Navigation Links
JCI early table of contents for June 24, 2013
Date:6/24/2013

RESEARCH BRANCH, NICHD, NIH, DHHS, Detroit, MI, USA
Phone: 313-993-2700; Fax: 313-993-2694; E-mail: romeror@mail.nih.gov

View this article at: http://www.jci.org/articles/view/70431?key=a945472a049b383326f4


The inflammatory consequences of chronic cannabis use

Chronic cannabis use has been associated with defects in the regions of the brain that regulate motor control, but how the active component of the drug, THC, mediates these defects is incompletely understood. In this issue of the Journal of Clinical Investigation, Andres Ozaita and colleagues at Universitat Pompeu Fabra in Barcelona exposed mice to sub-chronic doses of THC and observed deficiencies in learning and coordination associated with brain inflammation and downregulation of the THC receptor CB1R. Furthermore, Ozaita and colleagues found that the defects in these animals could be prevented by treatment with an anti-inflammatory agent. This work suggests that brain inflammation resulting from decreased CB1R is directly related to the learning and motor coordination side effects associated with cannabis consumption. In the accompanying commentary, Nephi Stella at the Center for Human Development and Disability in Seattle points out that these findings raise questions about the safety of medicinal THC applications.

TITLE: Mechanisms underlying the cerebellar deficits produced by repeated cannabis exposure

AUTHOR CONTACT: Andres Ozaita
Universitat Pompeu Fabra, Barcelona, ESP
Phone: +34 933160823; E-mail: andres.ozaita@upf.edu

View this article at: http://www.jci.org/articles/view/67569?key=f8f84f1e2997cbac8aad

ACCOMPANYING COMMENT
'/>"/>

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8 9

Related medicine news :

1. New Stool Test Might Aid in Early Detection of Colon Cancer
2. An Early Start for Your Child with Autism
3. Early Study Finds Some Promise for Lung Cancer Vaccine
4. Treat Rheumatoid Arthritis Early and Aggressively: Guidelines
5. JCI early table of contents for April 9, 2012
6. Eye Tremors May Aid Early Diagnosis of Parkinsons: Study
7. Nearly 1 in 4 grandparents store prescription medicines where children can easily find them
8. First contact: Early intervention key in diagnosis and treatment of serious mental illness
9. Brain Tumor Vaccine Shows Promise in Early Trial
10. Role of Screening, Monitoring in Early Kidney Disease Unclear
11. Detecting malaria early to save lives: New optical technique promises rapid and accurate diagnosis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/3/2015)... , ... September 03, 2015 , ... At Renew Man™, ... dissatisfied with the traditional health care model, where the primary care physician dictates and ... who want to become educated about their health issues and empowered to choose their ...
(Date:9/3/2015)... ... September 03, 2015 , ... ... Bob Anders and Kelley Chapman will be joining the company’s executive leadership team ... Anders has over 30 years’ experience in healthcare product and project management. He ...
(Date:9/2/2015)... ... September 03, 2015 , ... Leah ... among the most influential leaders in healthcare, will offer the keynote address at ... place October 15-16, 2015, in Palm Harbor, Florida, at the Innisbrook Resort and ...
(Date:9/2/2015)... ... ... Chris Harrison of Harrison’s Footwear of Poulsbo announces the launch of his ... “We have a lot of repeat customers, and many of them drive quite a ... given them the convenience of ordering from home.” , Harrison’s Footwear has gained a ...
(Date:9/2/2015)... (PRWEB) , ... September 02, 2015 , ... Telehealth represents ... Well Corp., contracted to handle the telehealth services of more than 12 Blues plan ... and Blue Shield Plans takes a look this growing trend, interviewing executives at Capital ...
Breaking Medicine News(10 mins):Health News:Men Dissatisfied with the Primary Care Physician’s Approach to Andropause Are Turning to Renew Man™ 2Health News:Men Dissatisfied with the Primary Care Physician’s Approach to Andropause Are Turning to Renew Man™ 3Health News:Leading Post-Acute EMR Provider HealthWyse Names Bob Anders as VP Product and Kelley Chapman VP Engineering 2Health News:Leading Post-Acute EMR Provider HealthWyse Names Bob Anders as VP Product and Kelley Chapman VP Engineering 3Health News:ACO Coalition Meeting to Feature Leapfrog’s Leah Binder 2Health News:ACO Coalition Meeting to Feature Leapfrog’s Leah Binder 3Health News:Harrison's Comfort Footwear Announces Expansion with New CHarrison Online Store 2Health News:AIS Newsletter Focuses on Growing Telehealth Trend Among Blues Plans 2Health News:AIS Newsletter Focuses on Growing Telehealth Trend Among Blues Plans 3
... Corporation (NYSE: BSX ) today announced financial results for the ... sales and earnings per share (EPS) for the second quarter and full ... are constant currency): , , ... $0.19, both in line with guidance (GAAP loss per share of $0.01) ...
... NEWTOWN, Pa., April 20 The managing director ... been invited to speak at the 45th Annual ... W. Singer will be present a talk entitled ... June 23, 2009.DIA is a pharmaceutical industry five-day ...
... the only reason lizards and other cold-blooded critters bask ... the May/June issue of Physiological and Biochemical Zoology ... need for vitamin D. , "It,s a longstanding assumption ... says Kristopher Karsten, a biologist at Texas Christian University ...
... Innovations, Inc. (Nasdaq: YDNT ) today announced that it ... on-demand web cast conference call on Tuesday, April 28, 2009 at ... call will be available through InterCall at http://tinyurl.com/ydnt1QTR09 ... will also be available through the Company,s website, www.ydnt.com ...
... 20 Insulet Corporation (Nasdaq: PODD ), ... OmniPod(R) Insulin Management System, announced plans to release its ... May 7, 2009 after the close of the financial ... p.m. Eastern Time on Thursday, May 7, 2009 to ...
... needed economic boost to primary care services for Floridians ... Speaker Nancy Pelosi joined Rep. Debbie Wasserman Schultz today ... discuss the positive impact of the American Recovery and ... $10 million in federal stimulus money to fund eight ...
Cached Medicine News:Health News:Boston Scientific Announces Results For First Quarter Ended March 31, 2009 2Health News:Boston Scientific Announces Results For First Quarter Ended March 31, 2009 3Health News:Boston Scientific Announces Results For First Quarter Ended March 31, 2009 4Health News:Boston Scientific Announces Results For First Quarter Ended March 31, 2009 5Health News:Boston Scientific Announces Results For First Quarter Ended March 31, 2009 6Health News:Boston Scientific Announces Results For First Quarter Ended March 31, 2009 7Health News:Boston Scientific Announces Results For First Quarter Ended March 31, 2009 8Health News:Boston Scientific Announces Results For First Quarter Ended March 31, 2009 9Health News:Boston Scientific Announces Results For First Quarter Ended March 31, 2009 10Health News:Boston Scientific Announces Results For First Quarter Ended March 31, 2009 11Health News:Boston Scientific Announces Results For First Quarter Ended March 31, 2009 12Health News:Boston Scientific Announces Results For First Quarter Ended March 31, 2009 13Health News:Boston Scientific Announces Results For First Quarter Ended March 31, 2009 14Health News:Boston Scientific Announces Results For First Quarter Ended March 31, 2009 15Health News:Boston Scientific Announces Results For First Quarter Ended March 31, 2009 16Health News:Boston Scientific Announces Results For First Quarter Ended March 31, 2009 17Health News:Boston Scientific Announces Results For First Quarter Ended March 31, 2009 18Health News:Boston Scientific Announces Results For First Quarter Ended March 31, 2009 19Health News:Boston Scientific Announces Results For First Quarter Ended March 31, 2009 20Health News:Boston Scientific Announces Results For First Quarter Ended March 31, 2009 21Health News:Study: Lizards bask for more than warmth 2Health News:Young Innovations, Inc. Provides First Quarter Conference Call Details 2Health News:Insulet Corporation to Report First Quarter 2009 Financial Results on Thursday, May 7, 2009 2Health News:Speaker Pelosi Visits Florida Health Center 2
(Date:9/2/2015)... YORK , Sept. 2, 2015 About ... is a malignant condition characterized by increased production of ... affects B-lymphocytes and then it can spread to other ... at later stages because of the slow buildup of ... the malignancy spreads to the spleen, liver, and lymph ...
(Date:9/2/2015)... Sept. 2, 2015 Research and Markets ( http://www.researchandmarkets.com/research/l8z67c/pharmaceutical ... Affairs in China (Basel, Switzerland - November 26-27, 2015)" ... provide a detailed overview of the key areas of pharmaceutical ... Hong Kong , Macau and ... - All important aspects of gaining and maintaining a ...
(Date:9/2/2015)... Miss. , Sept. 2, 2015   Gulf Coast Tattoo ... removal services with the cutting-edge Astanza Duality laser in ... unwanted ink erase their tattoo regret and take back control of ... but extends its services to Biloxi ... region. "With tattoo regret being as prevalent as it ...
Breaking Medicine Technology:Global Chronic Lymphocytic Leukemia Therapeutics Market 2015-2019 2Global Chronic Lymphocytic Leukemia Therapeutics Market 2015-2019 3Pharmaceutical Regulatory Affairs in China Seminar: Basel, Switzerland - November 26-27, 2015 2Gulf Coast Tattoo Removal Delivers Unrivaled Tattoo Removal Results To Biloxi And Gulfport With Astanza Duality 2
... ALTO, Calif., April 25, 2012  Varian Medical Systems (NYSE: ... quarter of fiscal year 2012 with net earnings of $0.94 ... share in the second quarter of fiscal year 2011.  The ... a $2.5 million or $0.02 per diluted share restructuring charge ...
... AKRON, Ohio, April 25, 2012  Researchers, health care ... for the inaugural National Conference on Value-driven Engineering ... assembled by the Austen BioInnovation Institute in Akron ... Foundation. Experts from some of the nation,s leading ...
Cached Medicine Technology:Varian Medical Systems Reports Results for Second Quarter of Fiscal Year 2012 2Varian Medical Systems Reports Results for Second Quarter of Fiscal Year 2012 3Varian Medical Systems Reports Results for Second Quarter of Fiscal Year 2012 4Varian Medical Systems Reports Results for Second Quarter of Fiscal Year 2012 5Varian Medical Systems Reports Results for Second Quarter of Fiscal Year 2012 6Varian Medical Systems Reports Results for Second Quarter of Fiscal Year 2012 7Varian Medical Systems Reports Results for Second Quarter of Fiscal Year 2012 8Nearly 300 Medical Device, Healthcare Professionals Attend First National Conference on Value-driven Engineering 2Nearly 300 Medical Device, Healthcare Professionals Attend First National Conference on Value-driven Engineering 3Nearly 300 Medical Device, Healthcare Professionals Attend First National Conference on Value-driven Engineering 4
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: