Navigation Links
JCI early table of contents for June 24, 2013
Date:6/24/2013

ticles/view/69399?key=bb81f4707f101fecbcaa">http://www.jci.org/articles/view/69399?key=bb81f4707f101fecbcaa


Gene dysregulation underlies preeclampsia

Preeclampsia is a medical condition affecting 4-8% of pregnancies that is characterized by high maternal blood pressure, excess protein in maternal urine, and reduced fetal growth. If left untreated, it can develop into eclampsia, which causes life threatening seizures. Apart from delivery, there is no known cure. In this issue of the Journal of Clinical Investigation, researchers led by Susan Fisher at the University of California, San Francisco, examined cytotrophoblast cells, which help to form the placenta, from women that developed preeclampsia and healthy controls. They found that the cytotrophoblasts from patients with preeclampsia exhibited changes in gene expression, particularly in the gene SEMA3B. Increased expression of SEMA3B in normal cytotrophoblasts recreated some of the features of the cytotrophoblasts from patients with preeclampsia. In the accompanying Attending Physician article, Roberto Romero of the National Institute of Child Health and Development discusses how these findings are our first insight into the pathogenesis of preeclampsia.

TITLE: Reversal of gene dysregulation in cultured cytotrophoblasts reveals possible causes of preeclampsia

AUTHOR CONTACT: Michael McMaster
University of California San Francisco, San Francisco, CA, USA
Phone: 415-514-0172; E-mail: mcmaster@cgl.ucsf.edu

View this article at: http://www.jci.org/articles/view/66966?key=21b97f984b68c6c0c8d7

ACCOMPANYING ATTENDING PHYSICIAN

TITLE: Preeclampsia: a link between trophoblast dysregulation and an anti-angiogenic state

AUTHOR CONTACT: ROBERTO ROMERO
PERINATOLOGY
'/>"/>

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8 9

Related medicine news :

1. New Stool Test Might Aid in Early Detection of Colon Cancer
2. An Early Start for Your Child with Autism
3. Early Study Finds Some Promise for Lung Cancer Vaccine
4. Treat Rheumatoid Arthritis Early and Aggressively: Guidelines
5. JCI early table of contents for April 9, 2012
6. Eye Tremors May Aid Early Diagnosis of Parkinsons: Study
7. Nearly 1 in 4 grandparents store prescription medicines where children can easily find them
8. First contact: Early intervention key in diagnosis and treatment of serious mental illness
9. Brain Tumor Vaccine Shows Promise in Early Trial
10. Role of Screening, Monitoring in Early Kidney Disease Unclear
11. Detecting malaria early to save lives: New optical technique promises rapid and accurate diagnosis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/22/2014)... to provide better services, LunaDress has updated its website with ... that a suitable cocktail party dress is crucial for every ... dresses supplier’s high quality items are offered at attracting prices, ... industry, LunaDress understands that it is not easy to provide ... the professional level and innovation ability. The growth of sales ...
(Date:11/22/2014)... November 22, 2014 Domestic farmgate ... slightly in 2009-10, due to a fall in ... industry products amid the global financial crisis. ... strength of Australian dairy manufacturers on the international ... products outweighed supply growth, primarily due to supply ...
(Date:11/22/2014)... This month has been a historical time ... received many positive reviews from some renowned review websites. Recently, ... by launching a new selection of wonderful sexy wedding dresses ... enjoy free shipping and up to an 80% discount on ... always find the most suitable dress at Angeldress.co.uk, which has ...
(Date:11/22/2014)... The Sports Conflict Institute is pleased to announce ... of conflict resolution professionals. Baroff comes to SCI as an ... over 30 years experience as an arbitrator, educator, and ombuds ... connect with SCI and bring my conflict resolution skills and ... a complete sports focus,” says Baroff. , “Roy has a ...
(Date:11/22/2014)... November 22, 2014 “Greenfield Naturals” was ... Tech Report , which features the latest and coolest ... expert and reporter for NewsWatch, conducted the product review ... the flavor of your water. , From pollution to ... important that everything is done to remove these chemicals, ...
Breaking Medicine News(10 mins):Health News:LunaDress Unveils Fabulous Cocktail Party Dresses 2Health News:Butter and Dairy Product Manufacturing in Australia Industry Market Research Report Now Updated by IBISWorld 2Health News:Butter and Dairy Product Manufacturing in Australia Industry Market Research Report Now Updated by IBISWorld 3Health News:Butter and Dairy Product Manufacturing in Australia Industry Market Research Report Now Updated by IBISWorld 4Health News:Sexy Wedding Dresses with Special Discounts Launched by Angeldress.co.uk 2Health News:SCI Announces New Team Member Roy Baroff 2Health News:SCI Announces New Team Member Roy Baroff 3Health News:An Easy Home Solution to Get Better Tasting Water was Featured on NewsWatch Television on October 30, 2014 2
... a busy man today; fielding complaints from the public, a ... taken to court, from an NGO.// ,The yoga ... hold the key to curing AIDS by performing yoga and ... earlier rubbished these statements, saying while he supported the practice ...
... colleague are set to drastically lower the cost of medicines ... companies. ,Sunil Shaunak, professor of infectious diseases at Imperial ... Pharmacy are leading clinical trials in India for a drug ... a way to invent new medicines and get them to ...
... Indian pharma major Ranbaxy Laboratories Limited has received the ... to manufacture and market generic hypertension drug Atenolol in ... tablets of 25 mg, 50 mg, and 100 mg ... from the first quarter of 2007, the company said ...
... adolescent girls in Haryana will receive more supplementary// ... needs. ,Social Welfare and Health Minister Kartar ... needs provided to these categories under the Integrated ... said 1.1 million children below the age of ...
... RN and colleagues and published in the January 1st ... of its kind, finds that sleep disturbances are common ... suicidality. ,Researchers of Sahlgrenska University Hospital in ... of 18-68, who were admitted to medical units or ...
... Dentists frown down upon the habit of offering fruit ... from mealtimes, its ideally better to avoid sugary ... suck up drinks’ aided by the sipper attached. The American ... hasten tooth decay. ,Sipper cups do help to avoid ...
Cached Medicine News:Health News:NRI Doctor's R&D Model in India to Slash Cost of Drugs 2Health News:Sleep Disturbances, Nightmares - Common Among Suicide Attempters: Report 2
(Date:11/21/2014)... DUBLIN, Ohio and MELVILLE, N.Y. ... (NYSE: CAH ), one of the world,s ... (NASDAQ: HSIC ), the world,s largest provider ... animal health and medical practitioners, today announced that the ... provide one of the most comprehensive service and product ...
(Date:11/21/2014)... 2014 /PRNewswire/-- CANTEL MEDICAL CORP. (NYSE: CMN ) announced ... will be presenting at the 26 th Annual Piper ... New York . The formal presentation is ... In addition, Mr. Krakauer and Jorgen B. Hansen , ... during the day. An audio webcast will ...
(Date:11/21/2014)... Nov. 20, 2014  The acceptance of two ... AAGL Global Congress demonstrates continued interest in the ... provide bowel control. One of the abstracts, presented by ... Division Chief of Urogynecology and Reconstructive Pelvic Surgery ... Award for Best Written Abstract on Urogynecology/Pelvic Floor ...
Breaking Medicine Technology:Cardinal Health And Henry Schein Enter Into Long-Term Strategic Agreement To Serve Physician Offices 2Cardinal Health And Henry Schein Enter Into Long-Term Strategic Agreement To Serve Physician Offices 3Cardinal Health And Henry Schein Enter Into Long-Term Strategic Agreement To Serve Physician Offices 4Cardinal Health And Henry Schein Enter Into Long-Term Strategic Agreement To Serve Physician Offices 5LIFE Study Prominently Featured at Minimally Invasive Gynecology Conference 2LIFE Study Prominently Featured at Minimally Invasive Gynecology Conference 3
... Nov. 9, 2010 As obesity rates and the ... the 2010 mHealth Summit in Washington D.C. is bringing ... discuss the opportunities to address pressing public health issues ... the pioneer in developing wearable body monitoring systems, recently ...
... 2010 The clinical practice guideline recently issued by ... spinal compression fractures has left the medical community scratching ... fractures (also called vertebral compression fractures or VCFS) are ... affects an estimated 44 million Americans, or 55 percent ...
Cached Medicine Technology:Results of Two New Clinical Studies Show Promise of Emerging Mobile Health Technology to Combat Obesity Epidemic 2Results of Two New Clinical Studies Show Promise of Emerging Mobile Health Technology to Combat Obesity Epidemic 3AAOS Clinical Guideline for Treating Spinal Compression Fractures Presents More Questions Than Answers for Medical Community 2AAOS Clinical Guideline for Treating Spinal Compression Fractures Presents More Questions Than Answers for Medical Community 3
... Marco has added the NEW Evolution ... Diagnostic Systems. The Evolution offers the convenience ... is priced well below other automated refraction ... control of the refraction process through the ...
The Manual Table Base is elevated with an easy to reach elevating wheel for smooth operation. The table base will accept a slit lamp, a single table top, or a double tabletop for more than one instru...
... Only Marco could offer you a choice of ... EverLight Chart Projector uses a halogen bulb for ... typical use. The Marco Chart Projector offers a ... that includes a thermistor for extended bulb life. ...
The Marco Encore Chair continues the Marco tradition of useful features and unsurpassed quality. Its attractive, modern look blends beautifully with any office decore....
Medicine Products: