Navigation Links
JCI early table of contents for Feb. 22, 2013
Date:2/22/2013

How to mend a broken heart: advances in parthenogenic stem cells

Parthenogenesis is a form of asexual reproduction during which unfertilized eggs begin to develop as if they had been fertilized. It occurs naturally in many plants and a few invertebrate (some bees, scorpions, parasitic wasps) and vertebrate animals (some fish, reptiles, and amphibians), but does not occur naturally in mammals. In 2007, researchers were able to chemically induce human egg cells to undergo parthenogenesis. The resulting parthenogenote has properties similar to an embryo, but cannot develop further. In this issue of the Journal of Clinical Investigation, Wolfram Zimmerman and colleagues at Georg-August-Universitt Gttingen in Gttingen, Germany, demonstrated that cells from the parthenogenote function as embryonic stem cells and maintain the capacity to develop into different types of tissue. Further, they used parthenogenic stem cells to make cardiomyocytes and engineered heart muscle (myocardium) that exhibited the structural and functional properties of normal myocardium. The engineered myocardium could then be used to engraft the mice that had contributed the eggs for parthenogenesis. These studies demonstrate that parthenogenic stem cells can be used for tissue engineering. In a companion commentary, Michael Schneider of the Imperial College of London discusses how these findings could impact the development of cell replacement therapies.

TITLE:
Parthenogenetic stem cells for tissue engineered heart repair

AUTHOR CONTACT:
Wolfram Zimmermann
Georg-August-Universitt Gttingen, Gttingen, DEU
Phone: +49 (0) 551 39-57 81; E-mail: w.zimmermann@med.uni-goettingen.de

View this article at: http://www.jci.org/articles/view/66854?key=31d6143cd2894a5b80d5

AC
'/>"/>

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation
Source:Eurekalert

Page: 1 2 3 4 5 6 7

Related medicine news :

1. Gene Therapy Shows Early Promise for Heart Failure
2. Early life stress may take early toll on heart function
3. Early Exposure to Gluten May Help Babies Avoid Celiac Risk: Study
4. Youth Smoking, Obesity May Lead to Early Death
5. Early education closes achievement gap, brings societal benefits
6. JCI early table of contents for Feb. 15, 2013
7. Those Childhood Piano Lessons Should Start Early
8. Deep Brain Stimulation May Help in Early Stages of Parkinsons
9. Researchers identify genetic root to early-onset prostate cancer
10. Early Dental Care Can Help Keep Kids Smiling for Years to Come
11. JCI early table of contents for Feb. 8, 2013
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... (SACRAMENTO, Calif.) An international team led by researchers ... protein complex, which plays a key role in cell ... process. This is the first time the complex has ... could make cyclin B1/Cdk1 an excellent target to control ... medicine. The research was published online today in the ...
(Date:4/17/2014)... uncommon these days to find a colored ribbon representing a ... cancer. But what color ribbon does one think of with ... color, for many suffering from the disease, black may be ... study consisting of lung cancer patients, primarily smokers between the ... light on the stigma often felt by these patients, the ...
(Date:4/17/2014)... A new study has found that India,s shocking rates ... debt-ridden farmers who are clinging to tiny smallholdings ... ,cash crops, such as cotton and coffee, that are ... supports a range of previous case studies that point ... sector following the ,liberalisation, of the nation,s economy during ...
(Date:4/17/2014)... the leading weapon against the deadly disease could be ... indicating it simply needs to be administered differently. , ... anti-malarial drug chloroquine in treating and preventing the mosquito-bourne ... a million people each year around the world. , ... chloroquine, but research carried out at the Australian National ...
(Date:4/16/2014)... Celldex Therapeutics, Inc. (NASDAQ: CLDX) announced today that final ... solid tumors, including long-term patient follow-up, have been published ... 232). The data demonstrate robust antibody and T cell ... very advanced cancers and suggest that CDX-1401 may predispose ...
Breaking Medicine News(10 mins):Health News:Dual role: Key cell division proteins also power up mitochondria 2Health News:Unraveling the 'black ribbon' around lung cancer 2Health News:New evidence of suicide epidemic among India's 'marginalized' farmers 2Health News:New evidence of suicide epidemic among India's 'marginalized' farmers 3Health News:Scientists find new way to fight malaria drug resistance 2Health News:Celldex's Phase 1 study of CDX-1401 published in Science Translational Medicine 2Health News:Celldex's Phase 1 study of CDX-1401 published in Science Translational Medicine 3Health News:Celldex's Phase 1 study of CDX-1401 published in Science Translational Medicine 4
... ... in Italy, in conjunction with a team of doctors from the ... confirming that Pecorino Romano Cheese contains high amounts of CLA (Conjugated ... food groups. The study reveals that even in small amounts, ...
... Yummy commercial food smells contain noxious gases, researchers say ... aromas that restaurants emit are actually a type of ... health and the environment, U.S. researchers report. , Gases ... out by commercial food cooking, according to Deborah Gross, ...
... ... for your interview. One Portland, Oregon business is providing support—literally—for today’s job seekers. ... (PRWEB) March 24, ... ), today announced a special discount offer for those seeking employment and looking for ...
... ... a healthcare consulting firm, launches new corporate website with enhanced content, navigation and performance. ... ... consulting services for the healthcare industry, is pleased to announce that it has launched ...
... ... and with celebrity appeal, generating success in a difficult economy. , ... (PRWEB) March 24, 2010 -- The ... celebrities., , ,Leeza Gibbons, popular entertainment personality and National Spokesperson for ZERONA, has proven ...
... ... asks that you join in recognizing all physicians on National Doctor,s Day, March 30 -- ... ... March 30 is National Doctor’s Day. The American Board of Physician Specialties (ABPS) ...
Cached Medicine News:Health News:Say Cheese! New Study Confirms Health Benefits of Pecorino Romano Cheese 2Health News:What's Cookin'? It Could Be Air Pollution 2Health News:Your Posture Can Make or Break Your Job Interview; PostureNOW Offers 33% Off Its Posture Corrective Brace to Job Seekers Nationwide 2Health News:Leading Healthcare Human Resource Consulting Firm, Integrated Healthcare Strategies, Launches New Website 2Health News:Leading Healthcare Human Resource Consulting Firm, Integrated Healthcare Strategies, Launches New Website 3Health News:Leeza Gibbons and ZERONA Equals a Winning Combination 2Health News:American Board of Physician Specialties (ABPS) Celebrates Doctor's Day 2010 2
(Date:1/14/2014)... , Jan. 14, 2014   NuAire , a manufacturer of ergonomically ... with Hitachi Koki of Japan ... North America . NuAire will utilize its network of ... Canada to offer assistance in application use, ...
(Date:1/14/2014)... Oligomerix, Inc. , a privately held company pioneering the ... and related neurodegenerative disorders, announced today the relocation of ... as of January 15, 2014 and expanded lease ... College. Oligomerix, which is focused on the ...
(Date:1/14/2014)...   Evidera , a leading provider of evidence-based solutions ... Drug Evaluation and Research (CDER), U.S. Food and Drug ... for a patient-reported outcome (PRO) measure in drug development: ... [EXACT] for Measurement of Symptoms of Acute Bacterial Exacerbation ...
Breaking Medicine Technology:NuAire announces sales and service of Hitachi Koki centrifuges in North America 2Oligomerix Relocates Corporate Headquarters and Secures Additional Laboratory Space from New York Medical College 2Evidera Announces Release of FDA Draft Guidance on Use of the "EXACT" to Measure Symptoms of COPD Exacerbations 2Evidera Announces Release of FDA Draft Guidance on Use of the "EXACT" to Measure Symptoms of COPD Exacerbations 3Evidera Announces Release of FDA Draft Guidance on Use of the "EXACT" to Measure Symptoms of COPD Exacerbations 4
FlexiSlip™ Plastic coated malleable metal core. Single use, Sterile, Latex Free. Soft distal tip flexes to reduce risk of trauma to patient. Malleable metal core is easy to shape. Low friction ...
Surgical Stainless Steel Child Stylette....
Surgical Stainless Steel Adult 16.5....
Ultra-Slip™ endotracheal tube guide for single-patient use only., ,Caution: Not MRI Compatible....
Medicine Products: