Navigation Links
Isis Reports Financial Results and Highlights for Fiscal year 2007
Date:3/13/2008

position significantly in 2007, strengthening its balance sheet and reducing its net operating loss.
* Isis refinanced its convertible debt, which extended the maturity of

the debt, strengthened the Company's balance sheet, and reduced its

cash interest payments by approximately $2.6 million annually due to

the lower coupon rate.

* Isis purchased Symphony GenIsis relatively early in the term of that

financing arrangement saving approximately $75 million in the

predetermined purchase price, regaining full ownership of mipomersen,

which Isis licensed to Genzyme, and the GCGR and GCCR drugs, which

Isis licensed to OMI.

* As a result of Isis' partnering strategy, the Company was able to

reduce its pro forma net operating loss guidance by $40 million over

the course of 2007.

Isis strengthened its leadership team with the addition of:

* Jeffrey M. Jonas, M.D. to lead Clinical Development, Preclinical

Development, Regulatory Affairs, and Quality Assurance and Compliance.

Dr. Jonas was formerly Chief Medical Officer and Executive Vice

President at Forest Laboratories, Inc.

Regulus Highlights

Isis and Alnylam founded Regulus Therapeutics LLC and hired senior management to lead the joint venture company in discovering and developing antisense drugs targeting microRNAs.
* Kleanthis G. Xanthopoulos, Ph.D., was appointed as President and Chief

Executive Officer of Regulus. Dr. Xanthopoulos is the co-founder and

former President and Chief Executive Officer of Anadys

Pharmaceuticals, Inc.

* Peter S. Linsley, Ph.D., was appointed as Chief Scientific Officer of

Regulus. Dr. Linsley was Executive Director of Cancer Biology at

Merck Research Laboratories, and was previously Vice President of

Research of Rosetta Inpharmatics.


'/>"/>

SOURCE Isis Pharmaceuticals, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26

Related medicine news :

1. New Study Reports High Injury Rates for Hotel Workers, Even Higher Rates for Women and Nonwhites
2. Haemacure Reports Third Quarter 2007 Results
3. First-Ever List of the 5,000 Fastest-Growing Businesses Reports Total Revenue of $194.5 Billion
4. Consumer Reports Analysis: Drugs for Nerve Pain, Fibromyalgia Effective, But Not Always Best
5. MDS Reports Third Quarter 2007 Results
6. Allied Healthcare Reports Strong Fourth Quarter, Flat Net Income for Fiscal 2007 vs. 2006
7. AtriCure Reports First Human Implant of the Cosgrove-Gillinov Left Atrial Appendage Occlusion System
8. NMHC Reports Fourth Quarter and Fiscal Year 2007 Financial Results
9. Blue Cross and Blue Shield of Florida Reports Eighteenth Consecutive Year of Positive Performance
10. ReBuilder Medical Technologies, Inc. Reports International Sales Expansion
11. AdCare Health Systems, Inc. Reports Discontinuation of Definitive Merger Agreement with Family Home Health Services, Inc.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/25/2014)... Oct. 23, 2014 (HealthDay News) -- Current osteoporosis ... younger postmenopausal women at risk for osteoporosis-related fractures, ... to prevent fractures, we need tools that help ... injuries so that we can target these at-risk ... Crandall, professor of medicine in the division of ...
(Date:10/22/2014)... October 22, 2014 At a time ... among parents and athletes at all levels, the ... change the current discussion where two powerful messages are ... therapies that result in full recoveries every day. , ... based in fact and research, UPMC and the Concussion ...
(Date:10/22/2014)... Medical Solutions , the nation’s ... announce that our co-founder and CFO, Scott Anderson, ... 100 for 2014. Anderson was also named to ... in the staffing industry,” in 2013.     , Under ... staffing company in the U.S., was named a ...
(Date:10/22/2014)... HealthDay Reporter , TUESDAY, Oct. ... three Ebola cases in Dallas. But, mental health specialists say ... President Barack Obama on Friday appointed an Ebola "czar" ... infected two Dallas nurses who cared for a Liberian man ... Hospital. But the U.S. cases are miniscule in the ...
(Date:10/22/2014)... Va. (PRWEB) October 22, 2014 ... Innovation , which is dedicated to distribute health ... of healthcare delivery worldwide announced the development of ... which patients expect when receiving healthcare. These are ... for patient-centered care: “providing care that is respectful ...
Breaking Medicine News(10 mins):Health News:Osteoporosis Screening Guidelines May Miss Younger Women at Risk 2Health News:University of Pittsburgh Medical Center Launches Initiative to Emphasize Concussions Are Treatable 2Health News:University of Pittsburgh Medical Center Launches Initiative to Emphasize Concussions Are Treatable 3Health News:University of Pittsburgh Medical Center Launches Initiative to Emphasize Concussions Are Treatable 4Health News:Medical Solutions Co-Founder/CFO Scott Anderson Named to Staffing Industry Analysts’ 2014 Staffing 100 2Health News:Medical Solutions Co-Founder/CFO Scott Anderson Named to Staffing Industry Analysts’ 2014 Staffing 100 3Health News:Ebola Anxiety: A Bigger Threat Now Than the Virus Itself 2Health News:Ebola Anxiety: A Bigger Threat Now Than the Virus Itself 3Health News:The Sullivan Institute for Healthcare Innovation Announces Release of Guiding Principles for Patient Experience-Centered Care 2
... be more appropriate to de-stress oneself, than going to a gym ... to tone up my body but it didn't work. Then I ... well. Finally, I put on my dancing shoes and I haven't ... here. ,Learning various dance forms like merengue, cha cha, ...
... Association (ADA) has warned that the diabetes threat is greater ... type 2 diabetes among middle aged Americans has doubled over ... obesity, the ADA said. ,An estimated two-thirds of ... world can now expect many more people to succumb to ...
... According to a report published in Ethnicity & Disease ... patients suffering from congestive heart// failures. ,Scientists ... on 23 African American who were admitted in New ... a mix of men and women with an average ...
... today welcomed the decision by the Tasmanian Government to ban ... and to not allow the// sale of fruit-flavoured cigarettes in ... a good example to the other States and Territories. ... Haikerwal said. ,“It removes another health hazard from ...
... stress experienced by children may hamper their brain. This ... disorder (PTSD), the component of the brain responsible for ... Chidlren finds it difficult to deal with stress and ... children in the study also had higher blood levels ...
... China's Yunnan Province, which has a large number of ... treatment //to more HIV/AIDS victims this year with traditional ... meeting that ended Friday, Yang Hongsheng, deputy chief of ... build more infrastructures, bringing the number of TCM AIDS ...
Cached Medicine News:Health News:Dance to De-stress 2Health News:Diabetes Threat Greater Than Feared 2Health News:Child Brain Likely To Be Harmed By Stress 2
(Date:10/25/2014)... , Oct. 24, 2014  The National Association ... latest results achieved by Kentucky,s ... The National Precursor Log Exchange (NPLEx) ... point of sale and helps flag meth offenders ... often set up NPLEx "watch lists" that notify ...
(Date:10/25/2014)... HOUSTON , Oct. 24, 2014   Metanome, ... of comprehensive metagenomic services and data analysis, was the ... Mass ) Phase I/II clinical trial of SER ... with recurrent Clostridium difficile infections (CDI). ... of Seres Health,s R&D and clinical programs. Such genomic ...
(Date:10/25/2014)... Research ... addition of the  "Global and Chinese Acne ... their offering.       (Logo: http://photos.prnewswire.com/prnh/20130307/600769) ... Industry Report 2014 is a professional and ... the global acne medication industry with a ...
Breaking Medicine Technology:Kentucky's NPLEx Technology Making Significant Progress 2Metanome Selected as Metagenomics Provider for Seres Health Clinical Trial 2Global and Chinese Acne Medication Industry Report 2014 2Global and Chinese Acne Medication Industry Report 2014 3
... , a medical device company developing intelligent cardiovascular diagnostic imaging ... an award of nearly $862,000 as part of the ... conjunction with the award, InfraReDx has committed to create 32 ... Tax Incentive Program was established in 2008 as part of ...
... 2010 A new study that reviews more than ... of health information technology (HIT) and electronic communications on ... suggest that simple electronic reminders are an effective and ... that show how HIT can be leveraged to more ...
Cached Medicine Technology:InfraReDx Awarded 2010 Tax Incentive From Massachusetts Life Sciences Center 2New CVS Caremark Study Finds Health Information Technology May Help Promote Adherence, But More Information and Direction Needed 2New CVS Caremark Study Finds Health Information Technology May Help Promote Adherence, But More Information and Direction Needed 3
More than 200 key diagnostic and treatment tables culled from Tierney's Current Medical Diagnostics and Treatment 2003....
Information on diagnosis and management of 500 common or important medical and surgical disorders....
Athouritative, on the spot answers for acute care and consultations....
The workhorse electric system....
Medicine Products: