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Isis Reports Strong Financial Results and Highlights for First Quarter of 2009
Date:5/7/2009

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Isis benefits financially as its partners advance drugs in development while also receiving upfront and royalty payments. This strategy provides cash to the Company while the drugs in Isis' pipeline mature in clinical development.

  • Isis received a $1 million milestone payment from Achaogen for the filing of an IND for Achaogen's aminoglycoside drug, ACHN-490.

Isis also benefits from its partnerships focused on developing and advancing certain RNA-based therapeutic technologies. These partnerships take advantage of Isis' dominant intellectual property estate, expertise, and ongoing innovation and allow Isis to participate in newly emerging approaches to RNA-based therapeutics and augment its active programs in these areas.

  • Isis received $1 million from Alnylam related to Alnylam's alliance with Cubist Pharmaceuticals, Inc.
  • Isis also earned a milestone payment from Alnylam related to Alnylam's clinical development of ALN-VSP in patients with advanced liver cancers.
  • Isis co-exclusively licensed its single-stranded RNA interference (ssRNAi) technology to Alnylam as part of a new strategic initiative to continue to develop the ssRNAi platform.

Regulus Therapeutics, Isis' and Alnylam's jointly owned company, continues to make significant progress in all areas of its business. Isis continues to support Regulus as it translates one of the most important new discoveries in biology into a novel approach for treating disease.

  • Regulus raised $20 million in a Series A financing in which Isis and Alnylam were the sole and equal investors in the financing.

Conference Call

At 08:30 a.m. Eastern Time today, May 7, Isis will condu
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SOURCE Isis Pharmaceuticals, Inc.
Copyright©2009 PR Newswire.
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