Navigation Links
JAMA commentary contends vitamin therapy can still reduce stroke
Date:12/21/2011

A commentary by Dr. David Spence of The University of Western Ontario and Dr. Meir Stampfer of the Harvard School of Public Health in today's Journal of the American Medical Association (JAMA) argues that vitamin therapy still has a role to play in reducing stroke.

Vitamin B therapy was once widely used to lower homocysteine levels. Too much of this amino acid in the bloodstream was linked to increased risk of stroke and heart attack. But several randomized trials found lowering homocysteine levels with B vitamins did not result in a cardiovascular benefit. And a study by Dr. Spence, a scientist with the Robarts Research Institute at Western's Schulich School of Medicine & Dentistry, found Vitamin B therapy actually increased cardiovascular risk in patients with diabetic nephropathy.

Dr. Spence says this commentary provides insights that overturn the widespread belief that "homocysteine is dead." He says two key issues have been overlooked in the interpretation of the clinical trials: the key role of vitamin B12, and the newly recognized role of renal failure.

"It is now clear that the large trials showing no benefit of vitamin therapy obscured the benefit of vitamin therapy because they lumped together patients with renal failure and those with good renal function. The vitamins are harmful in renal failure, and beneficial in patients with good renal function, and they cancel each other out," says Dr. Spence, the author of "How to Prevent Your Stroke." The authors also contend most of the trials did not use a high enough dose of vitamin B12.


'/>"/>

Contact: Kathy Wallis
kwallis3@uwo.ca
519-661-2111 x81136
University of Western Ontario
Source:Eurekalert

Page: 1

Related medicine news :

1. Global Health Defined as Public Health in a New Lancet Commentary by the Association of Schools of Public Health (ASPH)
2. Cinergy Health Commentary on Healthcare Summit
3. Cinergy Health Commentary on House Healthcare Bill
4. New commentary suggests alternatives to routine use of OTC cold/cough meds in children
5. Commentary suggests alternatives to routine use of OTC cold/cough meds in children
6. Commentary: When creating a new institute, the devils in the details
7. CT Scans May Pose Less Cancer Risk Than Thought, Study Contends
8. Many Find Solace in Charlie Sheen Drama, Expert Contends
9. Chiropractic Spinal Manipulation Wont Cause Chest Injuries, Study Contends
10. Robotic Surgery Oversold on Hospital Websites, Study Contends
11. Preemies at Risk for Psychiatric Disorders as Teens, Study Contends
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/17/2017)... ... January 17, 2017 , ... ... the National Association of Music Merchants (NAMM) winter trade show, Booth #2876, at ... Etymotic’s ER•4® has long been the gold standard for high-definition, in-ear earphones. This ...
(Date:1/17/2017)... , ... January 17, 2017 , ... ... online continuing education for EMS and firefighting professionals, has released four new continuing ... These new courses are taught live in an online classroom and meet the ...
(Date:1/17/2017)... ... January 17, 2017 , ... SensorInsight ®, an Internet ... in the U.S.A. to offer Internet of Things (IoT) solutions based on ... sensor deployments such as monitoring solutions used to detect potentially hazardous conditions in ...
(Date:1/17/2017)... , ... January 17, 2017 , ... Livionex, Inc., a ... of a double blind clinical study for its dental gel that shows significant reduction ... brand of toothpaste containing triclosan. The study was conducted at the Beckman Laser Institute ...
(Date:1/17/2017)... ... January 17, 2017 , ... ... ranked among the top US security companies for consecutive years, today announced the ... brings a year-long independent board nomination process to a close and positions Lynx ...
Breaking Medicine News(10 mins):
(Date:1/17/2017)... , Jan 17, 2017 Research and Markets ... by Type (Innovative, Generic), Manufacturer (Captive, Merchant), Synthesis (Synthetic, Biotech), Product ... Global Forecast to 2021" report to their offering. ... The global active pharmaceutical ... from USD 157.95 Billion in 2016, growing at a CAGR of ...
(Date:1/17/2017)... WARSAW, Ind. , Jan. 17, 2017  Zimmer ... leader in musculoskeletal healthcare , today announced ... capitalizes on the strength of the Zimmer Biomet ... D. Delp will assume the position of ... of the Company. Mr. Delp previously served as Zimmer ...
(Date:1/17/2017)... , Jan. 17, 2017 Tempus, ... cancer care, and University Hospitals Seidman Cancer Center ... by making genomic data, advanced molecular analysis and ... researchers, physicians and healthcare providers. ... provide genomic and transcriptomic sequencing and analysis for ...
Breaking Medicine Technology: