Navigation Links
JCI early table of contents for Jan. 25, 2013
Date:1/25/2013

Prostate cancer cells thrive on stress

Prostate cancer patients have increased levels of stress and anxiety; however, several recent studies have found that men who take drugs that interfere with the stress hormone adrenaline have a lower incidence of prostate cancer. In this issue of the Journal of Clinical Investigation George Kulik and colleagues at Wake Forest University examined the relationship between stress and cancer progression in a mouse model of prostate cancer. Kulik and colleagues found that mice that had been subjected to stress (exposed to the scent of a predator) exhibited a significantly reduced response to a drug that induces cancer cell death compared to their unstressed counterparts. Administration of adrenaline also blocked cancer cell death. Conversely, drugs that inhibited adrenaline signaling ablated the effect of stress on prostate cancer. These findings suggest that beta-blockers, which are used for the treatment of high blood pressure and block the effects of adrenaline, could increase the efficacy of anti-cancer therapies. In a companion commentary, Anil Sood and colleagues at MD Anderson Cancer Center discuss additional studies that will be required to move these findings from bench to bedside.

TITLE:
Behavioral stress accelerates prostate cancer development in mice

AUTHOR CONTACT:
George Kulik
Wake Forest University Health Sciences, Winston-Salem, NC, USA
Phone: 336-713-6750; E-mail: gkulik@wakehealth.edu

View this article at: http://www.jci.org/articles/view/63324?key=6ae78db845f6f7d9379b

ACCOMPANYING COMMENTARY

TITLE:
Why stress is BAD for cancer patients

AUTHOR CONTACT:
Anil Sood
M. D. Anderson Cancer Center, Houston, TX, USA
Phone: 713-745-5266; Fax: 713-792-7586; E-mail:

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8 9

Related medicine news :

1. Dont ignore the snore: Snoring may be early sign of future health risks
2. NIH-developed candidate dengue vaccine shows promise in early-stage trial
3. Nearly half of children under 2 years of age receive some vaccinations late
4. Study Finds Nearly Half of U.S. Kids Are Under-Vaccinated
5. JCI early table of contents for Jan. 16, 2013
6. Generic HIV treatment strategy could save nearly $1 billion annually but may be less effective
7. Early Parkinsons Patients May Suffer Some Symptoms in Silence
8. Early Ovary Removal May Be Tied to Lapses in Memory, Thinking
9. Fox Chase researchers discover novel role of the NEDD9 gene in early stages of breast cancer
10. Depressed Stroke Survivors May Face Higher Early Death Risk
11. Teenagers with a low muscular strength have a higher risk of dying early form heart disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/20/2014)... 20, 2014 With a mere 19 ... Crist made a brief fundraising stop at the ... , Fresh from a debate last night with his ... stage for the first seven minutes because Crist had ... described the incident in one word: "weird." , Before ...
(Date:10/20/2014)... The Advocator Group, LLC is proud ... for Suicide Prevention’s (AFSP) Out of the Darkness walk ... that hosts hundreds of community walks throughout the country ... to help understand and prevent suicide through not only ... , The Advocator Group shares this passion for ...
(Date:10/20/2014)... (PRWEB) October 20, 2014 Women’s health ... in Obstetrics & Gynecology of Columbus, Inc., A Division ... healthcare services to more than 100,000 patients annually. Dr. ... all ages and stages of a women’s life. She ... locations in Westerville and Dublin. , Dr. Murphy ...
(Date:10/20/2014)... (PRWEB) October 20, 2014 hc1.com ... a secure cloud solution that enables healthcare organizations ... the ultimate healthcare-specific customer relationship management (“CRM”) solution. ... the unique needs of the healthcare industry, the ... for providers and patients by combining healthcare CRM, ...
(Date:10/20/2014)... Angeles, CA (PRWEB) October 20, 2014 ... fitness expertise, nutritional coaching, corporate wellness programming, authorship, international ... CPT, is excited to announce the release of the ... , After many years of coaching thousands of individuals ... nutrition tracking app that does not require calorie counting ...
Breaking Medicine News(10 mins):Health News:At Crist Fundraiser, Dan Newlin Says, "No More Robert Germans," Will Seek Changes to Florida Missing Persons Law 2Health News:At Crist Fundraiser, Dan Newlin Says, "No More Robert Germans," Will Seek Changes to Florida Missing Persons Law 3Health News:The Advocator Group, LLC is Proud to Participate in an Out of the Darkness Community Walk, October 25th, to Increase Suicide Awareness 2Health News:The Advocator Group, LLC is Proud to Participate in an Out of the Darkness Community Walk, October 25th, to Increase Suicide Awareness 3Health News:OhioHealth Welcomes New Women’s Health Specialist to MaternOhio Specialists in Obstetrics & Gynecology of Columbus, Inc. 2Health News:OhioHealth Welcomes New Women’s Health Specialist to MaternOhio Specialists in Obstetrics & Gynecology of Columbus, Inc. 3Health News:Healthcare Relationship Management (HRM) Leader hc1.com® Launches hc1® Quick Start™ 2Health News:JZ Fitness Nutrition App Launches on iTunes 2Health News:JZ Fitness Nutrition App Launches on iTunes 3
... March 19 Mirion Technologies, the,leading global provider ... protection industry, will showcase two new products at ... Beijing from,March 25th - 28th., Mirion,s Health ... Body Contamination Monitor. The TwoStep Exit monitor is ...
... March 19, 2008 Chronic fatigue syndrome ... debilitating diseases with no confirmed cause and limited ... literature study propose a simplified treatment process that ... these diseases. , Kent Holtorf, M.D., medical director ...
... SAN DIEGO, March 19 Cardium Therapeutics,(Amex: ... InnerCool Therapies announced today that,InnerCool has entered ... one of Australia,s leading medical device distributors ... agreement, Lifehealthcare will have,exclusive marketing, sales and ...
... March 19 Forest Laboratories, Inc.,(NYSE: FRX ) ... -,Scientific Affairs and President of the Forest Research Institute ... March 31, 2008., (Logo: http://www.newscom.com/cgi-bin/prnh/20001011/FORESTLOGO ), ... Officer of,Forest, stated: "The Board and I wish to ...
... Open Standard Data Management ... Systems for Company, ... of digital radiography (DR), PACS (Picture Archiving and,Communications System) and practice ... Dennis,Ballance, DVM, as division manager of the newly-formed Eklin Data Services,Division. ...
... Inc.,(Nasdaq: ABAX ), a medical products company ... Severson, CEO and,President, will present at Sidoti & ... Forum on Tuesday, March 25, 2008 at,11:00 a.m. ... Grand Hyatt in New York,City., About Abaxis, ...
Cached Medicine News:Health News:Mirion Technologies to Showcase New Product Offerings for the Nuclear Industry During 10th Annual China International Nuclear Industry Exhibition 2Health News:Data study suggests cortisol could alleviate for chronic fatigue syndrome and fibromyalgia 2Health News:Cardium's InnerCool Therapies Unit Announces Australian Distribution Agreement for CoolBlue and Rapid Blue Systems 2Health News:Cardium's InnerCool Therapies Unit Announces Australian Distribution Agreement for CoolBlue and Rapid Blue Systems 3Health News:Cardium's InnerCool Therapies Unit Announces Australian Distribution Agreement for CoolBlue and Rapid Blue Systems 4Health News:Cardium's InnerCool Therapies Unit Announces Australian Distribution Agreement for CoolBlue and Rapid Blue Systems 5Health News:Cardium's InnerCool Therapies Unit Announces Australian Distribution Agreement for CoolBlue and Rapid Blue Systems 6Health News:Cardium's InnerCool Therapies Unit Announces Australian Distribution Agreement for CoolBlue and Rapid Blue Systems 7Health News:Cardium's InnerCool Therapies Unit Announces Australian Distribution Agreement for CoolBlue and Rapid Blue Systems 8Health News:Cardium's InnerCool Therapies Unit Announces Australian Distribution Agreement for CoolBlue and Rapid Blue Systems 9Health News:Forest Laboratories Announces Resignation of Ivan Gergel, MD 2Health News:Eklin Medical Names Ballance Head of New Data Services Division 2Health News:Eklin Medical Names Ballance Head of New Data Services Division 3
(Date:10/22/2014)... 2014  CryoLife, Inc. (NYSE: CRY ), ... on cardiac and vascular surgery, announced today that ... Officer, has been elected to the Company,s Board of ... G. Anderson , Executive Chairman of CryoLife, stated, "Since joining ... an excellent leader who is well positioned to maximize ...
(Date:10/22/2014)... 2014 Oramed Pharmaceuticals Inc. ... pharmaceutical company focused on the development of oral ... results from its Phase IIa clinical trial of ... treat type 1 diabetes. The trial was conducted in ... a U.S. Food and Drug Administration (FDA) Investigational ...
(Date:10/22/2014)... , Oct. 21, 2014  Early symptoms of ... or unnoticed, but new technology, coupled with yearly, ... leading to earlier detection of eye diseases, including ... million Americans. If left untreated, these diseases can ... Recently, optometric researchers have deployed ...
Breaking Medicine Technology:Pat Mackin Joins CryoLife Board of Directors 2Pat Mackin Joins CryoLife Board of Directors 3Oramed Pharmaceuticals Reports Positive Top-Line Data from U.S. Phase IIa Trial with Oral Insulin in Type 1 Diabetes 2Oramed Pharmaceuticals Reports Positive Top-Line Data from U.S. Phase IIa Trial with Oral Insulin in Type 1 Diabetes 3Oramed Pharmaceuticals Reports Positive Top-Line Data from U.S. Phase IIa Trial with Oral Insulin in Type 1 Diabetes 4Technology Advancements Enhance Early Detection of Eye Diseases Associated with Diabetes 2Technology Advancements Enhance Early Detection of Eye Diseases Associated with Diabetes 3
... Cempra Pharmaceuticals Inc. today announced that Prabhavathi Fernandes, ... Capital Markets 6th Annual Healthcare Conference on November 17, 2009 ... New York City. Dr. Fernandes will provide an overview ... treatment of drug-resistant pathogens including MRSA. , About Cempra ...
... Nov. 13 Warner Chilcott plc (Nasdaq: WCRX ... its ordinary shares by certain selling shareholders. The ... DLJ Merchant Banking, J.P. Morgan Partners (advised by CCMP ... institutional investors and members of the Company,s senior management. ...
Cached Medicine Technology:Warner Chilcott Announces Secondary Equity Offering 2Warner Chilcott Announces Secondary Equity Offering 3Warner Chilcott Announces Secondary Equity Offering 4
Symbia T, a TruePoint SPECTCT system, combines a dual-detector variable angle gamma camera with a CT scanner optimized for rapid, accurate attenuation correction of the nuclear data....
... analyzer and data management system ,RADIANCE ... traditional needs of data management systems (DMS), ... management of STAT analyzer systems., ,The RADIANCE ... solution for both STAT analyzers and hospital ...
... is a comprehensive IT solution that ... admission to follow-up. This scalable solution ... diagnostic tools from syngo Dynamics with ... longitudinal clinical repository that becomes a ...
... the AXIOM Artis dBC Magnetic Navigation ... navigation system equipped with digital flat ... is uniquely capable of improving the ... to facilitate increased efficiency and productivity ...
Medicine Products: