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Issue III registry defines best syncope candidates for cardiac pacing
Date:6/26/2013

Athens, Greece 26 June 2013. Two important studies were released at the Late Breaking Clinical Trials session II at EHRA EUROPACE 2013. The PREFER AF study2 found that Oral anticoagulation is now used in over 85% of patients with atrial fibrillation (AF) eligible for therapy. And ISSUE (the International Study on Syncope of Uncertain Aetiology) determined that cardiac pacing is more effective in patients with presumed neurally mediated syncope (NMS) and asystolic episodes in which tilt table testing proves negative (TT-), than in patients in which the tilt table testing proves positive (TT+).

PREFER AF

The PREFER AF registry study, which provides a 'snapshot' of clinical practice across five European countries taken in 2012, revealed that novel oral anticoagulants are now used by 6.1% of AF patients, and that use of rhythm control mediations and catheter ablations have also increased.

"PREFER AF illustrates changes in management of patients with AF since the last ESC guidelines. The registry shows that oral anticoagulant therapy is now much more widely used than in the German Competence Network on Atrial Fibrillation (AFNET) and the Euro Heart Survey registries on AF and suggests that European clinicians are using guidelines well. The rapid uptake of new oral anticoagulants suggests that these drugs are filling a therapeutic gap," said Professor Paulus Kirchhof, presenter of the study from the University of Birmingham, UK. The investigators believe the study represents the largest European registry on AF to date.

The ESC Guidelines for the Management of atrial fibrillation3, published in 2010, incorporated several 'evolutionary' changes in the management of AF including the concept of active AF screening to initiate therapy before complications had occurred and furthermore emphasized that continuous oral anticoagulation was indicated for the majority of AF patients since almost all are at increased risk of stroke.


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Contact: Jacqueline Partarrieu
press@escardio.org
33-622-418-492
European Society of Cardiology
Source:Eurekalert

Page: 1 2 3 4

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