Navigation Links
JCI early table of contents for Jan. 2, 2013
Date:1/2/2013

Bacterial imbalance contributes to intestinal inflammation and carcinogenesis

Instability in the composition of gut bacterial communities (dysbiosis) has been linked to common human intestinal disorders, including inflammatory bowel disease and colorectal cancer; however, it is unclear if dysbiosis can instigate disease or if it is a consequence of the underlying disorder. In this issue of the Journal of Clinical Investigation, researchers led by Mathias Chamaillard at the University Lille Nord de France in Lille, France, examined intestinal inflammation and tumorigenesis in a mouse model of dysbiosis. Dysbiosis enhanced intestinal inflammation and increased the risk for inflammation-associated colon cancer. Treatment with antibiotics or transplantation of fecal material from normal mice reduced disease risk and instigated long-term, beneficial alterations in intestinal bacteria. Conversely, transplantation of normal mice with dysbiotic fecal material increased intestinal inflammation and enhanced the risk of inflammation-associated colon cancer. These results demonstrate that gut bacterial communities play an integral role in protecting against intestinal inflammation and associated tumorigenesis.

TITLE:
NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer

AUTHOR CONTACT:
Mathias Chamaillard
Inserm, Lille, , FRA
Phone: +33359317427; Fax: +33359317480; E-mail: mathias.chamaillard@inserm.fr

View this article at: http://www.jci.org/articles/view/62236?key=555e9b1899800b97fd0b


AUTOIMMUNITY

Identifying the molecular causes of vision loss in demyelinating disease

Demyelinating diseases, such as multiple sclerosis (MS), are frequently associated with the progressive loss of vision. The retinal nerve da
'/>"/>

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. New Stool Test Might Aid in Early Detection of Colon Cancer
2. An Early Start for Your Child with Autism
3. Early Study Finds Some Promise for Lung Cancer Vaccine
4. Treat Rheumatoid Arthritis Early and Aggressively: Guidelines
5. JCI early table of contents for April 9, 2012
6. Eye Tremors May Aid Early Diagnosis of Parkinsons: Study
7. Nearly 1 in 4 grandparents store prescription medicines where children can easily find them
8. First contact: Early intervention key in diagnosis and treatment of serious mental illness
9. Brain Tumor Vaccine Shows Promise in Early Trial
10. Role of Screening, Monitoring in Early Kidney Disease Unclear
11. Detecting malaria early to save lives: New optical technique promises rapid and accurate diagnosis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... As the use of electronic health record becomes widespread ... implementation of the Affordable Care Act, the quantity of ... analytic purposes will also dramatically increase. Additionally, experts ... that analyze large quantities of data for the purpose ... the value of patient care a process that ...
(Date:7/10/2014)... (HealthDay News) -- Teens who are sensitive to light ... develop emotional symptoms such as anxiety and depression, a ... that may exacerbate issues teens experience after concussion may ... making decisions about when to return to play and ... study authors Lisa Koehl and Dong Han, of the ...
(Date:7/10/2014)... HealthDay Reporter THURSDAY, July 10, 2014 (HealthDay ... of calorie information on menus, if it,s available, to decide ... study. Women in particular review the menu labeling, said ... the U.S. Centers for Disease Control and Prevention. ... help choose their meal, compared with just under half of ...
(Date:7/10/2014)... captured with a microchip-based device developed at the Massachusetts ... the MGH Cancer Center can be cultured to establish ... In the July 11 issue of Science , ... accurately reflect a tumor,s genetic mutation over time and ... can culture cells from the blood that represent those ...
(Date:7/10/2014)... Human Services (HHS) has announced a three-year grant to ... totaling $4.7 million to support a new national model ... , Titled "Evidence-Conformant Oncology Care," the project will ... care for adult cancer patients with late-stage disease, significant ... , "We believe that the best cancer ...
Breaking Medicine News(10 mins):Health News:Six cases where big data can reduce healthcare costs 2Health News:Six cases where big data can reduce healthcare costs 3Health News:Six cases where big data can reduce healthcare costs 4Health News:Some Teens May Face Emotional Problems After Concussion 2Health News:60 Percent of Diners Use Calorie Labeling When Posted: CDC 2Health News:60 Percent of Diners Use Calorie Labeling When Posted: CDC 3Health News:Cultured CTCs reveal genetic profile, potential drug susceptibility of breast cancer cells 2Health News:Cultured CTCs reveal genetic profile, potential drug susceptibility of breast cancer cells 3Health News:UH Case Medical Center awarded $4.7 million grant from HHS 2Health News:UH Case Medical Center awarded $4.7 million grant from HHS 3
... expert says physicians have unique opportunity to help parents ... ... Washington, DC (Vocus) October 1, ... and their families understand the http://www.childrensnational.org/?utm_source=pressrelease&utm_medium=9_30&utm_campaign=driving_safety [importance of responsible ...
... recent headlines from Wall Street portend tougher times on the horizon, ... smart about their marketing. So says Helmut G. Flasch, of Flasch ... he has shown countless medical professionals how to expand their practices ... ...
... Reduce Claim Fraud and Costs by 30 Percent, ... Euronext: ILO, ISIN: FR0004042364) today announced that Swiss ... is using ILOG,JRules(R) to automate its medical claims ... has been able to reduce,unnecessary medical treatments, provide ...
... the Oct. 1 issue of the journal Sleep ... ideation and attempts, and the use of alcohol, cannabis and ... the presence of insomnia in adolescents increases the risk of ... of these problems. Results indicate that adolescents who had symptoms ...
... , A study conducted by researchers at Mayo Clinic ... enhanced response to the weight loss drug sibutramine, while ... no weight. , The findings are published in the ... , In this randomized, double-blind, placebo-controlled study, Mayo researchers ...
... simple questionnaire can reliably predict whether they will ... Hopkins researchers suggest in a new study. The ... benefit from additional preoperative preparation to ensure they ... exercise, a factor that can greatly affect their ...
Cached Medicine News:Health News:Healthcare Providers Can Help Reduce Teen Driving Deaths 2Health News:Healthcare Providers Can Help Reduce Teen Driving Deaths 3Health News:Medical Marketing Expert Offers Dentists Tips for Thriving Down Economy After the Wall Street Dilemma 2Health News:Medical Marketing Expert Offers Dentists Tips for Thriving Down Economy After the Wall Street Dilemma 3Health News:Swiss Medical Group Selects ILog JRules to Streamline Claims Processing 2Health News:Swiss Medical Group Selects ILog JRules to Streamline Claims Processing 3Health News:Adolescent insomnia linked to depression and substance abuse during adolescence and young adulthood 2Health News:Genes affect weight loss drug effectiveness 2Health News:Will patients stick to physical therapy? Questionnaire can help doctors predict 2Health News:Will patients stick to physical therapy? Questionnaire can help doctors predict 3
(Date:1/15/2014)...  Celsion Corporation (the "Company") (NASDAQ: CLSN ) ... investors to purchase an aggregate of approximately $15 million ... direct offering, led by a dedicated health care fund. ... with these investors pursuant to which the Company agreed ...
(Date:1/15/2014)... Shire plc (LSE: SHP, NASDAQ: SHPG ... (OFT) approval condition to the announced tender offer for all of ... As a result of the waiver, the transaction is no longer ... offer on January 24, 2014 following the currently scheduled expiration time, ...
(Date:1/15/2014)... YORK , January 15, 2014 ... Ltd., the exclusive worldwide distributor of highly sophisticated agro-breeding ... on January 7, 2014, the Company,s board of directors ... Weiner as its new member of the board. ...
Breaking Medicine Technology:Celsion Corporation Announces $15 Million At-The-Market Registered Direct Offering 2Celsion Corporation Announces $15 Million At-The-Market Registered Direct Offering 3Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 2Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 3BreedIT (OTC: BRDT) Appoints Chemistry and Pharmaceutical Industry Expert Dr. Ben-Zion Weiner to Its Board of Directors 2BreedIT (OTC: BRDT) Appoints Chemistry and Pharmaceutical Industry Expert Dr. Ben-Zion Weiner to Its Board of Directors 3
MDI will work with your facility to determine the best interim lab to fit your needs and your site....
... 300 ,Oblique 45, ,Type 330 ,Straight, ... by setting the illumination between lenses ... ideal for use in ophthalmology and ... conventional compact microscope can; an advanced ...
... same as the model SP-8800 with one big exception. ... This mode has its own fixation targets to allow ... allows you to select an area on the cornea ... to calculate averages of multiple readings in any one ...
... MedCath is the largest and most experienced ... networks in the United States. Mobile laboratories ... a daily basis, from one hospital to ... geographic area. Each mobile laboratory is fully ...
Medicine Products: