Navigation Links
Islet transplant may slow progression of atherosclerosis
Date:1/28/2013

Minimally invasive islet transplantation for patients with type 1 diabetes achieves insulin independence and reverses the progression of atherosclerosis in the first few years after transplant, according to a University of Illinois at Chicago study.

The research is published in the February issue of the journal Diabetes Care and is available online.

Patients with diabetes, particularly women, have a substantial increased risk of dying from ischemic heart disease, according to previous research. However, future cardiac events may be prevented with intensive glycemic control.

In the current longitudinal study, UIC researchers looked at changes over time in carotid intima-media thickness, or CIMT -- a marker for atherosclerosis -- in a group of type 1 diabetes patients without kidney disease or previous cardiovascular events.

"This is the first study to look at what happens to diabetes-related cardiovascular complications after islet cell transplantation alone without kidney transplant," said Kirstie Danielson, assistant professor in the UIC College of Medicine and School of Public Health, and lead author of the study, who noted that previous research has focused on metabolic changes and glycemic control after transplant.

The 15 adults (two men and 13 women) suffered from type 1 diabetes for more than five years and had hypoglycemic unawareness despite best efforts to manage insulin levels. The patients received a total of 27 islet transplants (one to three transplants each) and were followed from one to five years after their first transplant. CIMT was measured before and approximately every 12 months after the first islet transplant.

The researchers found a significant decrease in CIMT one year after islet transplant. The CIMT measures started to progress again -- slightly more than they would in healthy individuals without diabetes -- between 12 and 50 months. At 50 months, post-transplant the CIMT me
'/>"/>

Contact: Sherri McGinnis Gonzlez
smcginn@uic.edu
312-996-8277
University of Illinois at Chicago
Source:Eurekalert

Page: 1 2

Related medicine news :

1. JDRF-Helmsley Charitable Trust to fund islet encapsulation research at Diabetes Research Institute
2. Santa Monica Dermatologist, Dr. Ben Behnam, and Santa Monica Hair Transplant Expert, Dr. Sean Behnam, Launch Their New Websites Focused on Treatment of Acne, Skin Cancer, Laser Procedures and Hair Transplant
3. Obese Patients Urged to Lose Weight Before Kidney Transplant
4. Fecal Transplant to Cure Gut Infection?
5. Decline in available liver transplants expected
6. Stem Cell Transplants in Mice Show Promise for Lou Gehrigs Disease
7. New company applies regenerative medicine to corneal transplantation
8. Boomers With Hepatitis C Boosting Demand for Liver Transplants
9. Blood Cancer Patients May Benefit From New Transplant Technique
10. Face transplantation calls for reverse craniofacial planning
11. Reduced intensity regimen prior to marrow transplant better for older leukemia patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/25/2014)... 2014 The report “TS-1 (Colorectal Cancer) ... the current treatment landscape, unmet needs, current pipeline and ... an anti-cancer drug which is typically used for treating ... used for treating gastric cancer and pancreatic cancer. TS-1 ... drug was first approved in 1999 in Japan for ...
(Date:12/25/2014)... (PRWEB) December 25, 2014 The short film ... was created in honor of a true 9/11 hero, Welles ... film festivals including the 24 hours of Nuremberg International Short ... Bangladesh. , Actress, screenwriter and director Luciana Lagana ... this film together with her husband, Gregory Graham ...
(Date:12/25/2014)... 25, 2014 Recently, LunaDress.co.uk has updated its blog ... related accessories. Now, all of the models at LunaDress.co.uk come with ... groom lifts the wedding veil can turn out to be a ... A wedding veil can always bring surprise to a wedding. On ... how to choose veils for a big day . , ...
(Date:12/25/2014)... By Dennis Thompson ... -- Researchers could be closing in on a "fountain of ... improve the health of older adults, a new study suggests. ... when given a drug that targets a genetic signaling pathway ... maker Novartis report. The experimental medication, a ...
(Date:12/25/2014)... December 25, 2014 Residents at ... Community, recently showed their generous spirit by providing ... Catawba County Parenting Network- Grandparents Raising Grandchildren program. ... gathered around the largest Christmas tree on the ... purchased by residents of the Abernethy Village Association ...
Breaking Medicine News(10 mins):Health News:TS-1 Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 2Health News:TS-1 Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 3Health News:The True 9/11 Hero Story “Color of Honor” Premieres in Germany and Bangladesh: Luciana Lagana Plays the Mother of the Lead and Co-Produces with Blaise Dolcemaschio. 2Health News:The True 9/11 Hero Story “Color of Honor” Premieres in Germany and Bangladesh: Luciana Lagana Plays the Mother of the Lead and Co-Produces with Blaise Dolcemaschio. 3Health News:LunaDress Provides Professional Tips On Shopping Wedding And Prom Dresses 2Health News:Researchers Take 'First Baby Step' Toward Anti-Aging Drug 2Health News:Researchers Take 'First Baby Step' Toward Anti-Aging Drug 3Health News:Retirement Community Residents Make Impact During Holiday Season 2
... first to tackle different forms of the disease and help ... new vaccine is designed to trigger production of a range ... causing the disease. Scientists created the vaccine by ... types of malaria parasite, which is known to trigger production ...
... A vaccine to prevent anal cancer is safe and effective ... funded in part by the vaccine,s maker. Anal cancer ... sexually transmitted disease in the United States. Anal cancer is ... with HIV. , , Merck,s Gardasil vaccine is already ...
... 11-month-old partnership between UCSF and Pfizer, Inc., aimed at ... selected its first projects for funding and joint development. ... on experimental therapies developed by the UCSF scientists with ... hard-to-treat, often deadly conditions, including lung and prostate cancer. ...
... News) -- Moving to the beat of music actually helps ... Researchers at McMaster University in Canada played a series ... on an electronic drum pad while they listened while the ... whether the final beat was consistent with the preceding rhythm, ...
... WEDNESDAY, Oct. 26 (HealthDay News) -- The genes suspected of ... the developing brain before birth, according to a major genetic ... spotted hundreds of genetic differences between males and females still ... genes involved in the development of the brain, but now ...
... estimate, half of Americans are confronting a civil legal problem at ... advice, or an advocate in civil court, they may lose a ... They may lose out in a divorce, or in a billing ... those services depends not on their need but where they live, ...
Cached Medicine News:Health News:Multiple malaria vaccine offers protection to people most at risk 2Health News:HPV Vaccine Might Help Prevent Anal Cancers: Study 2Health News:UCSF-Pfizer partnership yields projects aimed at clinical trials 2Health News:UCSF-Pfizer partnership yields projects aimed at clinical trials 3Health News:UCSF-Pfizer partnership yields projects aimed at clinical trials 4Health News:Links to Mental Illness Seen in Fetal Brains: Study 2Health News:Access to legal aid depends a lot on where you live, report says 2Health News:Access to legal aid depends a lot on where you live, report says 3
(Date:12/22/2014)... 22, 2014  CytoSorbents Corporation (OTCQB:CTSOD), a critical ... purification technology to help fight deadly inflammation in ... worldwide, today announced the appointment of Dr. ... its Senior Vice President of Clinical Development, effective ... Di Russo is an accomplished pediatric cardiothoracic ...
(Date:12/22/2014)... MEMPHIS, Tenn. , Dec. 22, 2014   ... only automated, no-touch UV disinfection robot, announced today that ... GSA Schedule contract through November 2019.   ... to rapidly engage all levels of government purchasers, including ... facilities, as well as Homeland Security contacts purchasing solutions ...
(Date:12/22/2014)... STOCKHOLM , Dec. 22, 2014 ... Pharmaceuticals, Inc. today announced that the Committee for Medicinal ... Agency (EMA) has adopted a positive opinion for the ... of adult men with Peyronie,s disease with a palpable ... at the start of therapy. The use ...
Breaking Medicine Technology:CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 2CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 3CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 4CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 5TRU-D SmartUVC LLC Awarded General Services Administration Contract to Expand Government Customer Base 2Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 2Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 3Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 4Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 5Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 6
... found to be prevalent in cancer patients regardless of nutritional ... at Cancer Treatment Centers of America ... for vitamin D deficiency and aggressive vitamin D repletion should ... (Logo: http://www.newscom.com/cgi-bin/prnh/20090612/CTCALOGO ) , ...
... Jazz Pharmaceuticals, (Nasdaq: JAZZ ) sodium oxybate ... and the core symptoms associated with fibromyalgia, according to Phase ... Sleep Societies meeting in Seattle, WA. These data have ... for use of sodium oxybate in the treatment of fibromyalgia. ...
Cached Medicine Technology:Study Suggests Vitamin D Screening and Appropriate Supplementation Indicated for All Cancer Patients 2Data Suggest Sodium Oxybate Significantly Improves Pain and the Core Symptoms of Fibromyalgia 2Data Suggest Sodium Oxybate Significantly Improves Pain and the Core Symptoms of Fibromyalgia 3Data Suggest Sodium Oxybate Significantly Improves Pain and the Core Symptoms of Fibromyalgia 4Data Suggest Sodium Oxybate Significantly Improves Pain and the Core Symptoms of Fibromyalgia 5
Both versions of the UltraSling II provide immobilization for rotator cuff repairs, capusular shifts, Bankhart repairs, glenohumeral dislocations/subluxation and soft tissue repairs/strains....
Unique V-lock strapping system prevents roll and shifting to provide secure shoulder immobilization...
... Bird and Cronin, Inc. ... of Patient Footwear, Orthopedic ... Care Products. Our products ... quality and available in ...
... Effective spinal bracing is a critical component ... surgical stabilization. The Aspen® Lumbosacral Bracing System™ ... provide a high degree of immobilization, unparalled ... patients . . . even if they ...
Medicine Products: