Navigation Links
JCI early table of contents for Nov. 12, 2012
Date:11/12/2012

Home field advantage: Intravaginal immunization may help protect against infection

Sexually-transmitted diseases (STDs) enter the body through the mucosal epithelial cells and the ability to direct pathogen-clearing T-cells to points of infection may be the critical element in developing successful vaccines against these infections. In a study published in the Journal of Clinical Investigation, researchers led by John Schiller at the National Cancer Institute investigated the immune response to intravaginal immunization in mice infected with a form of the HPV virus carrying a model antigen. They found that intravaginal immunization significantly increased the number of immune cells present in the vaginal mucosa compared with a general immune system booster. These results indicate that site-specific vaccination enhances the local immune system response and may be useful in developing STD vaccines.

TITLE:
Intravaginal immunization with HPV vectors induces tissue-resident CD8+ T cells

AUTHOR CONTACT:
John Schiller
National Cancer Institute, Bethesda, MD, USA
Phone: 301-594-2715; Fax: 301-480-5322; E-mail: schillej@dc37a.nci.nih.gov

View this article at: http://www.jci.org/articles/view/63287?key=95b0c2a37738d68fcd61


HIV-1 vaccine development: pinning down a moving target

HIV-1 is a genetically diverse collection of viruses, making it a moving target in vaccine development. In a study published in the Journal of Clinical Investigation, researchers led by Brad Jones at the University of Toronto in investigated the feasibility of eliminating HIV-infected cells by targeting cellular immune responses against a human endogenous retrovirus (HERV). HERVs are the DNA remnants of ancient infectious retroviruses that became part of the germ line cell
'/>"/>

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation
Source:Eurekalert

Page: 1 2 3 4 5 6 7

Related medicine news :

1. Predrinking Nearly Doubles Booze Consumption: Study
2. Early treatment sparks striking brain changes in autism
3. Imaging speeds early diagnosis of heart disease, the top killer in the Western world
4. JCI early table of contents for Nov. 1, 2012
5. Meth vaccine shows promising results in early tests
6. Radiation treatment after surgery improves survival for elderly women with early-stage breast cancer
7. ESDM early intervention improves brain activity associated with social cues
8. Mayo Clinic researchers develop new tools to better treat ADHD patients in early stages
9. Short-Term, Early HRT May Cut Womens Alzheimers Risk: Study
10. Simple ovarian cancer symptom survey that checks for 6 warning signs may improve early detection
11. Nearly half of kidney recipients in live donor transplant chains are minorities
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... On October 22, CBS will air ... diseases both fictional and real. The Charles E ... committed to advocacy and philanthropy in the battle against ... opportunity to impart truth and clarity about this misunderstood ... many misconceptions about Morgellons Disease (MD) and ...
(Date:10/22/2014)... Amy Norton HealthDay Reporter ... remain riveted on the three Ebola cases in Dallas. But, ... health threat to Americans. President Barack Obama on Friday ... the virus, which has infected two Dallas nurses who cared ... at Texas Health Presbyterian Hospital. But the U.S. cases ...
(Date:10/22/2014)... 22, 2014 Hay House is pleased to ... and Upgrade Your Life (Paperback; $10.82) written by the highly ... Recovery. This book is meant to help readers of ... of recovery. , Recovery 2.0 is not the average ... 2.0 is a guide for what comes next. ...
(Date:10/22/2014)... 2014 Healthcare professionals who are ... education at home or on-the-go via laptops, tablets ... brand new, premium Seminar-on-Demand CE courses. The new ... 2,000 hours of CE course offerings, ... experience. With such a diverse library, there’s something ...
(Date:10/22/2014)... (PRWEB) October 22, 2014 Richard Carlson, ... an industry leader with over 25 years experience. ... leader in the areas related to EDI, B2B Commerce, ... is an Editorial Advisory Board member for Pharmaceutical Commerce ... Blue Fin Group is a management and technology ...
Breaking Medicine News(10 mins):Health News:CBS’ Criminal Minds takes aim at skin disease with Morgellons in the Mix 2Health News:CBS’ Criminal Minds takes aim at skin disease with Morgellons in the Mix 3Health News:Ebola Anxiety: A Bigger Threat Now Than the Virus Itself 2Health News:Ebola Anxiety: A Bigger Threat Now Than the Virus Itself 3Health News:Hay House Announces The Official Release of Recovery 2.0: Move Beyond Addiction and Upgrade Your Life 2Health News:Hay House Announces The Official Release of Recovery 2.0: Move Beyond Addiction and Upgrade Your Life 3Health News:Top Provider of Continuing Education at Home Releases 20 New Online Courses 2Health News:Rich Carlson and Marc Duey to Hold Workshop at CBI’s Specialty Pharmacy and Distribution Networks Conference 2
... , SCOTTSDALE, Ariz., Nov. 12 Healthcare Trust of ... investment trust, announced the execution of a Purchase and ... building located in Spartanburg, South Carolina for approximately $16,250,000. ... number of conditions. , The approximate 108,500 SF Mary ...
... MONTREAL, Nov. 12 The International Peak Performance Symposium ... - Via Scarlatti, 33 (close to Stazione Centrale), Milan ... , The conference will focus on the benefits that ... Peak Performance both in Sports and Business. Modern approaches ...
... found elevated amounts of protein involved in blood-brain barrier ... have a biological effect on the brain, but it,s ... risks, a Swedish medical researcher reports. , Fredrik Soderqvist, ... phone users and discovered they had elevated levels of ...
... that lead to myotonic dystrophy , THURSDAY, Nov. 12 (HealthDay ... pneumonia might serve as an effective treatment against a type ... mice and found that it appears to combat genetic defects ... types of muscular dystrophy. The muscle-wasting condition is also known ...
... Rats fed sugary chow suffered withdrawal when regular meals returned , ... of dieting? Join the club. But new research in rats hints ... as kicking drug addiction. , In the study, rats weaned off ... withdrawing from drugs and alcohol. , Rat brains aren,t the same ...
... ... facility in Lake Success, NY. The facility will house some of the practice’s ... M.D., Neuro-Ophthalmologist Scott Uretsky, M.D., Neuropsychologist Gad E. Klein, Ph.D. and Neurophysiologist Marat ... needs of pediatric patients. , ...
Cached Medicine News:Health News:Healthcare Trust of America, Inc. Executes Agreement to Acquire a 108,500 SF Medical Office Building Located in Spartanburg, South Carolina 2Health News:Peak Performance, Neurofeedback and Biofeedback: New Frontiers of Empowerment From, and In, Sport 2Health News:Wireless Phones Alter Levels of Brain Chemical 2Health News:Study Links Yo-Yo Dieting to Addiction 2Health News:Study Links Yo-Yo Dieting to Addiction 3Health News:Neurological Surgery, P.C., of Long Island, NY, Adds New Specialists and Opens New Flagship Facility in Lake Success, NY 2Health News:Neurological Surgery, P.C., of Long Island, NY, Adds New Specialists and Opens New Flagship Facility in Lake Success, NY 3
(Date:10/22/2014)... BASKING RIDGE, N.J. , Oct. 22, 2014 ... (RMANJ), a world-renowned leader in the field ... more rapid approach to embryonic screening. The research ... American Society for Reproductive Medicine (ASRM) meeting in ... chromosome screening (CCS) and single gene defect (SGD) ...
(Date:10/22/2014)... AVACEN Medical announced today that its AVACEN ... clearance by the U.S. Food and Drug Administration. This ... the Internet for: the temporary relief of joint ... and sprains . Logo - http://photos.prnewswire.com/prnh/20141021/153513 ... is a sophisticated medical device incorporating over 3,000 firmware ...
(Date:10/22/2014)... YARDLEY, Pa. , Oct. 22, 2014 /PRNewswire/ ... of their animal health medications, a Global Pharmaceutical ... and Antares serialization technology and turnkey solution to ... Photo - http://photos.prnewswire.com/prnh/20141021/153438 ... The product that was serialized and aggregated by ...
Breaking Medicine Technology:New IVF Research Highlights Improved Genetic Screening Approach To Help Parents Have Healthier Babies 2New IVF Research Highlights Improved Genetic Screening Approach To Help Parents Have Healthier Babies 3AVACEN Medical Announces FDA Clearance of First Medical Device with Internal Game Mode 2Xyntek and Antares Serialization Solution Protects Pets Too! 2
... Mesa Laboratories, Inc. (Nasdaq: MLAB ) today announced that ... of the Company,s Board of Directors, effectively immediately. , ... "Paul,s experience and insight have been extremely helpful ... J. Sullivan , President and CEO.  "Paul managed Mesa,s Medical product line ...
... July 8 Roxane Laboratories, Inc. announced today the approval ... by the U.S. Food and Drug Administration.  The product is available ... nationwide. , , , ... Laboratories, Anastrozole Tablets are AB rated to ARIMIDEX® (anastrozole) tablets.  Annual ...
Cached Medicine Technology:Paul D. Duke Resigns From Mesa's Board of Directors 2Roxane Laboratories, Inc. Announces the Launch of Anastrozole Tablets 2Roxane Laboratories, Inc. Announces the Launch of Anastrozole Tablets 3
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: