Navigation Links
JCI early table of contents for June 24, 2013
Date:6/24/2013

ith all three types of dendritic cells elicited an immune response, which peaked after 3-4 vaccinations with dendritic cells. Patients that received the specially modified dendritic cells had a longer lasting immune response and fewer circulating melanoma cells. Of the two patients that had active disease, treatment with modified dendritic cells resulted in a partial clinical response in one and a complete clinical response in the other. These results suggest that modification of dendritic cells so that they recognize cP-produced tumor antigens enhances immune recognition of melanoma cells.

This study was funded by Duke Clinical Research Institute/Duke Translational Medicine Institute, Duke Melanoma Consortium, and Duke University Department of Surgery. Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, etc.

TITLE: Melanoma immunotherapy using mature DCs expressing the constitutive proteasome

AUTHOR CONTACT: Scott Pruitt
Merck Research Laboratories, Rahway, NJ, USA
Phone: 919-632-6118; Fax: 732-594-5512; E-mail: scott.pruitt@merck.com

View this article at: http://www.jci.org/articles/view/67544?key=ca11555dad2fe390851f


Researchers identify a protein that hinders the immune response to severe bacterial infections

Clearance of invading pathogens is essential to prevent overwhelming inflammation and sepsis that are symptomatic of bacterial peritonitis, an infection of the abdominal cavity. Macrophages are immune cells that participate in the immune response by engulfing and digesting pathogens, a process called phagocytosis. Oxidized phospholipids (OxPL) are molecules generated in response to infection that can prevent bacterial clearance by phagocytosis. In this i
'/>"/>

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8 9

Related medicine news :

1. New Stool Test Might Aid in Early Detection of Colon Cancer
2. An Early Start for Your Child with Autism
3. Early Study Finds Some Promise for Lung Cancer Vaccine
4. Treat Rheumatoid Arthritis Early and Aggressively: Guidelines
5. JCI early table of contents for April 9, 2012
6. Eye Tremors May Aid Early Diagnosis of Parkinsons: Study
7. Nearly 1 in 4 grandparents store prescription medicines where children can easily find them
8. First contact: Early intervention key in diagnosis and treatment of serious mental illness
9. Brain Tumor Vaccine Shows Promise in Early Trial
10. Role of Screening, Monitoring in Early Kidney Disease Unclear
11. Detecting malaria early to save lives: New optical technique promises rapid and accurate diagnosis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/5/2015)... Central Nebraska Imaging (CNI) is pleased to ... new logo and optimized website. , CNI’s ... to expert diagnostic imaging, centered on patient care. The ... be a resource for Nebraska patients and a tool ... and referral functionality, video content and resources to understand ...
(Date:3/5/2015)... March 05, 2015 HomeCEUConnection.com ... March with extra savings on their nutrition ... of health and nutrition, HomeCEUConnection.com is offering ... the promo code, NUTRITION2015 . , ... , HomeCEUConnection.com provides high-quality continuing education ...
(Date:3/5/2015)... On March 2, 2015, NBC News posted ... Rise, Plastic Surgeons Say,” that comments on the 2014 ... Plastic Surgery and the American Society of ... doubling of surgical butt augmentations performed in 2014. According ... this increase can be attributed to the social impact ...
(Date:3/5/2015)... In honor of National Drug Facts Week, ... and alcohol abuse in schools and communities across America, ... information on some of the dangers and statistics involved ... Institute on Drug Abuse, this annual promotion of the ... illusions that teens and young adults get from television, ...
(Date:3/5/2015)... MS (PRWEB) March 05, 2015 At ... Basics and Beyond,” leaders in addiction treatment met today ... updates in best clinical practices. Among the numerous respected ... , who will address the role that pain medications ... and new evidence-based treatment options. , "It is hard ...
Breaking Medicine News(10 mins):Health News:Central Nebraska Imaging Center Gets Rebranding 2Health News:HomeCEUConnection.com Offers Nutrition CEUs this March to Celebrate Nutrition Month 2Health News:The Kim Kardashian and Jennifer Lopez Effect: Butt Augmentations Double from 2013 to 2014 2Health News:A Forever Recovery Issues New Tips for Sobriety for National Drug Facts Week 2Health News:National Addiction Treatment Expert William S. “Bill” Jacobs, Md Speaks At Prestigious 7th Annual Mississippi Addiction Conference 2Health News:National Addiction Treatment Expert William S. “Bill” Jacobs, Md Speaks At Prestigious 7th Annual Mississippi Addiction Conference 3
... can learn much from each other in regard ... wrong-site surgeries, HARRISBURG, Pa., Jan. 10 ... decreased during 2007, some,facilities continue to report wrong-site ... protocols implemented by other Pennsylvania,facilities that have been ...
... Prepares to Release Alarming New HIV Rates; Governor ... 10 AIDS Healthcare,Foundation (AHF) today urged California ... of proposed budget cuts in AIDS services,that will ... for,Californians living with HIV/AIDS as he seeks to ...
... for "The Grove Circle," Honoring Planned Gift Donors,Reflects Shared ... - Andrew S. Grove,co-founder of technology giant Intel and ... Research, announced his intent to bequeath a,portion of his ... Fox Foundation.,Mr. Grove,s gift will establish The Grove Circle, ...
... can alter timetable , , THURSDAY, Jan. 10 (HealthDay News) -- ... a half years following their diagnosis, new British research shows. ... life expectancy, according to the report in the Jan. 11 ... Common socioeconomic influences, such as marital status, social class and ...
... January 9, 2008 In a study published ... from the University of Aberdeen report that the ... and praised as "the first and,only representative of ... fact similar,to other existing compounds, and is beneficial ...
... Animal study shows preconditioning cardiac cells helps organ better tolerate ... -- Just as daily runs can prepare you to survive ... spells could condition cardiac cells to better withstand the damage ... University of Cincinnati suggests. , Ultimately, if validated in humans, ...
Cached Medicine News:Health News:Patient Safety Authority Visits Facilities for Information on Wrong-Site Surgery 2Health News:Patient Safety Authority Visits Facilities for Information on Wrong-Site Surgery 3Health News:Patient Safety Authority Visits Facilities for Information on Wrong-Site Surgery 4Health News:AHF to Schwarzenegger: 'AIDS Cuts Are Deadly' 2Health News:AHF to Schwarzenegger: 'AIDS Cuts Are Deadly' 3Health News:Intel Co-Founder Andrew S. Grove Dedicates Portion of His Estate, Up to $40 Million, to Michael J. Fox Foundation 2Health News:Intel Co-Founder Andrew S. Grove Dedicates Portion of His Estate, Up to $40 Million, to Michael J. Fox Foundation 3Health News:Dementia Diagnosis Typically Means Death Within Five Years 2Health News:Memantine and Alzheimer's disease 2Health News:Memantine and Alzheimer's disease 3Health News:Priming Heart Before an Attack Could Limit Damage 2Health News:Priming Heart Before an Attack Could Limit Damage 3
(Date:3/5/2015)... March 5, 2015 Vermillion, Inc. (Nasdaq: ... focused on gynecologic disease, announced today it will ... the market open on Wednesday, March 25, 2015, ... at 8:30am Eastern. Conference Call & Webcast: ... Eastern/5:30am Pacific Domestic: , 800-753-9057International: , 913-981-5571Conference ID: ...
(Date:3/5/2015)... YORK , March 5, 2015  As ... set of regulations, Ethics & Compliance professionals are ... to a new survey issued today by LRN, ... and education. An overwhelming majority of respondents expressed ... the most important component of E&C training programs ...
(Date:3/5/2015)... -- Sanomedics, Inc. (OTC: SIMH, SIMHD) ("Sanomedics" or the "Company"), ... and acquiring cutting-edge technology, products and services announced today ... at booth # 709 at the National Association ... on March 11-13, 2015 at Caesars Palace in ... The 36 th annual NAPNAP Conference will bring ...
Breaking Medicine Technology:Vermillion to Report Fourth Quarter and Year-End 2014 Financial Results and Host an Investor Conference Call on March 25 2Pharmaceutical Ethics & Compliance Professionals Place Company Values Front and Center 2Pharmaceutical Ethics & Compliance Professionals Place Company Values Front and Center 3Sanomedics to Showcase the Caregiver at National Association of Pediatric Nurse Practitioners Conference 2Sanomedics to Showcase the Caregiver at National Association of Pediatric Nurse Practitioners Conference 3
... Cytotech Labs, a Boston based pharmaceutical company and ... Berg Biosystems and Berg Diagnostics today presented groundbreaking insight ... Otto Warburg.  The Warburg Hypothesis asserts that increased utilization ... by cancer cells in return for evasion of apoptosis, ...
... April 4, 2011 Breckenridge is announcing that it entered ... Salalah, Sultanate of Oman to market Neomycin Sulfate Tablets. Under ... by Oman Pharma, and marketed and distributed by Breckenridge on ... been approved by the U.S. Food and Drug Administration (FDA), ...
Cached Medicine Technology:Cytotech Labs Unravels Hallmark Insight Into Metabolic Control of Cancer, Presents Work at Major AACR Cancer Meeting 2Cytotech Labs Unravels Hallmark Insight Into Metabolic Control of Cancer, Presents Work at Major AACR Cancer Meeting 3Cytotech Labs Unravels Hallmark Insight Into Metabolic Control of Cancer, Presents Work at Major AACR Cancer Meeting 4
Blunt tlpped forceps wlth smooth jaws that have been diamond dusted for enhanced grasping. Excellent for grasping of immature membranes....
Blunt tipped forceps with entire interior surface of tip serrated. For general purpose membrane grasping (coarse membranes)....
Pic forceps design that is slightly curved; tips have special "surface treatment" for enhanced manipulation of the retina....
Blunt tipped forceps with very small grasping platforms on each tip. For grasping very fine membranes or grasping membranes adherent to the retinal surface....
Medicine Products: