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Isis Reports Financial Results and Highlights for Fiscal year 2007
Date:3/13/2008

to treat cancer continue to

support the unique therapeutic potential of antisense drugs. Already

this year, OncoGenex reported Phase 2 results for OGX-011 in prostate

cancer.

* OncoGenex expects to report additional Phase 2 results for

OGX-011 in patients with cancer.

* OGX-011 will be further evaluated in prostate cancer with the

initiation of a Phase 3 study in patients with prostate

cancer.

* OncoGenex expects to initiate Phase 2 clinical studies of

OGX-427 that targets Hsp27 for cancer treatment.

* Lilly expects to begin Phase 2 clinical studies of LY2181308

that targets survivin for cancer treatment.

* The broad therapeutic potential of antisense drugs enables Isis to

discover drugs that are outside of Isis' core focus areas. Isis'

partners are instrumental in driving the clinical development of these

drugs.

* ATL1102, which targets VLA-4 to treat multiple sclerosis, is

currently in Phase 2 studies with results expected to be

reported this year.

* In addition to the highlighted drugs above, Isis and Isis' drug

development partners intend to initiate clinical studies on two new

antisense drugs.

* Isis also intends to advance two to four new drugs into development

within the next year.

Ibis

Ibis is committed to advancing the Ibis T5000 Biosensor System into larger commercial markets, including hospital-acquired infection control and clinical diagnostics. Early in 2008, Ibis achieved a key goal to establish a strategic partner in the diagnostics arena and to secure funding to support continued progress in commercial development.
* Ibis intends to continue expanding its customer base and to place at

least eight ad
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SOURCE Isis Pharmaceuticals, Inc.
Copyright©2008 PR Newswire.
All rights reserved

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