Medicine Technology:New Novation Information Technology VAR Contracts Offer Significant Savings to Hospitals 2Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 2Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 3Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 4Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 2Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 3Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 4
... MicroDose Technologies,Inc. (MicroDose) today announced that the first ... Inc., through a Merck affiliate, has been,achieved, triggering ... MicroDose,s dry powder inhaler (DPI) technology announced in ... of a Phase I clinical,study of an investigational ...
... -Trial to Examine New Therapeutic Platform in Patients with Cystoid Macular ... ... SUNNYVALE, Calif., Aug. 5 Icon Bioscience, Inc., (IBI),a privately ... its Phase I clinical trial to assess the,safety and efficacy of ...
Cached Medicine Technology:MicroDose Technologies Announces Achievement of Phase I Clinical Milestone Triggering First Milestone Payment Under Collaboration with Merck & Co., Inc. 2Icon Bioscience Completes Enrollment in Phase I Study of Novel Ophthalmic Drug Candidate 2
Sabre 180 is a powerful niche generator....
The Sabre 2400 provides high power performance and key user features to meet today's demanding electrosurgical needs. It is an ideal general-purpose electrosurgical generator....
The Sabre 2400 provides high power performance and key user features to meet today's demanding electrosurgical needs. It is an ideal general-purpose electrosurgical generator....
The ExcaliburPlus PC is the most powerful isolated ESU with 10,000 V PTP in spray coag....
Medicine Products: